Articles tagged with Biomedical Engineering
Researchers developed an intelligent biosensing platform based on luminescent nanoparticles and a microfluidic biochip with machine vision algorithm analysis for efficient tumor marker detection. The platform offers high sensitivity, noninvasive sampling, and portable design for early cancer screening and monitoring.
The Berggren Center for Quantum Biology and Medicine will merge quantum technology with biology to transform medicine, driving the development of revolutionary quantum tools and cultivating bilingual scholars. Researchers will translate quantum advances into clinical solutions, enabling new diagnostics and therapies.
Researchers at the Henryk Niewodniczanski Institute of Nuclear Physics have developed wound dressings containing the antibacterial drug metronidazole, which can be released in a controlled manner. The mats are made from electrospun polymer fibers and could potentially be used to treat infections.
Scientists replace toxic additives in hydrogels with D-sorbitol, a safe sugar alternative found in chewing gum, to create bioelectronic devices that are soft, safe, and integrated with natural tissue. The new material has increased biocompatibility and improved electronic performance.
Researchers engineered human spleen into bioreactor capable of curing diabetes and growing functional organs. The spleen's unique structure hosts billions of transplanted cells and provides a nutrient-rich environment for cell growth.
Researchers developed a new method to study mechanical proteins, revealing that disrupting protein titin causes muscle disease. The technique allows for targeted analysis of protein mechanics, paving the way for new therapeutic strategies.
Researchers at UH found cells can detect weak electric fields due to active matter in the cell membrane. This discovery could lead to breakthroughs in medical devices, biosensors, and disease therapies.
Researchers developed self-propelled ferroptosis nanoinducers to enhance cancer therapy by inducing programmed cell death. The nanotherapeutics exhibited enhanced diffusion and deep tumor penetration while maintaining biocompatibility.
Researchers developed stable MXene-coated contact lenses providing enhanced protection against electromagnetic radiation. The lenses exhibited a rapid temperature rise when exposed to microwave heating, indicating strong EMR absorption and dissipation.
Researchers used breath analysis to monitor general anesthesia in children, achieving results comparable to blood tests. The method also detected oxidative stress and potential complications, enabling early detection and prevention.
Researchers use MRI and NASA-inspired negative-pressure pants to improve stress tests, revealing hidden heart issues. The technology transforms heart imaging, making it possible to detect real differences in heart performance.
Researchers developed LUCAS, a rapid and portable diagnostic tool that creates stronger and longer-lasting bioluminescence signals, enabling accurate detection of SARS-CoV-2, HIV, HBV, and HCV in patient samples. The tool achieved an average accuracy of over 94% in detecting viruses within 23 minutes.
A Virginia Tech professor has received a proof-of-concept grant to further develop a chemical compound that could help promote weight loss by increasing mitochondrial activity. The compound, named BAM15, shows promise in preclinical studies without affecting food intake or muscle mass.
The article discusses recent advancements in pipeline safety technologies, including defect detection, environmental risks monitoring, and structural integrity assessment. The integration of high-grade steel, large-diameter pipelines, and unconventional energy sources has introduced new complexities to pipeline safety.
Dr. Natalie Artzi joins the Wyss Institute as Associate Institute Director, working closely with Don Ingber to shape strategic direction and advance research and translation efforts. She leads a world-class research program focused on developing tissue- and cell-responsive nanostructures for disease tracking and treatment.
Researchers at Virginia Tech's Fralin Biomedical Research Institute developed a peptide therapy called JM2 that targets cancer cells' ability to renew and regrow. The treatment significantly slows tumor growth in animal models and disrupts the maintenance of treatment-resistant cancer cells.
Texas A&M University researchers have developed a customizable vessel-chip method that can mimic various blood vessel structures, enabling more accurate models of vascular disease. The chip technology enables patient-specific research and pharmaceutical testing, with the potential to cure vascular diseases.
Researchers developed a metalens-based microscope that achieves both wide field of view and high-resolution imaging in a compact design. The system uses a doublet configuration and annular illumination to overcome traditional metalens limitations, enabling practical applications in biomedical imaging.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
Researchers at TU Wien have developed a method to create artificial blood vessels using ultrashort laser pulses, enabling the creation of mini organ models with precise control and reproducibility. The technology has been successfully applied to liver tissue models, resulting in improved metabolic activity and adequate nutrient supply.
