Articles tagged with Bioengineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A team of researchers found that co-cultivating common bean plants with fragrant bush basil increases the expression of a key gene in plant defense mechanisms, reducing egg-laying activity of agricultural pests. This natural pest control method uses VOCs emitted by bush basil to attract beneficial insects and trigger plant defenses.
The journal is seeking high-quality submissions that explore the potential of voice and speech analysis in diverse medical applications. Submissions focus on acoustic and voice analysis techniques, voice or vocal phenotyping, and vocal biomarkers in health and medicine.
Researchers from Trinity College Dublin develop a method to harness structural colour using microfabrication technique, enabling ultra-sensitive materials for environmental sensing and biomedical diagnostics. The breakthrough also paves the way for next-generation medical sensors that can track biochemical changes in real-time.
Researchers at Washington University in St. Louis have developed a new type of bioplastic, called LEAFF, which is strong, biodegradable, and printable. This innovation uses cellulose nanofibers to address the limitations of current bioplastics and has potential applications for sustainable packaging.
A new silicone patch with star-shaped microneedles, called the ExoPatch, distinguishes melanoma from healthy skin in mice, capturing cancer biomarkers from exosomes. The test shows promise for early detection of the most aggressive form of skin cancer without a biopsy or blood draw.
A new AI model called RiboNN predicts translation efficiency of mRNA sequences, accelerating the development of mRNA therapeutics. The tool helps predict how much protein cells will produce, minimizing trial-and-error experimentation.
A study published in Journal of the Mechanical Behavior of Biomedical Materials found that wrinkled skin is caused by its tendency to buckle under pressure due to age-related changes in its mechanical properties. As people age, their skin becomes more prone to wrinkles as it stretches and contracts in different directions.
Recent advances in biofabrication and biomedical electronics have led to the development of biohybrid-engineered tissue (BHET) platforms, turning passive constructs into intelligent systems. These platforms show promise in diverse applications, including brain organoids and cardiac tissues, blurring the line between biology and machine.
A new approach by MIT researchers allows scientists to efficiently estimate how combinations of treatments will affect a group, enabling fewer costly experiments while gathering more accurate data. The framework considers the scenario where all treatments are assigned in parallel and controls the outcome by adjusting treatment rates.
Researchers at Kyoto University have created a microphysiological system capable of simulating different regions of human lungs, including the airway and alveoli. This breakthrough enables accurate modeling of viral pathologies and holds promise for personalized treatment of respiratory diseases such as COVID-19.
A team at Binghamton University has developed a process to convert food waste into biodegradable plastic, reducing greenhouse gas emissions and offering a sustainable alternative. The process utilizes bacteria to synthesize polyhydroxyalkanoate (PHA) plastic, which can be harvested and shaped into various products.
A team led by University of Houston engineer Tianfu Wu aims to find better biomarkers for ovarian cancer using autoantibodies and machine learning. By detecting ovarian cancer earlier, mortality rates could be reduced by 10-30%.
Researchers at RCSI University of Medicine and Health Sciences have developed a 3-D printed implant that delivers electrical stimulation to injured areas of the spinal cord, enhancing nerve cell growth. The study has shown promising results in lab experiments and may enable new medical devices for traumatic spinal cord injuries.
A novel, needle-type biosensor allows for real-time monitoring of sucrose uptake in plants, revealing light-dependent stomatal uptake and daily rhythms. The sensor's high sensitivity and stability enable the detection of subtle physiological events, shedding new light on plant biology.
In a small clinical study, users of this prosthesis navigated more easily and said the limb felt more like part of their body. The new system is directly integrated with the user’s muscle and bone tissue, enabling greater stability and control.
Researchers developed a controlled 'living' click polymerization system to achieve well-defined polymers with narrow dispersity, enabling bidirectional synthesis of ABA-type block copolymers. The method leverages copper-catalyzed azide–alkyne cycloaddition and initiators to selectively drive monomer addition in a controlled manner.
Researchers discovered a unique nanostructure in blue shark skin that produces their iconic blue coloration, which also suggests a potential capacity for color change. Tiny changes in guanine crystal spacing can alter the shark's body color to suit its environment.
The Buck Institute is pioneering a cloud-based platform to simulate the dynamic behavior of microbial cells, overcoming current whole-cell models' limitations. The SIMBA project aims to advance our understanding of bacterial behavior and address critical challenges in biomanufacturing and national security.
A research team led by Professor Joongoo Lee successfully expanded ribosome range to produce ring-shaped backbones in proteins. This breakthrough could open doors to novel therapeutics and advanced biomaterials.
