Articles tagged with Biomedical Engineering
The Emory BioFoundry Institute is investing in TopoDx, a MedTech startup developing rapid antimicrobial susceptibility testing. This technology addresses the growing threat of antibiotic resistance and aims to improve patient outcomes. With EBFI's support, TopoDx plans to accelerate towards FDA clearance and commercial deployment.
A new study finds that over 50% of small-molecule drug patents this century are connected to NIH-backed research that would likely be cut under a 40% budget reduction. This highlights the significant impact of federally funded research on the development of life-changing medicines.
Professor Lim Chwee Teck, Director of NUS iHealthtech, has been elected an International Fellow of the Royal Academy of Engineering for his pioneering research in biomedical engineering and wearable technologies. His work on disease diagnosis and therapy has translated into impactful healthcare solutions through start-ups.
Duke University researchers discovered that inhibiting an enzyme involved in iron regulation makes cancer cells vulnerable to cell death. By targeting STK17B kinase, they reactivated ferroptosis and increased the effectiveness of conventional therapies against multiple myeloma.
A new 3D imaging technique combines intensity diffraction tomography with adaptive optics to track subcellular structures over extended periods. This approach achieves high spatiotemporal resolution and molecular specificity, enabling the study of cellular dynamics.
Researchers at CU Boulder have developed a new method for creating human rabies vaccines that are stable at high temperatures and can be stored in a dry powder form. This innovation addresses the storage challenges faced by developing countries, where traditional vaccines often require refrigeration or specialized cold storage equipment.
Researchers at RMIT University have created a 3D-printed diamond–titanium device that can harvest energy from flowing liquid and receive wireless power, paving the way for smarter, safer implants. The innovation combines semiconductive diamonds with metallic titanium to create a structure that is both lightweight and electrically active.
Researchers have created a new class of lipid nanoparticles (LNPs) with complex internal arrangements, expanding their potential for carrying small-molecule drugs, proteins, metal ions, and mRNA. The breakthrough offers flexibility in designing delivery systems for different therapeutic molecules.
A research team developed a pipeline using pre-trained large language models to unify radiology and pathology reports, achieving high accuracy in tumor presence and stability. The system also predicted survival outcomes without additional training, distinguishing high-risk from low-risk groups.
Developed by a multidisciplinary team at Politecnico di Milano, the BAMBI device is an effective engineering solution to stop postnatal haemorrhages. The kit includes a rectal probe and saline solution with a patented connector for safe assembly.
Scientists at Nano Life Science Institute create a thermogenetic tool using elastin-like polypeptides to regulate protein activation temperature. This technology enables controlled apoptosis in human-derived cells and has potential applications for biotechnological tools.
Researchers at Graz University of Technology created a highly detailed digital twin of the A549 lung cancer cell line, paving the way for individualized cancer treatment. The model simulates calcium dynamics and electrical voltages, allowing for testing of drugs and personalized treatment strategies.
Researchers at Rice University have developed a soft but strong metamaterial that can be controlled remotely to rapidly transform its size and shape. The new material is designed for implantable and ingestible medical devices and addresses critical safety concerns such as gastric ulcers and puncture injuries.
Mass General Brigham has identified key areas of innovation in medicine, including gene editing, immune system modulation, AI-powered care, and organ transplantation. The 'Big Ideas in Medicine' aim to transform diagnosis, treatment, and prevention of disease with next-generation technologies.
Researchers at Queensland University of Technology have created a prototype electronic device using chitosan, a naturally derived biopolymer from seafood waste. The material is used to create flexible and wearable health sensors that can monitor vital signs without compromising comfort or the environment.
Researchers review nuclear receptor role in brain cancer development and explore their potential as therapeutic targets. Modulating these receptors with selective agonists or antagonists may offer new avenues for therapy, such as blocking androgen and estrogen receptors.
Researchers developed DF-FPDT to address low-frequency loss from non-matched illumination in live-cell imaging, enabling high-resolution and high-contrast 3D reconstructions. This breakthrough technique leverages non-matched illumination to enhance structural details without additional hardware or post-processing.
Scientists have achieved a major breakthrough by 3D bioprinting miniature placentas, which can accurately replicate the human placenta. This technology has the potential to transform pregnancy research by allowing for the study of serious complications like preeclampsia.
Researchers from UC3M and the Spanish Space Agency conducted a parabolic flight campaign to study microgravity's effects on human body, testing an innovative technique to protect cardiovascular and ocular health. The results will be crucial for future space exploration and could have applications on Earth for treating vascular diseases.
A collaborative team from Texas Tech University Health Sciences Center has received a five-year, $2.9 million R01 grant and a competitive renewal of $3 million to explore therapies for ischemic stroke. The team aims to develop medications that mimic the brain's self-protective mechanisms.
