N of One: Autism Research Foundation

Small non-profit's unconventional approach offers new hope with autism suramin trial

A double-blind, placebo-controlled trial tested the 100-year-old drug suramin in boys with autism, showing significant improvements in language, social interactions, and restricted behaviors. The study's findings challenge the conventional view of autism as a fixed, genetically-driven condition and suggest a treatable metabolic syndrome.

SourceN of One: Autism Research Foundation·JournalAnnals of Clinical and Translational Neurology·DateMay 26, 2017

Baylor study aims to find out why some children's autism symptoms improve with antibiotics

A national study led by Baylor College of Medicine aims to understand the link between antibiotic use and improvements in autism symptoms in some children. The research, funded by N of One: Autism Research Foundation, will examine the gut microbiome and metabolome for two years to identify potential causes and effects.

SourceN of One: Autism Research Foundation·DateDec 1, 2016

Child with autism improves with antibiotic; prompts new investigations into autism

A child with autism improved dramatically while taking an antibiotic for strep throat, prompting a quest by the parent to understand the phenomenon. The collaboration led to a scientific conference and special issue in a scientific journal featuring articles on the microbiome's involvement in autism.

SourceN of One: Autism Research Foundation·JournalMicrobial Ecology in Health and Disease·DateMar 24, 2015