A breakthrough discovery by scientists at Integrated Tissue Dynamics LLC has provided a biological rationale for fibromyalgia. Researchers found an increase in sensory nerve fibers around specialized blood vessel structures in the skin of female patients with fibromyalgia, which may be driving the reported symptoms.
A new study reveals that certain types of chronic pain may be caused by signals from the skin itself, rather than damage to nerves within the skin. Skin cells generate increased amounts of a lesser-known 'beta' isoform of CGRP, which may be sending pain signals to remaining sensory nerve fibers in the skin.
A groundbreaking study published in the journal Pain reveals that humans have a unique sensory system located in blood vessels and sweat glands, which can provide conscious tactile information. This discovery may contribute to understanding mysterious pain conditions such as migraine headaches and fibromyalgia.