Articles tagged with Biomedical Engineering
A new study published in Hernia examined 39 robotic hernia repairs, with most patients returning home after one day and no hernias recurring during follow-up. Robotic technology enables greater precision and flexibility, making complex operations less invasive and more effective.
A new framework proposes evidence sufficiency, selective prediction, and deferral pathways for multimodal AI in cardiovascular medicine. Missing data are not noise, but rather informative about patient state, clinician decisions, and health system access.
Researchers have successfully rejuvenated human cells in a test tube by directly reprogramming red blood cell precursors into stem cells from which neurons can be derived. This process resets the molecular clocks that indicate a cell's age, resulting in cells exhibiting a molecular age of less than 20 years.
Researchers developed a wristwatch-type sensor that integrates printed electrodes and wireless electronics for real-time monitoring of sodium and potassium in sweat. The device was successfully tested on a construction worker, acquiring and transmitting ion-responsive signals during normal work in the field.
A new AI tool has been developed to diagnose Ewing sarcoma with high accuracy, reducing errors and preserving tissue from biopsies. The tool achieves 91.6% accuracy and demonstrates a highly reliable solution to differential diagnosis among small round cell tumours.
Personalized medicines can improve dose accuracy and accessibility for patients with unique treatment needs, such as children and older adults with changing medication requirements. A new technology, inspired by 3D printing, enables mass production of customized treatments, increasing product quality and consistency.
Researchers propose matching sensing frequency to biomarker type and pairing with contextual data like blink patterns and tear flow to separate true biological change from normal fluctuations. The goal is to design sensors that can trust readings over time, moving beyond just counting biomarkers.
A new self-disinfecting cotton fabric has been developed to eliminate bacteria, fungi, and viruses in hospital settings. In laboratory tests, the fabric inactivated Escherichia coli within 60 minutes and Enterococcus faecalis within 20 minutes when exposed to light.
Researchers used AI to analyze 70 million cells and identified genes involved in autophagy and the immune system, including STING and GPHR. The study demonstrates the potential of combining AI with scalable image-based genetic screening to advance biological discovery.
The review highlights the importance of balancing mechanical support, biological activity and controlled degradation in bone regeneration. Silk fibroin-PLA composite scaffolds have shown improved cell responses, osteogenic activity, mechanical performance and tissue repair in experimental models.
A new system combines living bacteria with synthetic nanoparticles and a cancer drug to target bladder cancer cells. The treatment breaks down collagen in the tumor's matrix, allowing chemotherapy to penetrate and disrupt cancer cells.
A new device has been approved for a first human trial to treat cancer-related wasting, a severe and progressive syndrome affecting many patients with advanced cancer. The device, OnVagus, delivers noninvasive electrical stimulation to modulate the vagus nerve, aiming to preserve strength and quality of life during treatment.
A new study reveals molecular features linked to more aggressive prostate cancer in patients classified as low risk, highlighting biological differences that may not be apparent from clinical measures alone. The results could lead to new therapeutic strategies and more precise risk stratification.
Researchers developed a model to predict growth hormone therapy responses in children with short stature, incorporating changes in height percentile over time. The model estimated individual treatment responses and suggested personalized growth trajectories for better treatment planning.
A research team developed a workflow to quickly identify fungal pathogens from blood culture samples, generating genetic material for sequencing in real-time. The method achieved species-level identification within seven hours with high accuracy, detecting a range of fungal pathogens and mixed infections.
Researchers found that restoring IGFBP5 reduces stem cell senescence and enhances periodontal bone regeneration by activating WNT5B signaling. IGFBP5 overexpression improves cell survival and bone-forming ability in stressed stem cells, suggesting a potential therapeutic strategy for age-related periodontal bone loss.
The Terasaki Institute has been awarded $19.8 million to engineer transplantable, immune-compatible liver tissue, addressing a shortage of donor organs. The project, called Prometheus, aims to ease donor scarcity and the lifelong immunosuppression required by transplant patients.
Atrial fibrillation during sepsis is a common complication with no established treatment guidelines, linked to increased risks of stroke, death, and recurrence. The review highlights the need for a universally accepted definition, validated prediction models, and standardized anticoagulation strategies to manage this condition.
King's College London is co-leading a new partnership uniting London's health and care community to tackle pressing research priorities. The partnership will focus on four key areas: neighbourhood health, prevention, productivity, and data sciences for healthcare.
Pharmaceutical products can become contaminated with microorganisms, posing serious health risks. Sterilization processes vary in time and cost, with heat sterilization and gamma irradiation being traditional methods. Aseptic processing and sterile filtration are also used to produce sterile drug products.
Researchers are working on a four-year project to develop a personalized model that uses detailed blood flow information to detect obstructions in the aorta. The project aims to improve prenatal testing so that doctors can spot problems in the aorta before a baby is born and recommend treatments.
