Articles tagged with Bioengineering
Kevin McHugh, a Rice bioengineer, has received the Distinguished Scientist Award from The Sontag Foundation for his work on gene editing to defeat glioblastoma multiforme. His approach involves delivering gene therapy agents directly to tumor cells, aiming to improve survival and reduce side effects.
A team of researchers from Korea investigated the dynamics of the p-Laplacian AC equation, finding that solutions maintain three criteria: phase separation, boundedness, and energy decay properties. They also identified an advantage of p-AC equation over classical Laplacian in adjusting interface sharpness.
Researchers are exploring how aging affects communication between bone and muscle, finding that imbalance can lead to muscle loss, falls, and bone fractures. They aim to develop novel interventions to restore this balance, potentially treating osteoporosis and sarcopenia.
Researchers developed a technique to 'see' fine structure and chemical composition of human cells with high resolution. The new method uses infrared light to reveal chemical signatures without fluorescent labeling.
A new microscopy system using optical tapered fibers has successfully acquired images of photoacoustic signals without contrast agents. The resolution is sufficient for cellular imaging, including red blood cells, with a resolution of 1.0 ± 0.3 micrometers.
A new reporter system called INSPECT allows for highly sensitive monitoring of both coding and non-coding RNA production, shedding light on cellular processes. This breakthrough tool modifies introns without altering completed RNA or proteins, offering a minimally invasive solution to study RNA regulation.
A handheld diagnostic lab developed by UCLA researchers can fully automate pooled testing and detect multiple diseases, reducing costs and usage of scarce supplies. The technology can be easily manufactured, deployed, and performed at a doctor's office or mass testing sites, helping authorities prepare for future pandemics.
MU researchers, including Jay J. Thelen and Dong Xu, are exploring genetic modification to increase seed oil production in camelina and pennycress for biofuel use in the aviation industry. The team aims to create a sustainable 'green energy' source as an alternative to petroleum-based fossil fuels.
Researchers at Binghamton University discover that sodium/proton exchanger 1 (NHE1) and SWELL1 proteins regulate cancer cell migration, offering insights into metastasis. The study's findings could have wide implications for slowing down or halting the deadly disease.
Researchers developed a single-cell Raman-based tool to efficiently mine live functional microbes from nature, eliminating the need for traditional culturing methods. This technique, called scRACS-Culture, allows for the direct screening and cultivation of cells with specific metabolic functions.
A new type of pacemaker that uses precise targeting capabilities to bypass pain receptors and reduce patient discomfort is being developed. The device, which uses light and optogenetics, could improve the quality of life for millions of people affected by atrial fibrillation.
Researchers at Brigham and Women's Hospital developed a novel bioink capable of constructing functional and mechanically strong blood vessels. The bioink enables bioprinting of conduits with key physiological characteristics similar to native vessels, potentially serving as vascular models for grafts in surgeries and disease studies.
Researchers at the University of New South Wales have developed optrodes that can measure neural activity using light, potentially revolutionizing medical technologies like nerve-operated prosthetics. The new approach addresses long-standing issues with impedance mismatch and crosstalk, paving the way for more complex neural networks.
The researchers developed a conformable multimodal sensor face mask (cMaSK) with 17 sensors around the edge of the mask that measure capacitance, temperature, humidity, air pressure, and other parameters. The study found that mask fit was significantly worse for women than men due to gender-related differences in face shape and size.
A research team at POSTECH developed a skin-attachable microphone sensor that clearly detects voices even in harsh noisy environments. This technology can be used for disaster-response communication between medical professionals wearing protective equipment and firefighters wearing gas masks.
Researchers at Pohang University of Science & Technology have developed technology to produce itaconic acid, a source material for bioplastic, using E. coli bacteria. This breakthrough enables mass production of bioplastic from steel mill gases, potentially transforming the plastics industry.
A Newcastle University study has developed a machine learning tool that can predict the performance properties of land plant Rubisco proteins with high accuracy. This prediction will enable researchers to identify and engineer 'supercharged' Rubisco proteins that can increase atmospheric CO2 uptake and store in crops such as wheat.
Researchers used small wheeled robots to study indirect mechanical interactions on deformable surfaces, finding that active matter can interact through non-contact forces. They created a model to control collective behavior by modifying robot design, mirroring celestial bodies' paths in Einstein's General Relativity.
A team of University of Missouri researchers is working to understand why solid-state lithium-ion batteries struggle with performance issues. They will use a specialized electron microscope and thin film polymer coatings to study the interface between the battery cathode and electrolyte, with the goal of developing an engineered interf...
