Articles tagged with Biomedical Engineering
Researchers at Duke University have developed a new approach to building point-of-care diagnostic devices that uses gravity to transport and mix liquid droplets. The device relies on commercially available surface coatings that can tweak the wettability and slipperiness of the channels, allowing for complex fluid paths to be designed.
Scientists have found that mixtures of polymers can form phase-separated droplets, similar to lava lamps, which interact with cell membranes in unexpected ways. These interactions affect the exterior structure of cells, creating a mosaic of droplets and signaling to the outside.
Researchers developed a soft, wireless implant that monitors the heart and delivers electrical stimuli to stop atrial fibrillation. The device dissolves harmlessly in the body after a clinically relevant period, reducing healthcare costs and improving patient outcomes.
A novel hydrogel has been developed to induce endometrial regeneration and elucidate its mechanism, offering new hope for patients struggling with infertility. The gel, made from uterus-derived decellularized extracellular matrix, successfully regenerated the endometrium in mice, creating a favorable environment for embryo implantation.
Researchers create a three-dimensional epithelial model that reproduces the human lip area, allowing for evaluation of cosmetic ingredients and products. The model's structure and differentiation mode are similar to those of actual human lip tissue.
The University of Pittsburgh researcher is working on a three-year project to harness the potential of liquid-solid interaction for biomedical engineering and suspension bridge construction. The study aims to precisely control microrobots through the bloodstream and prevent disasters like the Tacoma Narrows Bridge collapse.
A research team at CityU developed a multifunctional composite polymer coating with both radiative and non-radiative cooling capacity, enhancing heat dissipation in wearable electronics. The cooling interface achieved temperature drops of over 56°C, improving the performance of skin electronic devices.
A new study from Aarhus University has found that applying AI predictions of protein structures enhances the CRISPR technology, making the cuts in a patient's DNA more precise. This discovery may lead to better treatments for patients with genetic disorders and potentially develop cures for various genetic diseases.
Scientists create optically controllable liposomes called LiDLs, which can selectively release contents inside cells upon exposure to acidic pH induced by green light. The researchers demonstrated that LiDLs efficiently deliver substances without causing side effects, showcasing exceptional extracellular stability.
Researchers at KIT have developed nanoparticles that can carry antibiotics directly to the lungs, increasing drug concentration and reducing resistance. The nanocarriers, containing Bedaquilin or BTZ-043, overcome biological barriers and show effectiveness in treating multidrug-resistant tuberculosis.
Researchers at TUM developed a new approach to measure human brain activity using microelectrodes and awake brain surgery. They found individual neurons specialize in handling specific numbers, providing insights into cognitive functions and developing solutions for brain function disorders.
A University of Arizona professor has developed a 1-minute frailty testing platform to screen patients for frailty, enabling better care decisions. The platform measures motor, heart, and brain function using wearable sensors, providing an accurate diagnosis.
A new rapid viral plaque detection system enabled by holography and deep learning can help accelerate vaccine and drug development. The system reduces the detection time of traditional viral plaque assays by up to 48 hours, eliminating chemical staining and manual counting.
Researchers created a robot inspired by pangolins' ability to curl up into a ball, with a soft layer and hard metal components. The robot can emit heat when needed and transport particles like medicines, making it promising for minimally invasive medical procedures.
Researchers developed a new method for controlling lower limb exoskeletons using deep reinforcement learning, enabling more robust and natural walking control. The system has the potential to benefit users with spinal cord injuries, multiple sclerosis, stroke, and other neurological conditions.
Researchers developed tiny nano-sized pores that can detect specific proteins in complex biological fluids, such as blood. The breakthrough enables fast and accurate disease diagnosis, potentially leading to earlier interventions and improved treatment outcomes.
Researchers have developed a biodegradable ultrasound device that can open the blood-brain barrier, allowing chemotherapy to penetrate and kill brain cancer cells. The device is as powerful as traditional ceramic-based devices and has shown promising results in animal trials.
A handheld bioprinter has been developed to address limitations of previous designs, paving the way for applications in regenerative medicine, drug development, and custom orthotics. The device's modular design allows for control over printing mixture and properties, enabling repair and regeneration of defective tissues and organs.
Recent innovations in volumetric bioprinting by UMC Utrecht researchers enable faster and more clinically relevant printing of living tissues. By controlling chemical properties, the team creates smart materials that guide cell behavior and development, mimicking native biochemical environments.
