Articles tagged with Bioengineering
Recent advancements in animal models, organoid models, and bioengineered organoids have provided new tools for studying primary sclerosing cholangitis. These models replicate the effects of bile retention and inflammation, enabling studies of disease mechanisms, drug screening, and preclinical evaluation.
Researchers at Stanford University have developed a new approach called MIDAS, which enables the creation and testing of proteins in just 24 hours. This eliminates the need for labor-intensive cloning processes, allowing for faster and more cost-effective evaluation of protein variants.
Researchers are developing a multi-organ model on a chip to study the complex interactions between organs, hormones, and cells in diabetes and dementia. The GlucoBrain project aims to understand how signals move between the brain, gut, and pancreas, potentially leading to new treatments for millions affected by these diseases.
A protein from tardigrades has been found to protect synthetic cell membranes during dehydration, allowing them to survive rehydration. This discovery could lead to a way to store and transport biological microfactories, revolutionizing the production of medicines and other valuable molecules.
The Hong Kong University of Science and Technology (HKUST) researchers have developed a revolutionary DNA-guided CRISPR-Cas system that can programmably target RNA molecules, offering improved accuracy in rapid infectious disease testing and advancing antiviral treatments.
The partnership aims to establish a next-generation C1 biofoundry at DTU to convert CO2, CO, and methane into valuable products. This technology has the potential to reduce industrial emissions and enable circular, climate-positive solutions.
Researchers have developed a new class of biodegradable, all-metal microrobots that can penetrate tissue and deliver medications without causing damage. These microrobots demonstrate both strength and safety in testing on mice, paving the way for potential applications in drug delivery and biopsy procedures.
Researchers at MIT have found that chromatin can exist in two different categories: constrained and free, which affects its interaction with genes and DNA regulatory sequences. This study provides insight into gene regulation and DNA repair processes.
The Boyce Thompson Institute has received a multi-year award from the USDA's FANE program to expand access to biotechnology education for K-12 students. The P-BIOTEK initiative will create hands-on learning opportunities and community science programs to introduce students to plant biotechnology, bioengineering, and science communication.
Researchers at MIT discovered that gene circuits can reshape DNA folding and affect gene expression in human cells. The study found that rearranging genes along a DNA strand, or 'gene syntax,' can amplify or suppress the expression of neighboring genes.
Motif Neurotech has received FDA approval to begin the first clinical trial of its therapeutic BCI device, DOT, for treatment-resistant depression. The study will test the device's effectiveness in delivering electrical stimulation to brain circuits linked to depression.
Researchers at Linköping University developed a digital twin model to predict alcohol consumption and drinking patterns. The tool uses data from exhaled breath, blood, and urine samples to generate individualised results, providing a more accurate picture of when a person last drank.
A team of researchers at The University of Osaka has created a wireless EEG transmission system that can operate without external power sources. The system harnesses energy from the temperature difference between the human body and surrounding air, allowing it to function reliably even in hot summer conditions.
Researchers created a microfluidic device to measure cell size and stiffness, enabling the analysis of large numbers of cells quickly. The new method uses time-of-flight measurements to determine cell stiffness, with potential applications in disease diagnosis and prognosis.
Researchers will use DNA-encoded chemical libraries and artificial intelligence to screen hundreds of millions of potential drug compounds, identifying those most likely to succeed in treating Alzheimer's. The project aims to shorten the timeline for identifying new treatments, bringing them to patients faster and with greater precision.
A research group developed an optimized signal transmission system for implantable medical devices, improving accuracy and strength of wireless signals. The approach uses ultra-wideband communication to coordinate multiple implants and reduce signal distortion, enabling more effective healthcare applications.
A University of Texas at Arlington researcher is leading a study investigating cardio-sarcopenia, the combined loss of heart and muscle health in aging adults. The grant aims to uncover how heart dysfunction and muscle loss interact and detect biomarkers for earlier intervention.
Researchers at University of Michigan created a stem cell model that produces a yolk-sac-like structure in a human embryo, mimicking early pregnancy loss. The model uses mechanical signals to guide development and does not require genetic manipulation.
A new MIT study suggests that exposure to NDMA, a chemical contaminant in drinking water and some medications, can cause cancerous mutations more severely in children than adults. The researchers found higher rates of DNA damage and cancer in juvenile mice exposed to low levels of NDMA.
