Articles tagged with Biomedical Engineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A low-cost 'SimpleSilo' device mimics commercial silo bags without high cost, using inexpensive materials and easy-to-source supplies. The device demonstrated comparable performance to commercial silo bags and can be assembled by hospital staff in under an hour.
Researchers from the Institute of Physics of the Czech Academy of Sciences studied the biological effects of permanent magnetic fields and found that their distribution in space plays a critical role in healing. The study's detailed field maps offer practical guidance for optimizing magnet use in medicine and magnetobiology.
Researchers found that combining lavender essential oil with its own hydrosol effectively preserves skin-care emulsions against bacteria and fungi. The simple pairing kept counts below European Pharmacopoeia limits, even at high temperatures.
A new sleep algorithm developed by KAIST researchers helps users build healthy sleep habits by recommending the best bedtime based on their body's circadian rhythm. The algorithm is available on Samsung Galaxy smartwatches and aims to improve sleep quality and overall well-being.
Researchers at Chiba University have developed novel microfluidic devices that incorporate microcones to detect and characterize circulating tumor cells in blood. The devices demonstrated highly selective capture of human breast and lung cancer cells, with high efficiency even at high flow rates.
Researchers have demonstrated a novel vaccine delivery method using dental floss, which stimulates the production of antibodies in mucosal surfaces, such as the lining of the nose and lungs. This technique has shown superior antibody response compared to current oral vaccination methods.
Engineers at RMIT University have developed a new low-cost approach to creating 3D-printed titanium alloys, which are about a third cheaper than standard alloys. The new alloy has improved strength and performance compared to traditional 3D-printed titanium alloys.
A new silicone patch with star-shaped microneedles, called the ExoPatch, distinguishes melanoma from healthy skin in mice, capturing cancer biomarkers from exosomes. The test shows promise for early detection of the most aggressive form of skin cancer without a biopsy or blood draw.
Researchers designed a hydrogel system using milk-derived extracellular vesicles as both bioactive cargo and structural building blocks, enabling tissue engineering and regenerative medicine applications. The yogurt EVs promote healing and tissue regeneration without additional chemical additives.
Bonn researchers reduce cardiac arrhythmia after heart attacks by using gene therapy to overexpress connexin 43 in fibroblasts of cardiac scar tissue, leading to improved electrical connection between cells and reduced arrhythmias.
Researchers developed an AI platform to design proteins that arm immune cells to attack and kill cancer cells. The method reduces the process from years to just 4-6 weeks, offering a new approach to precision cancer treatment.
Researchers have developed a mechanical adhesive device that can attach to soft surfaces underwater, inspired by the hitchhiking sucker fish. The device uses pressure-based suction and has enhanced adhesion capabilities, making it suitable for delivering drugs in the GI tract or monitoring aquatic environments.
Researchers adapted optical coherence tomography (OCT) to visualize tiny structures in the human inner ear, correlating fluid levels with a patient's degree of hearing loss. The findings may help clinicians diagnose and treat hearing loss more quickly and effectively.
The article highlights the need for improved sepsis diagnosis, personalized treatment, and innovative trial designs. It advocates for a multifaceted approach integrating timely diagnosis, tailored therapy, and equitable implementation to tackle the global burden of sepsis.
Researchers developed a high-throughput phenotyping pipeline to analyze maize root development across genotypes, revealing extensive variability in root morphology and transcriptional profiles. Transcriptomic analysis identified thousands of differentially expressed genes related to hormone signaling, stress response, and cell wall org...
Researchers at MURR have optimized Terbium-161 for radiopharmaceutical use, enabling targeted destruction of cancer cells with high-energy electrons. The breakthrough could add extra therapeutic effectiveness to existing treatments without requiring new drug development.
A study published in Journal of the Mechanical Behavior of Biomedical Materials found that wrinkled skin is caused by its tendency to buckle under pressure due to age-related changes in its mechanical properties. As people age, their skin becomes more prone to wrinkles as it stretches and contracts in different directions.
Bioengineers at Harvard John A. Paulson School of Engineering and Applied Sciences have developed a computational model called BrainFlow that simulates cerebrospinal fluid flow in the presence of shunt implants, providing insight into optimal shunt design and placement for hydrocephalus patients.
The study explores the technological evolution of surgical robots and their current clinical applications. Surgical robots have addressed challenges in operating within small anatomical spaces, improving medical efficiency, but also increasing costs and complexity of operations.
A KAIST research team has identified a new molecular mechanism in which alcohol-damaged liver cells increase reactive oxygen species, leading to cell death and inflammatory responses. They discovered that Kupffer cells act as a 'dual-function regulator' that can either promote or suppress inflammation through interactions with liver ce...
