Articles tagged with Bioengineering
Researchers at UNSW Sydney have made significant discoveries about embryonic blood stem cell creation that could one day eliminate the need for blood stem cell donors. Two studies have emerged from UNSW researchers in this area that shine new light on how precursors to blood stem cells occur in animals and humans, and how they may be i...
Researchers have successfully inserted nanotubes into bacteria, allowing for the creation of
Researchers have genetically engineered yeast to produce vindoline and catharanthine, the precursors to vinblastine, a widely used anti-cancer drug. This breakthrough may lead to new sources of these compounds and reduce dependence on plant farming and logistics challenges.
Researchers developed a novel way to visualize densely packed molecules using expansion microscopy, allowing for the first time their imaging. The technique enables visualization of nanostructures found in neurons and Alzheimer's-linked amyloid beta plaques.
Researchers from UMass Amherst have created a tiny sensor that can simultaneously measure electrical and mechanical cellular responses in cardiac tissue. This breakthrough device has the potential to lead-edge applications in cardiac-disease experiments and improve health monitoring for cardiac disease studies.
Research reveals that smaller artificial cells lead to greater separation of molecules, allowing for a new approach to manipulate material properties. This discovery has potential applications in pharmaceuticals and cosmetics industries.
SUTD researchers leverage nanosecond electroporation to deliver cancer-related molecules into living cells with excellent viability. The platform enables pores to remain open for up to 720 minutes, paving the way for efficient drug delivery and other applications.
MIT engineers create a flexible, semiconducting film that conforms to the skin like electronic Scotch tape, harnessing gallium nitride's piezoelectric properties for sensing and wireless communication. The device wirelessly transmits signals related to pulse, sweat, and UV exposure without chips or batteries.
Scientists have developed Live-seq, an innovative approach that keeps cells alive during RNA extraction for further study. This technique uses FluidFM to manipulate tiny volumes of fluids in a sample under the microscope, allowing for the insertion and extraction of mRNA from single cells without killing them.
A new device replicates short sections of human blood vessels allowing for variable flow conditions that mimic the body. Researchers can now watch what's happening inside treated grafts down to individual cells.
A new study uses high-resolution regional model experiments to explore how lake surface temperatures may affect the climate of the Great Lakes region. Small differences in lake surface temperatures can have a significant impact on summer climate and fuel extreme weather events.
Researchers at RCSI University have created a new lab-based model to test devices for heart failure with preserved ejection fraction. The model enables testing of the left atrium and ventricle, two independently controlled chambers that simulate blood flow during the resting phase.
Binghamton University researchers have developed a way to turn CDs into flexible biosensors that can monitor electrical activity in human hearts and muscles, as well as lactate, glucose, pH, and oxygen levels. The sensors are fabricated in 20-30 minutes without toxic chemicals or expensive equipment, costing around $1.50 per device.
A team of researchers at the University of Pittsburgh used computational modeling to investigate the immune response to avian flu. They found that the levels of interferon may be responsible for its more severe presentation and could hold the key to treating it.
Researchers have created a biodegradable seaweed-derived film that effectively absorbs sounds in the range of human voices, traffic, and music. The agar-based composite films outperform traditional acoustic foams in terms of sound-absorbing qualities.
Researchers have discovered a technique to remove phosphorus from wastewater at higher temperatures, using bacteria to store the chemical. The SCELSE-developed innovation extends the temperature range of enhanced biological phosphorus removal to 35 degrees Celsius.
Researchers at Tokyo University of Agriculture and Technology developed a new method to generate nano-sized plasma mist, which could be used in transdermal drug delivery systems. The method is safer than traditional electrostatic spray and has the potential to treat internal organs.
A new strategy using nanoparticles restores damaged stem cells, enabling them to grow new tissues again. The approach, which uses specially formulated 'backpacks' to deliver medicine, shows promise for treating gestational diabetes and other pregnancy complications.
A team of researchers has successfully created complex artificial tissue models, including a full-scale human heart model, using focused rotary jet spinning. This method enables the creation of intricate details and spatially varying alignment, rivaling biological tissues in mechanical behavior.
Researchers at Kobe University have successfully identified and disrupted genes in Pichia pastoris yeast to increase its secretory production of useful proteins. Through a series of processes, they developed new host strains that can produce high yields of proteins for industrial enzymes and biomedical antibodies.
