Articles tagged with Bioengineering
Researchers have developed bioelectronic hydrogels made from conducting polymer microparticles that can be injected into the body or used as injectable therapies. The material has the potential to emulate properties of the body and leverage its functions for more sophisticated ways of doing it.
Researchers developed a generative AI model, BIGE, to generate optimal motions for athletes to avoid injuries and aid in rehabilitation. The model can produce realistic videos of motions that athletes can mimic during training or execute while injured.
Scientists have characterized lipid nanoparticles' internal shape and structure, which correlates with how well they deliver therapeutic cargo. The research provides a blueprint for engineering more effective RNA therapies by matching LNP designs to specific therapies and tissues.
The winners of the Applied Microbiology International Horizon Awards 2025 have been recognized for their groundbreaking contributions to global challenges through applied microbiology. The awards celebrate excellence across various domains, including drug discovery and sustainable agriculture.
Researchers used a new high-resolution mapping technique to find small 3D loops connecting regulatory elements and genes that persist during cell division. These loops strengthen when chromosomes become more compact, potentially helping cells 'remember' interactions from one cell cycle to the next.
Researchers developed a method to trigger magnetic jamming in materials using wireless magnetic fields, enabling reversible and programmable clumping. This technique allows for the creation of structures that can assemble, stiffen, relax, or break apart under magnetic control.
A recent study published in Integrative and Comparative Biology found that bonnethead sharks' skin undergoes significant changes as they mature, with younger sharks having fewer ridges on their denticles. These changes likely improve swimming performance and protect the skin from predators or injuries.
Researchers developed a technology to detach cells from surfaces on demand, reducing waste and improving workflow in industrial processes. The system uses electrochemically generated bubbles to separate cells without damaging them, paving the way for more efficient CO2 absorption and lifesaving cell therapies.
New research from the Stowers Institute for Medical Research reveals planarian stem cells ignore their nearest neighbors and respond to signals further away in the body. This discovery may help explain the flatworm's extraordinary ability to regenerate and offer clues for developing new ways to replace or repair tissues in humans.
Researchers at MIT have developed a new system that allows for precise control over the expression of synthetic genes in cells. The DIAL system uses a promoter editing mechanism to establish desired protein levels, which can be edited after delivery. This technology has the potential to improve gene therapy and cell reprogramming appli...
Researchers developed a new approach to overcome treatment resistance in aggressive cancers by activating macrophages, a type of immune cell abundant in advanced tumors. The custom anti-αvβ3 antibody triggers powerful anti-tumor responses and is highly selective, making it a potentially safer alternative.
Nanoparticle-mediated cancer therapeutics offer improved targeting and reduced toxicity through passive and active mechanisms. This enhances therapeutic results while tackling drug resistance and boosting specificity.
Dr. Quentin Sanders and his team are developing customized prosthetic limbs for active children with lower extremity amputation through 'Fused Filament Fabrication'. Their research aims to identify factors influencing child participation in physical activity and predict demands on prostheses.
Researchers at UCSB have created an algae-based gel as a platform for studying mammary epithelial cells, which can transform into cancer cells. The gel supports the development of normal mammary gland tissue and can be modified to direct cell growth, offering new insights into how cancer develops.
A new test delivers results in under an hour without specialized lab equipment, enabling 'screen-and-treat' strategies to save countless lives. The portable, battery-operated device is projected to cost less than $8 each, making it ideal for low-resource settings.
A new study from the Hebrew University of Jerusalem suggests that the stability of alpha amino acid backbones led to their selection as the foundation for proteins. The research proposes an assembly-driven model for the origins of life, offering fresh insight into how chemistry shaped biology.
Researchers identified mucins that defend against Salmonella and other bacteria causing diarrhea. Synthetic versions of these mucins could help prevent or treat illness in soldiers or travelers. The study suggests a low-cost solution to a major global health challenge.
A new study finds that over 50% of small-molecule drug patents this century are connected to NIH-backed research that would likely be cut under a 40% budget reduction. This highlights the significant impact of federally funded research on the development of life-changing medicines.
A new high-throughput screening approach has enhanced CRISPR genome-editing efficiency by identifying promising CAST variants. The method allows for rapid optimization of these candidates, uncovering mechanistic insights that can inform further engineering and potential clinical use.
A wearable device called a-Heal optimizes each stage of the wound healing process using AI and bioelectronics, delivering medication or an electric field for personalized treatment. Initial preclinical results show the device speeds up the healing process by 25% compared to standard care.
