Articles tagged with Biomedical Engineering
Researchers developed DeepHHF, an AI model that identifies patients at high risk of heart failure up to five years in advance. The model analyzes standard ECG recordings and detects subtle abnormalities that are often imperceptible to the human eye.
Experts recommend implementing safer technologies and modernizing radiation safety standards to reduce preventable radiation exposure and orthopedic injuries. The consensus statement emphasizes the need for mandatory action to prioritize protecting healthcare workers, ensuring a healthy workforce for patients' access to lifesaving care.
Flexible electromagnetic induction-type tactile sensors offer a promising route for low-power, robust and self-powered interfaces. The researchers provided a systematic roadmap for development, including application-oriented design and multimodal integration with other sensing mechanisms.
Researchers at Terasaki Institute develop a wireless dual-compartment biochemical monitoring platform for real-time tracking of key biomarkers in perfusion fluid and bile during normothermic machine perfusion. The study shows improved interpretation of post-transplant outcomes with combined bile and perfusate data.
Researchers developed nanoparticles that retain their protective coating in normal tissue but shed it upon reaching tumor tissue, releasing anticancer drugs. This technology reduces systemic side effects and enhances treatment efficacy.
Researchers at Penn State have developed paint-on tattoos that can power sensors and track health data like heart rate and brain waves. The innovative conductive ink can be customized with various colors and designs, providing a comfortable and accurate wearable solution.
Baylor researchers developed a novel method of somatic gene editing in mice to generate tumor models. The new rat models closely mimic human disease biology, response to therapy and immune microenvironment, offering a powerful way to study cancers not well studied in mouse models.
A novel gene promoter called cmGAD67 shows promise for treating drug-resistant epilepsy by selectively stimulating inhibitory neurons. The study found that the promoter drove strong and highly selective gene expression in specific brain regions, reducing abnormal electrical activity and seizures.
Researchers at McMaster University have developed a targeted approach to treating IBD using bacteriophages, which selectively target harmful bacteria without disrupting the gut ecosystem. The phage therapy significantly reduced gut inflammation and enhanced the effectiveness of steroid treatments.
The University of Hong Kong's HKUMed team successfully introduced robot-assisted microsurgery, performing 48 procedures with no complications. The technology enhances precision and control, making it possible for more surgeons to perform intricate microvascular surgeries.
A new study found that clinician support significantly increases patient adoption of virtual reality therapies, leading to better time-based adherence and technology acceptance. The research team evaluated three implementation environments, with provider-led support demonstrating the most favorable usability pattern.
Researchers at Texas A&M University have developed a technique that maps chemical changes directly, using natural molecular vibrations. This allows for the observation of biological processes in real-time, giving researchers a more complete picture of how diseases emerge and evolve.
Researchers at the University of Pittsburgh developed a new imaging technique to visualize nerve patterns in densely innervated joints, such as the temporomandibular joint (TMJ). The c-Clear method produces a three-dimensional map of nerves with minimal tissue damage, allowing for better understanding of disorders like TMDs and TMJ pain.
Researchers have developed a microfluidic platform that recreates the complex ecosystem surrounding pancreatic tumors and observed how cells interact dynamically. The findings reveal a critical mechanism that may explain why many therapies fail and point to new therapeutic strategies.
Researchers will study blood samples and environmental exposures over 10 years to identify genetic, environmental, and cellular factors contributing to autoimmune diseases. The goal is to develop prevention strategies and treatments by understanding the earliest biological triggers of SARDs.
Researchers create custom-fit prosthetic hands with soft magnetic sensors that capture subtle changes in muscle shape and pressure. The system performs consistently and reliably, translating intent into control of a dexterous robotic hand with up to 90% accuracy.
A new imaging technology at UH helps scientists study exosomes, tiny particles released by human cells that may be targets for diseases. The technology uses advanced lighting at the nanoscale to analyze exosomes one at a time, measuring features to pinpoint good drug targets.
Researchers have discovered that advanced brain interfacing technology used for both touch and vision prostheses is almost identical, despite being developed separately. This breakthrough could lead to faster restoration of lost senses, including sight and motor function, with a unified technology that benefits both patient groups.
Scientists discovered a protein secreted by deep-sea extremophile Pyrodictium abyssi that self-assembles into a highly stable biofilm. This discovery opens new avenues for biomedical research and could lead to breakthroughs in wound dressing, medical device coatings, and tissue engineering.
Researchers developed a multi-functional biomaterial that eradicates residual cancer cells, prevents bacterial colonization, and regenerates missing bone tissue. Gallium oxide selectively targets bone cancer cells overexpressing transferrin receptors, causing cell death, while preventing infection in surgical sites.
