Articles tagged with Biomedical Engineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The latest SLAS Technology issue highlights recent breakthroughs in skin cutaneous melanoma, glycan-bead coupling, and acoustic ejection mass spectrometry. Researchers adapt technological advancements for life sciences exploration and experimentation in biomedical research and development.
Researchers develop an in vitro model to study tau aggregation, a process linked to neurodegenerative diseases like Alzheimer's and frontotemporal dementia. The approach offers a short timeline for generating data and facilitates the study of potential therapeutic interventions.
Researchers developed adhesive hydrogel coatings that eliminate fibrosis, a common issue with medical implants. The coatings bind devices to tissue and prevent the immune system from attacking them.
Researchers at Osaka Metropolitan University have discovered that plasma irradiation can accelerate tendon repair, showing faster regeneration and increased strength in lab rats. This breakthrough could lead to shorter treatment times and more reliable tendon healing for athletes and individuals with sports-related injuries.
Researchers designed a regenerative medicine therapy to speed up diabetic wound repair using tiny fat particles loaded with genetic instructions. The treatment targeted problem-causing cells and reduced swelling, promoting faster and more effective wound closure.
A new study published in Nature Biomedical Engineering shows that targeted cancer treatment using antibody-displaying extracellular vesicles reduces tumour growth and improves survival in mice. The treatment has the potential to be used against other diseases and cancer types, offering a more effective and fewer side effects compared t...
A new study shows that gene therapy delivered by nanocarriers can repair damaged discs and reduce signs of back pain in mice. The treatment, which uses naturally derived nanocarriers to deliver genetic material for a protein key to tissue development, restored structural integrity and function to degenerated discs.
A Japanese research team used machine-learning-driven modular assembly systems to create a more efficient gene editing tool. The study demonstrated an improvement in genome editing efficiency by 5%, showcasing the effectiveness of engineering zinc-finger nucleases through structural modeling.
Researchers from Wyss Institute and Harvard University developed a biomaterial vaccine that enhances and sustains lymph node expansion, leading to more effective anti-tumor responses. The vaccine formulation, based on microscale mesoporous silica rods, reprograms antigen-presenting cells to orchestrate complex immune responses.
Researchers at Princeton University and North Carolina State University have combined ancient paperfolding and modern materials science to create a soft robot that can bend and twist through mazes with ease. The new design allows the flexible robot to crawl forward and reverse, pick up cargo and assemble into longer formations.
The Multifunctional Ablative Gastrointestinal Imaging Capsule (MAGIC) combines OCT technology with an endoscope camera and ablation laser for superior esophageal imaging. It provides unmatched accuracy in detecting early lesions, enabling potential ablative treatment of esophageal abnormalities.
A team of researchers has developed a hemostasis sponge that swiftly staunchs kidney bleeding and facilitates wound recovery. The material uses kidney-derived decellularized extracellular matrix to recreate the kidney's microenvironment, boasting high biocompatibility.
Scientists at DTU and Lund University have found new enzymes that can remove both the A and B blood antigens and their blocking sugars, enabling the production of universal donor blood. This breakthrough has the potential to reduce logistics and costs associated with storing four different blood types.
Scientists have developed mini-colon tissues that can simulate the complex process of tumorigenesis outside the body with high fidelity. These miniature organs mimic the physical structure and cellular diversity of colon tissue, allowing researchers to study colorectal cancer development and test potential therapies.
A flexible microdisplay device can track and display neural activity in the brain, allowing neurosurgeons to visualize critical cortical boundaries and guide surgical interventions. The device reduces the need for a buffer zone, enabling more precise removal of harmful tissue.
Researchers increased EMG signal dimensions virtually to capture richer information about user intentions, improving gesture recognition accuracy. This approach leverages implicit coordination between muscles during movement, enhancing the control effect of prosthetic hands.
Researchers developed a new treatment method using plasma irradiation to speed up bone healing. The study found that displaced fractures exhibited stronger unions than nonirradiated ones, with strength increased by 3.5 times.
Synthetic platelets made of hydrogel nanoparticles mimic the size and shape of human platelets, promoting clotting and healing. The innovative device has shown promising results in animal models and is being developed for clinical use to treat various medical conditions.
Researchers detected multifractality in electrical brain signals of patients with early-stage multiple sclerosis, suggesting complex communication between neurons. The study also found that healthy individuals have more regular fractal components, indicating a potential compensatory mechanism in the brain's neural networks.
Researchers create universal method for creating wearable electronics with increased sweat permeability, enabling reliable long-term monitoring of biosignals. The device allows for continuous and stable monitoring of vital signs without signal disruption from perspiration.