Researchers at UMC Utrecht successfully merged two printing techniques to create functional tissues made from stem cells. Granular biogels enable high cell density, survival, and specialization, surpassing solid gels. This breakthrough boosts tissue functionality and opens up opportunities for regenerative medicine.
Researchers at City University of Hong Kong developed a novel, wearable, olfaction feedback system with wireless capabilities for virtual reality. The system releases various odours using miniaturized odour generators and has been tested with an average success rate of 93 percent.
A recent study from Michigan Medicine suggests relief may be possible for individuals with tinnitus, a condition characterized by ringing or hissing sounds. The innovative bi-sensory treatment device improved quality of life and reduced tinnitus loudness in nearly 70% of participants.
A new AI model, NeCLAS, can predict how nanoparticles bind to proteins, a crucial step in designing antibiotics and antivirals. This breakthrough could help combat antibiotic-resistant infections and develop new treatments for diseases.
Researchers from Tel Aviv University and UCLA developed a method to improve memory consolidation by inducing deep-brain stimulation during sleep. The study found that precise timing of electrical stimulation enhances synchronization between the hippocampus and frontal cortex, leading to improved accuracy in recalling memories.
Scientists developed a microfluidic system to study luminal flow around villi in the small intestine, revealing diverse flow behaviors and underlying mechanisms. The device uses air-driven balloon actuators to deform intestinal tissue, generating dynamic flows that can be observed with microscopic fluorescent beads.
Biomedical engineers at UTS have developed an intervertebral disc-on-a-chip, a precision-engineered toolbox for low back pain studies. The device simulates the complex mechanobiology of native tissue, enabling accurate evaluation of experimental methods for treatment or regeneration.
A new method for producing biocompatible microfibres with controlled size and shape has been developed at Graz University of Technology, significantly accelerating production and reducing costs. This breakthrough enables the potential for accelerated production of autologous skin and organs, which could be a game-changer for burn victi...
A multidisciplinary team led by Hong Chen successfully induced a torpor-like state in mice using ultrasound, which also worked on rats. The researchers found that stimulating the hypothalamus preoptic area with ultrasound activated neurons and induced changes in body temperature and metabolism, allowing for the preservation of energy.
Researchers have developed a novel computational approach to design protein-peptide ligand binding complexes that can trigger complex cellular responses. The new biosensors can sense flexible compounds and provide optimal sensing of molecular signals, potentially leading to improved therapeutic applications.
Researchers developed a new method combining palmitoleic acid, gentamicin, and non-invasive ultrasound to improve drug delivery in chronic wounds infected with S. aureus. The strategy reduced bacterial burden by 94% and successfully sterilized wounds in diabetic mice.
A new study from UC San Diego shows that noninvasive brain imaging can distinguish among hand gestures with more than 85% accuracy. The research uses magnetoencephalography (MEG) to detect magnetic fields produced by neuronal electric currents, offering a safe and accurate option for developing brain-computer interfaces.
Researchers from University of Toronto Engineering demonstrate that bending silicone rubber medical devices can form 'microcracks' perfect for colonizing bacteria. Bacteria prefer to attach in these microscopic cracks, leading to the formation of potentially harmful biofilms.
Researchers at Washington University in St. Louis have found a way to enhance glymphatic transport using focused ultrasound with microbubbles, opening new opportunities for studying brain diseases and function. The non-invasive method shows promise for potentially mitigating neurodegenerative diseases like Alzheimer's and Parkinson's.
Researchers at Nanyang Technological University found that cells near wavy shaped wounds moved in a swirling manner, while those near straight wounds moved in straight lines. This discovery reveals that the swirling motion is crucial for gap-bridging and accelerates wound healing in wavy wounds.
A team led by Professor Timo Betz has developed a 3D cell culture chamber to grow muscle and other tissue using high-resolution microscopy. The new system will enable scientists to mimic the mechanical situations that confront various living tissues in serious conditions, reducing animal testing and costs.
Researchers developed 'smart' coatings that monitor strain on implants to prevent infection and provide early failure warning. The coatings, inspired by dragonfly and cicada wings, integrate flexible sensors with antibacterial surfaces.
The University of Southern California has launched a $1 billion-plus initiative for computing research and education, focusing on AI, machine learning, data science, and emerging technologies. The initiative aims to integrate digital literacy across disciplines and prepare students for a more tech-intensive world.
The Spitrobot simplifies sample preparation for time-resolved crystallography, allowing non-specialist groups to conduct experiments that previously required expert expertise. This technology accelerates research in enzymatic mechanisms and enables broader applications in biotechnology and disease-related problems.
