Articles tagged with Biomedical Engineering
The US Naval Research Lab is developing continuous biomanufacturing technologies to produce critical materials more efficiently and sustainably. The approach uses surface-bound microbial cells to generate valuable compounds over extended periods, reducing energy requirements and equipment size.
Researchers have developed a novel method to control miniature rotations using water flow at a surface, allowing for the creation of targeted ultrafine structures such as twisted fibers for wires and sutures. This approach enables the assembly of complex structures without mechanical contact or chemical propulsion systems.
JMIR Publications is sponsoring the upcoming BioMedEng26 conference to promote biomedical engineering innovation. The journal JMIR Biomedical Engineering will be highlighted during the event, with Dr. Javad Sarvestan discussing its focus on cutting-edge engineering applications and peer-review process.
Scientists at UVA have developed a new method to target glioblastoma, the most common and deadly brain cancer, by delivering microRNAs through the brain's natural barrier. The approach shows promise in slowing tumor growth and extending survival in animal models.
Researchers at Science Tokyo develop a Ramsey-based magnetometer that overcomes thermal limitations, enabling close-proximity detection of weak biomagnetic signals. The sensor achieves high sensitivity and safe operation near biological tissue.
A UMass Amherst-led team is developing a new approach to prevent bladder cancer recurrence by exfoliating the bladder lining. The technology uses irreversible electroporation to target premalignant cells, offering a potential alternative to surgical removal or aggressive treatments.
A new model, PSIDMViT, combines anatomy, physics, and machine learning to predict accurate dose distributions for CyberKnife radiation therapy. The study shows improved agreement with Monte Carlo reference doses and reduced computation time, suggesting a promising strategy for improving radiotherapy dose prediction.
Researchers identified simple changes to surgical tools that can significantly affect how pressure is distributed across the esophageal wall during neck surgery. Wider retractor blades reduced stress beneath the center of the blade by up to 82%, but also shifted higher stress toward the edges.
Researchers have identified a widespread source of error in a popular genome study method and created a machine-learning tool to correct it. PATTY uses machine learning to reduce artifacts while preserving real signals in noisy data, giving researchers a clearer view of gene activity control.
The study reveals that different forms and levels of partner proteins involved in the disease lead to distinct molecular interactions and biological outcomes in different tissues. The findings suggest that directing therapies to specific protein forms may improve treatment options for neurological diseases.
A research team developed a walking-support robot that uses large-area tactile contact at the torso to track movement intent and share load. The system continuously adapts as the coupled human-robot dynamics evolve, allowing intention alignment and balance support to emerge from the same physical channel.
A new study published in Chinese Neurosurgical Journal found that real-time MRI and brain function monitoring during neurosurgery can improve the removal of tumors affecting the corpus callosum more effectively and safely. This multimodal approach gave patients about 30 extra months after treatment before the tumor grew back or worsene...
University of Oregon researchers engineer molecules and control regenerative cue release to improve healing outcomes for complex injuries. A staggered sequence approach shows better blood vessel regeneration, and the method is being applied to bone healing, muscle repair, and spinal cord regeneration.
Researchers found subtle patterns in brain activity while children listened to speech linked to verbal communication abilities in autistic youths. Altered brain signals suggested the brain may process speech less efficiently, with noisier signals associated with lower scores on everyday verbal communication.
Researchers at Baylor College of Medicine identified a vulnerability in triple-negative breast cancers with LIG1 loss and used it to develop a new therapy for chemotherapy-resistant TNBC tumors. A combination of olaparib and ceralasertib showed significant effectiveness in reducing tumor growth in animal models.
A study by Pompeu Fabra University, ONT, and Vall d'Hebron Hospital reveals that public investment in liver transplants not only improves patient survival but also generates a positive social and economic return. The study estimates that liver transplant patients contribute over 100 million euros to the Spanish economy annually.
A novel biological pathway has been uncovered that can lead to seizures when disrupted, providing a new approach for improved diagnosis. The study identifies an association between defective genes and increased glutamatergic transmission, which can increase the risk of seizures.
Researchers at MIT have created a precise way to engineer artificial blood vessels by mechanically stretching and pulling a "blood vessel on a chip". The new method, reported in the Proceedings of the National Academy of Sciences, enables controlled sprouting of new vessels and programming of their growth patterns.
A new award will help advance the proof-of-concept work toward commercialization of an at-home HIV test that detects cases not caught by lab tests. The device, called Click Chemistry Amplified Nanopore (CAN) sensing, has shown promising results in early studies.
Researchers developed DeepHHF, an AI model that identifies patients at high risk of heart failure up to five years in advance. The model analyzes standard ECG recordings and detects subtle abnormalities that are often imperceptible to the human eye.
