Articles tagged with Bioengineering
Researchers have developed a method to store 3D-bioprinted tissues in a frozen state, allowing for long-term preservation and rapid thawing. The technique, known as cryobioprinting, has been shown to retain tissue functionality, enabling potential applications in drug testing and tissue replacement.
University of Minnesota researchers create a self-healing concrete alternative using bacteria-engineered silica, offering potential for biomedical applications. The study provides a framework for designing novel engineered living materials with improved strength and responsiveness.
Researchers discovered that mechanical forces guide cell development, influencing gene expression and potentially leading to pathologies like heart disease. The findings could inspire advances in engineering authentic artificial tissue for medical applications.
Scientists have developed a fusion protein that successfully blocks replication of SARS-CoV-2 and related viruses in cell culture tests. The protein combines ACE2 with human antibody fragments, providing reliable protection against future mutations.
A study published in Allergy reveals the importance of PU.1 transcription factor in regulating CCL17 gene expression, which contributes to allergic diseases. The research found that suppressing PU.1 can reduce inflammation in asthmatic mice, paving the way for novel treatments.
Researchers have expanded the number of naturally occurring CRISPR-Cas systems, giving a wealth of potential new tools for large-scale gene editing. The discovery could lead to treating complex diseases associated with multiple genes.
Researchers developed a new kind of organoid that grows both heart and gut cells together, mirroring their cooperation in embryonic development. This breakthrough could improve understanding of tissue communication and inform research into congenital disorders.
Researchers discovered that humidity-driven movement in spore-bearing leaves is the key mechanism behind the unique timing of spore dispersal in the sensitive fern. The study found that dead fronds open when dry and close when wet due to differential cell expansion, a process also observed in pine cones.
Researchers at the University of Pittsburgh aim to reduce workplace accidents by creating a predictive model of friction based on floor-surface topography. They will use advanced techniques such as scanning electron microscopy to measure small-scale features that affect shoe-floor friction.
A team of researchers from SUTD and A*STAR Bioinformatics Institute developed a combined electric current 2D material sensor to detect breast cancer cells. The ultra-sensitive sensor can identify electrical signals from a record low number of cancer cells, offering new possibilities in the field of biosensing.
Researchers developed an AI method to correct speed of sound aberrations in photoacoustic images, resulting in improved image quality and resolution. The technique reduced streak artifacts by up to 5% and increased signal-to-noise ratio by about 25 decibels.
Researchers at Harvard's Wyss Institute have developed a microfluidic Organ Chip device that accurately models cystic fibrosis lung airway pathology. The model replicates key pathological hallmarks, including mucus layer changes and inflammatory responses, providing a comprehensive preclinical human model for investigating new therapies.
A comprehensive assessment of polyurethane in the US reveals complexities that affect its recovery and recycling. The study highlights opportunities to enhance circularity and increase bio-based content of polyurethanes.
Researchers at the University at Buffalo have created model protein-RNA droplets with properties similar to those of viscoelastic Maxwell fluid and Silly Putty. These droplets exhibit dual behavior, acting like both elastic solids and viscous liquids, depending on the timescale.
A new liquid biopsy method developed by researchers at Pohang University of Science & Technology (POSTECH) demonstrates high sensitivity and specificity in detecting tumor DNA in the blood. The technique can detect even one to three specific tumor DNAs, offering a promising approach for early cancer diagnosis.
A new study from the University of Illinois explores the use of near-infrared spectroscopy to measure moisture content in real-time during the drying process of coated and uncoated apple chips. The technology offers several advantages, including speed, accuracy, and sustainability, over traditional methods.
A team of researchers developed an innovative culture system that enables intestinal epithelial cells to form a three-dimensional villi microstructure. The BASIN system reproduces the structure and function of human intestinal epithelial cells simultaneously in multiple cell culture inserts.
A team of Lehigh University undergraduates has won the National Institutes of Health's Healthcare Technologies for Low-Resource Settings Prize for developing a diagnostic device to detect sickle cell disease in infants. The $15,000 prize will support further development and testing of the device, which could improve healthcare outcomes...
A team of scientists successfully created a form of artificial vision for a blind woman using a prosthesis hardwired into her brain. The Moran|Cortivis Prosthesis enabled Gómez to identify lines, shapes, and simple letters evoked by different patterns of stimulation.
A new, bacteria-based system can detect cancer cells and release therapeutic drugs directly into them, leaving healthy cells intact. The technology has shown promising results in preclinical tests on mice, particularly for liver cancer.
