Articles tagged with Bioengineering
Researchers will study temporomandibular joint function and disorders, aiming to understand the stresses on the joint before degeneration and develop new treatments. The project is a collaboration between Clemson University, Medical University of South Carolina, and National Institute of Dental and Craniofacial Research.
Researchers created implantable beads that produce high concentrations of interleukin-2, a natural compound activating white blood cells to fight cancer. The treatment eradicated ovarian and colorectal cancer in mice within six days, paving the way for human clinical trials later this year.
Researchers found that faster-moving ants in a raft lead to expansions and protrusions, potentially used for sensing environments. The team's findings can inform the development of intelligent swarm responses for robotics and next-generation materials.
A team of researchers has made a breakthrough in understanding how the brain processes visual information by studying populations of neurons across multiple brain areas. The study reveals that feedforward and feedback signaling involve different neural activity patterns, shedding new light on how the brain communicates with itself.
A new form of drug delivery microparticle mimics the properties of a red blood cell, enabling controlled release of drugs and targeting specific destinations. The goal is to bypass the body's filtration systems, allowing for improved efficacy and reduced negative side effects.
Northwestern University researchers used live imaging and computational tools to study the development of a fruit fly's compound eye. They found that cells move into position using mechanical forces, not just chemical signals. The discovery provides new insights into pattern formation in tissues.
Researchers created an artificial sensory receptor that generates spike signals on its own, enabling the e-skin to analyze spatial information and react to external stimuli in real-time. The e-skin's functionality overcomes limitations of conventional electronic skins, which can only process tactile information sequentially.
Researchers have made a significant breakthrough in predicting heart attacks and strokes by developing a non-invasive method using super-resolution ultrasound imaging. The technology aims to detect high-risk atherosclerotic plaques that are prone to rupture, allowing doctors to prescribe life-saving interventions.
Researchers develop a novel nanoplatform that can deliver drugs directly to T cells, which play a crucial role in immune reactions. The platform uses pH-sensitive dendrimers with phenylalanine and has shown promising results for cancer immunotherapy.
Researchers developed Inducible Directed Evolution (IDE), a new technique for controlling directed evolution in bacteria, allowing up to 30 gene modifications at a time. This approach enables finely tuned changes to bacteria, making it suitable for biopharmaceutical and chemical manufacturing industries.
A new method called DisCo enhances the efficiency of single-cell RNA sequencing by actively detecting and capturing cells using machine-vision. This approach allows for continuous operation and high capture efficiency, making it suitable for processing small cell samples such as tissues or patient biopsies.
Researcher Sepideh Razavi's work focuses on droplet wetting behavior, crucial for understanding disease transmission, industrial processes, and environmental sustainability. Her project aims to advance fundamental science for novel solutions in these fields.
Researchers developed a fully autonomous biohybrid fish from human stem-cell derived cardiac muscle cells that recreates the muscle contractions of a pumping heart. The device has two layers of muscle cells that work together to propel the fish for over 100 days.
Researchers at UC Davis Health have developed an engineered antibody, FuG1, that can interfere with the cell-to-cell transmission ability of SARS-CoV-2. The approach targets the furin enzyme, which is critical for viral transmissibility, and could be added to existing SARS-CoV-2 antibody cocktails.
Researchers create a sticky patch that can seal large tears and punctures in the colon, stomach, and intestines of animal models without causing inflammation or sticking to surrounding tissues. The patch is designed to be biocompatible, flexible, and holds for over a month.
Researchers at Northwestern University have developed a novel microfluidic device that can efficiently harvest and sort tumor-eating immune cells from tumors. This technology has shown dramatic results in shrinking tumors in mice compared to traditional methods.
Researchers at Rice University and Baylor College of Medicine have created an antibody with an engineered peptide that effectively targets and attacks bone tumors in breast cancer. The study shows the therapeutic efficacy is best when a moderate amount of the drug compound is delivered, offering new hope for treating bone metastases.
Researchers have created PicoShells, microscopic particles that can speed up the growth and analysis of microorganisms, including algae. This new tool enables faster identification of cell strains suitable for mass production, potentially shortening R&D timelines by months.
A study from Tohoku University reveals that ion size in electrolyte affects response time scale, enabling tuning for effective control. This discovery provides rational design guidelines for neuromorphic devices, paving the way for applications in artificial neural networks.
Regrowing healthy cartilage in damaged joints is a promising approach to treating arthritis. UConn bioengineers successfully regrowed cartilage in a rabbit's knee using piezoelectricity, a phenomenon that also exists in the human body.