Researchers create living biohybrid miniature robots that solve traditional engineering trade-offs between structural rigidity and environmental adaptability. These biological engines utilize embodied intelligence to navigate complex terrains and achieve performance metrics rivaling state-of-the-art synthetics.
Researchers at USC, Caltech, and UC Irvine have developed a two-way brain interface that allows patients to control wearable robotic legs using their thoughts. The system accurately detected brain signals indicating the intent to walk about 92% of the time and restored walking sensations with about 93% accuracy in an early proof-of-con...
Duracyte's technology uses an implantable device to produce therapeutic proteins continuously inside the human body, replacing injections and infusions with a single device. The device can sense biological signals, monitor tumor environments and adjust therapeutic output in real time.
Binghamton University has seen significant improvements in its graduate school rankings, with nearly three dozen programs earning national recognition. The university's Systems Science and Industrial Engineering program has been named the #31 Industrial and Systems Engineering graduate program in the US.
Anand Ramamurthi, Lehigh's Peter C. Rossin Professor of Bioengineering and chair of the Department of Bioengineering, has been elected to the AIMBE College of Fellows for his groundbreaking work in regenerative technologies that can repair damaged tissues without surgery. His research aims to develop nonsurgical nanomedicines to treat ...
The Chancellor’s Innovation Fund Awards support cutting-edge research and development projects across various fields. Faculty recipients will use the funding to refine their technologies, build prototypes, and assess market opportunities. The awards aim to bridge publicly funded academic research with private financing, fostering entre...
Researchers at the University of Pittsburgh have developed a new manufacturing strategy to precisely control the formation of laser-induced graphene on polymers. This allows for the creation of flexible microelectrodes and neurochemical biosensors with robust electrical and electrochemical performance.
Researchers at the University of Mississippi have developed a new method for delivering cancer-fighting drugs using 3D-printed nanocarriers, which can target specific tumor sites and minimize side effects. This innovative approach has shown promising results in killing cancer cells and reducing the impact of traditional chemotherapy.
A new bioinformatics tool, MPGK, integrates MR, PRS, GO, and KEGG analyses into a single reproducible workflow, reducing technical barriers for researchers. The tool successfully identified causal relationships between diabetes and psoriasis using publicly available datasets.
A team at Westlake University developed a high-throughput platform for engineering fast-acting covalent protein therapeutics, overcoming a fundamental limitation in the field. The platform enables rapid and irreversible target engagement with improved efficacy and safety.
A team of researchers, led by Bistra Iordanova and Liang Zhan, are developing multiscale models of brain metabolism to predict cognitive decline and dementia. They will analyze data from brain imaging, blood flow, and neural activity to identify metabolic changes that affect brain function in aging.
A five-year field study shows that small, repeated additions of biochar combined with water-saving irrigation can significantly reduce methane emissions from rice paddies over time while maintaining strong crop yields. Continuous application maintained and strengthened methane reduction, producing net negative emissions in some cases.
Aging is redefined as a systems-level failure rather than molecular defects, highlighting the need for coordinated modulation of biological networks. The International Conference on Targeting Longevity 2026 explores new translational strategies and industrial opportunities by focusing on resilience.
Researchers found that combining biochar with beneficial bacteria significantly improves phosphorus availability, reshaping plant development and increasing crop yields in greenhouse-grown cherry tomatoes. The study also showed that this approach can enhance soil fertility and crop productivity without increasing fertilizer inputs.
Researchers are developing snail-inspired soft robots to deliver targeted therapy directly to tumor sites in bowel cancer patients. The robots aim to increase drug bioavailability and reduce off-target toxicity., Transforming colorectal cancer treatment by enabling precise drug release at tumour sites.
The Hybrid Oxygenation Bioelectronics system, or HOBIT, shields cells from the immune system while providing access to oxygen and nutrients. The compact device supports higher cell densities in a smaller space, enabling the production of multiple biologic molecules simultaneously.
The latest SLAS Technology volume showcases how AI, automation, and portable technologies are transforming drug discovery and diagnostics. This advancement enables the development of innovative therapeutic solutions and improved patient care.