The COLD-TUG test measures the time required for prosthetic donning and mobility in lower-limb amputation patients. Researchers found that patients with bone-anchored prostheses can don their prosthesis significantly faster, saving up to 61 seconds per session.
A Johns Hopkins Medicine study finds that SARS-CoV-2 corrupts white blood cells, specifically neutrophils, to impair the production of immune cells critical for fighting COVID-19. This reprogramming may lead to severe COVID cases by weakening the immune response against the virus.
The new 3D-printed device, STOMP, enhances tissue-engineering methods by allowing for precise control over cell types and spatial arrangement. This enables scientists to model complex diseases and recreate natural habitats of cells, paving the way for advancements in biomedical research.
A joint research team from POSTECH and Hanyang University developed a personalized stimulation control mechanism using evoked compound action potential feedback mechanisms to treat urinary disorders. This technology enables precise adjustment of tibial nerve stimulation in real-time, based on individual nerve responses, improving patie...
Researchers discovered a DNA switch in TB bacteria that regulates growth and gene expression. By targeting this process, new antibiotics could be developed to make the bacteria easier to eliminate.
Seven Clusters of Excellence at LMU Munich have been approved for funding, covering a broad range of fields from systems neurology to quantum science. The successful clusters reflect the university's exceptional commitment and cooperation with partners.
Triboelectric and piezoelectric nanogenerators convert mechanical energy into electrical energy, enhancing robotic autonomy and efficiency. The technology has the potential to reshape future robotic capabilities, particularly in industrial automation, healthcare, and smart home applications.
A study led by Johns Hopkins Medicine found a genetic mutation, F722fs, in the MMS22L gene that is associated with a higher risk of prostate cancer. The researchers identified this mutation in Ashkenazi Jewish men and found it was linked to increased sensitivity to a specific anticancer therapy.
Researchers at Rice University have developed a novel personalized medicine approach for addressing movement impairments. The Neuromusculoskeletal Modeling (NMSM) Pipeline software allows clinicians to work in collaboration to construct personalized computer models of individual patients, leading to more effective orthopedic surgery, p...
A new AI system, MedGaze, is designed to emulate how radiologists visually interpret chest X-rays. By replicating expert attention, it helps train future specialists and improve the efficiency of hospitals through better workflow management.
UT Dallas bioengineers have created an enhanced light-activated immunotherapy approach to target advanced stomach cancer. Lab-designed molecules are primed with far-red or near-infrared light to activate the immune system against stubborn cancer cells, reducing side effects.
Researchers at Boston University School of Medicine discovered that PAX3 mainly uses its paired domain to bind to DNA and turn on genes promoting cell growth and survival. The study suggests that targeting the paired domain of PAX3 could be an effective way to treat melanoma.
A new study describes a promising new type of auditory brainstem implant that could benefit people who are deaf due to NF2 and other severe inner ear abnormalities. The soft, flexible implant bypasses damaged auditory structures and directly stimulates the brainstem's sound-processing region.
A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.
Researchers analyzed data from a wearable device to find that women's physical activity levels are less variable and more predictable than men's. The study also found no significant difference in physical activity levels between individuals with and without menstrual cycles.
The University of Utah is partnering with XPRIZE to improve healthy aging through a 7-year, $101 million global competition. The partnership aims to validate the science of competing teams working towards extending health spans for aging populations.
Researchers at Brown University developed targeted liposomes that dramatically increased drug effectiveness against fungal infections, even those caused by tough-to-treat biofilms. The approach also appears to be generally safe, showing no toxicity to human cells commonly affected during infection.
New research from Binghamton University reveals that the topography patterns of wrinkled fingers remain constant after multiple immersions. The study found that blood vessels beneath the skin contract and move in relation to other vessels, resulting in consistent wrinkles.
Researchers from The University of Osaka developed a new technique using mass photometry to detect and quantify components of rAAV particles. This method can distinguish between full and empty particles, streamlining gene therapy manufacturing and improving clinical effectiveness.
A Phase II trial demonstrates the safety and clinical benefit of PRL3-zumab, a novel humanised antibody therapy targeting PRL3 in advanced solid cancers. The treatment has shown promising results, slowing disease progression in patients with no response to existing treatments.
A study found that microRNA-27a promotes dental tissue regeneration by suppressing inflammation and activating Wnt/BMP signaling pathways. The researchers used human dental pulp stem cells to overexpress miRNA-27a, which led to the formation of new bone-like tissue in mice.