A new study by Georgia Tech researchers has found a novel pathway for understanding why debilitating side effects occur with cancer treatment. The findings suggest that the central nervous system is vulnerable to cancer treatment's adverse effects, and correcting any one may not be enough to improve human function and quality of life.
Researchers have found that blocking mineralocorticoid receptors, a key factor in bone health, may help protect against bone loss and osteoporosis. This new target is thought to be more effective than previously believed logical targets, such as reducing glucocorticoid receptor activity.
Scientists created macroscopic living functional materials by adhering bacteria together, demonstrating improved mechanical properties and processability. The material can also self-heal within minutes and degrade organophosphate pesticides.
Scientists have grown rousette bat 'organoids' that reproduce intestines in vitro, providing a new model for studying virus-bat relationships. The organoids were found to be susceptible to certain viruses but not others, offering insights into why bats can host multiple pathogens without getting sick.
A team of researchers has identified a mechanical process by which sheets of cells morph into complex shapes, enabling organs to function. The process involves the production of hyaluronic acid, which swells with water and is constrained by thin connectors between cells.
A team of researchers from Chemnitz University of Technology, IFW Dresden, and Max Planck Institute CBG presents a new type of biomedical tool with a tiny biocompatible microelectronic micro-catheter. The catheter has sensor and actuator functions integrated into its wall, making it highly flexible and adaptable to the body.
Researchers have developed a method to store 3D-bioprinted tissues in a frozen state, allowing for long-term preservation and rapid thawing. The technique, known as cryobioprinting, has been shown to retain tissue functionality, enabling potential applications in drug testing and tissue replacement.
University of Minnesota researchers create a self-healing concrete alternative using bacteria-engineered silica, offering potential for biomedical applications. The study provides a framework for designing novel engineered living materials with improved strength and responsiveness.
Researchers discovered that mechanical forces guide cell development, influencing gene expression and potentially leading to pathologies like heart disease. The findings could inspire advances in engineering authentic artificial tissue for medical applications.
Scientists have developed a fusion protein that successfully blocks replication of SARS-CoV-2 and related viruses in cell culture tests. The protein combines ACE2 with human antibody fragments, providing reliable protection against future mutations.
A study published in Allergy reveals the importance of PU.1 transcription factor in regulating CCL17 gene expression, which contributes to allergic diseases. The research found that suppressing PU.1 can reduce inflammation in asthmatic mice, paving the way for novel treatments.
Researchers have expanded the number of naturally occurring CRISPR-Cas systems, giving a wealth of potential new tools for large-scale gene editing. The discovery could lead to treating complex diseases associated with multiple genes.
Researchers developed a new kind of organoid that grows both heart and gut cells together, mirroring their cooperation in embryonic development. This breakthrough could improve understanding of tissue communication and inform research into congenital disorders.
Researchers at the University of Pittsburgh aim to reduce workplace accidents by creating a predictive model of friction based on floor-surface topography. They will use advanced techniques such as scanning electron microscopy to measure small-scale features that affect shoe-floor friction.
Researchers discovered that humidity-driven movement in spore-bearing leaves is the key mechanism behind the unique timing of spore dispersal in the sensitive fern. The study found that dead fronds open when dry and close when wet due to differential cell expansion, a process also observed in pine cones.
Researchers developed an AI method to correct speed of sound aberrations in photoacoustic images, resulting in improved image quality and resolution. The technique reduced streak artifacts by up to 5% and increased signal-to-noise ratio by about 25 decibels.
A team of researchers from SUTD and A*STAR Bioinformatics Institute developed a combined electric current 2D material sensor to detect breast cancer cells. The ultra-sensitive sensor can identify electrical signals from a record low number of cancer cells, offering new possibilities in the field of biosensing.
Researchers at Harvard's Wyss Institute have developed a microfluidic Organ Chip device that accurately models cystic fibrosis lung airway pathology. The model replicates key pathological hallmarks, including mucus layer changes and inflammatory responses, providing a comprehensive preclinical human model for investigating new therapies.
A comprehensive assessment of polyurethane in the US reveals complexities that affect its recovery and recycling. The study highlights opportunities to enhance circularity and increase bio-based content of polyurethanes.
Researchers at the University at Buffalo have created model protein-RNA droplets with properties similar to those of viscoelastic Maxwell fluid and Silly Putty. These droplets exhibit dual behavior, acting like both elastic solids and viscous liquids, depending on the timescale.