Research found that STEM subjects have a social hierarchy based on stereotyped views of ideal students, which affects underrepresentation of women, people of color, and disabled students. Attitudes must shift to make STEM more inclusive and accessible.
Researchers used the Advanced Photon Source to study asteroid fragments from Ryugu, finding they were made of water and carbon dioxide ice. The analysis suggests the asteroid formed over 4 billion years ago in the outer solar system, with a hydrated interior and dryer surface.
The UK's Biotechnology and Biological Sciences Research Council has awarded £19 million to five world-class teams investigating bold ideas in bioscience. These projects will advance our understanding of fundamental rules of life, with potential implications for agriculture, health, biotechnology, and the green economy.
Researchers are developing wearable tonometric sensors that can collect blood pressure data without disrupting patients' sleep. The new cuffless monitoring system uses gecko-inspired adhesion technology to provide accurate readings.
Researchers at UVA will study organelles in cancer cells to identify new pathways for understanding and fighting cancer. By focusing on the interactions between genes, proteins, and organelles within cells, they hope to develop fresh clues about therapies.
Researchers at UNSW Sydney have made significant discoveries about embryonic blood stem cell creation that could one day eliminate the need for blood stem cell donors. Two studies have emerged from UNSW researchers in this area that shine new light on how precursors to blood stem cells occur in animals and humans, and how they may be i...
Researchers have successfully inserted nanotubes into bacteria, allowing for the creation of
Researchers have genetically engineered yeast to produce vindoline and catharanthine, the precursors to vinblastine, a widely used anti-cancer drug. This breakthrough may lead to new sources of these compounds and reduce dependence on plant farming and logistics challenges.
Researchers developed a novel way to visualize densely packed molecules using expansion microscopy, allowing for the first time their imaging. The technique enables visualization of nanostructures found in neurons and Alzheimer's-linked amyloid beta plaques.
Researchers from UMass Amherst have created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue. This breakthrough device has the potential to lead-edge applications in cardiac-disease experiments and improve health monitoring for cardiac disease studies.
Research reveals that smaller artificial cells lead to greater separation of molecules, allowing for a new approach to manipulate material properties. This discovery has potential applications in pharmaceuticals and cosmetics industries.
SUTD researchers leverage nanosecond electroporation to deliver cancer-related molecules into living cells with excellent viability. The platform enables pores to remain open for up to 720 minutes, paving the way for efficient drug delivery and other applications.
MIT engineers create a flexible, semiconducting film that conforms to the skin like electronic Scotch tape, harnessing gallium nitride's piezoelectric properties for sensing and wireless communication. The device wirelessly transmits signals related to pulse, sweat, and UV exposure without chips or batteries.
Scientists have developed Live-seq, an innovative approach that keeps cells alive during RNA extraction for further study. This technique uses FluidFM to manipulate tiny volumes of fluids in a sample under the microscope, allowing for the insertion and extraction of mRNA from single cells without killing them.
A new device replicates short sections of human blood vessels allowing for variable flow conditions that mimic the body. Researchers can now watch what's happening inside treated grafts down to individual cells.
A new study uses high-resolution regional model experiments to explore how lake surface temperatures may affect the climate of the Great Lakes region. Small differences in lake surface temperatures can have a significant impact on summer climate and fuel extreme weather events.
Researchers at RCSI University have created a new lab-based model to test devices for heart failure with preserved ejection fraction. The model enables testing of the left atrium and ventricle, two independently controlled chambers that simulate blood flow during the resting phase.
Binghamton University researchers have developed a way to turn CDs into flexible biosensors that can monitor electrical activity in human hearts and muscles, as well as lactate, glucose, pH, and oxygen levels. The sensors are fabricated in 20-30 minutes without toxic chemicals or expensive equipment, costing around $1.50 per device.
A team of researchers at the University of Pittsburgh used computational modeling to investigate the immune response to avian flu. They found that the levels of interferon may be responsible for its more severe presentation and could hold the key to treating it.
Researchers have created a biodegradable seaweed-derived film that effectively absorbs sounds in the range of human voices, traffic, and music. The agar-based composite films outperform traditional acoustic foams in terms of sound-absorbing qualities.
Researchers have discovered a technique to remove phosphorus from wastewater at higher temperatures, using bacteria to store the chemical. The SCELSE-developed innovation extends the temperature range of enhanced biological phosphorus removal to 35 degrees Celsius.
