Researchers discovered that abnormal expression of the WT1 gene is linked to nearly 70% of breast cancers, which may lead to new treatments. The study suggests restoring functional tumor suppressor genes like WT1 could help combat breast cancer.
Researchers at Oregon Health & Science University shed light on the molecular mechanisms underlying long-term potentiation, a key process for memory formation. The study reveals that CaM-KII plays a critical role in this process, enabling persistent changes in synaptic strength and storage of information.
Oregon Health Sciences University professor James T. Rosenbaum suggests two solutions to improve scientific expert testimony reliability: appointing experts or empaneling a group to advise the court. Using silicone breast implant litigation as an example, he emphasizes the importance of neutral expert panels and conflict disclosure.
A recent study published in the Journal of the American Medical Association found that one child asphyxiated in a window covering cord every 27 days between 1981 and 1995. The most common scenarios involve infants in cribs near windows or toddlers suspended from pull cords after jumping or falling nearby.
Researchers at Oregon Health & Science University found that adenosine triphosphate (ATP) stimulates pain-sensing nerves by binding to a receptor called P2X3 on nerve cell membranes. This discovery may pave the way for the design of new pain-relieving drugs.
A team of researchers from Oregon Health & Science University has identified three gene regions in mice that are linked to an increased risk of physical dependence on alcohol. The study's findings could lead to a better understanding of alcoholism and the development of new treatments.
Researchers at Oregon Health Sciences University discovered how a mutated agouti gene leads to overeating and excess body fat in mice. The study shows that the agouti gene, when expressed in brain cells, disrupts a hormonal signaling pathway that regulates feeding behavior.
A year-long study led by Oregon Health Sciences University found that a drug prevention program called ATLAS reduced anabolic steroid use among high school football players. The program included educational sessions on risks and benefits of steroids, proper sports nutrition, and resistance to peer pressure.
A new hormonal drug combination allows post-menopausal women to get the benefits of estrogen without experiencing menses-like bleeding. The therapy significantly increases bone mineral density and improves blood cholesterol levels.
A recent study by researchers at Oregon Health Sciences University found that beta-carotene supplements did not increase immune cell counts in HIV-infected patients. The study, led by Dr. Gregg O. Coodley, concluded that high doses of beta-carotene are not recommended for HIV-infected patients.
Researchers at Oregon Health & Science University discovered a natural brain chemical called orphanin FQ (OFQ) that counteracts the effects of opioids. This finding provides hope for developing new therapies to alleviate opioid-related side effects and treat addiction.
Researchers at Oregon Health Sciences University identify a new family of molecules regulating attention and cognitive functions. The SK channels play a prominent role in controlling cell firing and are expressed abundantly in brain regions responsible for cognition.