Articles tagged with Biomedical Engineering
New research from Binghamton University reveals that the topography patterns of wrinkled fingers remain constant after multiple immersions. The study found that blood vessels beneath the skin contract and move in relation to other vessels, resulting in consistent wrinkles.
Researchers from The University of Osaka developed a new technique using mass photometry to detect and quantify components of rAAV particles. This method can distinguish between full and empty particles, streamlining gene therapy manufacturing and improving clinical effectiveness.
A Phase II trial demonstrates the safety and clinical benefit of PRL3-zumab, a novel humanised antibody therapy targeting PRL3 in advanced solid cancers. The treatment has shown promising results, slowing disease progression in patients with no response to existing treatments.
A study found that microRNA-27a promotes dental tissue regeneration by suppressing inflammation and activating Wnt/BMP signaling pathways. The researchers used human dental pulp stem cells to overexpress miRNA-27a, which led to the formation of new bone-like tissue in mice.
Researchers explored combining checkpoint blockade therapy with in situ vaccination to improve anti-tumor immunity in colorectal cancer. This innovative approach aims to mitigate adverse effects and enhance treatment effectiveness by targeting immune checkpoints and promoting tumor-specific T cell responses.
Researchers have discovered terahertz light waves can reduce hyperactivity in brain regions associated with depression, leading to rapid improvements in mood and thinking ability. The treatment works without introducing foreign substances into the brain and is safe for use at therapeutic intensities.
The journal is inviting submissions on AI applications in biomedical engineering, focusing on medical device development, personalized diagnostics, and patient outcome prediction. Accepted articles will be published as part of a themed section showcasing current research on AI applications in biomedical engineering.
A recent study found that fine-tuned GPT-4 chatbot can provide trustworthy information to pregnant women with opioid use disorder. The chatbot uses motivational interviewing and evidence-based guidelines to help individuals overcome resistance to change and access local treatment centers.
Scientists develop brain-computer interface that allows users to design distinct tactile experiences for different objects, enabling them to guess the object by sensation alone. The study represents an important step towards creating a neuroprosthetic that feels pleasant and intuitive to use.
Researchers have identified Clusterin as a novel marker capable of functionally categorizing aged HSCs. Clu-positive HSCs showed an increased propensity towards differentiating into platelets or myeloid cells, while Clu-negative HSCs maintained a balanced cell production approach typical of younger stages.
Researchers developed a brain decoder to restore communication between the brain and spinal cord, allowing for rehabilitation and potentially restoring movement. The decoder used electroencephalography to predict movement intention, outperforming previous methods.
The Virginia Tech Helmet Lab has released an updated set of equestrian ratings that considers impact scenarios with horizontal velocity, typically occurring in racing and cross-country events. The new ratings aim to inform consumer decisions about helmet purchasing by reflecting concussion risk associated with each model.
A new brain-inspired algorithm developed at BU can help hearing aids tune out interference and isolate single talkers in a crowd of voices. In testing, researchers found it could improve word recognition accuracy by 40 percentage points relative to current hearing aid algorithms.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.
Researchers at Princeton University developed a 'metabot' material that can expand, assume new shapes, move, and respond to electromagnetic commands. The metamaterial's complex behavior is enabled by chirality, allowing it to defy typical physical object rules.
Researchers at Carnegie Mellon University have developed a novel FRESH bioprinting technique that enables the creation of microphysiologic systems entirely out of collagen, cells, and other proteins. This advancement expands the capabilities of studying disease and building tissues for therapy, such as Type 1 diabetes.
University of Virginia researcher Natasha D. Sheybani has received a $5.5 million grant to advance her research on focused ultrasound technology for breast cancer immunotherapy. Her work aims to enhance the safety, effectiveness, and precision of immunotherapy drugs.
The journal aims to foster dialogue among disciplines such as rehabilitation, public health, and materials science to establish itself as a leading platform for scholarly exchange. Shandong University's H&R seeks to drive advancements in sustainable healthcare systems through open access publication.
A new CFD model has been proposed to optimize the green production of high-purity dimethyl carbonate (DMC) for critical industrial applications. The model reveals the dynamics of DMC crystallization and provides a balance between rapid crystal growth and higher yield.
Scientists at Nano Life Science Institute developed engineered EVs that activate immune cells inside tumors, enhancing immune responses while reducing harmful side effects. The breakthrough could lead to more targeted and effective cancer therapies with fewer side effects.
