Articles tagged with Bioengineering
Purdue University researchers developed a portable, paper-based system to detect fecal contamination on commercial fresh produce farms. The system uses loop-mediated isothermal amplification (LAMP) and achieves 100% accurate results within an hour.
A new technology combines femtosecond laser-designed lubricated slippery surfaces with electrostatic interactions to manipulate droplets. This allows for diverse working conditions and functions, including driving droplets on inclined surfaces, manipulating various liquids, and sorting particles.
Researchers at Johns Hopkins Medicine identified a potentially new biological target involving Aplp1, which drives the spread of Parkinson's disease-causing alpha-synuclein. The findings suggest targeting this interaction with drugs could slow Parkinson's disease progression and other neurodegenerative diseases.
Researchers at Carnegie Mellon University have successfully integrated focused ultrasound stimulation into noninvasive BCIs, significantly boosting signal quality and enabling bidirectional brain-computer interfaces. The technology allows individuals to control a cursor or robotic arm using only their thoughts.
A new technology combining holographic acoustic devices with genetic engineering allows precise targeting of affected neurons in the brain, potentially treating neurodegenerative diseases. The technique, AhSonogenetics, uses a noninvasive wearable ultrasound device to alter genetically selected neurons in mice, alleviating Parkinson's-...
Researchers are developing advanced electronic bandages to improve chronic wound monitoring and healing. These 'smart' dressings can sense and respond to changing conditions, providing continuous data on healing and potential complications.
Researchers have developed a novel pipeline to study proteins with no fixed structures, using cell-free protein crystallization techniques. This approach enables fast and convenient analysis of intrinsically disordered proteins, paving the way for new drugs and bioanalytical techniques.
Researchers develop fully human antibodies that can neutralize the alpha-latrotoxin of the European black widow, a neurotoxin causing severe pain and hypertension. The study uses in vitro methods to create recombinant human antibodies, offering a safer treatment alternative with potential cross-reactive properties.
Moffitt's dedicated bioengineering department is revolutionizing cancer research through an interdisciplinary approach. This powerful platform combines engineering, physical sciences, and oncology to understand and treat complex cancer.
Researchers Manu Prakash and Eliott Flaum have discovered a new geometric mechanism in the single-cell organism Lacrymaria olor, enabling it to produce complex morphodynamics through curved-crease origami. The cell's cytoskeletal structure encodes this behavior, which is driven by a singularity that acts as a controller.
A University of Houston researcher has developed a new method to detect cancer using PANORAMA imaging and fluorescent imaging, achieving a 98.7% accuracy rate. The method analyzes the number and cargo of small EVs in patients' blood samples, allowing for early detection and improved treatment efficacy.
Researchers created a prototype of 'living bioelectronics', combining bacteria, sensors, and gel to integrate with living tissue. The device reduced inflammation and improved psoriasis-like symptoms in mice, offering potential for treating various skin conditions and injuries.
The ACCELERATE program aims to enhance educational experiences of HCC students, providing access to resources and opportunities for biomedical research training. Students will participate in extracurricular laboratory modules, immersive research training, and mentorship programs.
Researchers at the University of Houston have identified a subset of T cells called CD8-fit that show high motility and serial killing capabilities in patients with clinical responses. These cells were discovered using a patented approach called TIMING, which evaluates cell behavior and movement to identify potential cancer-killing cells.
Researchers developed adhesive hydrogel coatings that eliminate fibrosis, a common issue with medical implants. The coatings bind devices to tissue and prevent the immune system from attacking them.
A team of visionaries at the Carney Institute developed 3D-printed brain and spinal cord implants, revolutionizing surgical implantations and optical access. Bioluminescence imaging overcomes limitations of traditional fluorescent microscopy, providing unprecedented observation of neural and vascular activity.
Researchers at Aarhus University have developed a three-stage process to convert polyethylene (PE) into biodegradable polyester, addressing the issue of plastic waste. The method utilizes enzymes, microorganisms, and chemical processes to break down PE's strong carbon bonds.
Engineers at the University of California San Diego used a new technique called MUSIC to map out interactions between chromatin and RNA in individual brain cells. The study found that some brain cells age faster and are more prevalent in individuals with Alzheimer's disease, particularly in women.
Scientists studied the nickel-tungsten alloy interface to understand its properties and behavior. The research revealed the formation of intermetallic compounds and diffusion-induced recrystallization regions, which significantly impact the material's mechanical, thermal, and chemical properties.
A study published in Nature Geoscience elucidates the discrepancy between Martian and Earth-based organic matter. Researchers found that photodissociation of carbon dioxide in the atmosphere leads to organic matter with depleted carbon-13 content, pointing to an atmospheric process as the main source.
