Articles tagged with Bioengineering
Researchers discovered a unique nanostructure in blue shark skin that produces their iconic blue coloration, which also suggests a potential capacity for color change. Tiny changes in guanine crystal spacing can alter the shark's body color to suit its environment.
A research team led by Professor Joongoo Lee successfully expanded ribosome range to produce ring-shaped backbones in proteins. This breakthrough could open doors to novel therapeutics and advanced biomaterials.
Researchers have developed novel three-dimensional liver organoids using bile acids, which retain hepatocyte-like features and can be sustained in long-term cultures. These organoids demonstrate a unique gene expression profile similar to fetal hepatocytes and support replication of hepatitis viruses.
Researchers developed an AI-informed method for rapid protein evolution, integrating structural and evolutionary constraints. The approach, AiCE, outperforms traditional methods in predicting high-fitness mutations, enabling efficient protein redesign and applications in precision medicine.
A new computational method combines 4D flow MRI, CFD, and data assimilation to estimate blood flow in brain aneurysms with greater accuracy and efficiency. The approach focuses on the aneurysm region, reducing computational cost while improving flow estimation.
Chihtong Lee's research on retractor blade geometry explores how small design changes can improve patient recovery after spinal surgery. Her work, conducted in collaboration with Baylor College of Medicine, showed that blades with soft, biocompatible coatings significantly reduced tissue stress and postoperative complications.
Researchers at the University of Sydney developed a biological 'artificial intelligence' system called PROTEUS, which can accelerate cycles of evolution and natural selection to create molecules with new functions in weeks. The system has potential applications in finding new medicines and improving gene editing technology like CRISPR.
Scientists have developed a new tool named scICE to tackle the stability problem in single-cell RNA sequencing data. The tool provides a way to validate clustering outcomes mathematically, ensuring higher confidence in conclusions drawn from single-cell data.
A new hydrogel-based platform has been developed to preserve live patient-derived tumor tissues in the lab, enabling more accurate testing of cancer treatments. The approach, which uses customizable bioengineered hydrogels, has been shown to retain key features of the original tumor environment.
Researchers from Pusan National University have developed engineered bacterial vesicles that use a novel surface-displaying protein to selectively target and eliminate E. coli and S. aureus bacteria. These vesicles, derived from lactic acid bacteria, offer a promising alternative to conventional antibiotics.
Researchers developed a miniature 'leukemia-on-a-chip' device that recreates human bone marrow and immune system to predict cancer immunotherapy success. The device enables real-time observation of how immunotherapy drugs interact with cancer cells in an environment closely mimicking the human body.
Researchers at Iowa State University developed a new internal barrel design for the 'gene gun' technology, improving its efficiency by up to 50 times. The Flow Guiding Barrel reduces particle loss and uneven distribution, enabling more consistent and reliable genetic material delivery into plant cells.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
Researchers successfully engineered oilseed crop Camelina to produce high levels of astaxanthin, a valuable red antioxidant used to color farmed salmon and shrimp. The plant-derived pathway proved more efficient and cleaner than earlier bacterial methods, reaching over 47 micrograms per gram of seed.
Researchers from Binghamton University confirm the long-held 'urban myth' that saltwater dries out skin, increasing tissue stiffness and stress. A simple solution to alleviate tightness is taking a shower after coming out of the ocean.
Researchers have developed a method to transform polyethylene terephthalate (PET) plastic waste into paracetamol using genetically reprogrammed E. coli bacteria. The new process creates virtually no carbon emissions and can be completed in under 24 hours.
Bio Integration has a new institutional partner, University of South China's Institute of Sports Medicine, Fudan University, to support its interdisciplinary research in biomaterials, regenerative medicine, and translational healthcare. Professor Chaozong Liu joins as Co-Editor-in-Chief to shape the journal's editorial direction.
International Journal of Extreme Manufacturing (IJEM) achieves a new Impact Factor of 21.3, surpassing 20 for the first time and maintaining its position as top journal in the field. IJEM has attracted submissions from 853 institutions in 81 countries.
Bioengineering researchers at Harvard John A. Paulson School of Engineering and Applied Sciences developed a soft, thin, stretchable bioelectronic device that can be implanted into a tadpole embryo's neural plate, recording electrical activity from single brain cells with millisecond precision.
Scientists replace toxic additives in hydrogels with D-sorbitol, a safe sugar alternative found in chewing gum, to create bioelectronic devices that are soft, safe, and integrated with natural tissue. The new material has increased biocompatibility and improved electronic performance.