A new computational method combines 4D flow MRI, CFD, and data assimilation to estimate blood flow in brain aneurysms with greater accuracy and efficiency. The approach focuses on the aneurysm region, reducing computational cost while improving flow estimation.
Chihtong Lee's research on retractor blade geometry explores how small design changes can improve patient recovery after spinal surgery. Her work, conducted in collaboration with Baylor College of Medicine, showed that blades with soft, biocompatible coatings significantly reduced tissue stress and postoperative complications.
Researchers have developed novel three-dimensional liver organoids using bile acids, which retain hepatocyte-like features and can be sustained in long-term cultures. These organoids demonstrate a unique gene expression profile similar to fetal hepatocytes and support replication of hepatitis viruses.
Researchers developed an AI-informed method for rapid protein evolution, integrating structural and evolutionary constraints. The approach, AiCE, outperforms traditional methods in predicting high-fitness mutations, enabling efficient protein redesign and applications in precision medicine.
Researchers at the University of Sydney developed a biological 'artificial intelligence' system called PROTEUS, which can accelerate cycles of evolution and natural selection to create molecules with new functions in weeks. The system has potential applications in finding new medicines and improving gene editing technology like CRISPR.
Scientists have developed a new tool named scICE to tackle the stability problem in single-cell RNA sequencing data. The tool provides a way to validate clustering outcomes mathematically, ensuring higher confidence in conclusions drawn from single-cell data.
Researchers from Pusan National University have developed engineered bacterial vesicles that use a novel surface-displaying protein to selectively target and eliminate E. coli and S. aureus bacteria. These vesicles, derived from lactic acid bacteria, offer a promising alternative to conventional antibiotics.
A new hydrogel-based platform has been developed to preserve live patient-derived tumor tissues in the lab, enabling more accurate testing of cancer treatments. The approach, which uses customizable bioengineered hydrogels, has been shown to retain key features of the original tumor environment.
Researchers developed a miniature 'leukemia-on-a-chip' device that recreates human bone marrow and immune system to predict cancer immunotherapy success. The device enables real-time observation of how immunotherapy drugs interact with cancer cells in an environment closely mimicking the human body.
Researchers at Iowa State University developed a new internal barrel design for the 'gene gun' technology, improving its efficiency by up to 50 times. The Flow Guiding Barrel reduces particle loss and uneven distribution, enabling more consistent and reliable genetic material delivery into plant cells.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
Researchers successfully engineered oilseed crop Camelina to produce high levels of astaxanthin, a valuable red antioxidant used to color farmed salmon and shrimp. The plant-derived pathway proved more efficient and cleaner than earlier bacterial methods, reaching over 47 micrograms per gram of seed.
Researchers from Binghamton University confirm the long-held 'urban myth' that saltwater dries out skin, increasing tissue stiffness and stress. A simple solution to alleviate tightness is taking a shower after coming out of the ocean.
Researchers have developed a method to transform polyethylene terephthalate (PET) plastic waste into paracetamol using genetically reprogrammed E. coli bacteria. The new process creates virtually no carbon emissions and can be completed in under 24 hours.
Bio Integration has a new institutional partner, University of South China's Institute of Sports Medicine, Fudan University, to support its interdisciplinary research in biomaterials, regenerative medicine, and translational healthcare. Professor Chaozong Liu joins as Co-Editor-in-Chief to shape the journal's editorial direction.
International Journal of Extreme Manufacturing (IJEM) achieves a new Impact Factor of 21.3, surpassing 20 for the first time and maintaining its position as top journal in the field. IJEM has attracted submissions from 853 institutions in 81 countries.
Bioengineering researchers at Harvard John A. Paulson School of Engineering and Applied Sciences developed a soft, thin, stretchable bioelectronic device that can be implanted into a tadpole embryo's neural plate, recording electrical activity from single brain cells with millisecond precision.
Scientists replace toxic additives in hydrogels with D-sorbitol, a safe sugar alternative found in chewing gum, to create bioelectronic devices that are soft, safe, and integrated with natural tissue. The new material has increased biocompatibility and improved electronic performance.
The Terasaki Institute and California State University, Northridge (CSUN) have launched a new collaboration initiative that brings advanced hands-on laboratory experience to CSUN Biology graduate students. Participating students will work alongside leading scientists on projects in various fields of biomedical research.
A new microscope, QIScope, significantly improves bioluminescence imaging by detecting extremely low levels of light. It offers higher sensitivity, improved resolution, and a wider field of view, allowing researchers to track subtle changes in living cells over extended periods.
Researchers have developed a new tool using quartz crystal microbalance with dissipation monitoring to study DNA-lipid interactions. The technique revealed insights into the attachment and integration of DNA nanostructures with lipid membranes, influencing cellular functions such as drug delivery and treatment precision.