Researchers at NUS have developed a bioengineering approach to keep human lymph node tissue alive and functioning outside the body for several days. The method involves embedding thin slices of lymph node tissue in a soft gel that mimics the body's natural environment, allowing for detailed studies of immune cell behavior.
A team of researchers has received funding to study the PRPH2 gene, crucial for normal vision, but when mutated causes a range of retinal diseases leading to blindness. They aim to uncover the underlying mechanisms of PRPH2-associated pathology to develop effective therapies.
Researchers developed wearable microneedle patches that improve drug absorption while reducing pain in long-term delivery. The new technology, inspired by bee stings, enables continuous drug release and anchors securely into the skin.
The summit explores the future of digital health, covering AI and health data, biotechnology and digital health, and collaboration and commercialization. Key findings include the importance of interdisciplinary collaboration and innovative thinking in healthcare development.
Graz researchers investigate homocysteine's impact on the aorta, finding elevated levels lead to stiffer and less elastic vessels. This discovery contributes to understanding of cardiovascular diseases like atherosclerosis.
Researchers use biomolecular condensates to control gene expression, mimicking the cell nucleus's efficient information processing. They aim to develop DNA-based computer systems and biotechnologies like cancer therapies.
A new USF study discovers that chameleons and salamanders use the same biological mechanism to fire their tongues at extreme speeds, with potential applications in biomedical devices and space retrieval tools. The researchers hope to expand their studies to examine how animal tongues retract with such speed and precision.
A new hydrogel has been developed to combat vaginal changes caused by menopause, offering a hormone-free alternative for treatment. The study found that the hydrogel improved vaginal tissue thickness and reduced inflammation, providing potential relief from symptoms such as dryness and pain.
Researchers developed photo-inducible binary interaction tools (PhoBITs) to precisely control gene expression, cell signaling, and immune responses. PhoBITs enable targeted treatment with minimal side effects, opening new avenues for cancer therapy, immunotherapy, and regenerative medicine.
Scientists developed hollow microspheres with adjustable pore size, adhesion, and lubricity properties using mucus and polydopamine. These spheres can be used as drug delivery agents and may prevent tissue damage or provide a protective coating.
Researchers develop coral-inspired capsule that captures bacteria from small intestine, providing a more comprehensive picture of the gut's bacterial landscape. The device promises to revolutionize microbiome science and enable early disease detection and targeted therapeutic interventions.
Engineered cell lines are prone to misidentification, threatening scientific discoveries and intellectual property. Researchers at UT Dallas have developed a novel method to embed unique genetic identifiers, eliminating identification errors and safeguarding innovations with tamper-proof genomic tags.
Researchers create a device that prints bone grafts directly onto fractures and defects using a modified glue gun. The tool enables rapid creation of complex implants without pre-fabrication and demonstrates high structural flexibility, anti-inflammatory properties, and natural bone regrowth.
Researchers have developed an immunotherapy drug STF-1623 that safely prevents cancer cells from hiding from the immune system's first responders. The drug works by inhibiting ENPP1 proteins that destroy cGAMP, allowing it to trigger a broader immune response and suppress tumor growth.
Researchers at UMC Utrecht developed a new AI-powered printer called GRACE that can print implantable tissues with improved cell survival and functionality. The printer uses computer vision and laser-based imaging to design and print complex structures, including blood vessels and cartilage layers.
The Korea University College of Medicine hosted the K-CLUB International Symposium to promote interdisciplinary collaboration and address global health challenges. Distinguished global scholars explored the future of human health from diverse perspectives, including clinical care, biomedical convergence, and health policy.
Researchers at Harvard SEAS have developed a gentler, more sustainable way to break down keratins and turn leftover wool and feathers into useful products. The process uses concentrated lithium bromide to create an environment favorable for spontaneous protein unfolding.
Researchers Claudio Conci and Emanuele Riva at Politecnico di Milano have won two ERC Starting Grants to develop new brain stimulation technologies and diagnose inflammatory processes. The projects aim to revolutionize treatments for millions of people with tremors, neuropathic pain, and inflammation-related diseases.
Researchers at SMART Alliance for Research and Technology developed a powerful tool to scan thousands of biological samples and detect transfer ribonucleic acid (tRNA) modifications, which help control cell growth and response to diseases. The tool opens up new possibilities for disease research, diagnostics, and treatment development.
Researchers at Seoul National University of Science and Technology developed a microelectrode with three-dimensional carbon nanotubes that efficiently conduct electricity while being soft like tissue. The arrays demonstrated stable insertion in brain tissues, precise recording of visual responses, and reduced inflammatory responses.
