Articles tagged with Bioengineering
The University of Illinois has developed a new nanoscale sensor that can monitor areas 1,000 times smaller than traditional technology, tracking subtle changes in brain chemistry with sub-second resolution. The device takes advantage of silicon-based manufacturing techniques to achieve 100% efficiency and high spatial resolution.
A recent study published in PLOS Biology found that the human brain can segregate direct speech from its echo, allowing for reliable recognition of echoic speech. This neural separation is essential for understanding conversations in noisy environments and is supported by magnetoencephalography recordings.
Researchers found GV1001 decreases BACE and Aβ1-42 levels, reducing neurodegeneration and senescence in 3xTg-AD mice. It also increases survival, telomere length, and telomerase activity, contributing to improved lifespan.
Researchers developed customized adhesive patches using mussel-derived proteins, exhibiting strong underwater adhesion, biocompatibility, and adjustable degradation time. These patches showed successful treatment in animal models, paving the way for personalized medical applications.
A small, wearable ultrasound sticker can monitor organ stiffness and detect subtle changes that signal disease progression. The device has been shown to identify early signs of acute liver failure in rats and may one day help doctors diagnose internal organ failure more effectively.
Researchers at Lawrence Berkeley National Laboratory have developed a new technique to study the breakdown of cellulose by enzymes, revealing that hydrogen bonds in the complex molecule act as obstacles. The approach uses infrared light and operando spectroscopy to provide real-time snapshots of the sample, overcoming past limitations.
Scientists develop a new class of hydrogels that can concentrate proteins within cells, mimicking natural sequestering phenomena. The hydrogels, designed using computers, exhibit similar mechanical properties both inside and outside of cells.
Using optical traps, researchers controlled bacterial aggregation and biofilm development, finding different types of lasers can stimulate or suppress growth. The study opens up possibilities for creating microscopic building materials from bacteria.
A recent study published in Nature Plants reveals that O-glycosylation of the transcription factor SPATULA promotes Arabidopsis style development. The experimental study sheds new light on the mechanisms underlying plant organ symmetry.
A team of researchers from Harvard and Texas developed a soft implantable device with dozens of sensors to record single-neuron activity stably for months. The device uses fluorinated elastomers and is 10,000 times softer than conventional flexible probes.
Princeton researchers create a system to control the growth of microtubule branches, enabling precise chemical transport and potential applications in soft robotics, new medicines, and biomolecular transport. The technique harnesses cellular scaffolding to build novel materials and technologies.
A new model developed by MIT engineers predicts how certain shoe properties will affect a runner's performance, incorporating factors like stiffness and springiness. The model aims to help designers create high-performing shoes with novel properties.
Researchers at RIKEN successfully spin artificial spider silk that closely matches natural production, mimicking the complex molecular structure of silk. The eco-friendly innovation has potential benefits for environment and biomedical fields.
A team of researchers created a 3D bioprinted brain blood vessel model to investigate the impact of blood vessel curvature on metastatic cancer development. The model revealed that increased blood vessel curvature correlates with heightened cancer cell adherence and extravasation.
Researchers have enhanced microvascular sensitivity using ultrafast ultrasound, capturing the three-dimensional vascular network of renal arteries and veins without contrast agents. This technique reveals sharp decreases in renal blood flow during acute renal failure and chronic vascular degeneration in diabetic nephropathy.
A team of researchers has created artificial small-diameter vessels (SDVs) featuring pores that enable the formation of an endothelium without additional processing steps. The 3D-printed vessels were successfully infused with human cells, demonstrating spontaneous cellular assembly and paving the way for potential transplantation and f...
Aston University has established the Aston Institute for Membrane Excellence (AIME) with a £10m grant from Research England. The institute aims to develop novel biomimetic membranes through interdisciplinary collaboration between biology, physics, and chemistry.
Researchers at The University of Tokyo developed a bio-tagging method using dissolvable microneedle arrays for permanent animal identification. The approach, called 'MAPs,' uses customizable molds to tattoo unique identifiers into the skin, offering a safer and more humane alternative to traditional ear tags or RFID chips.
A soft, wearable robot was used to help a person living with Parkinson’s disease walk without freezing, eliminating the debilitating symptom and allowing them to regain their independence. The device provided instantaneous effects and consistently improved walking in a range of conditions.
A research team developed electrostatic materials capable of responding to weak ultrasound, generating static electricity for implantable neurological stimulators. The technology eliminates the need for batteries, reduces device size, and minimizes strain on the human body. Experimental validation confirms its effectiveness in animal m...