New research reveals that asthma attacks cause overproduction of extracellular proteins and growth of blood vessels in the airways. Over time, these changes lead to constriction of breathing passages, resulting in long-term respiratory issues.
Hanyang University researchers developed AI-guided microneedle patches that actively change shape at physiological temperature to help close wounds while delivering regenerative therapy and antibacterial protection. The platform accelerates wound closure and improves tissue regeneration compared with conventional approaches.
Researchers developed a pH-triggered nanocomposite that synchronizes the release of therapeutic agents, combating bacterial biofilms and oxidative stress. The platform accelerates healing and promotes tissue repair in infected wounds.
Researchers at CNIC developed a technique to analyze proteins in individual cardiomyocytes, uncovering new clues about cardiac regeneration. The study found that the transcription factor Myc alters protein expression differently in each cell, generating regenerative potential in a subpopulation of cardiomyocytes.
A new wearable monitoring system called OMEGA aims to replace outdated fetal heart rate monitoring technology with a unified real-time assessment of fetal oxygen delivery and adaptive capacity. The system could potentially reduce C-section rates and improve maternal and fetal health outcomes, saving millions in healthcare costs.
Researchers developed a method combining AI and mathematical models to accelerate MRI scans for breast cancer imaging, achieving improved tumor visibility and high diagnostic sensitivity. The ELITE method has the potential to improve not only MRI scans but also other imaging platforms.
Researchers have developed a polymer-based microring resonator array with over 40 elements, demonstrating broadband acoustic detection and fine spatial resolution. The system achieved strong correspondence with biological structures, including blood vessel regions, in imaging mouse prostate tissue.
Researchers identify cholesterol ester buildup as biomarker predicting progestin therapy response in young women with endometrioid endometrial carcinoma. Combination treatment with progestin and a statin doubles six-month remission rate and helps patients become mothers.
Researchers found that over-the-counter probiotics contain only 36 unique species of bacteria, with most common species being forms of Lactobacillus. The analysis suggests a lack of consistency in the combination of species used to support gut health and vaginal health claims.
A new lab-on-a-chip platform, CellTrap, visualizes individual cell contacts to better understand the effectiveness of immunotherapies. The platform shows that early activation signals in immune cells indicate a cell-damaging effect later in cell-cell interactions.
Researchers at KAIST have developed a highly stretchable piezoelectric fiber sensor that operates stably even under repeated deformation. The sensor can be stretched up to 668%, generating consistent electrical signals under various movements, and is expected to enable long-term monitoring of biosignals in wearable medical devices.
A new study integrates robotic exoskeletons with therapist-patient interaction to create a more personalized and effective approach to stroke rehabilitation. The therapy, called TEPI, has been shown to improve joint range of motion, step length, and muscle activation compared to conventional therapy.
Researchers at Institute of Science Tokyo have developed a novel culture system to produce stable, scalable, and low-cost clinical-grade intestinal organoids from patient biopsy samples. The innovative approach uses clinical-grade collagen and synthetic peptides to enhance growth and improve scalability.
Researchers at Harvard's SEAS have developed a highly sensitive calorimeter that can detect metabolic heat signals on the order of 100 picowatts in living cells. The device tracks the growth of small populations of bacteria in real-time, including monitoring how bacterial growth changes in response to different antibiotics.
Researchers from ETH Zurich have developed a system that uses light to selectively destroy glucocorticoid receptors on tumour cells, making them vulnerable to attack. This approach could lead to more targeted and effective cancer treatments with fewer side effects.
Researchers developed a new approach to monitor HIV in communities by analyzing viral genomes in wastewater. The method strongly coincided with diagnosed HIV cases, suggesting that wastewater signals can track HIV burden.
A team of MIT engineers has created a tiny ingestible sensor that can measure temperature from within the body, offering continuous monitoring for patients who are sick or at risk of hypothermia. The device is small enough to be easily ingested and can provide accurate temperature readings with an accuracy of 0.01 degrees Celsius.
A $4 million NIH grant will help UC Davis researchers develop and test bioengineered grafts infused with ligands to treat neurogenic bladders in children. The grafts, designed to grow their own blood supply, have the potential to reduce complications after standard bladder augmentation surgery.
A new study published in Advanced Science shows that a programmable device can close complex wounds quickly, improving wound healing. The device uses customizable force to adapt to different wound shapes, promoting blood flow, nutrient delivery, and reduced scarring.
The review highlights advances in multi-scale bioelectrical interactions, analyzing challenges such as interface impedance and material-tissue compatibility. It emphasizes a shift towards application-driven design, integrating biological needs with material selection and device engineering.