A new study reveals a way to produce short-chain volatile fatty acids (VFA) at lower cost by adding hydrogen peroxide to sewage, which can then be reclaimed for use in manufacturing and agricultural processes. Light exposure further enhances the efficiency of this process.
Two projects funded by federal grants use AI to design proteins for industrial applications, such as producing acrylates in paints. UC Davis will also expand its student training program in protein design to bring hands-on research opportunities to thousands of students nationwide.
Researchers at Graz University of Technology created a highly detailed digital twin of the A549 lung cancer cell line, paving the way for individualized cancer treatment. The model simulates calcium dynamics and electrical voltages, allowing for testing of drugs and personalized treatment strategies.
Researchers at MIT have developed a new approach to gene editing that reduces errors by up to 90%, making it a safer alternative for treating genetic diseases. The technique uses modified versions of the Cas9 enzyme to target specific DNA sequences, reducing off-target effects and increasing precision.
The team will study neurons within a brain organoid, a millimeter-sized, three-dimensional structure grown in the lab from adult stem cells, to design smarter and more sustainable artificial intelligence. They aim to replicate complex computations that occur in the human brain to improve AI efficiency.
A new review in Microbial Biotechnology highlights microbes as allies in various industries, from food fermentation to biofuels. Films such as French Kiss and The Martian showcase microbes as positive forces, challenging the traditional villain stereotype.
Scientists have achieved a major breakthrough by 3D bioprinting miniature placentas, which can accurately replicate the human placenta. This technology has the potential to transform pregnancy research by allowing for the study of serious complications like preeclampsia.
Researchers at UC Davis develop new technologies for plant-based biomanufacturing, addressing resource constraints and sustainability. The project aims to create a powerful technology for producing biomolecules and materials, focusing on low-cost infrastructure, novel bioproduction platforms and efficient processing.
Researchers from Korea University mapped the evolutionary trajectory of meningiomas at single-cell resolution, revealing profound shifts in proliferative programs and tumor–immune interactions. The study identified COL6A3 as a central player driving recurrence and treatment resistance.
Researchers at NUS have developed a bioengineering approach to keep human lymph node tissue alive and functioning outside the body for several days. The method involves embedding thin slices of lymph node tissue in a soft gel that mimics the body's natural environment, allowing for detailed studies of immune cell behavior.
Researchers create peptide hydrogel that controls drug release, improving treatment adherence and efficacy for conditions like tuberculosis and diabetes. The SABER platform uses reversible chemical bonds to slow down drug release, offering a promising solution for precise delivery.
Graz researchers investigate homocysteine's impact on the aorta, finding elevated levels lead to stiffer and less elastic vessels. This discovery contributes to understanding of cardiovascular diseases like atherosclerosis.
A new hydrogel has been developed to combat vaginal changes caused by menopause, offering a hormone-free alternative for treatment. The study found that the hydrogel improved vaginal tissue thickness and reduced inflammation, providing potential relief from symptoms such as dryness and pain.
Researchers at UMC Utrecht developed a new AI-powered printer called GRACE that can print implantable tissues with improved cell survival and functionality. The printer uses computer vision and laser-based imaging to design and print complex structures, including blood vessels and cartilage layers.
Scientists developed hollow microspheres with adjustable pore size, adhesion, and lubricity properties using mucus and polydopamine. These spheres can be used as drug delivery agents and may prevent tissue damage or provide a protective coating.
Engineered cell lines are prone to misidentification, threatening scientific discoveries and intellectual property. Researchers at UT Dallas have developed a novel method to embed unique genetic identifiers, eliminating identification errors and safeguarding innovations with tamper-proof genomic tags.
Researchers at Harvard SEAS have developed a gentler, more sustainable way to break down keratins and turn leftover wool and feathers into useful products. The process uses concentrated lithium bromide to create an environment favorable for spontaneous protein unfolding.
Researchers at Ohio State University discovered that adding an electrical jolt to fermentation increases the yield and speed of platform chemicals from industrial food waste. Combining two bacterial species also enhances targeted chemical production and produces hydrogen gas as a byproduct, reducing waste and greenhouse gas emissions.
Scientists have developed a new computational method to build the first 4D lipid map of a vertebrate embryo, capturing how lipid distributions change over time. The atlas reveals organized patterns of lipids that match anatomical structures, suggesting key roles in shaping organ function and identity.
The system uses magnetoelectric power-transfer technology to deliver precise electrical stimulation to organs like the heart and spinal cord. The more devices in the network, the more efficient it is, offering a less invasive alternative to traditional implantable medical devices. This technology has potential for treating conditions s...