Researchers at UNIST developed a novel one-pot process for growing Bdellovibrio bacteriovorus, a predatory bacterium with potential as 'living antibiotics'. This approach eliminated the need for multiple vessels and reduced growth time by over 50%, enabling large-scale cultivation without compromising efficacy.
A team of researchers discovered a multiprotein complex involving NLRP3, AIM2, NLRC4, and Pyrin that drives PANoptosis, a type of programmed inflammatory cell death. The findings have implications for understanding inflammasome biology and identifying potential therapeutic targets.
Scientists use new photography technique to observe interaction between biological cell and shock wave, revealing high-speed phenomena. The technology has potential applications in science, medicine, and industry.
A world-first brain stimulation treatment is being developed to treat symptoms of Parkinson's disease and epilepsy using ultrasound technology. The endovascular focused ultrasound technique could significantly improve the quality of life for thousands of people living with neurological diseases.
Researchers have developed a mineral coating that maintains mRNA activity for up to six months at room temperature. This breakthrough enables the storage of mRNA therapeutics like COVID-19 vaccines on medical shelves, bridging the gap between rich and poor communities.
The National Science Foundation has awarded Lehigh University $6 million to develop a comprehensive, inclusive and accessible research translation ecosystem. The award supports the university's work in engineering, science, health, humanities, business, education and other areas to translate discoveries into practical solutions.
A team of researchers developed a theoretical framework that can reproduce and predict the patterns associated with gastrulation in a chicken embryo. Small changes in cell parameters and behavior can have a dramatic impact on the resulting gastrulation patterns, which are seen in other species such as frogs, fish, and chameleons.
Scientists have solved a decades-long puzzle and unveiled ultra-hard materials that rival diamond in toughness. The breakthrough could lead to multifunctional materials for industrial applications such as protective coatings and high-endurance cutting tools.
Researchers developed a method to measure microvascular changes in the skin using AI and optoacoustic imaging technology, enabling non-invasive assessment of diabetes severity. The study identified 32 significant changes in blood vessels, which can be used to monitor disease progression.
The new robotic replica, called RRV, can mimic healthy and diseased states, allowing scientists to test cardiac devices and therapies. The model can also be used to study the effects of mechanical ventilation on the right ventricle and develop strategies to prevent right heart failure.
A team of engineers has developed a novel printing method called deep-penetrating acoustic volumetric printing (DVAP) that uses soundwaves to solidify biologically compatible structures in deep tissues. The technique involves a specialized ink that reacts to ultrasound waves, enabling the creation of intricate structures for biomedical...
Researchers at University at Buffalo have discovered a way to create strong and effective fuel cell catalysts that approach the performance of platinum. By adding hydrogen to the fabricating process, they were able to balance durability and efficiency, potentially making fuel cells more affordable and polluting-free.
Researchers at McGill University discovered a strong, quick-release connection between living and non-living tissues in marine mussels. The biointerface is mediated by serotonergic cilia-based adhesion, which can be controlled by neurotransmitters serotonin and dopamine.
Researchers at MIT have developed an alternative method to study molecular signals in cells, allowing them to track up to seven different molecules simultaneously. The technique uses fluorescent proteins that flicker on and off at different rates, enabling the tracking of specific cellular functions over time.
Researchers at Wayne State University aim to extend the lifespan of infusion pumps and injection ports to minimize tissue damage and maintain site integrity. The project seeks to reduce inflammation and fibrosis caused by insulin phenolic preservatives, leading to improved diabetes management practices.
Researchers discover chemical injection strengthens sandy soil through increased cohesion and internal friction angle, with no long-term strength loss. The treatment also enhances water-sealing capacity, mitigating flood risks and improving infrastructure durability.
Researchers developed an integrated wearable sensor device using gold nanowires to measure multiple bio-signals simultaneously. The sensors demonstrated remarkable performance in detecting muscle tremors, heartbeat patterns, and body temperature changes.
Researchers have developed additively manufactured Ti-Ta-Cu alloys that exhibit improved biocompatibility and bacterial resistance, making them a promising alternative to traditional Ti6Al4V implants. The alloys were found to display remarkable synergistic effects in improving both in vivo biocompatibility and microbial resistance.
Researchers used machine learning to guide high-throughput experimental screening of small molecules, finding ones that improve vaccine response and reduce inflammation. The team discovered a molecule that outperforms the best immunomodulators on the market, with potential applications in cancer treatment.
