Articles tagged with Bioengineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at MIT successfully triggered a key enzyme in starfish egg cells using different patterns of light, prompting predictable movements and contractions. The study provides a new optical tool for controlling cell shape in its earliest developmental stages.
A research group at Peking University discovered dopamine's role in regulating Tau's function through a novel chemoproteomic strategy. This finding deepens our understanding of dopamine's physiological and pathological roles in the human brain.
Researchers identified a Y chromosome-linked gene, UTY, as a key driver of valve calcification in males. In females, fibrotic tissue formation stiffens the valve, leading to different disease progression. The study highlights the importance of sex-based mechanisms in heart valve disease
Researchers at Osaka Metropolitan University developed an engineered yeast that can produce record-high yields of D-lactic acid from methanol, a key compound used in biodegradable plastics and pharmaceuticals. The optimized yeast strain achieves a 1.5-fold boost in production compared to other methanol-based methods.
MIT engineers have developed a way to grow artificial muscles that twitch and flex in multiple coordinated directions. This breakthrough allows for the creation of soft, wiggly robots with enhanced flexibility and range of motion.
Richard Willson, a University of Houston professor, has been elected Fellow of the Royal Society of Chemistry for his contributions to the chemical sciences. He has developed innovative methods to detect viruses and other biological threats using glow-in-the-dark nanoparticles.
Dr. Sarah Du, an associate professor at Florida Atlantic University's College of Engineering and Computer Science, has been selected as a Senior Member of the National Academy of Inventors for her significant contributions to advancing medical technology. Her research focuses on developing point-of-care diagnostic tools and monitoring ...
The University of Illinois researchers have developed organic-material-based nanozymes that can detect histamine in food products with an affordable analytic performance profile. An integrated point-of-use platform allows for rapid detection of agricultural and biological molecules without laboratory equipment.
The University of Texas at Arlington is joining forces with the Texas A&M Engineering Experiment Station to operate a new biomanufacturing center. This partnership will expand UTA's capabilities and provide access to financial support and industry partners, enabling researchers to develop and commercialize production of new bioprod...
Six Lehigh University professors named Senior Members of the National Academy of Inventors, representing diverse fields of chemical engineering, bioengineering, materials science, and electrical computer engineering. They collectively hold over 1200 U.S. patents.
The article reviews additive manufacturing technology for biomedical metals, enabling customized implants with precise internal structures. It highlights the integration of AI and 4D printing, addressing challenges in production costs, regulatory compliance, and post-processing.
Researchers developed a liquid fertilizer replacing unsustainable chemical fertilizers with organic waste, producing up to 100% of nitrogen and 77% of phosphorus. The method also increases phosphorus solubility by adjusting pH levels.
Researchers at the University of Sydney are using Zwitterions to create materials that can prevent blood clots from forming in medical devices and implants. They have successfully created a zwitterionic coating that repels water beyond the material's boundaries.
A new sponge-like implant helps guide a treatment that slows or stops a degenerative condition similar to multiple sclerosis. The implant attracted diseased immune cells, enabling researchers to study and target them with a nanoparticle-based treatment, which prevented mice from developing symptoms such as paralysis if administered early.
Researchers have developed a 'gut-on-chip' model that replicates intestinal inflammation and predicts response to immunotherapy in melanoma patients. The device differentiates between major intestinal populations and reproduces realistic environments.
Researchers from Aalto University have created a synthetic surface inspired by lotus leaves and found that plastronic waves travel along the surface at speeds up to 45 times faster than capillary waves. The discovery could lead to new applications in biotechnology, materials science, and pharmaceuticals.
Lydia Kavraki was elected to the National Academy of Engineering for her groundbreaking contributions to robotics, biomedicine, and artificial intelligence. Her work has revolutionized motion-planning algorithms and enabled robots to collaborate with humans safely.
A team of researchers at Duke University has developed a novel AI-based platform that can design and match small peptides with complex proteins, previously considered unreachable. The PepPrCLIP platform utilizes generative large language models to create peptide guide proteins and an algorithm framework to screen and test the peptides.
Researchers have uncovered how soybean varieties respond to different types of nematode infections, revealing new insights into plant defense mechanisms. The study found that resistant plants activate genes involved in immune responses, while susceptible plants fail to do so, making them vulnerable to attack.
Four Case School of Engineering faculty members, A. Bolu Ajiboye, Christine Duval, Burcu Gurkan, and Steve Majerus, received the Presidential Early Career Award for Scientists and Engineers from the US government. The award recognizes their exceptional talent, dedication, and impact in their respective research fields.