A novel 3D culture method enables self-organization of precursor cell types into functional liver organoids capable of producing essential clotting factors. The breakthrough advances organoid-based therapies, drug testing, and disease modeling for liver diseases, including hemophilia A.
Recent advances in biofabrication and biomedical electronics have led to the development of biohybrid-engineered tissue (BHET) platforms, turning passive constructs into intelligent systems. These platforms show promise in diverse applications, including brain organoids and cardiac tissues, blurring the line between biology and machine.
Scientists have discovered that microglia play a crucial role in regulating blood flow to the brain, and targeting them may improve blood flow deficits. The study suggests that restoring microglia function could prevent or reverse memory-stealing diseases caused by lack of adequate blood flow.
Researchers aim to understand the role of blood vessels in traumatic brain injuries and their link to age-related cognitive impairment. They plan to use mice with a mutation in the UCH protein to explore how blocking this protein affects brain sugar processing and neurovascular function.
Researchers at Kyoto University have created a microphysiological system capable of simulating different regions of human lungs, including the airway and alveoli. This breakthrough enables accurate modeling of viral pathologies and holds promise for personalized treatment of respiratory diseases such as COVID-19.
A new deep learning model enhances handheld 3D medical imaging by automatically tracking transducer motion without external sensors. The model produces more realistic 3D US images and can reconstruct blood vessel structures using ultrasound and photoacoustic data.
Researchers at RCSI University of Medicine and Health Sciences have developed a 3-D printed implant that delivers electrical stimulation to injured areas of the spinal cord, enhancing nerve cell growth. The study has shown promising results in lab experiments and may enable new medical devices for traumatic spinal cord injuries.
Researchers at Texas A&M University have developed a new type of adhesive that could improve the comfort and safety of wearable medical devices. The adhesive, made from polyelectrolyte-complex coatings, is water-based and has been shown to match the strength of commercial-grade adhesives while reducing skin irritation.
Researchers have developed a 3D bio-printed model of lung tissue that closely mimics natural complexity, enabling better testing of respiratory diseases and drug development. The model can be adapted to include additional cell types or patient-derived cells, making it a powerful tool for personalized medicine and disease modeling.
Scientists at the Stowers Institute for Medical Research identified two distinct genes that regulate regeneration of sensory cells in zebrafish. The discovery may guide future studies on hearing loss and regenerative medicine in mammals, including humans.
Researchers developed a new imaging approach combining two-photon microscopy and advanced algorithms to improve resolution and reduce noise. This allowed them to clearly see details smaller than 250 nanometers, enabling real-time observations of mitochondrial behavior in live animals.
Researchers have engineered a monoclonal antibody that blocks allergic reactions against common pollen when applied inside the nose of mice, providing new hope for hay fever sufferers. The treatment, known as a 'molecular shield,' acts immediately and locally at the lining of the nose to prevent IgE antibodies from being activated.
The new agreement provides unlimited opportunities for open access publishing in JMIR's journals, eliminating article processing charges and streamlining the publication process. This partnership underscores TU/e's commitment to advancing open science and increasing research impact.
Researchers at MIT developed an implantable device that can store glucagon to counteract hypoglycemia, a life-threatening condition for people with Type 1 diabetes. The device, about the size of a quarter, contains a small reservoir made of 3D-printed polymer and can be triggered remotely or automatically by a sensor.
Researchers have identified a hidden molecular mechanism involving two proteins that allows tumors to resist treatment. A new gelatin-based nanoparticle has been developed to shut down both proteins simultaneously, showing promising results in early studies with mice.
Researchers found that human stem cells can differentiate into bone cells simply by being squeezed through narrow spaces. This discovery could lead to the development of simpler and safer regenerative therapies by using physical signals instead of chemical cues. The study's findings have broader implications, including potential applic...
A new technology combines the coffee-ring effect with plasmonics and AI for rapid diagnostics, offering highly accurate results in under 12 minutes. The test can spot diseases like COVID-19, prostate cancer, and sepsis, making it a game-changer for point-of-care diagnostics.
GeniPhys has received FDA clearance for its self-assembling collagen scaffold, Collymer Self-Assembling Scaffold (SAS), which supports cellular infiltration and vascularization. The technology is indicated for various wound types and anchors a growing intellectual property portfolio with nearly 20 issued or pending patents.
A new computational method combines 4D flow MRI, CFD, and data assimilation to estimate blood flow in brain aneurysms with greater accuracy and efficiency. The approach focuses on the aneurysm region, reducing computational cost while improving flow estimation.