A University of Oxford-led study identified 20 priority areas for new respiratory health technology to improve care for people with chronic lung disease. The study found that existing solutions often lack equity, accessibility and usability, and that patients' needs should be built into technology development from the start.
Researchers aim to reduce ICU length of stay by 25% by creating personalized treatment plans using digital twins and real-time data analysis. The technology could revolutionize critical care by predicting disease progression and recommending effective treatment.
Researchers have developed biodegradable films from engineered honeybee silk, which can be programmed to respond to wound conditions. The material is safe, well-tolerated, and doesn't impede healing, making it a promising solution for preventing infections in chronic wounds.
A multidisciplinary team will integrate existing data to develop a computational framework predicting how vaginal tissue changes in response to hormones. The project aims to identify relationships between hormone dynamics and tissue microstructure and mechanics, ultimately improving women's health outcomes.
A new study found that while nutritional screening and dietitian involvement have increased, early oral feeding remains low, and total parenteral nutrition use is still high in China. This suggests that continued education and guideline promotion are needed to improve patient outcomes.
Researchers from CityUHK have developed a sequencing-free approach for spatial omics analysis, enabling routine clinical use. The method, Spectrum-FISH, preserves spatial information in freshly prepared tissue samples and offers advantages in affordability and scalability.
Researchers at Aarhus University have developed a tiny sensor that responds to touch in a similar way to our sensory cells. The sensor, made from a soft, silicone-like material, can convert touch into an electric potential and potentially stimulate nerves directly, allowing for prosthetic limbs with a sense of touch.
Zhen Xu, U-M Engineering professor, wins Golden Goose Award for development of histotripsy, a noninvasive cancer treatment. The technology has been used to treat over 5,000 patients worldwide and has the potential to treat various diseases, including brain diseases and cardiovascular diseases.
Researchers identified BRSK1 gene variants as a diagnosis for a rare neurodevelopmental disorder, characterized by developmental delays, neurological symptoms, and variable expressivity. Fruit fly studies connected the gene to the human condition, revealing essential role for BRSK1 in normal nervous system function.
Researchers have developed a laser-powered technology that accelerates antibody-antigen interactions to detect tiny amounts of a colorectal cancer biomarker within minutes. This technology has the potential to improve cancer diagnosis by increasing detection sensitivity and speed.
Researchers at MIT have developed a handheld device to collect living cells from specific locations in patient samples, enabling early cancer detection and personalized medicine development. The device uses a microfluidic channel to gently detach living cells from tissue, allowing for targeted sampling and cultivation for diagnostics a...
A University of California, Davis-led project aims to develop a 'cyborg' cell technology that can store and transport cellular therapies at room temperature, reducing costs and increasing accessibility. The CYBORGEL project, funded by up to $36.5M from ARPA-H, has the potential to make life-saving cell therapies more affordable and acc...
A novel wearable device, HELP, tracks breathing and heart activity using liquid-metal technology, enabling clinical-grade home monitoring for chronic respiratory and heart conditions. The patch features a unique analog constriction gate architecture, providing sensitivity and linearity across its entire physical range.
A UCF researcher and her team used AI to screen existing FDA-approved drugs for potential treatments of schwannoma tumors in children with Neurofibromatosis type 2. The research identified 10 promising candidates, with the most favorable targets stopping tumor cell growth by impacting different cellular mechanisms.
Researchers developed a gene-delivery system that converts reactive astrocytes into functional neurons, improving motor recovery in mice and rats. The system, TRANsCre-DIONE, selectively targets scar-forming cells and reprograms them into neurons, which generate nerve impulses and receive signals from other neurons.
Researchers identified a protein-degradation mechanism that contributes to the development of inherited CPVT, a disease that affects children and young people. The study suggests that inhibiting calpain, an enzyme involved in protein degradation, may restore normal heart function and reduce arrhythmias.
Researchers developed physics-embedded inverse learning (PEIL) to supervise parameter estimation in wireless communications and MRI. PEIL uses signal recovery to estimate intermediate parameters without labels, achieving strong symbol recovery and comparable performance to parameter-supervised baselines.
Recent advances in engineered mitochondrial delivery aim to improve stability, efficiency, and precision of mitochondrial transplantation. Four strategies have been proposed, including surface-engineering, cell-mediated delivery, vesicle-encapsulation, and cell-type-specific targeting.
A team of researchers has developed nanoparticles that can activate nerve cells in degenerated retinas, potentially leading to a new type of retinal prosthesis. The nanoparticles, made from graphitic carbon nitride, trigger electrical and chemical processes that activate nerve cells and prompt signals towards the brain.