Researchers developed a hybrid technology combining human learning and machine learning in noninvasive BCIs, producing rapid and sustained gains in motor imagery control. The study demonstrates significant scientific and technological advancement in BCIs, establishing a scalable pathway toward robust neural interfaces.
Flexible electromagnetic induction-type tactile sensors offer a promising route for low-power, robust and self-powered interfaces. The researchers provided a systematic roadmap for development, including application-oriented design and multimodal integration with other sensing mechanisms.
Researchers at Terasaki Institute develop a wireless dual-compartment biochemical monitoring platform for real-time tracking of key biomarkers in perfusion fluid and bile during normothermic machine perfusion. The study shows improved interpretation of post-transplant outcomes with combined bile and perfusate data.
Researchers developed nanoparticles that retain their protective coating in normal tissue but shed it upon reaching tumor tissue, releasing anticancer drugs. This technology reduces systemic side effects and enhances treatment efficacy.
Experts recommend implementing safer technologies and modernizing radiation safety standards to reduce preventable radiation exposure and orthopedic injuries. The consensus statement emphasizes the need for mandatory action to prioritize protecting healthcare workers, ensuring a healthy workforce for patients' access to lifesaving care.
Researchers at Penn State have developed paint-on tattoos that can power sensors and track health data like heart rate and brain waves. The innovative conductive ink can be customized with various colors and designs, providing a comfortable and accurate wearable solution.
A novel gene promoter called cmGAD67 shows promise for treating drug-resistant epilepsy by selectively stimulating inhibitory neurons. The study found that the promoter drove strong and highly selective gene expression in specific brain regions, reducing abnormal electrical activity and seizures.
Baylor researchers developed a novel method of somatic gene editing in mice to generate tumor models. The new rat models closely mimic human disease biology, response to therapy and immune microenvironment, offering a powerful way to study cancers not well studied in mouse models.
Researchers at McMaster University have developed a targeted approach to treating IBD using bacteriophages, which selectively target harmful bacteria without disrupting the gut ecosystem. The phage therapy significantly reduced gut inflammation and enhanced the effectiveness of steroid treatments.
Researchers at Texas A&M University have developed a technique that maps chemical changes directly, using natural molecular vibrations. This allows for the observation of biological processes in real-time, giving researchers a more complete picture of how diseases emerge and evolve.
Researchers at the University of Pittsburgh developed a new imaging technique to visualize nerve patterns in densely innervated joints, such as the temporomandibular joint (TMJ). The c-Clear method produces a three-dimensional map of nerves with minimal tissue damage, allowing for better understanding of disorders like TMDs and TMJ pain.
The University of Hong Kong's HKUMed team successfully introduced robot-assisted microsurgery, performing 48 procedures with no complications. The technology enhances precision and control, making it possible for more surgeons to perform intricate microvascular surgeries.
A new study found that clinician support significantly increases patient adoption of virtual reality therapies, leading to better time-based adherence and technology acceptance. The research team evaluated three implementation environments, with provider-led support demonstrating the most favorable usability pattern.
Researchers have developed a microfluidic platform that recreates the complex ecosystem surrounding pancreatic tumors and observed how cells interact dynamically. The findings reveal a critical mechanism that may explain why many therapies fail and point to new therapeutic strategies.
Researchers will study blood samples and environmental exposures over 10 years to identify genetic, environmental, and cellular factors contributing to autoimmune diseases. The goal is to develop prevention strategies and treatments by understanding the earliest biological triggers of SARDs.
A new imaging technology at UH helps scientists study exosomes, tiny particles released by human cells that may be targets for diseases. The technology uses advanced lighting at the nanoscale to analyze exosomes one at a time, measuring features to pinpoint good drug targets.
Researchers create custom-fit prosthetic hands with soft magnetic sensors that capture subtle changes in muscle shape and pressure. The system performs consistently and reliably, translating intent into control of a dexterous robotic hand with up to 90% accuracy.
Researchers have discovered that advanced brain interfacing technology used for both touch and vision prostheses is almost identical, despite being developed separately. This breakthrough could lead to faster restoration of lost senses, including sight and motor function, with a unified technology that benefits both patient groups.
Scientists discovered a protein secreted by deep-sea extremophile Pyrodictium abyssi that self-assembles into a highly stable biofilm. This discovery opens new avenues for biomedical research and could lead to breakthroughs in wound dressing, medical device coatings, and tissue engineering.
Researchers developed a multi-functional biomaterial that eradicates residual cancer cells, prevents bacterial colonization, and regenerates missing bone tissue. Gallium oxide selectively targets bone cancer cells overexpressing transferrin receptors, causing cell death, while preventing infection in surgical sites.
