Articles tagged with Biomedical Engineering
The collaboration aims to improve human tolerance to xenogeneic organs and reduce the risk of organ rejection. Researchers will explore immunomodulatory interventions to support patients with high unmet needs who face additional barriers to receiving timely liver transplants.
ASTRA-Net helps reconstruct overlooked peripheral airways, creating more complete maps for bronchoscopy procedures. The AI framework demonstrates strong performance in identifying fine peripheral airways and supports navigation to difficult-to-reach lung lesions.
Light-field microscopy (LFM) enables snapshot volumetric acquisition, allowing for faster synchronous three-dimensional information. Recent advances have made LFM practical for high-speed neuroimaging, particularly in calcium imaging and voltage imaging.
Researchers developed a new drug called CS18 that targets TopBP1, a biological switchboard controlling multiple cancer-driving pathways. CS18 reduces defenses helping cancer cells survive therapy and increases genes stopping uncontrolled growth.
A new wearable electric-field device has been shown to slow the growth and spread of aggressive breast cancer in preclinical models. The technology uses low-intensity electric fields that interact with cancer cells in a controlled way, reducing tumor growth and increasing immune responses.
A new portable blood testing device connects via Bluetooth and uses AI to analyze blood samples, providing real-time health insights. This technology allows for regular monitoring of patients undergoing chemotherapy or taking medications with potential side effects.
Researchers developed realistic skin-like test models to reproduce a range of skin tones and simulate blood flow, helping device developers identify biases in light-based medical technologies. The models showed improved optical signals detection across different pigmentation levels.
A new study found that children preparing for stem cell transplantation already have subtle respiratory abnormalities, including increased small-airway resistance and greater lung stiffness. These abnormalities are likely related to their underlying disease or previous therapies rather than the transplant itself.
A team at Pusan National University created a stretchable organic electrochemical transistor that can be easily reprogrammed to perform different functions. The device combines logic, memory, and a visible color readout without complex circuitry.
Researchers developed an AI model capable of generating accurate, high-resolution pressure maps using just a few anatomical landmarks, enabling lower-cost foot health monitoring in rural and remote regions. The study demonstrates the potential for AI to overcome challenges associated with traditional plantar pressure monitoring systems.
Researchers explore how engineered lanthanide carriers can tune the optical and magnetic properties of ions for improved signal contrast and reduced background signals in biomedical imaging. The study highlights opportunities for multimodal imaging, theranostics, and AI-guided probe design.
Researchers at Institute of Science Tokyo developed strategies to overcome xenophagocytosis, which eliminates living donor cells in interspecies organ generation. By blocking this response, they significantly improved donor cell survival and generated rat pancreas in mice.
Researchers propose a four-stage pathway to evaluate AI for intracranial aneurysm detection, including lesion-level testing, reader performance evaluation, and surveillance after deployment. The framework aims to assess the tool's net clinical benefit in specific care settings.
Recent progress in lanthanide carriers is mapped to improve biomedical imaging and diagnosis, combining optical, X-ray, and magnetic resonance imaging techniques. These carriers enable high-resolution imaging with tunability for different applications, reducing tissue damage and enhancing image clarity.
Researchers at the University of Manchester have developed a new family of antifungal agents that are more potent and less toxic than existing treatments. The compounds, which were discovered through genome mining, showed increased antifungal activity and improved solubility compared to existing drugs.
Researchers at the University of Queensland have developed ultra-wideband radar sensors to measure muscle forces in a non-invasive way. This technology has the potential to improve rehabilitation, injury prevention, and recovery for people with motor neuron disease or aging. The goal is to eventually use real-time sensor data to assist...
Researchers have developed a way to quickly create customizable synthetic blood vessel grafts in just minutes using additive manufacturing. The new technique, called Focused Rotary Jet Spinning, allows for precise control over diameter and wall thickness, making it ideal for acute trauma situations and complex pediatric heart surgeries.
Scientists at the University of Osaka have created a new technique to build blood supply systems for artificial tissues. They successfully fabricated tubular hydrogel structures with controlled lumen sizes and complex geometries, paving the way for creating vascular models that can investigate the development of fully synthetic tissues.
Dr. Yi Li receives CPRIT funding to develop treatments for solitary fibrous tumor, a rare cancer driven by gene fusions. Researchers are working on novel therapies, including immunotherapy and antisense oligonucleotides, to reduce cancer-causing signal activity.
A new study from Reichman University found that a short three-week digital training program improved motor function and brain activity in Parkinson's patients. The program, called DopApp, strengthened connectivity between brain regions responsible for movement and induced localized changes in neural circuits.