Using nearly two decades of research and ultrabright X-ray beams, scientists have created a detailed structural map of the nuclear pore complex (NPC), a key regulator of cellular operations. The results provide significant implications for understanding disease mechanisms and developing new treatments.
Researchers at NIST found that gecko setae are coated in an ultra-thin layer of lipids, which repel water and help maintain grip on wet surfaces. This discovery could lead to the development of biomimetic products, such as gecko boots or gloves for improved traction.
Scientists have created a membrane made from a waste by-product of vegetable oil manufacturing that can filter out heavy metals from contaminated water. The membrane uses proteins derived from peanut or sunflower oil production to attract and trap heavy metal ions, purifying water to international drinking standards.
University of Missouri researchers develop wearable smart bioelectronic devices, including a 'smart' face mask that can monitor physiological status and detect respiratory problems. The masks also use laser-assisted fabrication to provide breathable soft electronics for better real-time health monitoring.
Scientists have developed artificial photosynthesis to produce food in the dark, bypassing sunlight's need. This technology converts CO2, electricity, and water into acetate, a key component of vinegar, boosting food production's conversion efficiency up to 18 times.
Researchers developed a scalable process for a biodegradable coating that protects against pathogenic and spoilage microorganisms, transportation damage, and reduces weight loss in avocados by 50%. The coating can be rinsed off with water and degrades in soil within three days.
Researchers discovered mistletoe viscin can be stretched into thin films or assembled into 3D structures, showing its potential as a wound sealant or skin covering. The material's reversible adhesive qualities make it highly versatile for diverse applications.
Researchers developed a novel nanobody-based detection method for recombinant human interferon α2b (rhIFNα2b), which has a lower detection limit than existing methods. The assay's operation time was shortened from two days to a few minutes, making it suitable for rapid market counterfeit detection and early diagnosis of hepatitis.
A team of researchers has found a way to block the replication of one strain of the influenza virus in human cells by inhibiting a specific protein modification process called SUMOylation. This breakthrough could lead to highly effective treatments for the flu and other respiratory viruses.
Researchers at University of Illinois at Urbana-Champaign have developed PlasmidMaker, an automated platform for designing and constructing plasmids. The platform uses Pyrococcus furiosus Argonaute-based artificial restriction enzymes to assemble DNA fragments with greater flexibility and precision.
A new nanosensor platform uses machine learning to analyze spectral signatures of carbon nanotubes for early detection of ovarian cancer. The approach detects biomarkers and recognizes the cancer itself, offering a promising alternative to traditional methods.
Researchers developed PASTE, a method to analyze spatial transcriptomics data in three dimensions, enabling biologists to better understand cell environments and identify rare cell types. The technique can integrate information from multiple tissue slices, providing a more complete picture of gene expression within tissues.
A novel network analysis technology can pinpoint seizure originating brain regions and predict a patient's seizure outcome before surgery, using only 10 minutes of resting state recordings.
Researchers found that maintaining hard water reduces zinc accumulation and oxidative stress in goldfish, mitigating toxic effects. This study provides an eco-friendly approach to address aquatic ecosystem pollution caused by heavy metal contamination.
Researchers from Harvard John A. Paulson School of Engineering and Applied Sciences have developed a single-material, single-stimuli microstructure that can outmaneuver even living cilia. These programmable structures could be used for soft robotics, biocompatible medical devices, and dynamic information encryption.
Researchers at Binghamton University have developed a system that kills SARS-CoV-2 viruses using UVC light, with optimal results achieved between 260-280 nanometers. The study's findings provide a scientific basis for standardizing and regulating claims from manufacturers of UV disinfectant devices.
A new nanofiber-based biodegradable millirobot called Fibot can move in the intestines and release different drugs at anchored positions. Fibot's degradation capability is pH-responsive, allowing for controlled drug release.
A new study by University of California, Riverside researchers has found that coral-algal symbiosis can initiate without photosynthesis. This breakthrough could help corals survive climate change and ultimately save coral reefs.
Researchers at Binghamton University have discovered that human skin's unique structure allows it to maximize both durability and flexibility. The team created artificial skin membranes that mimicked the structure of mammalian skin, testing their puncture toughness and deformability.
Researchers developed a high-performance microscopy system for non-invasive examination of conjunctival goblet cells, allowing for real-time imaging in live animal models and human patients. The system enables high-resolution images of CGCs without causing harm to the subject.
Rice University and MD Anderson Cancer Center will train future medical professionals to translate nanotechnology advances to the clinic, focusing on cancer diagnosis and treatment. The five-year program aims to recruit 16 fellows from underrepresented groups.