MIT engineers create technique to image bioluminescent molecules in deep tissue with high resolution, enabling detailed studies of brain cell development and communication. The method uses engineered blood vessels that dilate in response to light, allowing researchers to pinpoint the source of light.
Researchers at the University of Cambridge developed flexible electronic devices that wrap around the spinal cord, recording nerve signals and stimulating limb movement. The devices could lead to treatments for spinal injuries without brain surgery, improving safety for patients.
Researchers created GraSSRep and rhea, tools that outperform current methods for handling repeats and structural variants in metagenomic data. These methods use self-supervised learning and graph neural networks to analyze microbiome data, offering new insights into biological processes and potential applications in antibiotic resistance.
A team of researchers has developed a hemostasis sponge that swiftly staunchs kidney bleeding and facilitates wound recovery. The material uses kidney-derived decellularized extracellular matrix to recreate the kidney's microenvironment, boasting high biocompatibility.
Researchers at the University of Washington have solved a long-standing chemical mystery in organic electrochemical transistors (OECTs), which allow current to flow in devices like implantable biosensors. The study reveals that OECTs turn on via a two-step process, causing a lag, and off through a simpler one-step process.
Researchers at the University of California San Diego developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores from Bacillus subtilis. The material breaks down in compost environments within five months, even without additional microbes.
Scientists from OIST created synthetic droplets to mimic biological processes, finding that pH gradients facilitate Marangoni effect and enabling droplets to detect and migrate towards each other. This study sheds light on the movement of simplest forms of life in primordial soup billions of years ago.
A flexible microdisplay device can track and display neural activity in the brain, allowing neurosurgeons to visualize critical cortical boundaries and guide surgical interventions. The device reduces the need for a buffer zone, enabling more precise removal of harmful tissue.
Scientists have developed mini-colon tissues that can simulate the complex process of tumorigenesis outside the body with high fidelity. These miniature organs mimic the physical structure and cellular diversity of colon tissue, allowing researchers to study colorectal cancer development and test potential therapies.
Researchers have discovered that rice bran-derived nanoparticles exhibit strong anticancer effects, selectively targeting cancer cells while sparing healthy tissue. The nanoparticles reduced tumor growth and inhibited metastatic cell growth in mice models.
Jos Malda receives ERC grant to crack cartilage code and create regenerative treatments. By studying cartilage 'organ-on-a-chip' models and animal cartilages, researchers aim to recreate the intricate internal structure of cartilage.
Researchers at Columbia University developed BeatProfiler, an AI-based software that automates the analysis of heart cell function from video data, significantly speeding up the process and reducing errors. The tool can accurately analyze cardiomyocyte function, outperforming existing tools by being faster and more reliable.
Researchers developed a spring-like device that maximizes muscle contractions to power biohybrid robots. The new flexure design enables predictable and reliable movement, allowing engineers to build muscle-powered robots with increased precision and versatility.
Researchers have discovered a virus that infects the fungus Batrachochytrium dendrobatidis, which causes heart failure in frogs and toads. The virus could be engineered to control the fungal disease and potentially save amphibian species.
A Rice University research project aims to provide new insights into biological fibrillar nanostructures with potential implications for the treatment and diagnosis of Alzheimer’s and Parkinson’s diseases.
The event aims to gather young researchers to discuss opportunities offered by advanced experimental synchrotron techniques available at Sirius. The School will feature lectures, poster sessions, and guided tours, taught by experts in the field.
Researchers have discovered that introducing tardigrade proteins into human cells can slow down molecular processes, making them potential candidates for slowing the aging process. This new study provides evidence that these proteins can be used to induce biostasis in cells, enhancing storage and stability.
The MIT-designed 'architected' reef could dissipate more than 95% of incoming wave energy using a fraction of the material needed, reducing erosion and flooding. The cylindrical structure's unique design leverages turbulence to efficiently break waves, making it a potential solution for coastal protection in various water conditions.
Researchers simultaneously tagged many humpback whales from the same pod to analyze their vocalization and compare individual calls. This study provides new information about whale behavior and communication, crucial for informing future conservation efforts.
A team of UMass Amherst engineers has developed a tissue-like bioelectronic mesh system that can simultaneously measure the electrical signal and physical movement of cells in lab-grown human cardiac tissue. This breakthrough device allows researchers to observe how the heart's mechanical and electrical functions change during developm...
Scientists from UC3M and Johns Hopkins University have developed a computational model that simulates the invasion process of cancer cells based on the characteristics of surrounding tissue and cell junctions. The model allows for predicting tumor evolution in patients by analyzing mechanical properties of the microenvironment.