Caterpillars of the Carolina sphinx moth have an extraordinary ability to instantly change their hemolymph's material properties, turning it into a viscoelastic fluid that helps stop bleeding. This discovery has potential applications for developing new drugs for humans to create fast-working thickeners of human blood.
A team of scientists from CU Boulder, Anschutz Medical Campus and CSU is developing non-invasive therapies for osteoarthritis, including a healing shot and annual infusion. They hope to begin trials in human patients within 3.5 years.
Physicists have developed FreeDTS, a modeling software that enables the study of biological membranes at the mesoscale. This tool will enhance our understanding of cell behavior and open routes for diagnostics of infections and diseases. The software's precision will guide experiments with accuracy, potentially leading to diagnoses bas...
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins. The study identified over 600 new effector proteins that could be used therapeutically, including those that can efficiently degrade or stabilize target proteins.
Researchers at Duke University have developed a novel imaging platform to visualize the growth of the placenta throughout pregnancy. The approach provides detailed images of blood flow and oxygen metabolism, shedding light on how lifestyle factors and health complications affect placental development.
Artificial intelligence has been developed to spot COVID-19 features in lung ultrasound images, combining computer-generated images with real scans to identify signs of disease. The tool holds potential for developing wearables that track illnesses like congestive heart failure and monitor fluid buildup in patients' lungs.
A multi-institutional team is creating innovative technologies to reduce complications associated with left ventricular assist devices (LVADs), including infection, thrombosis, stroke, and bleeding. The new LVAD will deliver a physiological response to changes in the recipient's activity levels using a 'smart' Maglev drive technology.
A new multitasking substance has been identified to prevent and treat both flu and COVID-19 infections concurrently. The long-acting recombinant cytokine protein rhIL-7-hyFc demonstrated therapeutic and preventive effects against various respiratory diseases, including COVID-19, influenza virus, and respiratory syncytial virus.
Researchers at Rensselaer Polytechnic Institute have developed a patented process to produce heparin in the lab, offering a consistent and safe supply of the essential medicine. The discovery has the potential to revolutionize the production of heparin, reducing reliance on animal-derived sources and addressing global supply chain issues.
Researchers at the University of Rochester are developing a multimodal, non-invasive method to study the brain's physiology and reduce neurological issues associated with ECMO therapy. The technique uses electroencephalography, diffuse correlation spectroscopy, and evoked potentials to monitor blood flow and neural activity in the brain.
Researchers aim to address LVAD shortcomings, reducing blood damage and clotting risk through innovative designs and coatings. A novel flexible stented blood inlet and slippery hydrophilic coatings will be used to prevent flow stasis and clot formation.
Researchers at Duke University found that cooperative growth in bacterial colonies can lead to the emergence of 'cheating' bacteria that exploit others. The study demonstrates how environmental pressures can shape the evolution of microbial communities.
Researchers have developed an injectable hydrogel that mitigates damage to the right ventricle of the heart in children with hypoplastic left heart syndrome. The treatment, made from cardiac extracellular matrix, improves heart function and slows tissue scarring, potentially increasing patient survival time.
Researchers at UNSW Sydney have developed a new technology offering test strips for rapid, on-the-spot disease detection. The test strips are accurate and cost-effective, making them suitable for various applications including public health, environmental diagnostics, and cancer cell detection.
Researchers developed protein-based microcapsules to enhance aptamer sensors, enabling direct detection of target molecules in biological samples. The system demonstrates robust protection against harmful proteins and simultaneous real-time sensing of multiple targets.
A new study highlights the contributions of 50 top scientists from elite universities to transforming medicine through cutting-edge biomedical engineering advances. Five primary medical challenges are identified, including precision engineering for personalized care and tissue engineering for human health.
A study by the University of Tsukuba found that keratin microsphere gel enhanced cell proliferation and gene expression related to hair growth. The gel's stimulatory impact on papilla cells was validated through genetic analysis, demonstrating its potential as a safe and effective hair growth agent.
A study by 50 experts reveals five cutting-edge biomedical engineering advances with significant applications in medicine, including precision engineering, on-demand tissue engineering, and advanced brain interface systems. These advances aim to transform the practice of medicine, impacting various conditions and diseases.
A consortium of 50 renowned researchers from 34 prestigious universities identifies five primary medical challenges that can be addressed with advanced biomedical engineering approaches, aiming to improve human health. The paper outlines a roadmap for groundbreaking research and funding to achieve technological and medical breakthroughs.
Scientists have developed a new way to alter the DNA of bacterial cells using high-frequency radio waves, outperforming traditional industry techniques. The process shows high efficiency and gentleness, with 91% of E. coli cells taking on the DNA after just three minutes.
