Articles tagged with Bioengineering
Researchers developed a new AI-driven method to detect and predict defects in 3D printed metals, enabling rapid improvements in additive manufacturing. The method uses X-ray imaging and machine learning to identify pore generation in real-time with near-perfect accuracy.
A novel deep brain simulation approach has been developed to treat intractable epilepsy, with the potential to be a safer and more effective treatment than conventional methods. The sequential narrow-field stimulation method accurately detects seizure onset and alleviates symptoms while minimizing side effects.
The study found that the US uses mostly synthetic graphite, which is produced from fossil fuel industry by-products, while natural graphite is sourced from mines and imported. The researchers suggest increasing domestic production and recycling of graphite-containing products to reduce greenhouse gas emissions.
Scientists from SUTD design a novel thermal-based therapy nano-system that destroys over 20% of pancreatic cancer cells using microsecond electrical pulses, improving cancer cell targeting accuracy and bio-compatibility. The introduction of the M13 virus enhances electro-thermal therapy performance by assembling more on cancer cells.
Engineers at MIT and Caltech have developed an ingestible sensor that can track its location as it moves through the digestive tract, revealing where slowdowns in digestion may occur. The sensor uses a magnetic field produced by an electromagnetic coil outside the body to calculate its position.
Researchers have developed a new system to facilitate the diagnosis and treatment of gastrointestinal motility disorders. The ingestible 'smart pill' tracks movement through the GI tract using magnetic fields, allowing for more accurate and efficient diagnosis and targeted therapeutic interventions.
Researchers propose novel DNA-based conductive hydrogels with controlled elastic modulus and electrical properties matching those of nerve tissue. They plan to develop a strategy to control neurotrophic factors in the hydrogels to facilitate functional tissue regeneration.
Researchers at Rice University have developed a self-assembling peptide ink that enables the 3D printing of complex structures with cells, which can then be used to grow mature tissue in a petri dish. The ink allows for control over cell behavior using structural and chemical complexity.
Researchers have developed a gold nanoparticle probe to detect porcine epidemic diarrhoea virus (PEDV), a devastating disease causing severe diarrhoea and high death rates. The new tool promises fast, affordable diagnosis on-site, critical for preventing future outbreaks and protecting the industry from economic losses.
A new smart contact lens has been developed to diagnose and treat glaucoma by monitoring intraocular pressure in real-time and releasing the appropriate amount of medication. The lens, created by a POSTECH research team, uses a flexible drug delivery system and wireless power and communication system.
Researchers at Washington University in St. Louis have developed a non-invasive method called sonobiopsy that uses focused ultrasound to release neurodegenerative biomarkers into the blood, facilitating diagnosis of conditions like Alzheimer’s disease. The technique has shown promising results in releasing tau proteins and another biom...
Eleni Tomazou's project aims to create in vitro and in vivo models of pediatric sarcomas to accelerate drug discovery and precision medicine. Her work could lead to a significant impact on the treatment of these deadly cancers.
Researchers identified an alternative binding site on amyloid-beta aggregates using time-resolved spectroscopy and computational chemistry. This discovery could lead to the development of new therapies for Alzheimer's disease and other conditions associated with amyloid deposits.
Researchers at Aarhus University are developing a novel treatment for multiple sclerosis by spinning artificial nerve fibers using electro-spun fibres. The goal is to restore nerve impulses quickly, as the myelin sheath deteriorates with age.
Researchers at Beckman Institute for Advanced Science and Technology will use a unique combination of MRI and mass spectrometry imaging techniques to study Alzheimer's disease on an unprecedented scale. By capturing detailed chemical information, they aim to understand the molecular-level changes that occur in aging brains and develop ...
Researchers have designed a treatment that uses a modified bacterium to target and dissolve biofilms caused by Pseudomonas aeruginosa, a leading cause of hospital mortality. The treatment has shown significant efficacy in mice, reducing lung infections and doubling survival rates.
A new electromagnetic device has established a new standard of precision in mechanobiology research, enabling high-precision measurements of soft biological tissues. The device allows for the mechanical testing of human biopsy samples and has shown enhanced reliability with errors below 15%.
Scientists successfully used lab-produced tissue samples to remotely control muscle-driven miniature robots with this innovative technology. The device allows researchers a new level of interaction and exploration in the field of biological robots.
Researchers at Rice University have developed a new fluorescent dye that can cross the blood-brain barrier, allowing for noninvasive brain imaging and differentiation between healthy tissue and tumor cells. The dye's long-lasting fluorescence enables stable imaging over extended periods.