Scientists have successfully regulated the flow of single molecules in a solution by opening and closing a nanovalve, which could revolutionize chemical and biochemical synthesis. This technology has the potential to detect pathogens with high sensitivity and create new materials for various industries.
A team of researchers developed a multi-organ chip on-a-chip that applies 3D cell printing technology to closely replicate the pathological environment of type 2 diabetes. The chip shows a correlation between visceral fat and T2D, as well as impaired retina cell function, indicating potential complications.
The PRISM-LT project aims to create an adaptable platform for 3D bioprinting of living tissue with dynamic functionalities and predictable shapes, using a novel tunable bioink that fosters a symbiotic relationship between stem cells and microorganisms.
Researchers at Duke University have successfully improved the resolution of Magnetic Resonance Imaging (MRI), capturing images of a mouse brain with unprecedented sharpness. The breakthrough allows for the visualization of microscopic details within the brain, enabling new insights into neurodegenerative diseases such as Alzheimer's an...
Researchers have built a new model to examine Usher Syndrome, a leading cause of combined deafness and blindness. The model replicates the visual problems not addressed by previous models, offering insight into strategies for designing therapeutic interventions.
A team of researchers has developed a method that uses electric stimulation to accelerate wound healing, making it possible for wounds to heal up to three times faster. The technique involves applying an electric field to damaged skin, which helps guide skin cells in the same direction, promoting faster healing.
A research group has successfully developed an adsorbent material that can selectively recover rare earth elements from hot spring water, a process expected to contribute to a metal resource-circulating society. The method uses environmentally friendly and inexpensive materials, such as baker's yeast and trimetaphosphate.
A multidisciplinary research team has developed a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak. The protein, Griffithsin, disables a wide range of viruses, including COVID-19, and can be manufactured without living cells.
Researchers have developed a novel 3D printing strategy that preserves the folding structure and molecular function of various biopolymers, enabling precise control over size and geometry at submicron resolution. The technique allows for the production of 3D biopolymeric architectures with functional integrity and biofunctions.
Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...
Scientists have developed a new microfluidic sperm selection device to improve IVF success rates. The device replicates the natural sperm selection process, resulting in an 85% improvement in DNA integrity and a 90% reduction in sperm cell death.
A recent study by UPF's BCN MedTech defines a computational model that simulates protein interactions to pinpoint osteoarthritis causes in each patient. This model enables personalized and efficient treatments, which are currently challenging due to the disease's multifactorial origin.
OncoMerge uses genetic data to analyze tumor activity and predict future changes. The software detects abnormal gene fusions and mutations affecting protein expression and gene copy numbers, improving the accuracy of cancer modeling predictions.
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
A research team from Pohang University of Science & Technology has engineered an artificial kidney to detect adverse drug reactions and provide personalized treatment. The team successfully fabricated a glomerular microvessel-on-a-chip that recapitulates the kidney's filtering function and evaluates its response to various toxins.
Researchers from Osaka Metropolitan University have developed a system that converts waste acetone and low CO2 concentrations into biodegradable plastic using artificial photosynthesis. The study successfully synthesized 3-hydroxybutyrate with over 60% efficiency after 24 hours.
A new method using brain signal processing has been developed to categorize different types of depression. The study achieved a 91% accuracy rate in detecting anxious and non-anxious depression, showing promise for improved diagnosis and treatment.
The new center aims to amplify biomedical research and human health applications, fostering collaboration among innovators. BRIC members will have access to resources and support for applying their nuclear physics expertise in new areas.
A team of researchers from POSTECH and Georgia Tech developed a biohybrid 3D printed heart model with integrated sensors to monitor drug-induced cardiotoxicity. The platform enables real-time, continuous monitoring of heart contractions, facilitating the testing of acute and chronic pharmacological effects.
Researchers developed innovative contrast-enhancing agents to tackle limitations of photoacoustic imaging, including low SNR, image contrast, and targeted delivery. The study suggests promising strategies such as photoswitching agents, near-infrared-II agents, and micromotor agents.
Researchers from Kessler Foundation found that transcutaneous spinal stimulation does not interfere with implanted intrathecal baclofen pump delivery systems. However, communication between the pump and its interrogator may be briefly affected due to electromagnetic interference.
Researchers at Harvard University developed a novel RNA sense-and-respond circuit, DART VADAR, which utilizes an enzyme to detect specific molecular markers of disease and cell types. This enables highly specific treatments for various diseases by triggering the translation of therapeutic genetic payloads.