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Science News for November 23, 2020


Understanding frustration could lead to better drugs

A new study by Rice University scientists has developed atomic resolution protein models that show frustration is necessary for protein function and can lead to better drug specificity. The models allow for the incorporation of co-factors like drug molecules, providing insight into why ligands bind best with specific proteins.

SourceRice University·JournalNature Communications·DateNov 23, 2020

Scientists regenerate skin with stem cells to see how DNA defects in kids cause cancer

Researchers used bioengineered models of patient-specific skin to study how inherited DNA defects cause skin damage and deadly squamous cell carcinoma in children with Fanconi anemia. The study identified key biological connections important to skin formation and function, leading to accelerated blistering and disease progression.

Unique Schwann cells: the eyes have it

Researchers have identified a new class of glial cells in the cornea, known as Schwann cells, with unique genetic properties that could help improve wound healing and nerve regeneration after surgeries and corneal transplants. The study's findings may also provide insights into conditions like dry eye and LASIK-related side effects.

SourceUniversity of Connecticut·JournalJournal of Neuroscience Research·DateNov 23, 2020

Shocks to seafood

The US seafood industry experienced a significant decline in catches, imports, and exports during the pandemic. Small-scale fisheries were more affected than large-scale production systems, highlighting the need for targeted federal support to preserve local operations and promote resilience.

SourceUniversity of California - Santa Barbara·JournalFish and Fisheries·DateNov 23, 2020

Medicaid expansion may result in earlier diagnosis of colon cancer

A new study published in the Journal of the American College of Surgeons suggests that Medicaid expansion under the Affordable Care Act may lead to earlier diagnoses of colon cancer. Researchers found improved access to care and enhanced surgical care for patients with colon cancer in states that implemented Medicaid expansion.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateNov 23, 2020

Nutritional quality of foods, beverages in movies

A study analyzed 250 top-grossing US movies from 1994-2018, comparing the nutritional quality of food and beverage depictions to dietary guidelines. The findings indicate that movie foods often exceed recommended levels of calories, added sugars, and saturated fats.

SourceJAMA Network·JournalJAMA Internal Medicine·DateNov 23, 2020

Treating type 1 diabetes in mice

A study published in PNAS reports a breakthrough treatment for type 1 diabetes in mice, utilizing a combination of haploidentical mixed chimersim and administration of gastrin and epidermal growth factor. This approach successfully reversed autoimmunity, augmented beta cell regeneration, and normalized blood glucose levels by reactivat...

SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateNov 23, 2020

Carbon nanocomposites are now one step closer to practical industrial

The study introduces a new generation of multifunctional materials created by adding carbon nanoparticles to polymer matrices, allowing for self-sensing properties. This technology has the potential to replace sensors in weight-critical systems and manufacture electrically conductive materials for various applications.

Tracing the flow of cerebrospinal fluid

Researchers have discovered that cerebrospinal fluid (CSF) can swell immediately after an injury or stroke, leading to a more efficient clearance of toxic proteins from the brain. This breakthrough could lead to new insights into health and disease, as well as novel treatments for neurodegenerative disorders.

A new beat in quantum matter

Researchers demonstrate the existence of exotic Bloch oscillations in crystals with intrinsic non-Abelian fields, characterized by a multiplication of the oscillation period. These phenomena are perfectly synchronized with internal states of the crystal and shed new light on topological quantum matter.

SourceUniversité libre de Bruxelles·JournalNature Communications·DateNov 23, 2020

Researchers identify genetics behind deadly oat blight

A multi-institution team identified the genetic mechanisms enabling the production of Victorin, a deadly toxin causing Victoria blight in oats. The study discovered that Victorin genes are scattered across repetitive regions in the pathogen genome, expanding the potential for small molecule discovery.

SourceCornell University·JournalProceedings of the National Academy of Sciences·DateNov 23, 2020

Nature is widely adapted to current climate -- making it harder to adjust to a new one

Researchers analyzed a massive dataset of seasonal events across the former Soviet Union and found that species' activities fail to keep up with their cues due to past evolution. Local adaptation patterns result in a massive imprint on nature's calendar, making geographic variation in seasonal timing more pronounced in spring and less ...

SourceUniversity of Helsinki·JournalProceedings of the National Academy of Sciences·DateNov 23, 2020

Growing risks of STIs in over-45s

A study has found that middle-aged and older adults are at risk of contracting STIs due to negative attitudes and limited knowledge about their sexual health needs. The report's findings highlight four critical areas where interventions can address gaps in current healthcare provision: awareness, access, knowledge, and stigma.

Making sense of a universe of corn genetics

Researchers have developed a predictive model to guide plant breeders in selecting suitable corn varieties based on genomic analysis. The study focused on predicting eight corn traits using shoot apical meristem (SAM) analysis, achieving accuracy ranging from 37% to 57% across the eight traits studied.

SourceIowa State University·JournalPlant Biotechnology Journal·DateNov 23, 2020

New clues shed light on importance of Earth's ice sheets

Researchers found subglacial waters in Antarctica and Greenland have higher concentrations of essential trace elements, challenging scientists' understanding of the Earth's geochemical processes. These discoveries may significantly impact the development of healthy ecosystems and the ocean waters receiving ice sheet meltwater.

SourceFlorida State University·JournalProceedings of the National Academy of Sciences·DateNov 23, 2020

Climate change presents new challenges for the drinking water supply

The Rappbode Reservoir in Germany is facing new challenges due to climate change, with projected temperature increases that could lead to significant changes in the reservoir's physical structure. This could result in increased oxygen demand, intensified nutrient dissolution, and algae growth, posing a risk to the drinking water supply.

SourceHelmholtz Centre for Environmental Research - UFZ·JournalThe Science of The Total Environment·DateNov 23, 2020

A hunger for social contact

A new study from MIT finds that long periods of social isolation activate the brain's substantia nigra region in a way similar to food cravings. The researchers used an innovative isolation method to induce strong feelings of loneliness, and found that the resulting craving signal was correlated with self-reported levels of loneliness.

SourceMassachusetts Institute of Technology·JournalNature Neuroscience·DateNov 23, 2020

Milky Way family tree

A team of astrophysicists has created a complete family tree of the Milky Way, revealing a previously unknown galaxy collision that permanently altered its appearance. The researchers used advanced computer simulations and artificial intelligence to study the merger history of the galaxy.

SourceHeidelberg University·JournalMonthly Notices of the Royal Astronomical Society·DateNov 23, 2020

Lab closed? Head to the kitchen

A mechanical engineer uses pancake batter to teach students about viscosity, while a group at ETH Zurich studies the stability of foam in beers and breads. The research reveals diverse mechanisms behind fluid dynamics, potentially leading to new materials and applications.

The science of windy cities

A team from Oklahoma State University developed techniques to model environmental hazards for autonomous aircraft, while another group at the University of Surrey investigated building wakes to enhance air quality. Researchers also found an unbalanced exchange flow in natural ventilation systems, which can slow down cooling.