Articles tagged with Biomedical Engineering
Engineered cell lines are prone to misidentification, threatening scientific discoveries and intellectual property. Researchers at UT Dallas have developed a novel method to embed unique genetic identifiers, eliminating identification errors and safeguarding innovations with tamper-proof genomic tags.
Researchers create a device that prints bone grafts directly onto fractures and defects using a modified glue gun. The tool enables rapid creation of complex implants without pre-fabrication and demonstrates high structural flexibility, anti-inflammatory properties, and natural bone regrowth.
Researchers have developed an immunotherapy drug STF-1623 that safely prevents cancer cells from hiding from the immune system's first responders. The drug works by inhibiting ENPP1 proteins that destroy cGAMP, allowing it to trigger a broader immune response and suppress tumor growth.
Researchers Claudio Conci and Emanuele Riva at Politecnico di Milano have won two ERC Starting Grants to develop new brain stimulation technologies and diagnose inflammatory processes. The projects aim to revolutionize treatments for millions of people with tremors, neuropathic pain, and inflammation-related diseases.
The Korea University College of Medicine hosted the K-CLUB International Symposium to promote interdisciplinary collaboration and address global health challenges. Distinguished global scholars explored the future of human health from diverse perspectives, including clinical care, biomedical convergence, and health policy.
Researchers at Harvard SEAS have developed a gentler, more sustainable way to break down keratins and turn leftover wool and feathers into useful products. The process uses concentrated lithium bromide to create an environment favorable for spontaneous protein unfolding.
Researchers have created a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents. This innovative platform replicates the microenvironment of liver tumors, providing unprecedented insight into how tumors respond to embolization.
Researchers at SMART Alliance for Research and Technology developed a powerful tool to scan thousands of biological samples and detect transfer ribonucleic acid (tRNA) modifications, which help control cell growth and response to diseases. The tool opens up new possibilities for disease research, diagnostics, and treatment development.
Researchers at Seoul National University of Science and Technology developed a microelectrode with three-dimensional carbon nanotubes that efficiently conduct electricity while being soft like tissue. The arrays demonstrated stable insertion in brain tissues, precise recording of visual responses, and reduced inflammatory responses.
Researchers at Duke University developed a wireless patch that non-invasively measures skin and tissue stiffness, providing real-time feedback for medical applications like wound healing and chronic conditions. The technology also has potential for athletic performance optimization and rehabilitation.
Researchers identify heparanase 2 as a critical molecule in maintaining blood vessels' integrity. The study found that Hpa2 blocks growth-factor signaling, restoring balance without adverse side effects.
Researchers at UCLA have developed a wearable noninvasive brain-computer interface system that utilizes AI to interpret user intent, allowing participants to complete tasks significantly faster with assistance. The system demonstrates promising results for technology to assist individuals with limited physical capabilities.
Researchers developed novel sweat sensors that mimic the microtexture of rose petals, enhancing stability, performance, and comfort. The sensors demonstrate a self-cleaning effect, reducing skin irritation and improving user comfort, making them suitable for wearable devices like smartwatches.
The system uses magnetoelectric power-transfer technology to deliver precise electrical stimulation to organs like the heart and spinal cord. The more devices in the network, the more efficient it is, offering a less invasive alternative to traditional implantable medical devices. This technology has potential for treating conditions s...
Researchers are using total-body PET imaging to investigate the relationship between long COVID symptoms and activated immune T cells, as well as blood vessel damage. The goal is to gain a better understanding of how these processes are related and how they contribute to long COVID symptoms.
Researchers from Seoul National University of Science & Technology developed a smart adhesive system based on starfish for temporary and switchable underwater adhesion. The system exhibits high adhesion hysteresis, automatic release based on outside stimuli, and quick detachment by pneumatic actuation.
A new study finds that PAD2-mediated histone citrullination promotes tumor cell proliferation in pancreatic ductal adenocarcinoma. Knocking down the PAD2 gene reduces cell growth and increases survival rates. The researchers identify PAD inhibitors as potential therapeutic targets for treating PDAC.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
The American Thyroid Association has released new guidelines for managing adult patients with differentiated thyroid cancer, emphasizing evidence-based recommendations for diagnosis, treatment, and monitoring. The guidelines highlight the importance of patient-reported outcomes and areas for further research.
A researcher at MMRI is working on a project to monitor the health of vascularized composite allografts in wounded veterans. He aims to enable more widespread adoption of VCA transplantation by developing technologies to detect rejection early, allowing for modification of immunosuppressive therapies.
Catherine Whittington, a WPI researcher, has received a CAREER Award to develop laboratory models for the study of fibrosis in pancreas, skin, and uterine fibroids. The models will help researchers better understand factors at the cellular level that lead to fibrosis and how interventions can interrupt or reverse it.