Researchers find that limiting methionine in the diet destabilizes DNA organization and leads to cancer cell death and increased animal survival. The study proposes a new connection between diet, gene regulation, and cancer growth, opening possibilities for treating aggressive brain tumors.
Scientists developed a bioelectronic material called SIRES that maintains conductivity despite stretching up to 300%. The device can be attached to internal organs and provide stable performance even during movement. A new platform for implantable sensors also sticks to wet tissues while delivering therapeutic interventions.
A study by Baylor College of Medicine researchers identifies a set of dysfunctional genes and specific cell types that are vulnerable early on to genetic changes in Rett syndrome. The research reveals that even healthy cells can be influenced by their environment, contributing to widespread brain dysfunction in the disease.
Researchers create siRNA delivery system based on IVSA technology, which targets EGFR-positive tumors with high efficacy and low toxicity. The system enables precise targeting and overcomes drug resistance challenges.
A Texas A&M University biomedical engineering capstone team developed a pediatric jaw brace to help five-year-old David Hardy breathe at night. The device, called The JawDropper, successfully improved his breathing and was awarded a first-place prize among all biomedical teams.
A recent study published in Development reveals that the UTY gene on the human Y chromosome still contributes to transcriptional regulation during early development. Despite its low expression and reduced enzymatic activity, UTY co-occupies active regulatory elements with its X chromosome homolog UTX.
Researchers propose reconsidering how histone deacetylase inhibitors work in cancer treatment, identifying genuine molecular targets as a key step to improve treatment. The study suggests that HDAC inhibitors may interfere with other proteins, suppressing cancer growth.
Researchers summarize recent developments in terahertz biophotonics, highlighting its potential for overcoming technical limitations in fields like skin cancer diagnosis, wound assessment, and drug discovery. The study provides a roadmap for future research to improve the field's practical applications.
A POSTECH research team developed a haptic device that can operate inside MRI scanners, enabling the measurement of brain activity during VR experiences. The study found that adding tactile feedback increased brain activation in areas responsible for motor control, attention, and cognitive processing.
The RBA hydrogels can stretch to more than three times their original length while remaining mechanically stable. They were used as strain sensors to detect subtle facial movements and distinguish between walking, jogging, and running in real time.
A new framework, VIBEMed, uses multi-agent collaboration to break complex clinical decisions into specialist roles and employs a three-level self-evolution mechanism to improve performance over time. This approach demonstrates superior performance in complex medical reasoning and treatment planning tasks.
The university's patented technology assists surgeons in detecting and visualizing significant arterial bleeding using augmented reality overlays, enabling precise control and quick action. This innovation aims to improve patient outcomes, save lives, and reduce hospital stays, infection rates, and treatment costs.
Scientists at Linköping University have developed artificial heart muscle cells using organic electronics, opening up new possibilities for prosthetics, heart implants, and sensors. The technology aims to harness the principles of effective electrical signaling in biological cardiac muscle cells.
A novel biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin shows promising efficacy in treating periodontitis. The material has adhesive properties, allowing for targeted release of therapeutic compounds, and has been shown to promote regeneration of periodontal tissues.
A new monitoring system, NeuroSense, tracks cerebrospinal fluid at the bedside for faster intervention in intensive care units. The system detects biomarkers of infection and flow rate, enabling early warning of complications and better treatment decisions.
Researchers developed a novel fluorescent nanosensor to detect IPA, an emerging biomarker linked to gut health and disease. The sensor offers rapid detection within minutes, distinguishing IPA from closely related metabolites, enabling accurate measurement even in complex biological environments.
Researchers at MIT have created a pacemaker that uses ultrasound technology to stimulate the heart, offering a potential surgery-free alternative to traditional cardiac implants. The device is designed as a small sticker that sends ultrasound pulses through the chest to regulate heart contractions and correct arrhythmias.
Researchers found that traumatic occlusion combined with periodontitis leads to significant bone loss due to upregulated inflammatory pathways. The study suggests that excessive bite force does not directly cause damage but exacerbates existing dysregulation, making clinical applications of occlusal adjustment in treatment more relevant.
Researchers have developed custom 4D-printed implants that expand slowly and steadily, reducing the need for repeated injections and surgeries. The devices were tested in rabbits and showed promising results, including improved skin adaptation, reduced complications, and increased precision in reconstructive surgery.
A University of Michigan research team is exploring the development of knee exoskeletons to reduce joint contact forces and relieve osteoarthritis pain. Preliminary testing suggests that these orthotic brace-based exos and drone-style motors could provide significant relief.