The grant will support research experiences for 12 WPI undergraduates in Solomon Mensah's lab, aiming to determine the molecular mechanisms behind sepsis-induced blood clotting. The goal is to rescue a damaged glycocalyx barrier, paving the way for sepsis treatments.
The Terasaki Institute faculty has developed a next-generation immunomodulatory wound dressing platform designed to accelerate healing in chronic wounds. The platform is designed to deliver oxygen directly to the wound and use a specialized peptide to encourage immune cells to support healing.
A review in Biomedical Analysis highlights the integration of microfluidic technologies to bring flow cytometry closer to point-of-care testing, enabling blood cell counting, leukocyte differential analysis, and imaging-based white blood cell classification
Finalists in the 2026 Blavatnik National Awards for Young Scientists have been recognized for their groundbreaking research in Life Sciences, Chemical Sciences, and Physical Sciences & Engineering. The 18 Finalists will compete for three $250,000 Laureate prizes, with the remaining 15 receiving $15,000. The Awards aim to support innova...
The University of Rhode Island Biomedical Engineering department has received a $1.015 million NIH grant to develop a multimodal neurotechnology framework for understanding and enhancing motor brain function. The project will integrate electroencephalography, functional near-infrared spectroscopy, and behavioral measurements to investi...
Researchers develop a new approach combining probiotics with T cells to improve tumor localization and coordination of local immune responses. The therapy, called T-FOLactis, shows improved tumor control and median survival in mouse colorectal cancer models.
A portable handheld terahertz three-dimensional spectral scanner has been developed to diagnose burn wounds and predict wound-healing outcomes. The device uses an asynchronous optical sampling system to achieve short scan times and can acquire three-dimensional spectroscopic images in the terahertz range.
A Korea University study investigated plasma p-tau217 as an early marker of treatment response in early Alzheimer's disease. The study found that patients with greater reductions in p-tau217 levels had more favorable cognitive trajectories.
A new brain-computer interface (BCI) allows people with vocal tract and bodily paralysis to convey both speech and upper-body gestures simultaneously. The BCI successfully translated the thoughts of patients into commands that dictated the expressions of a full-body virtual avatar.
Researchers developed a new culture membrane that recreates the biochemical composition and soft physical environment of native intestinal tissue, enhancing intestinal cell growth and behavior. The membrane, combined with human colon organoid-derived epithelial cells, exhibited increased characteristics associated with intestinal stem ...
Professor Shin's research focuses on developing tissue-adhesive, electrically conductive hydrogels for muscle and brain tissue repair. Her AYSF-supported project aims to engineer an injectable hydrogel filler for brain tumor recovery, addressing the limited capacity for neural tissue regeneration in the adult brain.
Researchers at CU Anschutz have developed CAR T-cell therapy to target two pathways that help colorectal tumors grow and evade the immune system, B7-H3 and IL-8. The therapy aims to provide a more durable response than traditional chemotherapy.
A new saliva-based assay rapidly and accurately assesses flavivirus immunity by measuring multiple antibody classes in saliva. The test can distinguish between individuals with polytypic dengue virus immunity and those who have previously experienced both dengue virus and Zika virus infections.
Researchers developed a device called MetaboSense that continuously tracks key indicators of lung health, providing transplant teams with more detailed information than current hourly testing. The technology could help identify more viable donor lungs and potentially rehabilitate organs that might otherwise be rejected.
Researchers have developed a technology that combines aminoglycoside antibiotics with PKZ18 analogs, resulting in up to an 8-fold increase in efficacy and reduced risk of microbial resistance. This synergy enables targeting of bacteria in various environments, expanding the therapeutic window.
Researchers developed a biodegradable metal-polymer composite stent that outperforms traditional stents in a 5-year clinical trial involving 1,108 patients. The stent's polymer coating reduces inhomogeneity of degradation but increases corrosion rate, leading to faster degradation and later device fracture.
This DNA nanoswitch technology detects RNases using a simple mix-and-read methodology, offering a cost-effective solution for biological samples. The nanoswitch changes shape in response to RNase presence, making it a useful tool for RNase-sensing applications.
A novel laser-fabricated plasmonic chip combines 185 nm Raman resolution with deep learning to identify and sort cancer cells. The developed sorter achieves precise cell sorting without labeling, using spatially resolved Raman signals.
Researchers discovered that β1 integrin and DDR2 form a cooperative collagen-sensing system in skeletal progenitor cells, regulating their migration, proliferation, and differentiation during bone regeneration. Targeting both receptors may provide a more effective strategy for enhancing bone repair in degenerative or injury-related ske...
A new method uses hybrid bright-dark field imaging to enhance digital pathology resolution, improving diagnostic sensitivity and AI-assisted analysis. It achieves 2.1x spatial resolution enhancement with minimal hardware upgrades and improved efficiency.