Emerging non-endocytic delivery strategies enable direct cytosolic delivery of proteins, nucleic acids, and gene-editing tools, providing new opportunities for biomedical therapies. The review discusses their application prospects in gene therapy, macromolecular drug delivery, and cellular engineering.
A Chinese research team has proposed a novel approach to separate dimethyl carbonate from methanol using a tailor-made ionic liquid and heat pump-assisted distillation. The method significantly reduces energy consumption and costs compared to traditional methods, making it an attractive solution for the chemical industry.
Researchers at HKUST develop a biocompatible chemical reaction to create targeted anticancer prodrugs, enabling precise drug activation in cancer cells. The breakthrough uses the EBB group and gold catalysts, offering a promising strategy for reducing collateral toxicity.
Researchers at Binghamton University are developing an ear probe that utilizes the unique way spiders 'hear' through their webs to detect inner-ear problems. The probe uses patented sensing technology inspired by spider silk, which can respond to sound with perfect fidelity from 1 Hz up to 50 kHz.
The US Naval Research Lab is developing continuous biomanufacturing technologies to produce critical materials more efficiently and sustainably. The approach uses surface-bound microbial cells to generate valuable compounds over extended periods, reducing energy requirements and equipment size.
Researchers have developed a novel method to control miniature rotations using water flow at a surface, allowing for the creation of targeted ultrafine structures such as twisted fibers for wires and sutures. This approach enables the assembly of complex structures without mechanical contact or chemical propulsion systems.
JMIR Publications is sponsoring the upcoming BioMedEng26 conference to promote biomedical engineering innovation. The journal JMIR Biomedical Engineering will be highlighted during the event, with Dr. Javad Sarvestan discussing its focus on cutting-edge engineering applications and peer-review process.
Scientists at UVA have developed a new method to target glioblastoma, the most common and deadly brain cancer, by delivering microRNAs through the brain's natural barrier. The approach shows promise in slowing tumor growth and extending survival in animal models.
Researchers at Science Tokyo develop a Ramsey-based magnetometer that overcomes thermal limitations, enabling close-proximity detection of weak biomagnetic signals. The sensor achieves high sensitivity and safe operation near biological tissue.
A UMass Amherst-led team is developing a new approach to prevent bladder cancer recurrence by exfoliating the bladder lining. The technology uses irreversible electroporation to target premalignant cells, offering a potential alternative to surgical removal or aggressive treatments.
A new model, PSIDMViT, combines anatomy, physics, and machine learning to predict accurate dose distributions for CyberKnife radiation therapy. The study shows improved agreement with Monte Carlo reference doses and reduced computation time, suggesting a promising strategy for improving radiotherapy dose prediction.
Researchers identified simple changes to surgical tools that can significantly affect how pressure is distributed across the esophageal wall during neck surgery. Wider retractor blades reduced stress beneath the center of the blade by up to 82%, but also shifted higher stress toward the edges.
Researchers have identified a widespread source of error in a popular genome study method and created a machine-learning tool to correct it. PATTY uses machine learning to reduce artifacts while preserving real signals in noisy data, giving researchers a clearer view of gene activity control.
The study reveals that different forms and levels of partner proteins involved in the disease lead to distinct molecular interactions and biological outcomes in different tissues. The findings suggest that directing therapies to specific protein forms may improve treatment options for neurological diseases.
A research team developed a walking-support robot that uses large-area tactile contact at the torso to track movement intent and share load. The system continuously adapts as the coupled human-robot dynamics evolve, allowing intention alignment and balance support to emerge from the same physical channel.
A new study published in Chinese Neurosurgical Journal found that real-time MRI and brain function monitoring during neurosurgery can improve the removal of tumors affecting the corpus callosum more effectively and safely. This multimodal approach gave patients about 30 extra months after treatment before the tumor grew back or worsene...
A novel biological pathway has been uncovered that can lead to seizures when disrupted, providing a new approach for improved diagnosis. The study identifies an association between defective genes and increased glutamatergic transmission, which can increase the risk of seizures.
University of Oregon researchers engineer molecules and control regenerative cue release to improve healing outcomes for complex injuries. A staggered sequence approach shows better blood vessel regeneration, and the method is being applied to bone healing, muscle repair, and spinal cord regeneration.
Researchers found subtle patterns in brain activity while children listened to speech linked to verbal communication abilities in autistic youths. Altered brain signals suggested the brain may process speech less efficiently, with noisier signals associated with lower scores on everyday verbal communication.