New research reveals that asthma attacks cause overproduction of extracellular proteins and growth of blood vessels in the airways. Over time, these changes lead to constriction of breathing passages, resulting in long-term respiratory issues.
Hanyang University researchers developed AI-guided microneedle patches that actively change shape at physiological temperature to help close wounds while delivering regenerative therapy and antibacterial protection. The platform accelerates wound closure and improves tissue regeneration compared with conventional approaches.
Researchers developed a pH-triggered nanocomposite that synchronizes the release of therapeutic agents, combating bacterial biofilms and oxidative stress. The platform accelerates healing and promotes tissue repair in infected wounds.
Researchers at CNIC developed a technique to analyze proteins in individual cardiomyocytes, uncovering new clues about cardiac regeneration. The study found that the transcription factor Myc alters protein expression differently in each cell, generating regenerative potential in a subpopulation of cardiomyocytes.
Researchers developed a method combining AI and mathematical models to accelerate MRI scans for breast cancer imaging, achieving improved tumor visibility and high diagnostic sensitivity. The ELITE method has the potential to improve not only MRI scans but also other imaging platforms.
A new wearable monitoring system called OMEGA aims to replace outdated fetal heart rate monitoring technology with a unified real-time assessment of fetal oxygen delivery and adaptive capacity. The system could potentially reduce C-section rates and improve maternal and fetal health outcomes, saving millions in healthcare costs.
Researchers identify cholesterol ester buildup as biomarker predicting progestin therapy response in young women with endometrioid endometrial carcinoma. Combination treatment with progestin and a statin doubles six-month remission rate and helps patients become mothers.
Researchers have developed a polymer-based microring resonator array with over 40 elements, demonstrating broadband acoustic detection and fine spatial resolution. The system achieved strong correspondence with biological structures, including blood vessel regions, in imaging mouse prostate tissue.
Researchers found that over-the-counter probiotics contain only 36 unique species of bacteria, with most common species being forms of Lactobacillus. The analysis suggests a lack of consistency in the combination of species used to support gut health and vaginal health claims.
A new lab-on-a-chip platform, CellTrap, visualizes individual cell contacts to better understand the effectiveness of immunotherapies. The platform shows that early activation signals in immune cells indicate a cell-damaging effect later in cell-cell interactions.
A new study integrates robotic exoskeletons with therapist-patient interaction to create a more personalized and effective approach to stroke rehabilitation. The therapy, called TEPI, has been shown to improve joint range of motion, step length, and muscle activation compared to conventional therapy.
Researchers at KAIST have developed a highly stretchable piezoelectric fiber sensor that operates stably even under repeated deformation. The sensor can be stretched up to 668%, generating consistent electrical signals under various movements, and is expected to enable long-term monitoring of biosignals in wearable medical devices.
Researchers at Institute of Science Tokyo have developed a novel culture system to produce stable, scalable, and low-cost clinical-grade intestinal organoids from patient biopsy samples. The innovative approach uses clinical-grade collagen and synthetic peptides to enhance growth and improve scalability.
Researchers at Harvard's SEAS have developed a highly sensitive calorimeter that can detect metabolic heat signals on the order of 100 picowatts in living cells. The device tracks the growth of small populations of bacteria in real-time, including monitoring how bacterial growth changes in response to different antibiotics.
Researchers developed a new approach to monitor HIV in communities by analyzing viral genomes in wastewater. The method strongly coincided with diagnosed HIV cases, suggesting that wastewater signals can track HIV burden.
A team of MIT engineers has created a tiny ingestible sensor that can measure temperature from within the body, offering continuous monitoring for patients who are sick or at risk of hypothermia. The device is small enough to be easily ingested and can provide accurate temperature readings with an accuracy of 0.01 degrees Celsius.
Researchers from ETH Zurich have developed a system that uses light to selectively destroy glucocorticoid receptors on tumour cells, making them vulnerable to attack. This approach could lead to more targeted and effective cancer treatments with fewer side effects.
A $4 million NIH grant will help UC Davis researchers develop and test bioengineered grafts infused with ligands to treat neurogenic bladders in children. The grafts, designed to grow their own blood supply, have the potential to reduce complications after standard bladder augmentation surgery.
A new study published in Advanced Science shows that a programmable device can close complex wounds quickly, improving wound healing. The device uses customizable force to adapt to different wound shapes, promoting blood flow, nutrient delivery, and reduced scarring.
Researchers find that limiting methionine in the diet destabilizes DNA organization and leads to cancer cell death and increased animal survival. The study proposes a new connection between diet, gene regulation, and cancer growth, opening possibilities for treating aggressive brain tumors.