Chihtong Lee's research on retractor blade geometry explores how small design changes can improve patient recovery after spinal surgery. Her work, conducted in collaboration with Baylor College of Medicine, showed that blades with soft, biocompatible coatings significantly reduced tissue stress and postoperative complications.
Researchers from UCLA have developed innovative biomaterial strategies to mimic immunological synapses, enhancing T cell activation rates and long-term efficacy in CAR-T therapy. The approaches leverage flexible interfaces and mechanical properties to promote memory T cell formation and distribution.
A novel fluorescent probe, SLY, has been developed to precisely identify hepatocellular carcinoma tissue using sialylated glycans on the cell surface. The probe outperforms conventional methods by clearly distinguishing tumor margins within liver tissues.
Researchers have developed a fabric-based electrochemical biosensing system that enables autonomous sweat collection and molecular analysis across varied scenarios. The system uses a skin-interfaced stabilized hydrogel electrode to deliver a mild current that activates sweat glands, allowing for real-time health monitoring without rely...
The study proposes a modified ResUNet approach for automated liver segmentation from CT images, achieving high precision and accuracy. The model outperforms traditional methods, demonstrating stable performance in cross-dataset tests.
Researchers at the University of Surrey have identified genes that disrupt the survival of 'zombie' TB cells, which are resistant to antibiotics. By understanding these mechanisms, scientists can develop new drugs that target persisters and shorten treatment regimens.
A new study by University of Missouri researchers found that states granting full practice authority to APRNs significantly improves health outcomes and increases access to care. In contrast, restricted practice laws impose financial burdens on patients and limit APRN autonomy.
Researchers have developed a technique to grow stem cells into single sheets, increasing the secretion of signaling proteins that help repair tissue and regulate the immune system. This new approach could improve stem cell-based treatments for conditions such as heart disease, liver damage, and autoimmune illnesses.
Researchers developed an in-silico meta-analysis tool to determine optimal laser irradiation conditions for treating nevus of Ota. The study found that picosecond laser treatment demonstrated higher efficacy and equivalent safety compared to nanosecond laser treatment.
Researchers at the Wyss Institute have identified vorinostat as a promising treatment for Rett Syndrome using an AI-driven drug discovery process and innovative disease modeling. The findings demonstrate disease-modifying abilities across multiple tissues, offering hope for a potentially curative treatment.
Scientists have developed a miniature device that mimics human bone marrow and immune environment, enabling predictive testing of cancer immunotherapy success in patients. The device recreates three regions of bone marrow where leukemia develops and retains the complex immune environment of the tissue.
Researchers have successfully controlled a dexterous robotic hand using noninvasive EEG-based Brain-Computer Interfaces (BCIs) for individual finger movements. The study demonstrates real-time brain decoding and motor imagery control, paving the way for potential applications beyond basic communication to intricate motor control.
Researchers developed patient-specific Cancer Chips to model esophageal tumor microenvironments, enabling accurate prediction of chemotherapy responses. The approach can rapidly stratify patients into responders and non-responders, paving the way for personalized medicine.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
The new centre will investigate neural dynamics, developing novel interventions and devices to improve symptom relief and quality of life for people with brain disorders. It aims to harness neural dynamics for people with conditions like Parkinson’s disease or epilepsy.
Researchers found increased activity in two brain areas when participants reported cognitive fatigue: the right insula and dorsal lateral prefrontal cortex. These areas work together to regulate mental effort, suggesting that external incentives can prompt increased cognitive effort.
UVA Health received two anonymous $25 million estate gifts to support the Paul and Diane Manning Institute of Biotechnology. The institute will develop new treatments for hard-to-treat diseases with a state-of-the-art biomedical research facility expected to drive economic growth in Central Virginia.
Researchers from Binghamton University confirm the long-held 'urban myth' that saltwater dries out skin, increasing tissue stiffness and stress. A simple solution to alleviate tightness is taking a shower after coming out of the ocean.
Scientists from Institute of Science Tokyo create photo-switchable binding of DNA nanostructures that generate two distinct directional motions. The research paves the way for innovative fluid-based diagnostic chips and molecular computers.
Researchers at UC Irvine have successfully tested a new replacement heart valve designed for toddlers and young children with congenital cardiac defects. The Iris Valve can be implanted via a minimally invasive catheter, allowing treatment to begin earlier in very young patients.
Scientists have created a novel method to distinguish between healthy and senescent cells using electric fields, marking a fresh start in ageing research. The frequency-modulated dielectrophoresis (FM-DEP) technique is label-free, rapid, and easy to apply, allowing for the characterization of cell type by measuring the cutoff frequency.