Researchers have engineered a tiny living heart chamber replica to study disease progression and test new treatments. The miniPUMP device mimics the real organ's mechanics, allowing for accurate tracking of how the heart grows in embryos and studying the impact of disease.
Researchers at Gwangju Institute of Science and Technology (GIST) have developed a new technique to easily visualize viruses using an optical microscope, called the Gires-Tournois immunoassay platform. The platform uses 'slow light' technology to detect coronavirus particles by slowing down light that gets reflected around them.
A new portable COVID-19 test can detect and differentiate the alpha variant of the SARS-CoV-2 virus from earlier strains in saliva samples. The test uses a genetic phenomenon called S-gene target failure to identify the alpha variant, and can be used at home or other settings.
Researchers at Kobe University have discovered a new mechanism by which E. coli captures glucose and secretes it as glucose-6-phosphate (G6P), leading to increased production of target compounds. By trapping the secreted G6P on the surface of the bacteria, they developed a novel technique to improve bioproduction efficiency.
Researchers from Osaka University engineered microorganisms to use light as an external energy source, accelerating biomanufacturing of target compounds without disrupting the host microorganism's natural metabolism. This approach has the potential to increase efficiency and reduce carbon emissions in bioprocesses.
Researchers aim to replicate buzz pollination using microrobots to understand its importance in agriculture and conservation. The project could lead to stronger motivation for conserving diverse bee species and optimizing fruit and vegetable yields.
Recent studies published in the Journal of Pharmaceutical Analysis have found applications of nanotechnology in medicine, drug research, and environmental protection. Researchers developed nanodots made of carbon using natural polysaccharides from mushrooms to detect chromium, and created nanozymes that could be used to detect drug con...
Researchers at UC Riverside have discovered that curcumin promotes vascular endothelial growth factor (VEGF) secretion, helping to grow engineered blood vessels and tissues. The study uses magnetic hydrogels coated with curcumin-coated nanoparticles, which gradually release the compound without injuring cells.
Researchers use DNA to program metal nanoparticles to assemble into new configurations, resulting in the discovery of three new crystalline phases. The approach enables symmetry breaking and creation of complex colloidal crystal structures with unique optical and catalytic properties.
Researchers at the University of Illinois Chicago have developed a new cell-laden bioink that enables the production of complex, shape-changing bioconstructs. These 4D constructs have the potential to mimic the body's natural developmental processes and could lead to advances in tissue engineering.
Orb-weaver spiders have been found to use their massive webs as auditory arrays, capturing sounds and giving them advanced warning of prey or predators. The researchers used a special quiet room and placed a mini-speaker near the web, causing the spider to detect and respond.
Researchers at Argonne National Laboratory have discovered a key reason for the performance decline of sodium-ion batteries, which are promising candidates for replacing lithium-ion materials. By adjusting synthesis conditions, they can fabricate far superior cathodes that will maintain performance with long-term cycling.
In an animal study, researchers created an implantable biotechnology called MASTER that produces and releases CAR-T cells for attacking cancerous tumors. This technology reduces the manufacturing time from weeks to hours, increasing efficiency and effectiveness.
Researchers developed long-lived biological computers using RNA, which can persist inside cells. Unlike DNA-based devices, these RNA circuits are dependable and versatile, enabling continuous production in living cells.
Researchers at Northwestern University developed an AI-assisted Nanofountain Probe Electroporation system to engineer stem cells. The new method reduces cell loss and increases throughput, enabling selective manipulation of individual cells in micro-arrays.
Researchers at the University of Birmingham identified a new gene, Highlander, that regulates self-incompatibility in plants. The discovery opens up new avenues for improving crop yields and resistance to disease.
Scientists at Stanford University have developed a new method for controlling specific brain cells and circuits using infrared light. Researchers successfully stimulated neurons in mice by shining infrared light through the skull, demonstrating the potential for flexible testing of brain functions during normal behavior.
Researchers at Karolinska Institutet have found a way to stabilize the cancer-suppressing protein p53 by adding a spider silk protein, creating a more potent variant. This discovery has potential as an approach for cancer therapy.
Researchers will study temporomandibular joint function and disorders, aiming to understand the stresses on the joint before degeneration and develop new treatments. The project is a collaboration between Clemson University, Medical University of South Carolina, and National Institute of Dental and Craniofacial Research.