Researchers explored combining checkpoint blockade therapy with in situ vaccination to improve anti-tumor immunity in colorectal cancer. This innovative approach aims to mitigate adverse effects and enhance treatment effectiveness by targeting immune checkpoints and promoting tumor-specific T cell responses.
Researchers have discovered terahertz light waves can reduce hyperactivity in brain regions associated with depression, leading to rapid improvements in mood and thinking ability. The treatment works without introducing foreign substances into the brain and is safe for use at therapeutic intensities.
The journal is inviting submissions on AI applications in biomedical engineering, focusing on medical device development, personalized diagnostics, and patient outcome prediction. Accepted articles will be published as part of a themed section showcasing current research on AI applications in biomedical engineering.
A recent study found that fine-tuned GPT-4 chatbot can provide trustworthy information to pregnant women with opioid use disorder. The chatbot uses motivational interviewing and evidence-based guidelines to help individuals overcome resistance to change and access local treatment centers.
Scientists develop brain-computer interface that allows users to design distinct tactile experiences for different objects, enabling them to guess the object by sensation alone. The study represents an important step towards creating a neuroprosthetic that feels pleasant and intuitive to use.
Researchers have identified Clusterin as a novel marker capable of functionally categorizing aged HSCs. Clu-positive HSCs showed an increased propensity towards differentiating into platelets or myeloid cells, while Clu-negative HSCs maintained a balanced cell production approach typical of younger stages.
A new brain-inspired algorithm developed at BU can help hearing aids tune out interference and isolate single talkers in a crowd of voices. In testing, researchers found it could improve word recognition accuracy by 40 percentage points relative to current hearing aid algorithms.
Researchers developed a brain decoder to restore communication between the brain and spinal cord, allowing for rehabilitation and potentially restoring movement. The decoder used electroencephalography to predict movement intention, outperforming previous methods.
The Virginia Tech Helmet Lab has released an updated set of equestrian ratings that considers impact scenarios with horizontal velocity, typically occurring in racing and cross-country events. The new ratings aim to inform consumer decisions about helmet purchasing by reflecting concussion risk associated with each model.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.
Researchers at Carnegie Mellon University have developed a novel FRESH bioprinting technique that enables the creation of microphysiologic systems entirely out of collagen, cells, and other proteins. This advancement expands the capabilities of studying disease and building tissues for therapy, such as Type 1 diabetes.
Researchers at Princeton University developed a 'metabot' material that can expand, assume new shapes, move, and respond to electromagnetic commands. The metamaterial's complex behavior is enabled by chirality, allowing it to defy typical physical object rules.
University of Virginia researcher Natasha D. Sheybani has received a $5.5 million grant to advance her research on focused ultrasound technology for breast cancer immunotherapy. Her work aims to enhance the safety, effectiveness, and precision of immunotherapy drugs.
The journal aims to foster dialogue among disciplines such as rehabilitation, public health, and materials science to establish itself as a leading platform for scholarly exchange. Shandong University's H&R seeks to drive advancements in sustainable healthcare systems through open access publication.
A new CFD model has been proposed to optimize the green production of high-purity dimethyl carbonate (DMC) for critical industrial applications. The model reveals the dynamics of DMC crystallization and provides a balance between rapid crystal growth and higher yield.
Scientists at Nano Life Science Institute developed engineered EVs that activate immune cells inside tumors, enhancing immune responses while reducing harmful side effects. The breakthrough could lead to more targeted and effective cancer therapies with fewer side effects.
Researchers developed a novel caffeine sensor utilizing zinc-doped tin oxide nanoparticles as an electrocatalyst, demonstrating remarkable sensitivity and selectivity. The sensor successfully analyzed caffeine content in various real water samples, including tap water, groundwater, and canal water.
Researchers calculated two indicators from body composition data to examine the relationship between muscle quality and long-term care need. People with low phase angles and extracellular to intracellular water resistance ratios were found to be at high risk of becoming dependent, especially when values fell below median thresholds.
Jennifer L. West, UVA Engineering Dean and Saunders Family Professor of Engineering, has been awarded the 2025 Pierre Galletti Award for her innovative research in biomaterials and nanomedicine. Her work has led to breakthroughs in treating cancer with precision, offering new hope to patients battling hard-to-treat cancers.