A study by University of Fukui researchers reveals that two adjacent gene pairs in Neurospora crassa regulate antiviral response and symptom induction via RNA editing. The findings indicate that the modification of master transcription factor genes is crucial for controlling fungal antiviral responses.
A joint research team from POSTECH and Hanyang University developed a personalized stimulation control mechanism using evoked compound action potential feedback mechanisms to treat urinary disorders. This technology enables precise adjustment of tibial nerve stimulation in real-time, based on individual nerve responses, improving patie...
Researchers from Florida Atlantic University and the German Electron Synchrotron mapped the internal structure of blacktip sharks in unprecedented detail, discovering a microscopic 'sharkitecture' composed of densely packed collagen and bioapatite. This intricate structure gives cartilage surprising strength while allowing flexibility.
Antonios Mikos, a leading expert in biomaterials and tissue engineering, has been elected to the European Academy of Sciences. He is recognized for his groundbreaking work in regenerative medicine, controlled drug delivery, gene therapy, and disease modeling.
Researchers at the University of Arizona have developed a longer-lasting, 3D-printed wearable capable of providing comprehensive physiological data. The device continuously tracks and logs water vapor and skin emissions to monitor dehydration, metabolic shifts, and stress levels.
Researchers at KAUST created an electrochemical sensor that detects vitamin D deficiency using MXene-antibody hybrid biosensor device. The sensor has a detection limit of 1 picogram per milliliter, making it suitable for point-of-care testing in remote healthcare centers.
Researchers at UC San Diego's Scripps Institution of Oceanography developed a gel called SNAP-X that releases chemical cues encouraging coral larvae settlement. In laboratory tests, SNAP-X increased coral settlement by up to 20 times compared to untreated surfaces, offering a promising solution for coral reef restoration efforts.
A new AI model can predict protein location in human cells with high accuracy, enabling faster diagnosis of diseases like Alzheimer's and cancer. By combining protein sequence analysis with computer vision, the model can pinpoint proteins' locations at the single-cell level.
Researchers developed a rapid fluorochromic sensing method for detecting tertiary amines and opioids, enabling faster and more accurate analysis. The new approach uses photoinduced charge-transfer complexes to differentiate between structurally similar amines based on their substituents and molecular flexibility.
Engineers at Princeton University and Georgia Institute of Technology have created a method to reinforce structures without creating new weaknesses. The approach uses microstructures designed to protect against multiple loads, allowing designers to counter various stresses simultaneously.
Researchers at UC San Diego create a simple approach to rapidly check on human gene changes by turning everyday bacteria into living test tubes. This technique, called LEICA, uses E. coli as the host bacterium and relies on its growth rate to reflect human enzyme performance.
Kavraki's interdisciplinary research in robotics and biomedicine has been recognized for its impact on manufacturing, space exploration, and medicine. Her work bridges theory and application, with contributions to novel robot motion planning, personalized cancer treatments, and drug discovery.
A new AI technique has been developed to identify promising antiviral compounds against human enterovirus 71 using only a modest amount of experimental data. The method, which combines traditional laboratory methods with machine learning algorithms, was able to predict reliable antiviral activity in five out of eight tested compounds.
The Virginia Tech Helmet Lab has released an updated set of equestrian ratings that considers impact scenarios with horizontal velocity, typically occurring in racing and cross-country events. The new ratings aim to inform consumer decisions about helmet purchasing by reflecting concussion risk associated with each model.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.
Researchers at Princeton University developed a 'metabot' material that can expand, assume new shapes, move, and respond to electromagnetic commands. The metamaterial's complex behavior is enabled by chirality, allowing it to defy typical physical object rules.
Researchers at Brown University suggest that gold nanoparticles could one day be used to restore vision in people with macular degeneration and other retinal disorders. The nanoparticles, when injected into the retina, can stimulate the visual system and restore vision in mice with retinal disorders.
Researchers at MIT engineered bacteria to produce unique wavelengths of light that can be detected using hyperspectral cameras. This technology could enable the development of bacterial sensors for agricultural applications, such as monitoring crop health and detecting pollutants.
A team of researchers from Télécom Paris and Politecnico di Milano has developed a system of optical micro-antennas integrated into a programmable photonic chip, which can adapt in real time to restore chaotic signals. This innovation paves the way for chaos-based encryption for secure high-speed communication in hostile environments.
Researchers at MIT successfully triggered a key enzyme in starfish egg cells using different patterns of light, prompting predictable movements and contractions. The study provides a new optical tool for controlling cell shape in its earliest developmental stages.