The Terasaki Institute and California State University, Northridge (CSUN) have launched a new collaboration initiative that brings advanced hands-on laboratory experience to CSUN Biology graduate students. Participating students will work alongside leading scientists on projects in various fields of biomedical research.
A new microscope, QIScope, significantly improves bioluminescence imaging by detecting extremely low levels of light. It offers higher sensitivity, improved resolution, and a wider field of view, allowing researchers to track subtle changes in living cells over extended periods.
Researchers have developed a new tool using quartz crystal microbalance with dissipation monitoring to study DNA-lipid interactions. The technique revealed insights into the attachment and integration of DNA nanostructures with lipid membranes, influencing cellular functions such as drug delivery and treatment precision.
A study by University of Fukui researchers reveals that two adjacent gene pairs in Neurospora crassa regulate antiviral response and symptom induction via RNA editing. The findings indicate that the modification of master transcription factor genes is crucial for controlling fungal antiviral responses.
A joint research team from POSTECH and Hanyang University developed a personalized stimulation control mechanism using evoked compound action potential feedback mechanisms to treat urinary disorders. This technology enables precise adjustment of tibial nerve stimulation in real-time, based on individual nerve responses, improving patie...
Researchers from Florida Atlantic University and the German Electron Synchrotron mapped the internal structure of blacktip sharks in unprecedented detail, discovering a microscopic 'sharkitecture' composed of densely packed collagen and bioapatite. This intricate structure gives cartilage surprising strength while allowing flexibility.
Antonios Mikos, a leading expert in biomaterials and tissue engineering, has been elected to the European Academy of Sciences. He is recognized for his groundbreaking work in regenerative medicine, controlled drug delivery, gene therapy, and disease modeling.
Researchers at the University of Arizona have developed a longer-lasting, 3D-printed wearable capable of providing comprehensive physiological data. The device continuously tracks and logs water vapor and skin emissions to monitor dehydration, metabolic shifts, and stress levels.
Researchers at UC San Diego's Scripps Institution of Oceanography developed a gel called SNAP-X that releases chemical cues encouraging coral larvae settlement. In laboratory tests, SNAP-X increased coral settlement by up to 20 times compared to untreated surfaces, offering a promising solution for coral reef restoration efforts.
Researchers at KAUST created an electrochemical sensor that detects vitamin D deficiency using MXene-antibody hybrid biosensor device. The sensor has a detection limit of 1 picogram per milliliter, making it suitable for point-of-care testing in remote healthcare centers.
A new AI model can predict protein location in human cells with high accuracy, enabling faster diagnosis of diseases like Alzheimer's and cancer. By combining protein sequence analysis with computer vision, the model can pinpoint proteins' locations at the single-cell level.
Researchers developed a rapid fluorochromic sensing method for detecting tertiary amines and opioids, enabling faster and more accurate analysis. The new approach uses photoinduced charge-transfer complexes to differentiate between structurally similar amines based on their substituents and molecular flexibility.
Engineers at Princeton University and Georgia Institute of Technology have created a method to reinforce structures without creating new weaknesses. The approach uses microstructures designed to protect against multiple loads, allowing designers to counter various stresses simultaneously.
A new AI technique has been developed to identify promising antiviral compounds against human enterovirus 71 using only a modest amount of experimental data. The method, which combines traditional laboratory methods with machine learning algorithms, was able to predict reliable antiviral activity in five out of eight tested compounds.
Researchers at UC San Diego create a simple approach to rapidly check on human gene changes by turning everyday bacteria into living test tubes. This technique, called LEICA, uses E. coli as the host bacterium and relies on its growth rate to reflect human enzyme performance.
Kavraki's interdisciplinary research in robotics and biomedicine has been recognized for its impact on manufacturing, space exploration, and medicine. Her work bridges theory and application, with contributions to novel robot motion planning, personalized cancer treatments, and drug discovery.
The Virginia Tech Helmet Lab has released an updated set of equestrian ratings that considers impact scenarios with horizontal velocity, typically occurring in racing and cross-country events. The new ratings aim to inform consumer decisions about helmet purchasing by reflecting concussion risk associated with each model.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.
Researchers at Princeton University developed a 'metabot' material that can expand, assume new shapes, move, and respond to electromagnetic commands. The metamaterial's complex behavior is enabled by chirality, allowing it to defy typical physical object rules.
Researchers at Brown University suggest that gold nanoparticles could one day be used to restore vision in people with macular degeneration and other retinal disorders. The nanoparticles, when injected into the retina, can stimulate the visual system and restore vision in mice with retinal disorders.
