Articles tagged with Biomedical Engineering
Researchers developed new AI models, InstaNovo and InstaNovo+, to vastly improve accuracy and discovery in protein science. These models excel in tasks such as de novo peptide sequencing, identifying microorganisms, and discovering novel peptides, with implications for personalized medicine, cancer immunology, and beyond.
Three UVA Engineering faculty members, Scott T. Acton, Gustavo Kunde Rohde and Shannon Barker, have been named to the 2025 class of the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows. They are recognized for their contributions to biomedical engineering research, innovation, teaching and leadership.
This study investigates the hepatorenoprotective effects of Lepidium draba L. extracts against cyclophosphamide-induced oxidative injuries in rats. The results show that the extract reduces apoptosis and inflammation, while increasing antioxidant activities.
This study investigates the efficacy of Alpiniae oxyphyllae Fructus in reducing renal lipid deposition in diabetic kidney disease. AOF activates PPARα, promoting fatty acid oxidation and improving dyslipidemia, while also attenuating renal injury.
Researchers developed a microfluidic device to alleviate limitations of conventional blood-filtering machines used in treating hyperleukocytosis in children. The new device separates blood cells by size without platelet loss or adverse effects, enabling safe leukapheresis procedures.
Virginia Tech researchers Pamela VandeVord and Gunnar Brolinson received a $2.17 million grant to investigate cranial osteopathic manual manipulation as a potential treatment for traumatic brain injury symptoms, particularly headaches. The noninvasive technique aims to enhance brain fluid motion and balance the autonomic nervous system.
Researchers at the University of Birmingham have developed a new method for rapid scalable preparation of uniform nanostructures directly from block polymers, significantly reducing processing time from weeks to just minutes.
Engineered platelets-based nano-aircraft carriers enhance targeted chemotherapy with graded drug release, promoting antitumor immune response and reducing metastasis. Researchers successfully develop Pts-based nanovesicles for precise cancer treatment.
Researchers have discovered how cholesterol crystals form in human bodies, shedding light on heart disease and gallstones. The team identified a special solvent that mimics the body's natural environment, allowing them to watch how cholesterol crystals grow in real time.
A new method of biometric authentication has been developed using hyperspectral imaging and AI to identify individuals through the unique patterns in their blood vessels on the palm of their hand. The technology shows great promise for secure personal identification and could potentially be used as a key to unlock homes.
Researchers at Max Planck Institute have created a biorobotic arm with artificial muscles that can mimic and suppress real tremors. The technology has the potential to revolutionize assistive exoskeletons and wearable devices for individuals with tremors, providing a more discreet and effective solution.
Richard Willson, a University of Houston professor, has been elected Fellow of the Royal Society of Chemistry for his contributions to the chemical sciences. He has developed innovative methods to detect viruses and other biological threats using glow-in-the-dark nanoparticles.
Researchers developed a deep-learning framework, STAIG, to automatically map distinct genetic activity to tissue regions without manual alignment. The study demonstrates superior performance across various conditions, showcasing its potential for cancer research and understanding complex biological systems.
Scientists have uncovered ancient TIGR systems, which use RNA to guide protein modification of DNA in human cells. These compact and modular systems can target any DNA sequence with high precision, making them a promising tool for therapeutic deployment.
Researchers at the University of Malaga have identified multiple genetic variants causing Familial Chilomicronemia Syndrome, a rare disease characterized by high triglyceride levels. This discovery enables accurate clinical diagnosis and treatment selection for patients with this condition.
Ebru Demir aims to study how groups of AI-driven microswimmers move in biological fluids for potential applications in drug delivery, fertility treatments, and other medical fields. Her research combines artificial microswimmers with machine learning to uncover the underlying physics governing their movement.
The article reviews additive manufacturing technology for biomedical metals, enabling customized implants with precise internal structures. It highlights the integration of AI and 4D printing, addressing challenges in production costs, regulatory compliance, and post-processing.
Researchers developed a liquid fertilizer replacing unsustainable chemical fertilizers with organic waste, producing up to 100% of nitrogen and 77% of phosphorus. The method also increases phosphorus solubility by adjusting pH levels.
Researchers at Washington University in St. Louis have developed nature-inspired bioelectronic scaffolds for creating new tissue with electronic conductivity. The scaffolds, printed using a soft conducting hydrogel, have the properties cells need to form new tissue and offer advantages over traditional materials.
