Researchers at Tufts University School of Medicine discovered biomarkers that could help clinicians better detect and possibly cure early and persistent Borrelia burgdorferi infections. Anti-lipid antibodies, such as anti-phosphatidic acid and anti-phosphatylserine, may indicate new Lyme disease infections or persistent symptoms after ...
Scientists developed a new population model, APODEMUS, to predict pesticide effects on animal populations. The model simulates complex agricultural landscapes and foraging scenarios, tracking energy conversion and exposure to pesticides.
Prof. Yehu Moran's election to EMBO recognizes his groundbreaking research on the evolution of biological defense systems, advancing our understanding of life and exemplifying the university's scientific excellence.
A study found that parole candidates from diverse racial backgrounds are evaluated differently based on cultural frames used to explain their crimes. Participants preferred dispositional statements, while those from interdependent cultures chose situational factors equally or with equal frequency.
Researchers surveyed 503 Americans on news headline accuracy and confidence. They found that people with high confidence in specific judgements were better at distinguishing true from false headlines, whereas those with general overconfidence struggled with this task.
A chatbot using GPT-4o technology delivers personalized messages to American adults, increasing support for transgender rights and improving attitudes, but effects are short-term. The intervention demonstrates AI's potential as a scalable complement to community-based approaches aimed at fostering inclusion.
A new method uses machine-learning algorithms to detect scatterable PFM-1 landmines over wide areas, providing a first-pass analysis of suspected hazardous areas. The technique requires only a lightweight laptop, drone, and camera, operating without an internet connection.
A recent poll found that Orange County residents generally trust their local institutions, with 60% trusting the police department and 25% trusting the federal government. However, Independents express skepticism towards county government at just 32%, highlighting a concerning trend in the civic landscape.
A genomic study found two previously unreported truncating germline variants in BRCA2, suggesting inherited alterations may contribute to susceptibility to multiple primary lung cancers. The study also points toward important clinical applications, including the use of PARP inhibitors and molecularly targeted approaches for treatment.
A study by University of Basel researchers found that farming in Switzerland increased plant diversity over the past 7000 years. However, this trend reversed with modern agriculture's emphasis on efficiency and uniformity. The data suggests that altering farming practices could reverse declining biodiversity.
A new AI model, SpliceSelectNet, accurately predicts RNA splicing by capturing long-range DNA signals. The model's hierarchical Transformer architecture preserves high computational efficiency while maintaining single-nucleotide resolution, enabling accurate analysis of genomic regions.
Researchers at UT San Antonio develop non-toxic biologic to prevent Lyme disease transmission. The treatment targets small mammals and birds, reducing bacterial loads in ticks, and may soon be available for residential use.
Researchers at University of Toyama found three risk factors for mother-infant bonding disorders: difficulty holding a fussy baby, low happiness about pregnancy, and lack of social support. These factors predict increased risks of developmental delays and child abuse.
Researchers aim to develop reliable power generation in harsh environments, including space and underwater settings, using perovskite solar cells. Advances in material composition and device engineering can overcome instability issues, enabling long-term reliability and performance.
Prof. Orly Lewis is developing a flexible publishing platform for interactive knowledge environments, while Prof. Nir Friedman is creating an epigenomic liquid biopsy for early detection and monitoring of Metabolic Dysfunction-Associated Steatohepatitis.
A team of UTEP researchers has created a printable gel polymer electrolyte that can be 3D-printed in any shape. The material performed similarly to conventional electrolytes and showed optimal performance at a specific recipe ratio, paving the way for flexible battery design.
Researchers found that diapause eggs exhibit increased chromatin remodeling, reduced gene expression for neural development, and enhanced metabolism. This study sheds light on the developmental mechanisms underlying insect diapause, a survival strategy for cold temperatures.
Acute myeloid leukemia transforms lung tissue into an inflammatory environment that promotes tumor cell expansion and impairs respiratory function. Researchers identified galectin-9 and the IL-33/IL1RL1 axis as potential targets for reducing this serious complication.
Biomedical engineers at Duke University have successfully grown specialized blood vessel cells critical to retinal health from induced pluripotent stem cells. These 'retinal endothelial cells' integrated into damaged tissue to regenerate blood vessels, restore function, and form functional vascular tissue in a lab-grown environment.
Researchers at ASHBi, Kyoto University, discovered that embryonic cells use tissue boundaries and cell interactions to organize themselves. Cells near the VE turned to face perpendicular to it, while those near ExE lay flat and parallel to the boundary.
A Phase I trial evaluated a novel multi-targeted T-cell therapy for children with deadly brain tumors, offering early evidence that the patient's own immune cells can reach and fight tumors while producing fewer severe side effects. The study suggests a safer and more effective approach for pediatric brain cancers.
Computer scientists have developed a new AI tool called RNAbpFlow that can map RNA structures with high accuracy, rivaling Google's AlphaFold 3. The method uses flow matching and can generate complete 3D structures from scratch, making it useful for drug discovery and targeting specific RNA folds.
Scientists have discovered a rare genetic condition called Heyn-Sproul-Jackson syndrome (HESJAS) that causes people to age at an accelerated rate. DNA methylation marks accumulate over time and can accurately measure a person's age, but in HESJAS, these marks occur at a much quicker rate, connecting to multiple age-related disease proc...
Researchers have created a novel Pt-Fe bimetallic catalyst that exhibits remarkable catalytic metrics, maintaining propylene selectivity over 95% and regenerability. The framework anchoring effect of iron species suppresses thermal sintering of Pt centers, ensuring atomic dispersion under high-temperature conditions.
A new ruthenium nanoparticle catalyst supports on a nitrogen-doped carbon framework enables stable and efficient hydrogen production. The design incorporates spatial confinement, anchoring sites, and electronic modulation to facilitate alkaline HER performance.
Researchers have discovered that advanced brain interfacing technology used for both touch and vision prostheses is almost identical, despite being developed separately. This breakthrough could lead to faster restoration of lost senses, including sight and motor function, with a unified technology that benefits both patient groups.
Researchers use cryo-electron microscopy to reveal the 3D structure of Mfa pili in P. gingivalis, understanding its role in attaching to host tissues and other microbes. This information can aid in developing therapeutic strategies to block attachment and infection.
A systematic review found that creatine monohydrate may reduce depressive symptoms in people taking standard antidepressants, with two trials showing significant benefits. However, three trials showed no effect, and the evidence is not yet settled due to limitations such as small sample sizes and biased patient enrollment.
A new analysis model predicts plastic deformation behavior of sheet metals based on microstructural characteristics, reducing calculation time from hours to seconds. The technology improves process design efficiency for automotive and battery applications by predicting forming issues like tearing and wrinkling.