Researchers discovered that methanotroph Methylococcus capsulatus Bath can grow in the presence of small amounts of H2S using an enzyme switch. The study found that at 0.75% H2S concentration, bacteria switch from mxaF to xoxF, increasing methane consumption and mitigating greenhouse effects.
Researchers uncover ancient manufacturing strategy that incorporates self-healing functionalities into Roman concrete. Hot mixing process allows for faster construction and enhanced durability through spontaneous cracking and recrystallization.
The São Paulo School of Advanced Science on Stem Cell Biology will highlight the latest scientific advances in stem cell therapy and tissue bioengineering. Internationally renowned scientists will present state-of-the-art science and results of new research.
Researchers at Duke University discovered that glassfrogs store nearly 90% of their circulating red blood cells in their liver when they want to be transparent. This helps them blend in with their surroundings and avoid predation during the day.
The research team successfully transplanted a stem cell sheet onto the heart, promoting angiogenesis and improving cardiac function. The technique has improved integration and engraftment rates, addressing challenges in patch-based treatments for myocardial infarction.
Researchers have developed an edible plant-based ink derived from food waste to create cost-effective scaffolds for culturing meat. This innovation could significantly reduce the cost of large-scale cultured meat production, making it more affordable and environmentally friendly.
MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state. The protective molecules, known as glycans, prevent Vibrio cholerae from producing the toxin that usually leads to severe diarrhea.
Researchers discovered that eye movements can reveal valuable information about how humans make decisions. The study found that the speed and vigor of eye movements increased as participants considered their options before making a choice.
Researchers from Florida Atlantic University have developed a prototype of a novel wearable device that can continuously monitor physiological parameters associated with heart failure in real-time. The device uses sensors embedded in a lightweight belt to track thoracic impedance, electrocardiogram, heart rate, and motion activity, pro...
Researchers developed a new method to target diseased neurons using light, changing their long-term behavior. The approach uses light-sensitive enzymes to create insulating or conductive coatings on cell membranes, tuning excitability in neurons.
A new undergraduate research program at the University of Arizona aims to address local health issues in Arizona using a community-based approach. The PHIRE program recruits 60 students annually for training in health informatics and places them in research projects relevant to their communities.
Researchers developed a disposable, fast, and reliable biosensor system to detect putrescine in beef samples, improving food safety. The system uses cell-free protein synthesis and is designed to be consumer-friendly, empowering individuals to check the quality of their food.
A team of researchers from the University of Pennsylvania has developed a new algorithm, metadynamics, that can navigate high-dimensional energy landscapes to find low-energy configurations. This breakthrough has the potential to revolutionize fields such as protein folding and machine learning.
Researchers at the University of Missouri are developing a wearable heart monitor using a breathable material with antibacterial and antiviral properties. The device will track heart health via dual signals, providing continuous monitoring for early detection of heart disease.
Rice University researchers are developing implants that can produce and deliver monoclonal anti-HIV antibody therapeutics for at least a year. The project aims to reduce the cost and improve the logistics of HIV treatment, making it more accessible and beneficial for patients worldwide.
Researchers developed a biosensor using 'zero-dimensional' quantum dots and gold nanospheres to boost the accuracy of home-based continuous glucose monitoring. This enhances the sensitivity of electrochemical glucose sensors, making them suitable for everyday use.
A joint research team developed a new bioprocess by introducing a genetic circuit that induces cooperation among microorganisms, leading to improved productivity. The consortium, composed of Vibrio sp. dhg and E. coli strain, successfully acclimated to the genetic circuit, increasing 3-HP production 4.3-fold over simple co-culturing.
Kevin McHugh, a Rice bioengineer, has received the Distinguished Scientist Award from The Sontag Foundation for his work on gene editing to defeat glioblastoma multiforme. His approach involves delivering gene therapy agents directly to tumor cells, aiming to improve survival and reduce side effects.
A team of researchers from Korea investigated the dynamics of the p-Laplacian AC equation, finding that solutions maintain three criteria: phase separation, boundedness, and energy decay properties. They also identified an advantage of p-AC equation over classical Laplacian in adjusting interface sharpness.
Researchers are exploring how aging affects communication between bone and muscle, finding that imbalance can lead to muscle loss, falls, and bone fractures. They aim to develop novel interventions to restore this balance, potentially treating osteoporosis and sarcopenia.
Researchers developed a technique to 'see' fine structure and chemical composition of human cells with high resolution. The new method uses infrared light to reveal chemical signatures without fluorescent labeling.
A new microscopy system using optical tapered fibers has successfully acquired images of photoacoustic signals without contrast agents. The resolution is sufficient for cellular imaging, including red blood cells, with a resolution of 1.0 ± 0.3 micrometers.