Researchers explore the connection between Alzheimer's and metabolic syndrome, finding links between insulin regulation, high blood pressure, and obesity. The study suggests that maintaining healthy blood fat levels may be crucial for brain health, paving way for potential therapeutic developments.
A new sponge-like implant helps guide a treatment that slows or stops a degenerative condition similar to multiple sclerosis. The implant attracted diseased immune cells, enabling researchers to study and target them with a nanoparticle-based treatment, which prevented mice from developing symptoms such as paralysis if administered early.
A University of Chicago team has developed a hydrogel from malva nuts that expands up to 20 times its weight when soaked in water. The gel exhibits superior performance in wound care and biomonitoring, surpassing commercial ECG patches.
Texas A&M University professors Drs. Vanderlei Bagnato, Rodney Bowersox and Don Lipkin have been elected to the National Academy of Engineering (NAE) Class of 2025 for their outstanding contributions to engineering practice, research and education. The NAE recognition underscores the exceptional talent within the faculty.
Harvard researchers have developed a silicon chip capable of recording small yet telltale synaptic signals from a large number of neurons. The chip has successfully mapped over 70,000 synaptic connections from approximately 2,000 rat neurons.
Researchers developed mini biohybrid rays using cardiomyocytes and rubber, demonstrating improved swimming efficiencies approximately two times greater than previous biomimetic designs. The application of machine-learning directed optimization enabled an efficient search for high-performance design configurations.
Researchers from Aalto University have created a synthetic surface inspired by lotus leaves and found that plastronic waves travel along the surface at speeds up to 45 times faster than capillary waves. The discovery could lead to new applications in biotechnology, materials science, and pharmaceuticals.
A new AI-based tool can translate a person's thoughts into continuous text without requiring language comprehension, and it can be trained in under an hour. The system was developed by adapting a previous brain decoder to a new person using short, silent videos.
Researchers found a high agreement between EEG and fMRI in identifying brain regions activated during language tasks. EEG-guided tDCS improved picture-naming speed in participants, suggesting its potential for innovative therapies.
Researchers discover how an anticancer drug triggers an 'outside in' signal to get sucked into a cancer cell, providing insights into adhesion regulation and potential drug design targets. The study reveals a new mechanism for delivering drugs using P-cadherin protein.
Researchers developed surface-modified apatite coatings using pH control to enhance cell adhesion and improve the biocompatibility of implants. The study found that controlling the nanoscale surface layer of apatite nanoparticles leads to better binding affinity with biological tissues.
Researchers at MIT develop CuRVE technology, enabling uniform labeling of proteins across millions of individual cells in intact 3D tissues. This breakthrough allows for unprecedented insights into cellular functions and behaviors, overcoming limitations of existing labeling methods.
A new prototype developed by the University of the Basque Country assesses and rehabilitates balance problems in patients after a stroke or due to other conditions. The device makes reliable and repeatable measurements using sensors on a platform that stimulates the patient's balance.
Elizabeth Hillman, a pioneer in imaging method development, is leading the new Department of Imaging Sciences at St. Jude Children's Research Hospital. The department aims to develop innovative new imaging and measurement approaches that will enable groundbreaking scientific studies and improve patient care.
Researchers at University of Galway have made a breakthrough in bioprinting functional human heart tissue that can change shape, bringing research closer to generating fully functional organs. The technology has shown improved structural and functional maturity of bioprinted heart tissues.
PolyU's 16 projects funded by HMRF focus on healthcare innovation, covering areas like nursing care, health tech, and biomedical engineering. The research aims to address global healthcare challenges and improve overall well-being.
Researchers have discovered a complementary regulation system between DNA and RNA epigenetics, enabling more effective gene activation. This mechanism is crucial for cell development and specialization, and could lead to advances in cancer treatments through targeted therapies.
Researchers at UVA have developed computer models to target specific bacteria in specific parts of the body, reducing the chance of antibiotic resistance. This approach could lead to more effective treatments and reduce the need for broad-spectrum antibiotics.
A team led by University of Rochester professor Edmund Lalor aims to understand how the brain processes audiovisual information to improve speech comprehension for individuals with cochlear implants. They will use noninvasive electroencephalography (EEG) brainwave measurements to study how people respond to multisensory speech.
The American Physical Society's joint March Meeting and April Meeting will convene more than 14,000 physicists from around the world to present new research in various fields. The conference will be held in person in Anaheim, California and online everywhere March 16-21.