Researchers developed a novel caffeine sensor utilizing zinc-doped tin oxide nanoparticles as an electrocatalyst, demonstrating remarkable sensitivity and selectivity. The sensor successfully analyzed caffeine content in various real water samples, including tap water, groundwater, and canal water.
Researchers calculated two indicators from body composition data to examine the relationship between muscle quality and long-term care need. People with low phase angles and extracellular to intracellular water resistance ratios were found to be at high risk of becoming dependent, especially when values fell below median thresholds.
Jennifer L. West, UVA Engineering Dean and Saunders Family Professor of Engineering, has been awarded the 2025 Pierre Galletti Award for her innovative research in biomaterials and nanomedicine. Her work has led to breakthroughs in treating cancer with precision, offering new hope to patients battling hard-to-treat cancers.
Researchers developed new AI models, InstaNovo and InstaNovo+, to vastly improve accuracy and discovery in protein science. These models excel in tasks such as de novo peptide sequencing, identifying microorganisms, and discovering novel peptides, with implications for personalized medicine, cancer immunology, and beyond.
Three UVA Engineering faculty members, Scott T. Acton, Gustavo Kunde Rohde and Shannon Barker, have been named to the 2025 class of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. They are recognized for their contributions to biomedical engineering research, innovation, teaching and leadership.
This study investigates the hepatorenoprotective effects of Lepidium draba L. extracts against cyclophosphamide-induced oxidative injuries in rats. The results show that the extract reduces apoptosis and inflammation, while increasing antioxidant activities.
This study investigates the efficacy of Alpiniae oxyphyllae Fructus in reducing renal lipid deposition in diabetic kidney disease. AOF activates PPARα, promoting fatty acid oxidation and improving dyslipidemia, while also attenuating renal injury.
Researchers developed a microfluidic device to alleviate limitations of conventional blood-filtering machines used in treating hyperleukocytosis in children. The new device separates blood cells by size without platelet loss or adverse effects, enabling safe leukapheresis procedures.
Virginia Tech researchers Pamela VandeVord and Gunnar Brolinson received a $2.17 million grant to investigate cranial osteopathic manual manipulation as a potential treatment for traumatic brain injury symptoms, particularly headaches. The noninvasive technique aims to enhance brain fluid motion and balance the autonomic nervous system.
Researchers at the University of Birmingham have developed a new method for rapid scalable preparation of uniform nanostructures directly from block polymers, significantly reducing processing time from weeks to just minutes.
Engineered platelets-based nano-aircraft carriers enhance targeted chemotherapy with graded drug release, promoting antitumor immune response and reducing metastasis. Researchers successfully develop Pts-based nanovesicles for precise cancer treatment.
Researchers have discovered how cholesterol crystals form in human bodies, shedding light on heart disease and gallstones. The team identified a special solvent that mimics the body's natural environment, allowing them to watch how cholesterol crystals grow in real time.
A new method of biometric authentication has been developed using hyperspectral imaging and AI to identify individuals through the unique patterns in their blood vessels on the palm of their hand. The technology shows great promise for secure personal identification and could potentially be used as a key to unlock homes.
Researchers at Max Planck Institute have created a biorobotic arm with artificial muscles that can mimic and suppress real tremors. The technology has the potential to revolutionize assistive exoskeletons and wearable devices for individuals with tremors, providing a more discreet and effective solution.
Richard Willson, a University of Houston professor, has been elected Fellow of the Royal Society of Chemistry for his contributions to the chemical sciences. He has developed innovative methods to detect viruses and other biological threats using glow-in-the-dark nanoparticles.
Researchers developed a deep-learning framework, STAIG, to automatically map distinct genetic activity to tissue regions without manual alignment. The study demonstrates superior performance across various conditions, showcasing its potential for cancer research and understanding complex biological systems.
Scientists have uncovered ancient TIGR systems, which use RNA to guide protein modification of DNA in human cells. These compact and modular systems can target any DNA sequence with high precision, making them a promising tool for therapeutic deployment.
Researchers at the University of Malaga have identified multiple genetic variants causing Familial Chilomicronemia Syndrome, a rare disease characterized by high triglyceride levels. This discovery enables accurate clinical diagnosis and treatment selection for patients with this condition.
Ebru Demir aims to study how groups of AI-driven microswimmers move in biological fluids for potential applications in drug delivery, fertility treatments, and other medical fields. Her research combines artificial microswimmers with machine learning to uncover the underlying physics governing their movement.
The article reviews additive manufacturing technology for biomedical metals, enabling customized implants with precise internal structures. It highlights the integration of AI and 4D printing, addressing challenges in production costs, regulatory compliance, and post-processing.