Scientists develop a method to precisely control gas-liquid interfaces at the nanoscale, enabling precise enrichment of target molecules. The technology has potential applications in various fields, including chemical and biological processes.
Researchers from Michigan Technological University created a robot that uses Marangoni propulsion to move across liquid surfaces like insects. The robot's design is inspired by the ability of certain species to manipulate surface tension for speed and maneuverability.
Researchers at MIT have developed a new approach to treat cancer by combining chemotherapy, tumor injury, and immunotherapy. In mouse studies, the treatment eliminated tumors completely in nearly half of the mice and showed promise against various types of cancer.
Researchers at Beijing Institute of Technology created a robot that can track fast-moving rats for extended periods using real-time localization and movement analysis. The robotic rat's built-in stereo vision system enables it to characterize typical behaviors of actual rats, promoting autonomy and reproducibility in behavior research.
The study provides a unique genomic blueprint for understanding the complex mechanisms linking obesity with comorbidities like type 2 diabetes and cardiovascular diseases. The Ossabaw pig's genome is highly relevant to humans, making it an ideal model for studying human obesity.
Rice University's Neuroengineering Initiative is working on developing noninvasive systems to monitor and control the brain. Jerzy Szablowski aims to achieve single-cell precision in 15-20 years through innovative receptor development and gene therapy.
Researchers at Johns Hopkins University have developed a non-invasive optical probe to understand the complex changes in tumors after immunotherapy. Using Raman spectroscopy and machine learning, they identified key features that indicate how tumors respond to treatment, showing promising results for predicting patient response.
Researchers found that eating high-fibre whole grain rye products resulted in greater weight loss and body fat reduction compared to refined wheat alternatives. The study, involving 242 participants, suggests that rye's unique fibre content may contribute to its weight-loss benefits.
Researchers found that regular plants have distinct metabolic differences from CAM photosynthesis-adapted species, which could hinder efforts to bioengineer drought tolerance in crops. Understanding these differences is crucial for future research and potential crop improvement.
A team from The University of Tsukuba used microscopy techniques to analyze the microstructure of the ground beetle's wing casing, revealing a unique helical structure that creates optical effects. This finding has significant implications for the development of new biomimetic materials with enhanced performance.
Researchers at Rice University and the US Army are developing a portable skullcap that analyzes cerebrospinal fluid flow during sleep to clear metabolic waste. The goal is to noninvasively measure and modulate brain health in soldiers, potentially treating sleep disorders in real time.
Researchers developed a soft robotic steerable micro-catheter for precise brain surgery, enabling targeted treatment of cerebral disorders. The innovative catheter uses biomimicry to navigate and maneuver within the brain's complex anatomy.
A chemical engineer is developing a novel biomaterial that can mimic the response of pediatric brain cancers to different approaches, allowing for customized treatment plans. The material will be designed to simulate the growth environment of cancer cells inside a tumor and can be used with patient-derived cells.
Researchers adapted classical nucleation theory to understand protein assembly in cells, predicting precise locations and times for droplet formation. The approach offers a new understanding of cell biology and potential control over complex soft materials.
Researchers aim to replicate natural tendon development using embryonic chicken and mouse models, with a focus on mechanical stimulation and nanoparticle design.
Researchers from FAU and MIT develop a microfluidic assay to study the mechanical performance of red blood cells under hypoxic conditions. The study reveals that cyclic hypoxia can lead to mechanical degradation of the red blood cell membrane, contributing to aging.
A Rice University professor has received a $2.4 million grant from the NIH to develop open-source software for designing personalized treatments for movement impairments using computational modeling and simulation. The software will create customized computer models of individual patients, optimizing treatment solutions.
A recent study employs machine learning to guide the design of novel materials for CO2 capture, identifying elemental composition and textural properties as key factors. The research team's findings suggest prioritizing adsorption parameters and surface area optimization for high CO2 adsorption efficiency.
Scientists from Trinity College Dublin have developed tiny, color-changing gas sensors using new materials and 3D printing techniques. These sensors can detect solvent vapors in air and have potential applications in wearable devices for health monitoring and low-cost environmental monitoring systems.
Researchers discover brain forms a single motor plan to optimize task performance despite uncertainty, upending decades-old theory of motor averaging. The study used experiments and computational modeling to demonstrate the brain's ability to generate an optimal action choice under uncertain conditions.