Researchers at MIT engineered bacteria to produce unique wavelengths of light that can be detected using hyperspectral cameras. This technology could enable the development of bacterial sensors for agricultural applications, such as monitoring crop health and detecting pollutants.
A team of researchers from Télécom Paris and Politecnico di Milano has developed a system of optical micro-antennas integrated into a programmable photonic chip, which can adapt in real time to restore chaotic signals. This innovation paves the way for chaos-based encryption for secure high-speed communication in hostile environments.
Researchers at MIT successfully triggered a key enzyme in starfish egg cells using different patterns of light, prompting predictable movements and contractions. The study provides a new optical tool for controlling cell shape in its earliest developmental stages.
A research group at Peking University discovered dopamine's role in regulating Tau's function through a novel chemoproteomic strategy. This finding deepens our understanding of dopamine's physiological and pathological roles in the human brain.
Researchers at Osaka Metropolitan University developed an engineered yeast that can produce record-high yields of D-lactic acid from methanol, a key compound used in biodegradable plastics and pharmaceuticals. The optimized yeast strain achieves a 1.5-fold boost in production compared to other methanol-based methods.
Researchers identified a Y chromosome-linked gene, UTY, as a key driver of valve calcification in males. In females, fibrotic tissue formation stiffens the valve, leading to different disease progression. The study highlights the importance of sex-based mechanisms in heart valve disease
MIT engineers have developed a way to grow artificial muscles that twitch and flex in multiple coordinated directions. This breakthrough allows for the creation of soft, wiggly robots with enhanced flexibility and range of motion.
Dr. Sarah Du, an associate professor at Florida Atlantic University's College of Engineering and Computer Science, has been selected as a Senior Member of the National Academy of Inventors for her significant contributions to advancing medical technology. Her research focuses on developing point-of-care diagnostic tools and monitoring ...
Richard Willson, a University of Houston professor, has been elected Fellow of the Royal Society of Chemistry for his contributions to the chemical sciences. He has developed innovative methods to detect viruses and other biological threats using glow-in-the-dark nanoparticles.
The University of Illinois researchers have developed organic-material-based nanozymes that can detect histamine in food products with an affordable analytic performance profile. An integrated point-of-use platform allows for rapid detection of agricultural and biological molecules without laboratory equipment.
The University of Texas at Arlington is joining forces with the Texas A&M Engineering Experiment Station to operate a new biomanufacturing center. This partnership will expand UTA's capabilities and provide access to financial support and industry partners, enabling researchers to develop and commercialize production of new bioprod...
Six Lehigh University professors named Senior Members of the National Academy of Inventors, representing diverse fields of chemical engineering, bioengineering, materials science, and electrical computer engineering. They collectively hold over 1200 U.S. patents.
The article reviews additive manufacturing technology for biomedical metals, enabling customized implants with precise internal structures. It highlights the integration of AI and 4D printing, addressing challenges in production costs, regulatory compliance, and post-processing.
Researchers developed a liquid fertilizer replacing unsustainable chemical fertilizers with organic waste, producing up to 100% of nitrogen and 77% of phosphorus. The method also increases phosphorus solubility by adjusting pH levels.
Researchers at the University of Sydney are using Zwitterions to create materials that can prevent blood clots from forming in medical devices and implants. They have successfully created a zwitterionic coating that repels water beyond the material's boundaries.
A new sponge-like implant helps guide a treatment that slows or stops a degenerative condition similar to multiple sclerosis. The implant attracted diseased immune cells, enabling researchers to study and target them with a nanoparticle-based treatment, which prevented mice from developing symptoms such as paralysis if administered early.
Researchers have developed a 'gut-on-chip' model that replicates intestinal inflammation and predicts response to immunotherapy in melanoma patients. The device differentiates between major intestinal populations and reproduces realistic environments.
Researchers from Aalto University have created a synthetic surface inspired by lotus leaves and found that plastronic waves travel along the surface at speeds up to 45 times faster than capillary waves. The discovery could lead to new applications in biotechnology, materials science, and pharmaceuticals.
Lydia Kavraki was elected to the National Academy of Engineering for her groundbreaking contributions to robotics, biomedicine, and artificial intelligence. Her work has revolutionized motion-planning algorithms and enabled robots to collaborate with humans safely.
A team of researchers at Duke University has developed a novel AI-based platform that can design and match small peptides with complex proteins, previously considered unreachable. The PepPrCLIP platform utilizes generative large language models to create peptide guide proteins and an algorithm framework to screen and test the peptides.