Zebrafish have pineal gland photoreceptors that detect color using parapinopsin 1 (PP1) protein. Two genes, Sagb and Arr3a, play a crucial role in the inactivation of PP1 based on light intensity, with Sagb taking over at higher intensities.
Lehigh University bioengineering researcher Tomas Gonzalez-Fernandez is exploring how combining CRISPR with biomaterials can improve gene editing's safety and efficacy for therapeutic use. His NSF CAREER award-funded research aims to develop more targeted and controlled therapies for genetic diseases.
Professor Yu Xinge, a leading digital health expert, has been awarded the 3rd Zhong Nanshan Youth Science and Technology Innovation Award for his groundbreaking research on bio-integrated electronics. His wearable products aim to monitor health conditions and improve treatment efficiency and accuracy.
The study reveals that directional connections propagate signals in a downstream flow, leading to more complex activity patterns. Mathematical models also suggest that modularity and connectivity interact to foster dynamical complexity.
Researchers at Princeton University discovered that certain bacteria can reduce a plant's immune activity, allowing its roots to grow longer. The study identified an enzyme produced by one of these bacteria as the key factor in this process, which could have implications for understanding microbiome interactions with host immune systems.
MIT researchers developed a biosensing technique that eliminates the need for wires, using tiny wireless antennas with light detection to measure electrical signals from cells. The devices can capture scattered light with an optical microscope and measure signals with micrometer spatial resolution.
Researchers created skin-like replicas using Ecoflex, a type of silicone rubber, to evaluate risks of bacterial infections from intravenous catheters. The study found that the replicas could replicate human skin roughness and elasticity, showing promise for implementing infection control measures.
Researchers at Tohoku University developed lab-grown neurons that form complex networks resembling animal nervous systems. These networks exhibit diverse neuronal ensembles and can be reconfigured through repetitive stimulation, mimicking neural plasticity.
Silvia Blemker, a University of Virginia biomedical engineer, has been elected Fellow of the National Academy of Inventors (NAI) for her work on muscle health. Her patented technology, Image-based Identification of Muscle Abnormalities, uses advanced imaging and analytics to provide detailed insights into muscle health.
The InteReg project aims to create interactive biomaterials that instruct cells to regenerate after brain or spinal cord injuries, potentially treating MS and other neurological disorders. The project, funded by the Carl Zeiss Foundation, brings together experts in biology, chemistry, medicine, and polymer research.
A study by Politecnico di Milano reveals districts most at risk of cardiovascular emergencies during heat waves in Milan. The research found that 23% of the city's population in 18 vulnerable districts face a 22% increased risk, while 20 low-vulnerability districts show no significant increase.
The US Department of Defense has awarded East Tennessee State University's Research Corporation over $900,000 to create a biomanufacturing facility that turns waste streams into valuable products. The project aims to bolster domestic bioindustrial manufacturing and advance sustainable manufacturing goals in Northeast Tennessee.
Scientists at the Swiss Federal Laboratories for Materials Science and Technology have successfully created luminous wood by combining fungal threads with hardwood. The process involves a two-stage enzymatic reaction that stimulates the production of luciferin, emitting green light from the treated wood.
The event brings together leading minds in engineering, oncology, and global health to foster collaboration and recognize achievements within CITEC's community. Groundbreaking research and novel point-of-care solutions aimed at transforming cancer detection and treatment worldwide were showcased during the gathering.
Researchers have developed a new method for designing large artificial proteins with high accuracy, utilizing AI-based software Alphafold2. The approach combines accurate structure prediction with optimization techniques, allowing for the creation of proteins with tailored properties, such as precise binding and stability.
A global team, including Lehigh University researcher Xuanhong Cheng, is exploring molecular- and cellular-level changes in muscle tissue that could lead to better diagnostic tools and therapeutic options for CFS and long COVID. The team aims to develop noninvasive diagnostic tools using electrical signatures.
A $6 million grant from the California Institute for Regenerative Medicine is driving research into a new treatment for dry age-related macular degeneration, a leading cause of blindness in older adults. The therapy aims to halt or reverse disease progression using stem cell-derived healthy retinal pigment epithelium cells.
Researchers at Kyushu University develop a novel technique for building complex 3D microfluidic networks using plant roots and fungal hyphae in silica nanoparticles. This bio-inspired method enables the creation of intricate biological structures, opening new opportunities for research in plant and fungal biology.
Dr. Parag Chitnis at George Mason University leads a multi-disciplinary team researching wearable ultrasound systems for tendon injury prevention and joint assessment.
Researchers created tiny lab-grown models of human immune systems to study immune function in cancer and predict disease treatment response. The miniature models support longer cell function, allowing processes like antibody formation to occur similar to the human body.