Researchers have created a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents. This innovative platform replicates the microenvironment of liver tumors, providing unprecedented insight into how tumors respond to embolization.
Researchers identify heparanase 2 as a critical molecule in maintaining blood vessels' integrity. The study found that Hpa2 blocks growth-factor signaling, restoring balance without adverse side effects.
Researchers at Duke University developed a wireless patch that non-invasively measures skin and tissue stiffness, providing real-time feedback for medical applications like wound healing and chronic conditions. The technology also has potential for athletic performance optimization and rehabilitation.
Researchers at UCLA have developed a wearable noninvasive brain-computer interface system that utilizes AI to interpret user intent, allowing participants to complete tasks significantly faster with assistance. The system demonstrates promising results for technology to assist individuals with limited physical capabilities.
Researchers developed novel sweat sensors that mimic the microtexture of rose petals, enhancing stability, performance, and comfort. The sensors demonstrate a self-cleaning effect, reducing skin irritation and improving user comfort, making them suitable for wearable devices like smartwatches.
The system uses magnetoelectric power-transfer technology to deliver precise electrical stimulation to organs like the heart and spinal cord. The more devices in the network, the more efficient it is, offering a less invasive alternative to traditional implantable medical devices. This technology has potential for treating conditions s...
Researchers are using total-body PET imaging to investigate the relationship between long COVID symptoms and activated immune T cells, as well as blood vessel damage. The goal is to gain a better understanding of how these processes are related and how they contribute to long COVID symptoms.
A new study finds that PAD2-mediated histone citrullination promotes tumor cell proliferation in pancreatic ductal adenocarcinoma. Knocking down the PAD2 gene reduces cell growth and increases survival rates. The researchers identify PAD inhibitors as potential therapeutic targets for treating PDAC.
Researchers at Lehigh University and the Cleveland Clinic are developing a nonsurgical therapy for pelvic organ prolapse using drug-delivering nanoparticles. The treatment aims to delay or reverse matrix degradation, reducing the severity of POP in patients with earlier stages of the disorder.
Researchers from Seoul National University of Science & Technology developed a smart adhesive system based on starfish for temporary and switchable underwater adhesion. The system exhibits high adhesion hysteresis, automatic release based on outside stimuli, and quick detachment by pneumatic actuation.
The American Thyroid Association has released new guidelines for managing adult patients with differentiated thyroid cancer, emphasizing evidence-based recommendations for diagnosis, treatment, and monitoring. The guidelines highlight the importance of patient-reported outcomes and areas for further research.
A researcher at MMRI is working on a project to monitor the health of vascularized composite allografts in wounded veterans. He aims to enable more widespread adoption of VCA transplantation by developing technologies to detect rejection early, allowing for modification of immunosuppressive therapies.
Catherine Whittington, a WPI researcher, has received a CAREER Award to develop laboratory models for the study of fibrosis in pancreas, skin, and uterine fibroids. The models will help researchers better understand factors at the cellular level that lead to fibrosis and how interventions can interrupt or reverse it.
A wearable robot has been upgraded to provide personalized assistance to ALS and stroke patients. The device uses machine learning and a physics-based model to adapt to an individual user's movements, offering more nuanced help with daily tasks.
Researchers developed a dynamic nomogram to predict long-term survival in patients with brain abscess, identifying key predictors such as age, Karnofsky performance status, and hemoculture results. The model offers an interactive tool for individualized risk assessment, facilitating better treatment decisions and improving outcomes.
Researchers at Columbia University School of Engineering and Applied Science developed a novel way to use light to control tissue folding in live embryos. By manipulating proteins that generate mechanical forces, they can now study 3D tissue biology outside developing embryos or build and control tiny machines made out of living biolog...
Researchers at Mizzou have identified two tiny molecules, agmatine and thiamine, that may serve as biomarkers for early detection of glaucoma. These metabolites could also be used to develop new neuroprotective treatments, aiming to slow or stop the progression of vision loss.
A team of researchers created a 3D-bioprinted model of stenotic brain blood vessels to study the effects of abnormal flow patterns on endothelial cells. The model successfully replicated physiological conditions, including upregulation of inflammatory markers.
Aging cells disrupt bone renewal and repair processes, leading to weak bones and joint degeneration. Cellular senescence and inflammation are major drivers of skeletal decline, while senolytics and emerging therapies offer promising new paths for treatment.
Researchers have developed a self-powered microneedle patch that can monitor biomarkers without drawing blood or relying on external devices. The patch uses dermal interstitial fluid (ISF) as a cleaner sample, which contains similar biomarkers to blood and doesn't require processing before testing.