Researchers developed novel sweat sensors that mimic the microtexture of rose petals, enhancing stability, performance, and comfort. The sensors demonstrate a self-cleaning effect, reducing skin irritation and improving user comfort, making them suitable for wearable devices like smartwatches.
A team of researchers has developed a new method to produce sturdy and reusable bioplastics from domestic raw materials, reducing reliance on petroleum-based chemicals. The bioplastics, known as polyhydroxyalkanoates (PHAs), have similar levels of toughness and malleability to traditional plastics, but are infinitely recyclable.
Researchers from Seoul National University of Science & Technology developed a smart adhesive system based on starfish for temporary and switchable underwater adhesion. The system exhibits high adhesion hysteresis, automatic release based on outside stimuli, and quick detachment by pneumatic actuation.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
Researchers from Japan and USA discover midline tissues use formation control to grow harmoniously, with the notochord leading elongation and adjacent tissues migrating together through fibroblast growth factor gradients and cell adhesion. Computer simulations confirm this mechanism is essential for synchronized tissue development.
Angel Martí, David Sarlah, and Haotian Wang have been honored with national American Chemical Society awards for their outstanding work in chemistry. The ACS awards recognize individuals who not only advance the field but also inspire students from underrepresented backgrounds to pursue careers in chemical sciences.
Researchers have developed a data-driven way to fit prosthetic legs that could lead to better fitting prosthetics in less time and at a lower cost. The new technology generates basic design recommendations instantly and has been shown to be as comfortable on average as those created by highly skilled prosthetists.
A wearable robot has been upgraded to provide personalized assistance to ALS and stroke patients. The device uses machine learning and a physics-based model to adapt to an individual user's movements, offering more nuanced help with daily tasks.
Glaucoma is a leading cause of vision loss, with over 7.7 million people globally affected in 2020. The new microstent reduces excessive fluid buildup and intraocular pressure, supporting the eye's natural space and improving treatment efficacy. Its durable nickel-titanium alloy enables long-term safety and functionality.
Researchers have created a wearable system that combines drug delivery, electrical stimulation, and continuous monitoring to treat diabetic foot ulcers. The microneedle platform anchors securely into the skin and adjusts therapy in real-time to prevent severe tissue damage.
A new study demonstrates the potential to produce cellular spheroids from clinically relevant embryonic stem cells to generate scaffold-free chondrogenic or osteochondrogenic graft tissues. The researchers successfully cultured ES-MSC cellular spheroids, which matured into neocartilage tissues expressing cartilage-associated genes.
Researchers at North Carolina State University have developed a controlled evolution technique that dramatically increases plasmid DNA (pDNA) production in E. coli bacteria. This breakthrough could significantly reduce the cost of gene therapies and expedite research, making pDNA resources more accessible.
The book provides a roadmap for sustainable and ethical leadership in engineering management, focusing on ESG reporting, CSR integration, and industry-specific insights. It offers practical tools and strategies for professionals to make informed decisions that reduce ecological impact and improve resource efficiency.
Newly developed DNA nanostructures form flexible, fluid, and stimuli-responsive condensates without chemical cross-linking. These findings pave the way for adaptive soft materials with potential applications in drug delivery, artificial organelles, and bioengineering platforms.
A team of researchers found that co-cultivating common bean plants with fragrant bush basil increases the expression of a key gene in plant defense mechanisms, reducing egg-laying activity of agricultural pests. This natural pest control method uses VOCs emitted by bush basil to attract beneficial insects and trigger plant defenses.
Researchers from Trinity College Dublin develop a method to harness structural colour using microfabrication technique, enabling ultra-sensitive materials for environmental sensing and biomedical diagnostics. The breakthrough also paves the way for next-generation medical sensors that can track biochemical changes in real-time.
The journal is seeking high-quality submissions that explore the potential of voice and speech analysis in diverse medical applications. Submissions focus on acoustic and voice analysis techniques, voice or vocal phenotyping, and vocal biomarkers in health and medicine.
A new silicone patch with star-shaped microneedles, called the ExoPatch, distinguishes melanoma from healthy skin in mice, capturing cancer biomarkers from exosomes. The test shows promise for early detection of the most aggressive form of skin cancer without a biopsy or blood draw.
Researchers at Washington University in St. Louis have developed a new type of bioplastic, called LEAFF, which is strong, biodegradable, and printable. This innovation uses cellulose nanofibers to address the limitations of current bioplastics and has potential applications for sustainable packaging.
A new AI model called RiboNN predicts translation efficiency of mRNA sequences, accelerating the development of mRNA therapeutics. The tool helps predict how much protein cells will produce, minimizing trial-and-error experimentation.