A new liquid biopsy method developed by researchers at Pohang University of Science & Technology (POSTECH) demonstrates high sensitivity and specificity in detecting tumor DNA in the blood. The technique can detect even one to three specific tumor DNAs, offering a promising approach for early cancer diagnosis.
A new study from the University of Illinois explores the use of near-infrared spectroscopy to measure moisture content in real-time during the drying process of coated and uncoated apple chips. The technology offers several advantages, including speed, accuracy, and sustainability, over traditional methods.
A team of Lehigh University undergraduates has won the National Institutes of Health's Healthcare Technologies for Low-Resource Settings Prize for developing a diagnostic device to detect sickle cell disease in infants. The $15,000 prize will support further development and testing of the device, which could improve healthcare outcomes...
A team of researchers developed an innovative culture system that enables intestinal epithelial cells to form a three-dimensional villi microstructure. The BASIN system reproduces the structure and function of human intestinal epithelial cells simultaneously in multiple cell culture inserts.
A team of scientists successfully created a form of artificial vision for a blind woman using a prosthesis hardwired into her brain. The Moran|Cortivis Prosthesis enabled Gómez to identify lines, shapes, and simple letters evoked by different patterns of stimulation.
A new, bacteria-based system can detect cancer cells and release therapeutic drugs directly into them, leaving healthy cells intact. The technology has shown promising results in preclinical tests on mice, particularly for liver cancer.
Researchers at MIT have developed a new approach to treat cancer by combining chemotherapy, tumor injury, and immunotherapy. In mouse studies, the treatment eliminated tumors completely in nearly half of the mice and showed promise against various types of cancer.
Scientists develop a method to precisely control gas-liquid interfaces at the nanoscale, enabling precise enrichment of target molecules. The technology has potential applications in various fields, including chemical and biological processes.
Researchers from Michigan Technological University created a robot that uses Marangoni propulsion to move across liquid surfaces like insects. The robot's design is inspired by the ability of certain species to manipulate surface tension for speed and maneuverability.
Researchers at Beijing Institute of Technology created a robot that can track fast-moving rats for extended periods using real-time localization and movement analysis. The robotic rat's built-in stereo vision system enables it to characterize typical behaviors of actual rats, promoting autonomy and reproducibility in behavior research.
The study provides a unique genomic blueprint for understanding the complex mechanisms linking obesity with comorbidities like type 2 diabetes and cardiovascular diseases. The Ossabaw pig's genome is highly relevant to humans, making it an ideal model for studying human obesity.
Rice University's Neuroengineering Initiative is working on developing noninvasive systems to monitor and control the brain. Jerzy Szablowski aims to achieve single-cell precision in 15-20 years through innovative receptor development and gene therapy.
Researchers at Johns Hopkins University have developed a non-invasive optical probe to understand the complex changes in tumors after immunotherapy. Using Raman spectroscopy and machine learning, they identified key features that indicate how tumors respond to treatment, showing promising results for predicting patient response.
Researchers found that regular plants have distinct metabolic differences from CAM photosynthesis-adapted species, which could hinder efforts to bioengineer drought tolerance in crops. Understanding these differences is crucial for future research and potential crop improvement.
Researchers found that eating high-fibre whole grain rye products resulted in greater weight loss and body fat reduction compared to refined wheat alternatives. The study, involving 242 participants, suggests that rye's unique fibre content may contribute to its weight-loss benefits.
A team from The University of Tsukuba used microscopy techniques to analyze the microstructure of the ground beetle's wing casing, revealing a unique helical structure that creates optical effects. This finding has significant implications for the development of new biomimetic materials with enhanced performance.
Researchers at Rice University and the US Army are developing a portable skullcap that analyzes cerebrospinal fluid flow during sleep to clear metabolic waste. The goal is to noninvasively measure and modulate brain health in soldiers, potentially treating sleep disorders in real time.
Researchers developed a soft robotic steerable micro-catheter for precise brain surgery, enabling targeted treatment of cerebral disorders. The innovative catheter uses biomimicry to navigate and maneuver within the brain's complex anatomy.
Researchers adapted classical nucleation theory to understand protein assembly in cells, predicting precise locations and times for droplet formation. The approach offers a new understanding of cell biology and potential control over complex soft materials.
Researchers aim to replicate natural tendon development using embryonic chicken and mouse models, with a focus on mechanical stimulation and nanoparticle design.