A wearable robot has been upgraded to provide personalized assistance to ALS and stroke patients. The device uses machine learning and a physics-based model to adapt to an individual user's movements, offering more nuanced help with daily tasks.
Researchers developed a dynamic nomogram to predict long-term survival in patients with brain abscess, identifying key predictors such as age, Karnofsky performance status, and hemoculture results. The model offers an interactive tool for individualized risk assessment, facilitating better treatment decisions and improving outcomes.
Researchers at Columbia University School of Engineering and Applied Science developed a novel way to use light to control tissue folding in live embryos. By manipulating proteins that generate mechanical forces, they can now study 3D tissue biology outside developing embryos or build and control tiny machines made out of living biolog...
Researchers at Mizzou have identified two tiny molecules, agmatine and thiamine, that may serve as biomarkers for early detection of glaucoma. These metabolites could also be used to develop new neuroprotective treatments, aiming to slow or stop the progression of vision loss.
A team of researchers created a 3D-bioprinted model of stenotic brain blood vessels to study the effects of abnormal flow patterns on endothelial cells. The model successfully replicated physiological conditions, including upregulation of inflammatory markers.
Aging cells disrupt bone renewal and repair processes, leading to weak bones and joint degeneration. Cellular senescence and inflammation are major drivers of skeletal decline, while senolytics and emerging therapies offer promising new paths for treatment.
Researchers have developed a self-powered microneedle patch that can monitor biomarkers without drawing blood or relying on external devices. The patch uses dermal interstitial fluid (ISF) as a cleaner sample, which contains similar biomarkers to blood and doesn't require processing before testing.
A new platform combines bacteria and viruses to target cancer cells. The system hides a virus inside a tumor-seeking bacterium, smuggling it past the immune system and unleashing it inside cancerous tumors.
University of Houston researchers are developing an AI-powered dashboard for Florida food pantries, aiming to streamline stakeholder collaboration and distribute resources to families in need. The tool will enable emergency coordinators to respond quickly to spikes in demand, prioritizing the needs of vulnerable populations.
Researchers at the Institute of Molecular and Clinical Ophthalmology Basel discovered that differences in nerve signal speed and distance are actively balanced within the human eye to support a unified visual experience. This mechanism helps align signal arrival times to just a few milliseconds, contributing to synchronization.
A low-cost UAV imaging technique has been developed to accurately assess wheat plant height, revealing subtle variations and stable genetic loci. This method enhances the efficiency of marker-assisted selection in wheat breeding programs, offering a scalable tool for phenotyping plant height and improving crop yields.
Researchers developed an alginate-based microrobot that can be tracked using Magnetic Particle Imaging (MPI) and performs real-time localization, selective thermal therapy, and cell delivery. The robot is powered by a single magnetic actuation system independent of conventional medical imaging devices.
Researchers have developed a next-generation wireless ophthalmic diagnostic technology incorporating an ultrathin OLED into a contact lens. This breakthrough simplifies the conventional ophthalmic diagnostic environment, allowing patients to undergo retinal function tests while wearing the lens.
Researchers at Arizona State University have developed a rapid and accurate diagnostic test called NasRED that can detect diseases like COVID-19 with high sensitivity. The test uses tiny gold nanoparticles to identify disease-related proteins in a sample of bodily fluid, providing lab-quality accuracy without expensive equipment.
The new handbook provides a practical approach to harnessing zebrafish as a model organism for biomedical research, covering drug efficacy evaluation and disease mechanisms. It offers step-by-step experimental protocols and theoretical grounding for researchers of all levels.
Scientists at Yokohama National University have created a device that uses acoustic levitation and a squeeze film to move objects without friction, enabling fast and precise transport of small parts. The device was tested on an inclined surface and showed successful movement with weights up to 43 grams.
Researchers have developed an AI system that can recognize the early warning stages of laryngeal cancer from voice recordings. By analyzing variations in tone, pitch, and volume, the AI can distinguish between voices with benign vocal fold lesions and those with cancer. The study's findings offer a promising breakthrough for non-invasi...
Researchers have engineered CalBots, magnetic nanobots that can penetrate dentinal tubules and form durable seals, offering lasting relief from sensitivity. The study uses a new class of bioceramic cement to create a regenerative, active nanomaterial with potential implications for future healthcare.
A UCLA team has uncovered new details about the muscle controlling blinking, offering a pathway toward developing blink-assisting prostheses. The orbicularis oculi muscle contracts in complex patterns that vary by action and move the eyelid in more than just a simple up-and-down motion.