Researchers developed a liquid fertilizer replacing unsustainable chemical fertilizers with organic waste, producing up to 100% of nitrogen and 77% of phosphorus. The method also increases phosphorus solubility by adjusting pH levels.
Researchers at Washington University in St. Louis have developed nature-inspired bioelectronic scaffolds for creating new tissue with electronic conductivity. The scaffolds, printed using a soft conducting hydrogel, have the properties cells need to form new tissue and offer advantages over traditional materials.
Researchers explore the connection between Alzheimer's and metabolic syndrome, finding links between insulin regulation, high blood pressure, and obesity. The study suggests that maintaining healthy blood fat levels may be crucial for brain health, paving way for potential therapeutic developments.
A new sponge-like implant helps guide a treatment that slows or stops a degenerative condition similar to multiple sclerosis. The implant attracted diseased immune cells, enabling researchers to study and target them with a nanoparticle-based treatment, which prevented mice from developing symptoms such as paralysis if administered early.
A University of Chicago team has developed a hydrogel from malva nuts that expands up to 20 times its weight when soaked in water. The gel exhibits superior performance in wound care and biomonitoring, surpassing commercial ECG patches.
Texas A&M University professors Drs. Vanderlei Bagnato, Rodney Bowersox and Don Lipkin have been elected to the National Academy of Engineering (NAE) Class of 2025 for their outstanding contributions to engineering practice, research and education. The NAE recognition underscores the exceptional talent within the faculty.
Harvard researchers have developed a silicon chip capable of recording small yet telltale synaptic signals from a large number of neurons. The chip has successfully mapped over 70,000 synaptic connections from approximately 2,000 rat neurons.
Researchers developed mini biohybrid rays using cardiomyocytes and rubber, demonstrating improved swimming efficiencies approximately two times greater than previous biomimetic designs. The application of machine-learning directed optimization enabled an efficient search for high-performance design configurations.
Researchers from Aalto University have created a synthetic surface inspired by lotus leaves and found that plastronic waves travel along the surface at speeds up to 45 times faster than capillary waves. The discovery could lead to new applications in biotechnology, materials science, and pharmaceuticals.
A new AI-based tool can translate a person's thoughts into continuous text without requiring language comprehension, and it can be trained in under an hour. The system was developed by adapting a previous brain decoder to a new person using short, silent videos.
Researchers found a high agreement between EEG and fMRI in identifying brain regions activated during language tasks. EEG-guided tDCS improved picture-naming speed in participants, suggesting its potential for innovative therapies.
Researchers discover how an anticancer drug triggers an 'outside in' signal to get sucked into a cancer cell, providing insights into adhesion regulation and potential drug design targets. The study reveals a new mechanism for delivering drugs using P-cadherin protein.
Researchers developed surface-modified apatite coatings using pH control to enhance cell adhesion and improve the biocompatibility of implants. The study found that controlling the nanoscale surface layer of apatite nanoparticles leads to better binding affinity with biological tissues.
Researchers at MIT develop CuRVE technology, enabling uniform labeling of proteins across millions of individual cells in intact 3D tissues. This breakthrough allows for unprecedented insights into cellular functions and behaviors, overcoming limitations of existing labeling methods.
A new prototype developed by the University of the Basque Country assesses and rehabilitates balance problems in patients after a stroke or due to other conditions. The device makes reliable and repeatable measurements using sensors on a platform that stimulates the patient's balance.
Elizabeth Hillman, a pioneer in imaging method development, is leading the new Department of Imaging Sciences at St. Jude Children's Research Hospital. The department aims to develop innovative new imaging and measurement approaches that will enable groundbreaking scientific studies and improve patient care.
Researchers at University of Galway have made a breakthrough in bioprinting functional human heart tissue that can change shape, bringing research closer to generating fully functional organs. The technology has shown improved structural and functional maturity of bioprinted heart tissues.
PolyU's 16 projects funded by HMRF focus on healthcare innovation, covering areas like nursing care, health tech, and biomedical engineering. The research aims to address global healthcare challenges and improve overall well-being.
Researchers have discovered a complementary regulation system between DNA and RNA epigenetics, enabling more effective gene activation. This mechanism is crucial for cell development and specialization, and could lead to advances in cancer treatments through targeted therapies.
Researchers at UVA have developed computer models to target specific bacteria in specific parts of the body, reducing the chance of antibiotic resistance. This approach could lead to more effective treatments and reduce the need for broad-spectrum antibiotics.