Scientists have identified the crucial role of weak molecular interactions in triggering autophagy, a process that breaks down unnecessary cell components. By artificially controlling these interactions, researchers aim to improve the degradation of aggregates in neurodegenerative diseases and enhance cancer treatments.
The study introduces Flexible-Spoke, Non-Pneumatic Tyres as a solution for manual wheelchair users. These tyres absorb impacts and vibrations, offering enhanced comfort and reduced weight compared to conventional options.
Researchers develop PSO-BP neural network to predict CO₂ hazard distance after pipeline rupture, reducing computational demands. The model is consistent with CO₂ concentration diffusion results.
Researchers developed a non-invasive way to assess fat composition around the heart using magnetic resonance imaging. This technique may help doctors identify patients at greatest risk for cardiac problems and predict treatment outcomes.
Researchers at Texas A&M University have uncovered a mechanism behind cancer progression: the stiffening of tumor cell's environment. This spreading causes increased cell proliferation and tumor growth.
Researchers have identified molecular changes that occur long before symptoms appear, shedding light on the development of Rett syndrome. These findings hold promise for developing safe gene therapies and monitoring biomarkers to track MECP2 gene function.
A study led by Henry J. Pownall and Khurram Nasir found a strong link between the amount of free cholesterol in HDL and its accumulation in macrophages, which can contribute to heart disease. The researchers aim to develop new diagnostics and treatments for managing heart disease using HDL-free cholesterol as a biomarker.
A University of Pittsburgh study uses life-cycle assessment to measure the environmental impact of ACL reconstruction and identify opportunities for reduction. The investigation highlights the significant carbon footprint of complex medical processes, emphasizing the need for sustainable innovations in healthcare.
Researchers at the University of Massachusetts Amherst designed a novel device that manipulates cell behavior by precisely modulating the pH of the cell's environment in real-time. The device was able to manipulate pH with a resolution of 0.1 pH units, far exceeding previous electrode-based attempts.
A QUT-led study found that surgeons are slow to adopt newly developed biomaterials or tissue-engineered solutions for treating bone defects. The researchers surveyed 337 surgeons and 99 scientists, revealing a significant gap between their optimism about future advancements and the slow adoption of these innovations in clinical practice.
Recent studies highlight conductive hydrogels as solutions in biosignal monitoring and electrical stimulation. Their tunable mechanical and electrical characteristics enable a wide range of applications, including wearable sensors, neural interfaces, and drug delivery systems.
Researchers created an advanced computational model to optimize maternal vaccine design and protect high-risk populations. The model helps reveal which antibodies can pass through effectively and when, enabling the development of safer, more effective vaccines.
A team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia by mapping what happens in different brain regions during that moment. The study found that rapid activity in the medial prefrontal cortex, hippocampus, and thalamus triggers loss of consciousness.
Researchers developed a new approach to engineer tissue structures across multiple scales, from small cells to large organs. They used gallium as a molding material, allowing them to create complex vascular and interwoven networks that mimic natural biological systems.
Researchers at TUM have grown tumor organoids that reproduce the morphological complexity of pancreatic cancer cells in the laboratory. The team used machine learning to categorize the organoids into different phenotypes based on their appearance and behavior, which react differently to treatments.
Silvia Blemker, a University of Virginia biomedical engineer, has been elected Fellow of the National Academy of Inventors (NAI) for her work on muscle health. Her patented technology, Image-based Identification of Muscle Abnormalities, uses advanced imaging and analytics to provide detailed insights into muscle health.
The InteReg project aims to create interactive biomaterials that instruct cells to regenerate after brain or spinal cord injuries, potentially treating MS and other neurological disorders. The project, funded by the Carl Zeiss Foundation, brings together experts in biology, chemistry, medicine, and polymer research.
Researchers develop innovative hybrid control strategy to improve product yields in biosynthetic processes. The new approach combines model-based optimization with in-cell feedback control, outperforming traditional methods and promising reduced costs and environmental impact.
Researchers at Harvard University have developed a tissue-anchoring mechanism for medical devices, inspired by the circular hook-like attachment organ found in intestinal tapeworms. The device can be deployed in under 1 millisecond and anchors into soft tissue with minimal damage.
Researchers develop ultrasound-based method to control cell growth and orientation in cultured muscle cells. The technique uses ultrasonication to promote differentiation of myoblasts into myotubes, offering a promising alternative to current methods.
Researchers developed a microfluidic chip that can measure memory B cells' binding affinity to flu virus, helping track immunity. The device, Shear Activated Cell Sorting (SACS), can compare how well cells bind to original and new variants.