Researchers developed an organic molecule that simultaneously emits light suitable for displays and absorbs photons for deep-tissue bioimaging, overcoming a long-standing design challenge. The compound achieved high efficiency in both applications, paving the way for next-generation multifunctional materials.
Physicists from the IFJ PAN in Cracow have successfully produced homogeneous coatings of titanium oxide nanotubes on large metal surfaces, overcoming the obstacle of crystal grain boundaries. The method combines nanoparticle lithography and electrochemical anodization, enabling controlled material properties.
Silvia Blemker, a renowned biomedical engineer, has been elected to lead the American Society of Biomechanics. She aims to bolster industry ties, expand funding for students and early-career researchers, and promote interdisciplinary collaboration.
Researchers found that bystander CAR-negative CD8+ T cells expanded after CAR-T cell therapy and propagated with bispecific antibody treatment, leading to complete tumor remission. This study supports a new therapeutic effect of bystander T cells in combination with CAR-T and BsAb therapies.
Scientists have developed a breakthrough method to grow human kidney organoids from tissue stem cells, mirroring fetal kidney development over months. The organoids can be used for research and testing of new treatments for kidney diseases.
Scientists at UChicago Pritzker Molecular Engineering have developed polymer-based nanoparticles that self-assemble at room temperature in water, enabling stable delivery of proteins and RNA. These versatile particles can be used to carry various biologic drugs, including vaccines, with high efficiency and scalability.
Researchers have discovered a specialized mesenchymal-endothelial crosstalk that supports angiogenesis and osteogenesis, enabling periodontal bone regeneration. This communication network between mesenchymal stem cells and endothelial cells drives tissue repair and regeneration, holding promise for dental therapeutic strategies and bro...
A team of researchers is using NCSA resources to simulate the long-term progression of atrial fibrillation, a type of irregular heartbeat. By modeling the heart's electrical activity, they have uncovered a vicious cycle where adaptations to maintain calcium balance lead to continued arrhythmias and eventually a permanent condition.
Researchers discovered that magnetized surfaces significantly influence amyloid protein assembly, forming more fibrils and longer structures when aligned in one direction. The study suggests a new physical factor, Chiral-Induced Spin Selectivity (CISS), plays a direct role in protein self-assembly.
Researchers at Washington University in St. Louis have successfully induced a reversible torpor-like state in mice using focused ultrasound, offering a novel strategy for medical interventions. This technology aims to reduce energy demand and preserve organs for transplantation, promising to transform medicine.
A low-cost 'SimpleSilo' device mimics commercial silo bags without high cost, using inexpensive materials and easy-to-source supplies. The device demonstrated comparable performance to commercial silo bags and can be assembled by hospital staff in under an hour.
Researchers from the Institute of Physics of the Czech Academy of Sciences studied the biological effects of permanent magnetic fields and found that their distribution in space plays a critical role in healing. The study's detailed field maps offer practical guidance for optimizing magnet use in medicine and magnetobiology.
Researchers found that combining lavender essential oil with its own hydrosol effectively preserves skin-care emulsions against bacteria and fungi. The simple pairing kept counts below European Pharmacopoeia limits, even at high temperatures.
The journal is seeking high-quality submissions that explore the potential of voice and speech analysis in diverse medical applications. Submissions focus on acoustic and voice analysis techniques, voice or vocal phenotyping, and vocal biomarkers in health and medicine.
A new sleep algorithm developed by KAIST researchers helps users build healthy sleep habits by recommending the best bedtime based on their body's circadian rhythm. The algorithm is available on Samsung Galaxy smartwatches and aims to improve sleep quality and overall well-being.
Researchers at Chiba University have developed novel microfluidic devices that incorporate microcones to detect and characterize circulating tumor cells in blood. The devices demonstrated highly selective capture of human breast and lung cancer cells, with high efficiency even at high flow rates.
A new silicone patch with star-shaped microneedles, called the ExoPatch, distinguishes melanoma from healthy skin in mice, capturing cancer biomarkers from exosomes. The test shows promise for early detection of the most aggressive form of skin cancer without a biopsy or blood draw.
Researchers have demonstrated a novel vaccine delivery method using dental floss, which stimulates the production of antibodies in mucosal surfaces, such as the lining of the nose and lungs. This technique has shown superior antibody response compared to current oral vaccination methods.
Engineers at RMIT University have developed a new low-cost approach to creating 3D-printed titanium alloys, which are about a third cheaper than standard alloys. The new alloy has improved strength and performance compared to traditional 3D-printed titanium alloys.
Researchers designed a hydrogel system using milk-derived extracellular vesicles as both bioactive cargo and structural building blocks, enabling tissue engineering and regenerative medicine applications. The yogurt EVs promote healing and tissue regeneration without additional chemical additives.