Researchers at Tokyo University of Agriculture and Technology developed a new method to generate nano-sized plasma mist, which could be used in transdermal drug delivery systems. The method is safer than traditional electrostatic spray and has the potential to treat internal organs.
Researchers at Kobe University have successfully identified and disrupted genes in Pichia pastoris yeast to increase its secretory production of useful proteins. Through a series of processes, they developed new host strains that can produce high yields of proteins for industrial enzymes and biomedical antibodies.
A new strategy using nanoparticles restores damaged stem cells, enabling them to grow new tissues again. The approach, which uses specially formulated 'backpacks' to deliver medicine, shows promise for treating gestational diabetes and other pregnancy complications.
A team of researchers has successfully created complex artificial tissue models, including a full-scale human heart model, using focused rotary jet spinning. This method enables the creation of intricate details and spatially varying alignment, rivaling biological tissues in mechanical behavior.
Using nearly two decades of research and ultrabright X-ray beams, scientists have created a detailed structural map of the nuclear pore complex (NPC), a key regulator of cellular operations. The results provide significant implications for understanding disease mechanisms and developing new treatments.
Researchers at NIST found that gecko setae are coated in an ultra-thin layer of lipids, which repel water and help maintain grip on wet surfaces. This discovery could lead to the development of biomimetic products, such as gecko boots or gloves for improved traction.
Scientists have developed artificial photosynthesis to produce food in the dark, bypassing sunlight's need. This technology converts CO2, electricity, and water into acetate, a key component of vinegar, boosting food production's conversion efficiency up to 18 times.
Scientists have created a membrane made from a waste by-product of vegetable oil manufacturing that can filter out heavy metals from contaminated water. The membrane uses proteins derived from peanut or sunflower oil production to attract and trap heavy metal ions, purifying water to international drinking standards.
University of Missouri researchers develop wearable smart bioelectronic devices, including a 'smart' face mask that can monitor physiological status and detect respiratory problems. The masks also use laser-assisted fabrication to provide breathable soft electronics for better real-time health monitoring.
Researchers developed a scalable process for a biodegradable coating that protects against pathogenic and spoilage microorganisms, transportation damage, and reduces weight loss in avocados by 50%. The coating can be rinsed off with water and degrades in soil within three days.
Researchers discovered mistletoe viscin can be stretched into thin films or assembled into 3D structures, showing its potential as a wound sealant or skin covering. The material's reversible adhesive qualities make it highly versatile for diverse applications.
Researchers developed a novel nanobody-based detection method for recombinant human interferon α2b (rhIFNα2b), which has a lower detection limit than existing methods. The assay's operation time was shortened from two days to a few minutes, making it suitable for rapid market counterfeit detection and early diagnosis of hepatitis.
A team of researchers has found a way to block the replication of one strain of the influenza virus in human cells by inhibiting a specific protein modification process called SUMOylation. This breakthrough could lead to highly effective treatments for the flu and other respiratory viruses.
Researchers at University of Illinois at Urbana-Champaign have developed PlasmidMaker, an automated platform for designing and constructing plasmids. The platform uses Pyrococcus furiosus Argonaute-based artificial restriction enzymes to assemble DNA fragments with greater flexibility and precision.
Researchers developed PASTE, a method to analyze spatial transcriptomics data in three dimensions, enabling biologists to better understand cell environments and identify rare cell types. The technique can integrate information from multiple tissue slices, providing a more complete picture of gene expression within tissues.
A new nanosensor platform uses machine learning to analyze spectral signatures of carbon nanotubes for early detection of ovarian cancer. The approach detects biomarkers and recognizes the cancer itself, offering a promising alternative to traditional methods.
A novel network analysis technology can pinpoint seizure originating brain regions and predict a patient's seizure outcome before surgery, using only 10 minutes of resting state recordings.
Researchers found that maintaining hard water reduces zinc accumulation and oxidative stress in goldfish, mitigating toxic effects. This study provides an eco-friendly approach to address aquatic ecosystem pollution caused by heavy metal contamination.
Researchers from Harvard John A. Paulson School of Engineering and Applied Sciences have developed a single-material, single-stimuli microstructure that can outmaneuver even living cilia. These programmable structures could be used for soft robotics, biocompatible medical devices, and dynamic information encryption.
Researchers at Binghamton University have developed a system that kills SARS-CoV-2 viruses using UVC light, with optimal results achieved between 260-280 nanometers. The study's findings provide a scientific basis for standardizing and regulating claims from manufacturers of UV disinfectant devices.