A new study by Beijing University of Chemical Technology proves that feeding methane to bacteria outperforms traditional soy and fish meal in both ecological savings and financial returns. The bacterial alternative eliminates the need for arable land and fresh water, effectively halting deforestation and marine depletion.
Researchers redesigned a key component of lipid nanoparticles to steer particles toward lymph nodes, reducing off-target delivery. This advancement could make mRNA vaccines more efficient, potentially achieving strong immune protection at lower doses.
Health Engineering combines engineering principles with life sciences to address pressing global health challenges, focusing on prevention, precision intervention, and long-term health maintenance. The journal publishes interdisciplinary research across various fields, including biomaterials, synthetic biology, and precision medicine.
Southwest Research Institute's new facility supports pharmaceutical development, bioengineering research, and streamlined clinical supply production. The facility enhances regulatory efficiency, quality systems, and communication between scientists.
Researchers developed a novel composite material that combines biochar, carbon nanotubes, and iron carbide, significantly accelerating the breakdown of antibiotics in water. The system achieved up to 15 times higher removal rates compared to conventional materials, while requiring substantially less energy.
Researchers developed in vitro and in vivo models to track cartilage-to-bone transition, identifying key signaling pathways and transcription factors involved. The study found that some cartilage cells can transition into bone-like cells, challenging the traditional view of bone cell origin.
A new study reveals that transforming biomass from dedicated energy crops into biochar could provide a cost-effective and scalable solution for removing carbon dioxide from the atmosphere, helping China move closer to its carbon neutrality goals. Biochar can lock carbon in soils for decades or even centuries while improving soil health.
Researchers developed Neuronal Type Assignment from Connectivity (NTAC) to accurately assign neuronal cell types based on synaptic wiring patterns. NTAC outperformed traditional morphology-based approaches in identifying neuron types, especially in complex brain regions.
Researchers developed a specially engineered biochar made from sewage sludge that significantly enhances plant growth when combined with beneficial bacteria. The biochar-bacteria combination improved nitrogen cycling and increased the abundance of beneficial soil microbes, leading to greater plant nutrition and growth.
Researchers at Rice University developed a safe bioelectronic sensor using naturally occurring polymer chitosan to effectively communicate with bacteria. The system uses a hydrogel to trap bacteria near an electrode, generating a stable electronic current when exposed to target substances.
A new study identifies a previously unknown brainstem pathway controlling hand and arm movements, revealing a multi-stage pathway integrating signals from the cortex, brainstem, and spinal networks. This finding may lead to new therapies for stroke rehabilitation, providing additional targets for neuromodulation treatments.
Recent advances in photonic nanomaterials and healthcare devices have led to the development of wearable and implantable medical devices. These devices utilize light for precise manipulation of cells and tissues, offering new possibilities for early disease detection, light-based therapies, and personalized precision medicine.
A conductive bioglue was developed to ensure firm adhesion and stable electrical signaling within the human body. It overcomes challenges in connecting damaged tissues or attaching bioelectronic devices, promoting muscle and nerve regeneration and stable implant stability.
Researchers create living tissue at near-physiological cell density using a new bioprinting strategy called embedded 3D printing in a cell-dense suspension (EPICS). The method enables the precise fabrication of perfusable channels and dense cellular environments, mimicking real organs.
Researchers developed a new noninvasive brain stimulation technique by combining focused ultrasound with electrical stimulation, producing stronger, targeted brain responses. This approach, called transcranial electro-acoustic stimulation, clarifies conflicting results in the field and introduces a new approach to noninvasive brain sti...
Engineers at the University of Pennsylvania have developed LIBRIS, an automated microfluidic platform capable of generating lipid nanoparticle formulations at high speed and scale. This enables the creation of large, systematic datasets needed to train predictive AI models, accelerating the design of lipid nanoparticles for mRNA delivery.
A novel plant-based approach uses lettuce chloroplasts to produce functional GLP-1 peptides, paving the way for more affordable and better-tolerated oral medications. This method bypasses hurdles such as manufacturing cost, delivery system, and side effects associated with conventional approaches.
Scientists create fluorescent nanoplastics that resemble real-world plastics in morphology, enabling real-time tracking and studying chronic exposure effects. The study reveals that smaller particles retain longer in the body, highlighting the need for further research on health risks due to microplastic ingestion.