A new reporter system called INSPECT allows for highly sensitive monitoring of both coding and non-coding RNA production, shedding light on cellular processes. This breakthrough tool modifies introns without altering completed RNA or proteins, offering a minimally invasive solution to study RNA regulation.
A handheld diagnostic lab developed by UCLA researchers can fully automate pooled testing and detect multiple diseases, reducing costs and usage of scarce supplies. The technology can be easily manufactured, deployed, and performed at a doctor's office or mass testing sites, helping authorities prepare for future pandemics.
MU researchers, including Jay J. Thelen and Dong Xu, are exploring genetic modification to increase seed oil production in camelina and pennycress for biofuel use in the aviation industry. The team aims to create a sustainable 'green energy' source as an alternative to petroleum-based fossil fuels.
Researchers at Binghamton University discover that sodium/proton exchanger 1 (NHE1) and SWELL1 proteins regulate cancer cell migration, offering insights into metastasis. The study's findings could have wide implications for slowing down or halting the deadly disease.
Researchers developed a single-cell Raman-based tool to efficiently mine live functional microbes from nature, eliminating the need for traditional culturing methods. This technique, called scRACS-Culture, allows for the direct screening and cultivation of cells with specific metabolic functions.
A new type of pacemaker that uses precise targeting capabilities to bypass pain receptors and reduce patient discomfort is being developed. The device, which uses light and optogenetics, could improve the quality of life for millions of people affected by atrial fibrillation.
Researchers at the University of New South Wales have developed optrodes that can measure neural activity using light, potentially revolutionizing medical technologies like nerve-operated prosthetics. The new approach addresses long-standing issues with impedance mismatch and crosstalk, paving the way for more complex neural networks.
Researchers at Brigham and Women's Hospital developed a novel bioink capable of constructing functional and mechanically strong blood vessels. The bioink enables bioprinting of conduits with key physiological characteristics similar to native vessels, potentially serving as vascular models for grafts in surgeries and disease studies.
The researchers developed a conformable multimodal sensor face mask (cMaSK) with 17 sensors around the edge of the mask that measure capacitance, temperature, humidity, air pressure, and other parameters. The study found that mask fit was significantly worse for women than men due to gender-related differences in face shape and size.
A research team at POSTECH developed a skin-attachable microphone sensor that clearly detects voices even in harsh noisy environments. This technology can be used for disaster-response communication between medical professionals wearing protective equipment and firefighters wearing gas masks.
Researchers at Pohang University of Science & Technology have developed technology to produce itaconic acid, a source material for bioplastic, using E. coli bacteria. This breakthrough enables mass production of bioplastic from steel mill gases, potentially transforming the plastics industry.
A Newcastle University study has developed a machine learning tool that can predict the performance properties of land plant Rubisco proteins with high accuracy. This prediction will enable researchers to identify and engineer 'supercharged' Rubisco proteins that can increase atmospheric CO2 uptake and store in crops such as wheat.
Researchers used small wheeled robots to study indirect mechanical interactions on deformable surfaces, finding that active matter can interact through non-contact forces. They created a model to control collective behavior by modifying robot design, mirroring celestial bodies' paths in Einstein's General Relativity.
A team of University of Missouri researchers is working to understand why solid-state lithium-ion batteries struggle with performance issues. They will use a specialized electron microscope and thin film polymer coatings to study the interface between the battery cathode and electrolyte, with the goal of developing an engineered interf...
Research found that STEM subjects have a social hierarchy based on stereotyped views of ideal students, which affects underrepresentation of women, people of color, and disabled students. Attitudes must shift to make STEM more inclusive and accessible.
The UK's Biotechnology and Biological Sciences Research Council has awarded £19 million to five world-class teams investigating bold ideas in bioscience. These projects will advance our understanding of fundamental rules of life, with potential implications for agriculture, health, biotechnology, and the green economy.
Researchers used the Advanced Photon Source to study asteroid fragments from Ryugu, finding they were made of water and carbon dioxide ice. The analysis suggests the asteroid formed over 4 billion years ago in the outer solar system, with a hydrated interior and dryer surface.
Researchers are developing wearable tonometric sensors that can collect blood pressure data without disrupting patients' sleep. The new cuffless monitoring system uses gecko-inspired adhesion technology to provide accurate readings.
Researchers at UVA will study organelles in cancer cells to identify new pathways for understanding and fighting cancer. By focusing on the interactions between genes, proteins, and organelles within cells, they hope to develop fresh clues about therapies.