Researchers found that facemask connections affect helmet performance, leading to increased impact forces. The team developed a novel testing method to measure facemask strength without destruction.
A new study by MIT engineers reveals that exercise can stimulate nerve growth, with neurons growing four times farther in the presence of myokines released during muscle contractions. Physical effects of exercise, such as repeated stretching and pulling, also promote nerve growth, challenging previous biochemical-only theories.
Scientists have designed bioluminescent proteins that can produce multiple colors of light for real-time imaging in cellular and animal models. These proteins are small, efficient, highly stable and can be used for non-invasive bioimaging, diagnostics, drug discovery and more.
Researchers from Osaka Metropolitan University have discovered a combination of green algae and yeast that enhances wastewater treatment efficiency. The mixture boosts the growth environment, uptake of ammonium and phosphate ions, making it an effective solution for wastewater treatment facilities.
MIT researchers developed a theoretical foundation for methods to aggregate genes into related groups, enabling the efficient learning of underlying cause-and-effect relationships. They achieve this using only observational data, potentially paving the way for targeted treatments.
Researchers from the IBB-UAB have developed novel nanoparticles capable of trapping and neutralizing large quantities of SARS-CoV2 virus particles. These nanostructures could be used to manufacture antiviral materials such as wastewater and air filters, and develop new tests for early Covid-19 detection.
A team of researchers, including Binghamton University's Ahyeon Koh, is working on an innovative project to treat inflammatory bowel diseases like Crohn's and ulcerative colitis. The goal is to create a 'cell factory' in the body that can produce pharmaceuticals to alleviate symptoms.
A team of biomedical engineers from the University of Melbourne has developed a groundbreaking 3D printing system that can fabricate complex human tissues in just seconds. This technology significantly improves the potential to predict and develop new pharmaceutical therapies, reducing the need for animal testing.
University of Texas at Dallas researchers have designed a 3D-printed femur that can help doctors prepare for surgeries and develop treatments for bone tumors. The bone replica is made of polylactic acid, a bio-based polymer, and performed as well as a human femur in biomechanical tests.
Researchers at the University of Oxford have developed a miniature, soft lithium-ion battery with features like high capacity, biocompatibility, and biodegradability. The battery was used to power small devices in animal models and demonstrated promising results for wireless and biodegradable devices in clinical medicine.
Researchers demonstrate the first cross-chiral exponential amplification of an RNA enzyme, potentially leading to the development of cross-chiral therapeutics and biotechnologies. The discovery suggests that a bioengineer can create a new form of biochemical evolution by using both left- and right-handed molecules.
The Center for Genomic Diagnostics at the University of Illinois will develop sensitive and rapid biosensors to detect African swine fever virus. The grant aims to improve on-farm detection and surveillance, providing timely control measures.
Researchers have discovered a protein shell in diatoms that enables efficient CO2 fixation, with implications for bioengineering approaches to combat climate change. The discovery reveals how diatoms convert CO2 into nutrients through photosynthesis, with potential applications for improving carbon capture from the atmosphere.
A groundbreaking study has demonstrated the clinical success of a new nanoparticle-based, laser-guided therapy for prostate cancer treatment. The therapy successfully eliminated cancerous cells in 73% of patients after 12 months while preserving key functions and side effects.
Studies show that the cerebellum is critical for forming stable memories for sensorimotor skills, largely independent of short-term memory systems. Researchers found that longer time intervals between trials increased reliance on impaired long-term memory.
Researchers at MIT have developed a new expansion technique to image nanoscale structures inside cells using conventional light microscopes. The method, which expands tissue 20-fold in a single step, allows for high-resolution imaging of organelles and protein clusters.
Researchers at UC San Diego developed a fluorescent biosensor to observe PKC activity in real time and 3D space. The study revealed designated signaling territories where different types of PKC are active, shedding light on their critical role in human disease.
Researchers developed an octopus-inspired adhesive with elastic, curved stalk and membrane that adheres to multiple surfaces in wet environments. The adhesive demonstrated strong attachment to complex objects and could be rapidly attached and released.
Researchers at Lehigh University are developing predictive models for gene editing with CRISPR to improve outcomes and expand medical applications. The team is using AI and advanced computer models to simulate the effects of altering a single gene on the entire genome, enabling them to predict and avoid unintended consequences.
Researchers have made breakthroughs in creating nanoparticles that can modify the immune system to accept transplanted organs without compromising it. This new approach has potential implications for treating diabetes, cell therapy, and autoimmune disorders, offering hope for patients who currently face rejection.