Researchers identify five grand challenges in biomedical engineering to address social needs, existing gaps, and technological limitations. The Convergence Revolution and Fourth Industrial Revolution are expected to shape the future of medicine, emphasizing interdisciplinary collaborations and next-generation training.
A new roadmap has been published by IEEE EMBS, outlining five primary medical challenges that need to be addressed through advanced biomedical engineering approaches. The paper, written by 50 renowned researchers from 34 prestigious universities, aims to guide future research and funding for groundbreaking innovations.
Researchers from Tokyo Institute of Technology developed an ultraviolet laser-processing technique for fabricating complex microstructures, enabling the creation of biohybrid actuators capable of complex, flexible movements. The method involves forming curved microgrooves on a substrate and aligning muscle cells in an anisotropic manne...
A team of researchers has developed a bilayer nanofiber membrane hemostat using natural proteins derived from mussels and silkworm cocoons. The hemostatic agent demonstrated rapid acceleration of tissue adhesion and hemostasis in bleeding wounds, preventing the infiltration of water containing infectious agents.
Researchers at ETH Zurich developed biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation. The bio-inspired approach enabled prosthetic legs to evoke natural sensations, allowing amputees to walk faster and with greater confidence.
A new method uses digital DNA melting analysis to detect pathogens in blood samples, producing results in under six hours and reducing false positives compared to traditional blood cultures. This technology has the potential to save lives by accurately diagnosing sepsis, a leading cause of death worldwide.
Researchers create a simple method to instantly bond layers made of the same or different types of hydrogels using a thin film of chitosan. The new approach has potential to broadly advance new biomaterials solutions for multiple unmet clinical needs, including regenerative medicine and surgical care.
A recent study used AI trained on cell-to-cell communication networks to predict drug responsiveness in immunotherapy for cancer. The model demonstrated high accuracy in analyzing samples from 700 patients with four types of cancer, identifying key communication pathways related to responsiveness and resistance.
A new study finds that Type 2 diabetes causes intervertebral discs to become stiffer and change shape earlier than normal. This leads to a compromised ability to withstand pressure, highlighting the need for preventative and therapeutic strategies.
Researchers at Aston University have discovered that aging skin exhibits distinct optical properties under polarised laser light. This finding could lead to the development of non-invasive light-based techniques for early detection and monitoring of skin conditions, including cancer.
A temperature-sensitive prosthetic limb has been developed to improve amputee interactions and feelings of human connection. Researchers have created a device called MiniTouch that provides realistic and real-time thermal feedback, enabling amputees to discriminate between objects of different temperatures and materials.
The Vilcek Foundation has awarded $250,000 to four immigrant scientists for their pioneering work in biomedical science. Luciano Marraffini, Gerta Hoxhaj, Tomasz Nowakowski, and Takanori Takebe are recognized for their contributions to cancer research, pluripotent stem cells, and CRISPR-Cas systems.
University of Texas at Dallas researchers have developed a first-of-its-kind, handheld electrochemical sensor that can accurately detect fentanyl in urine within seconds. The device detects even trace amounts of fentanyl with 98% accuracy and could be used to test for the drug in saliva, helping first responders make treatment decisions.
A team of researchers from Harvard and Texas developed a soft implantable device with dozens of sensors to record single-neuron activity stably for months. The device uses fluorinated elastomers and is 10,000 times softer than conventional flexible probes.
Princeton researchers create a system to control the growth of microtubule branches, enabling precise chemical transport and potential applications in soft robotics, new medicines, and biomolecular transport. The technique harnesses cellular scaffolding to build novel materials and technologies.
A team of researchers has devised a method to deliver mRNA into the brain using lipid nanoparticles, offering new hope for treating conditions like Alzheimer's disease and seizures. The approach uses a special keycard-like system to bypass the blood-brain barrier, allowing therapeutic agents to enter the brain and target specific cells.
New biomarkers have been discovered to improve the diagnosis and monitoring of lupus nephritis, a severe manifestation of systemic lupus erythematosus. The study identified six novel urine biomarkers that can detect even low concentrations of proteins in the urine.
A team of researchers created a 3D bioprinted brain blood vessel model to investigate the impact of blood vessel curvature on metastatic cancer development. The model revealed that increased blood vessel curvature correlates with heightened cancer cell adherence and extravasation.
Researchers at Duke University developed an adaptive deep brain stimulation therapy for Parkinson's disease, targeting two key brain structures and using a novel self-adjusting device. The study found that this approach improved motor symptoms and reduced medication doses in six patients.
A team of researchers has created artificial small-diameter vessels (SDVs) featuring pores that enable the formation of an endothelium without additional processing steps. The 3D-printed vessels were successfully infused with human cells, demonstrating spontaneous cellular assembly and paving the way for potential transplantation and f...