A multi-institutional team is creating innovative technologies to reduce complications associated with left ventricular assist devices (LVADs), including infection, thrombosis, stroke, and bleeding. The new LVAD will deliver a physiological response to changes in the recipient's activity levels using a 'smart' Maglev drive technology.
Researchers review advances and challenges in applying SLA to evaluate unconventional reservoirs, highlighting its simplicity and convenience. The study proposes modifications to address reservoir heterogeneity and suggests combining SLA with machine learning algorithms for improved accuracy.
Researchers at UVA Health discovered a potential blood test to predict patients with severe COVID-19 who are likely to recover well and those at risk of long-term lung problems. The study found that patients with late-resolving symptoms had fewer immune cells in their blood, correlating with symptom severity.
A team of researchers used CRISPR-Cas9 gene editing to enhance the nutritional profile and flavor of fungi, creating a new source of plant-based food alternatives. The modified fungi produce heme and ergothioneine, which can improve cardiovascular health benefits.
Researchers discover that certain bacteria can evade the immune system by circumventing antibody coating, leading to severe inflammation. The study identifies IgG2 as a key player in this process, providing potential biomarkers and targets for new treatments.
Researchers at the University of Illinois at Urbana-Champaign have created a highly stretchable sensor that can monitor and transmit plant growth information without human intervention. The sensor is resilient to humidity and temperature and can send a wireless signal to a remote monitoring location.
Researchers have introduced a more efficient processing technique that enables scalable fabrication of custom microscale particles for applications in drug delivery, microelectronics, and abrasives. This process, called roll-to-roll CLIP, achieves unprecedented fabrication rates while preserving high resolution.
Researchers at Pohang University of Science & Technology have devised a technique for mass-producing large-area metalenses tailored for use in the ultraviolet region. The breakthrough enables control over optical properties of UV rays, sparking interest in potential advancements for medical devices and wearable technology.
Scientists have developed fUSI technology that enables clinicians to see and map the spinal cord's response to treatments in real-time. This innovation offers improved monitoring of blood flow changes, potentially increasing treatment success rates and optimizing pain relief for patients.
Researchers aim to address LVAD shortcomings, reducing blood damage and clotting risk through innovative designs and coatings. A novel flexible stented blood inlet and slippery hydrophilic coatings will be used to prevent flow stasis and clot formation.
Researchers used mass spectrometry imaging and single-cell metabolomics with deep learning to create 3D molecular maps of the brain, enabling a better understanding of chemical interactions within brain tissue. This breakthrough could help address currently intractable neurological diseases.
Researchers are developing minimally invasive techniques to repair and regenerate tissue in aortic aneurysms using actively targeted, drug-releasing nanoparticles. The team found that rod-shaped particles with high aspect ratios were selectively taken up by diseased endothelial cells, leading to improved therapy outcomes.
A new study has identified a strategy used by early-stage cancer cells to evade the immune system. By turning on the gene SOX17, these cells create an immunosuppressive environment that prevents them from being detected. This gene helps cancer cells ignore immune messages and grow in the presence of an immune system.
Researchers have created a new tool called epidecodeR to analyze epigenetic marks and predict their impact on gene activity. The tool can identify correlations between specific modifications and gene responses in various conditions, including cancer and neurological disorders.
Scientists have developed a new way to alter the DNA of bacterial cells using high-frequency radio waves, outperforming traditional industry techniques. The process shows high efficiency and gentleness, with 91% of E. coli cells taking on the DNA after just three minutes.
A new roadmap has been published by IEEE EMBS, outlining five primary medical challenges that need to be addressed through advanced biomedical engineering approaches. The paper, written by 50 renowned researchers from 34 prestigious universities, aims to guide future research and funding for groundbreaking innovations.
A novel chemotherapy approach uses patient's own cells as Trojan horses to deliver targeted cancer-killing drugs to lung cancer cells. The method has shown promise in reducing tumor size and improving treatment efficacy with minimal collateral damage to healthy tissues.
A team of researchers has developed a bilayer nanofiber membrane hemostat using natural proteins derived from mussels and silkworm cocoons. The hemostatic agent demonstrated rapid acceleration of tissue adhesion and hemostasis in bleeding wounds, preventing the infiltration of water containing infectious agents.
A new method uses digital DNA melting analysis to detect pathogens in blood samples, producing results in under six hours and reducing false positives compared to traditional blood cultures. This technology has the potential to save lives by accurately diagnosing sepsis, a leading cause of death worldwide.