Researchers at Baylor College of Medicine identified a vulnerability in triple-negative breast cancers with LIG1 loss and used it to develop a new therapy for chemotherapy-resistant TNBC tumors. A combination of olaparib and ceralasertib showed significant effectiveness in reducing tumor growth in animal models.
A study by Pompeu Fabra University, ONT, and Vall d'Hebron Hospital reveals that public investment in liver transplants not only improves patient survival but also generates a positive social and economic return. The study estimates that liver transplant patients contribute over 100 million euros to the Spanish economy annually.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
Researchers at MIT have created a precise way to engineer artificial blood vessels by mechanically stretching and pulling a "blood vessel on a chip". The new method, reported in the Proceedings of the National Academy of Sciences, enables controlled sprouting of new vessels and programming of their growth patterns.
A new award will help advance the proof-of-concept work toward commercialization of an at-home HIV test that detects cases not caught by lab tests. The device, called Click Chemistry Amplified Nanopore (CAN) sensing, has shown promising results in early studies.
Researchers developed DeepHHF, an AI model that identifies patients at high risk of heart failure up to five years in advance. The model analyzes standard ECG recordings and detects subtle abnormalities that are often imperceptible to the human eye.
Flexible electromagnetic induction-type tactile sensors offer a promising route for low-power, robust and self-powered interfaces. The researchers provided a systematic roadmap for development, including application-oriented design and multimodal integration with other sensing mechanisms.
Researchers at Terasaki Institute develop a wireless dual-compartment biochemical monitoring platform for real-time tracking of key biomarkers in perfusion fluid and bile during normothermic machine perfusion. The study shows improved interpretation of post-transplant outcomes with combined bile and perfusate data.
Researchers developed nanoparticles that retain their protective coating in normal tissue but shed it upon reaching tumor tissue, releasing anticancer drugs. This technology reduces systemic side effects and enhances treatment efficacy.
Experts recommend implementing safer technologies and modernizing radiation safety standards to reduce preventable radiation exposure and orthopedic injuries. The consensus statement emphasizes the need for mandatory action to prioritize protecting healthcare workers, ensuring a healthy workforce for patients' access to lifesaving care.
Researchers at Penn State have developed paint-on tattoos that can power sensors and track health data like heart rate and brain waves. The innovative conductive ink can be customized with various colors and designs, providing a comfortable and accurate wearable solution.
A novel gene promoter called cmGAD67 shows promise for treating drug-resistant epilepsy by selectively stimulating inhibitory neurons. The study found that the promoter drove strong and highly selective gene expression in specific brain regions, reducing abnormal electrical activity and seizures.
Baylor researchers developed a novel method of somatic gene editing in mice to generate tumor models. The new rat models closely mimic human disease biology, response to therapy and immune microenvironment, offering a powerful way to study cancers not well studied in mouse models.
Researchers at McMaster University have developed a targeted approach to treating IBD using bacteriophages, which selectively target harmful bacteria without disrupting the gut ecosystem. The phage therapy significantly reduced gut inflammation and enhanced the effectiveness of steroid treatments.
Researchers at Texas A&M University have developed a technique that maps chemical changes directly, using natural molecular vibrations. This allows for the observation of biological processes in real-time, giving researchers a more complete picture of how diseases emerge and evolve.
Researchers at the University of Pittsburgh developed a new imaging technique to visualize nerve patterns in densely innervated joints, such as the temporomandibular joint (TMJ). The c-Clear method produces a three-dimensional map of nerves with minimal tissue damage, allowing for better understanding of disorders like TMDs and TMJ pain.
The University of Hong Kong's HKUMed team successfully introduced robot-assisted microsurgery, performing 48 procedures with no complications. The technology enhances precision and control, making it possible for more surgeons to perform intricate microvascular surgeries.
A new study found that clinician support significantly increases patient adoption of virtual reality therapies, leading to better time-based adherence and technology acceptance. The research team evaluated three implementation environments, with provider-led support demonstrating the most favorable usability pattern.
Researchers have developed a microfluidic platform that recreates the complex ecosystem surrounding pancreatic tumors and observed how cells interact dynamically. The findings reveal a critical mechanism that may explain why many therapies fail and point to new therapeutic strategies.
Researchers will study blood samples and environmental exposures over 10 years to identify genetic, environmental, and cellular factors contributing to autoimmune diseases. The goal is to develop prevention strategies and treatments by understanding the earliest biological triggers of SARDs.
A new imaging technology at UH helps scientists study exosomes, tiny particles released by human cells that may be targets for diseases. The technology uses advanced lighting at the nanoscale to analyze exosomes one at a time, measuring features to pinpoint good drug targets.