Researchers are developing a bioengineered pancreas-like tissue using innovative biomaterials and engineered cells. The goal is to implant these cell-laden scaffolds into patients who need help managing their glucose levels.
Researchers at CSU and the University of St. Andrews created an effective antimicrobial material that slowly releases nitric oxide, killing bacteria and fungus over time.
A recent study by Harvard researchers provides an engineering approach to understanding the failure of macrophages in cancer therapies. The team found that different phenotypes exhibit different penetration into tumors, with M0 macrophages showing improved transport efficiency.
Researchers have developed a system that enables accurate force measurement in soft material-based actuators, allowing for arbitrarily long periods of constant force. The new material combinations reduce energy consumption by up to thousandfold, enabling the creation of low-cost and high-performance solutions for assistive devices and ...
A recent study published in Scientific Reports identified the risk of virus exposure during face-to-face encounters as peaking within 5 seconds. The researchers used a mobile full-scale mannequin and particle-tracking velocimetry system to visualize and measure aerosol particles derived from exhaled air.
Researchers from Austria and France join forces to unravel the secrets of gene regulation during mammalian development using stem cell-derived 3D culture models. The project aims to understand how key molecular events influence gene transcription and regulation over hours and days.
Scientists from Central South University develop a novel approach to address bacterial infection in bone transplantation by enriching H2O2 and amplifying the Fenton reaction. The technique enhances biocompatibility and safety, promising reduced transplant failures and post-operative complications.
Researchers created a hydrogel mat with magnetic microparticles that mimic the forces of exercise. The team found that regularly exercising muscle cells resulted in longer, aligned fibers, and improved contraction capabilities.
Researchers have developed soft implantable fibers that can deliver light to major nerves through the body, allowing for precise illumination of nerve pain. The fibers are flexible and stretch with the body, enabling scientists to study peripheral nerve disorders in animal models without constraining movement.
U of I researchers have developed organic nanozymes that mimic the properties of natural enzymes, exhibiting peroxidase-like activities and detecting glyphosate with adequate accuracy. The OC nanozyme is quicker to produce, cost-effective, non-toxic, and environmentally friendly.
Researchers propose a hybrid control strategy combining model-based optimization and in-cell feedback control to solve the process-model mismatch issue. This approach enhances the regulation of metabolic toggle switches, leading to increased isopropanol yields and robust microbial material production.
A study by researchers at the University of California - Riverside found that certain aspects of video game play can stimulate dopamine release and potentially aid in treating Parkinson's disease symptoms. The research suggests a promising new approach for managing the condition.
Researchers created a new CRISPR-based gene therapy tool using locally sourced, human-derived proteins that can activate silent or insufficiently expressed genes. The DREAM tool mimics the natural ability of human cells to turn on specific genes in response to mechanical cues.
Researchers have developed DeepMB, a neural network that reconstructs high-quality optoacoustic images about 1,000 times faster than state-of-the-art algorithms. This enables clinicians to access optimal MSOT image quality in real-time, positively impacting clinical studies and patient care.
A research team has discovered a novel approach to increase terpenoid production by fine-tuning isoprene pyrophosphate metabolism. The technique, which involves genetically encoded circuits, resulted in a remarkable increase in IPP synthesis and led to the production of high-value terpenoids.
Researchers at the University of California - San Diego developed screen-printed, flexible sensors that can record brain activity and lactate levels in earbuds. The sensors allow for long-term health monitoring and detection of neuro-degenerative conditions.
Five lung stem cell variants dominate CF lungs, causing inflammation, fibrosis, and mucin secretion. CFTR modulators fail to suppress these inflammatory variants, suggesting they as key targets for new drugs.
Jennifer Kane is studying how microbes interact with Miscanthus roots to boost productivity and sustainability. The research aims to understand what conditions enable the plant to prosper, with potential implications for bioenergy production on marginal lands.
Researchers developed an artificial, multisensory integrated neuron that combines visual and tactile input for improved navigation and decision-making. The system mimics the human brain's ability to integrate multiple senses, enhancing sensor technology's efficiency and paving the way for eco-friendly AI uses.
A digital twin of the bladder has been developed to simulate normal and bladder outlet obstruction (BOO)-affected function. The model will help researchers better understand the connection between changes in BOO bladder wall structure and functionality, enabling them to develop new treatments and predict treatment success rates.
Researchers at EPFL engineered E. coli bacteria to exhibit enhanced extracellular electron transfer, producing electricity while metabolizing organic substrates. The bioengineered E. coli surpassed previous approaches, generating three times more electrical current in various environments, including wastewater from a brewery.