Researchers at Tel Aviv University have created a system that enables the production of 'good' bacteria capable of eliminating 'bad' bacteria. This breakthrough technology uses a toxin injection system to target specific types and amounts of toxins, offering an alternative to antibiotics.
A team of researchers from the Beckman Institute for Advanced Science and Technology has developed a fast, accurate, and cost-effective COVID-19 test. Using label-free microscopic imaging combined with artificial intelligence, they can detect and classify SARS-CoV-2 in under one minute.
Researchers have developed a smart dental implant that resists bacterial growth and generates its own electricity through chewing and brushing. The implant uses a nanoparticle-infused material that repels bacteria and an embedded light source powered by piezoelectric properties to conduct phototherapy.
The Center for Research on Programmable Plant Systems (CROPPS) aims to create systems that enable plants to communicate their hidden biology to sensors, optimizing growth and the local environment. This will lead to breakthrough discoveries, new educational opportunities, and transformative management of crops.
The university will acquire an optical tweezer to study colloidal copolymer chains, protein binding strength and other phenomena. The instrument will be made available to Rice researchers and collaborators.
A team of researchers is developing a smartphone-based device that can predict the size of aortic aneurysms and detect fluid overload in postpartum women. The device uses arterial waveforms, which can be easily recorded with a smartphone camera or smart scale, to provide a non-imaging solution for AA screening.
Researchers identify commercialized Membrane Distillation as a green solution for clean, drinkable water. The technique overcomes Reverse Osmosis limitations and provides safe drinking water while managing brines, keeping the environment safe.
Scientists develop robotic model of mantis shrimp strike, revealing geometric latching process behind ultra-fast movements. The device accelerates to 26 meters per second, equivalent to a car reaching 58 mph in four milliseconds.
A team of researchers has created a bioink that can reduce toxicity and improve cell survival, enabling the fabrication of clinically relevant human-scale organs. The development paves the way for regenerative medicine applications.
Princeton University researchers have created the world's smallest mechanically interlocked biological structure, a deceptively simple two-ring chain made from tiny strands of amino acids. The study demonstrates that these structures can toggle between at least two shapes, laying the groundwork for a biomolecular switch.
Researchers at Rice and Baylor are expanding their efforts to halt bone cancer metastasis using a molecule targeting osteoporosis and HER2 protein. Their goal is to improve drug concentration at tumor sites, inhibit secondary metastasis, and explore the therapeutic effect mechanism.
Researchers have developed a new way to deliver molecular therapies to cells using a programmable system called SEND, which harnesses natural proteins in the body to encapsulate and deliver different RNA cargoes. This could lead to safer and more targeted delivery of gene editing and other molecular therapeutics.
Researchers at the University of South Florida discovered that glassy polymers, or plastics, have a soft, rubbery layer on their surface that can be controlled. This breakthrough could lead to improved properties such as adhesion and scratch resistance in materials like automobile paint and cellphone screens.
Magnetomicrometry offers a new approach to controlling prosthetic limbs by measuring muscle length and speed, providing more precise control than existing methods. The technology involves inserting small magnetic beads into muscle tissue, which can be precisely measured within milliseconds.
Engineers at MIT have developed a soft, lightweight neuroprosthetic hand that enables amputees to perform daily activities with ease. The prosthetic features a system for tactile feedback, allowing users to feel sensations in their residual limb, and is potentially low-cost for low-income families.
A long-term study in Elkhorn Slough found that superabundant crabs weaken tidal creek banks, reducing marsh plant growth and increasing erosion. Reducing crab abundance led to increased salt marsh vegetation growth and enhanced sediment density.
A multidisciplinary team at KU is working with middle school teachers to develop education modules that expose students to science, psychology, and engineering design. The goal is to address barriers faced by women and minorities in the field, such as gender stereotyping and self-efficacy.
Researchers at the University of Basel developed a breath test to measure treatment success in epilepsy patients. The test provides immediate results without requiring a blood sample, allowing doctors to adjust medication quickly and precisely tailored to individual patients' needs.
Researchers simulated the hydrodynamic behavior of deep-sea Venus flower sponge E. aspergillum, revealing its skeletal adaptations optimize flow physics within and beyond its body cavity. The findings improve understanding of mechanical and biological responses to dynamic forces.
A collaboration has created a first-ever simulation of the deep-sea Venus basket sponge, revealing its ability to withstand dynamic forces and create nutrient-rich vortex within its body cavity. The structure of the sponge is optimized for fluid flow, reducing drag and facilitating feeding and reproduction.