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Just add sugar: Research shows common antioxidant can be more beneficial through glycosylation

Researchers have developed methods to produce polyphenolic compounds with improved solubility through microbial fermentation, enabling potential life-saving drugs. The process, called glycosylation, attaches sugar molecules to the compounds, making them more effective in preventing diseases such as cancer and heart disease.

SourceUtah State University·JournalBiotechnology Advances·TypeExperimental study·DateJun 14, 2023

Treadmill for microswimmers allows closer look at behavior

A team of researchers has created an acoustic microfluidic method to study swimming cells and microorganisms, including the single-cell alga Chlamydomonas reinhardtii. The device uses ultrasonic waves to trap cells in place without affecting their swimming behavior, enabling controlled experiments on cilia motion and cell motility.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJun 12, 2023

A lung injury therapy derived from adult skin cells

Researchers have developed a therapy using nanocarriers engineered from adult skin cells that curb inflammation and tissue injury in damaged mouse lungs. The treatment has shown promise for treating acute respiratory distress syndrome (ARDS), a condition that leads to respiratory failure and puts patients on ventilators.

SourceOhio State University·JournalAdvanced Materials·TypeExperimental study·DateJun 6, 2023

NIR spectroscopy provides easy, cost-effective method for food allergen testing

Researchers at the University of Illinois developed a new method using NIR spectroscopy to detect three types of allergens in quinoa flour. The method is non-destructive, non-invasive, and highly accurate, providing real-time results that can be performed with minimal training.

SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalJournal of Food Composition and Analysis·TypeExperimental study·DateMay 17, 2023

Insight into brain’s waste clearing system may shed light on brain diseases

Researchers at Washington University in St. Louis have found a way to enhance glymphatic transport using focused ultrasound with microbubbles, opening new opportunities for studying brain diseases and function. The non-invasive method shows promise for potentially mitigating neurodegenerative diseases like Alzheimer's and Parkinson's.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 16, 2023

Tiny microbes could brew big benefits for green biomanufacturing

Researchers have engineered bacteria to combine natural enzymatic reactions with the carbene transfer reaction, producing new-to-nature carbon products that can be used in biochemicals and advanced biofuels. This breakthrough could reduce industrial emissions by providing sustainable alternatives to chemical manufacturing processes.

SourceDOE/Lawrence Berkeley National Laboratory·JournalNature·TypeExperimental study·DateMay 8, 2023

Development of an artificial kidney for early detection of drug toxicity

A research team from Pohang University of Science & Technology has engineered an artificial kidney to detect adverse drug reactions and provide personalized treatment. The team successfully fabricated a glomerular microvessel-on-a-chip that recapitulates the kidney's filtering function and evaluates its response to various toxins.

James Chappell wins NSF CAREER Award

James Chappell, a Rice University bioscientist, has won a National Science Foundation CAREER Award to create RNA programming methods for microbial communities in natural habitats. His research aims to improve human health and the environment by genetically manipulating microbial communities.

Hitchhiker plants inspire improved techniques for reattaching tendon to bone

Researchers developed a new approach to suturing based on the mechanics and spacing of a hitchhiker plant's attachment system, promising to balance forces across sutures and reduce failure rates in surgical procedures. The findings were published in Proceedings of the Royal Society A.

SourceWashington University in St. Louis·JournalProceedings of the Royal Society A Mathematical Physical and Engineering Sciences·DateMar 14, 2023

Attracting stem cells and facilitating bone regeneration by adhesive protein

A new coating material developed by Korean researchers facilitates bone regeneration and attracts osteo-progenitor cells, significantly improving the success rate of dental implants. The coating, loaded with BMP-2, prevents non-osteogenic cell invasion and induces high bone differentiation in a short period.

SourcePohang University of Science & Technology (POSTECH)·JournalBioengineering & Translational Medicine·DateMar 13, 2023

SUTD researchers developed novel 2D material with virus to kill cancer cells

Scientists from SUTD design a novel thermal-based therapy nano-system that destroys over 20% of pancreatic cancer cells using microsecond electrical pulses, improving cancer cell targeting accuracy and bio-compatibility. The introduction of the M13 virus enhances electro-thermal therapy performance by assembling more on cancer cells.

NYUAD researcher and colleagues develop novel “smart pills” that improve the diagnosis and treatment of gastrointestinal disorders

Researchers have developed a new system to facilitate the diagnosis and treatment of gastrointestinal motility disorders. The ingestible 'smart pill' tracks movement through the GI tract using magnetic fields, allowing for more accurate and efficient diagnosis and targeted therapeutic interventions.

SourceNew York University·JournalNature Electronics·DateFeb 13, 2023

Peptide 3D-printing inks could advance regenerative medicine

Researchers at Rice University have developed a self-assembling peptide ink that enables the 3D printing of complex structures with cells, which can then be used to grow mature tissue in a petri dish. The ink allows for control over cell behavior using structural and chemical complexity.

SourceRice University·JournalAdvanced Materials·TypeExperimental study·DateFeb 7, 2023

Focused ultrasound technique leads to release of neurodegenerative disorders biomarkers

Researchers at Washington University in St. Louis have developed a non-invasive method called sonobiopsy that uses focused ultrasound to release neurodegenerative biomarkers into the blood, facilitating diagnosis of conditions like Alzheimer’s disease. The technique has shown promising results in releasing tau proteins and another biom...

SourceWashington University in St. Louis·JournalRadiology·TypeExperimental study·DateJan 31, 2023

New fluorescent dye can light up the brain

Researchers at Rice University have developed a new fluorescent dye that can cross the blood-brain barrier, allowing for noninvasive brain imaging and differentiation between healthy tissue and tumor cells. The dye's long-lasting fluorescence enables stable imaging over extended periods.

SourceRice University·JournalJournal of the American Chemical Society·TypeExperimental study·DateJan 17, 2023

Novel wearable belt with sensors accurately monitors heart failure 24/7

Researchers from Florida Atlantic University have developed a prototype of a novel wearable device that can continuously monitor physiological parameters associated with heart failure in real-time. The device uses sensors embedded in a lightweight belt to track thoracic impedance, electrocardiogram, heart rate, and motion activity, pro...

SourceFlorida Atlantic University·JournalScientific Reports·TypeExperimental study·DateDec 12, 2022

Glassy discovery offers computational windfall to researchers across disciplines

A team of researchers from the University of Pennsylvania has developed a new algorithm, metadynamics, that can navigate high-dimensional energy landscapes to find low-energy configurations. This breakthrough has the potential to revolutionize fields such as protein folding and machine learning.

SourceUniversity of Pennsylvania School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateDec 5, 2022

A genetic circuit guides microorganisms to stop fighting and work together in a cell factory

A joint research team developed a new bioprocess by introducing a genetic circuit that induces cooperation among microorganisms, leading to improved productivity. The consortium, composed of Vibrio sp. dhg and E. coli strain, successfully acclimated to the genetic circuit, increasing 3-HP production 4.3-fold over simple co-culturing.

SourcePohang University of Science & Technology (POSTECH)·JournalNature Communications·DateNov 28, 2022