Articles tagged with Biomedical Engineering
A new platform combines bacteria and viruses to target cancer cells. The system hides a virus inside a tumor-seeking bacterium, smuggling it past the immune system and unleashing it inside cancerous tumors.
University of Houston researchers are developing an AI-powered dashboard for Florida food pantries, aiming to streamline stakeholder collaboration and distribute resources to families in need. The tool will enable emergency coordinators to respond quickly to spikes in demand, prioritizing the needs of vulnerable populations.
Researchers at the Institute of Molecular and Clinical Ophthalmology Basel discovered that differences in nerve signal speed and distance are actively balanced within the human eye to support a unified visual experience. This mechanism helps align signal arrival times to just a few milliseconds, contributing to synchronization.
A low-cost UAV imaging technique has been developed to accurately assess wheat plant height, revealing subtle variations and stable genetic loci. This method enhances the efficiency of marker-assisted selection in wheat breeding programs, offering a scalable tool for phenotyping plant height and improving crop yields.
Researchers developed an alginate-based microrobot that can be tracked using Magnetic Particle Imaging (MPI) and performs real-time localization, selective thermal therapy, and cell delivery. The robot is powered by a single magnetic actuation system independent of conventional medical imaging devices.
Researchers have developed a next-generation wireless ophthalmic diagnostic technology incorporating an ultrathin OLED into a contact lens. This breakthrough simplifies the conventional ophthalmic diagnostic environment, allowing patients to undergo retinal function tests while wearing the lens.
Researchers at Arizona State University have developed a rapid and accurate diagnostic test called NasRED that can detect diseases like COVID-19 with high sensitivity. The test uses tiny gold nanoparticles to identify disease-related proteins in a sample of bodily fluid, providing lab-quality accuracy without expensive equipment.
The new handbook provides a practical approach to harnessing zebrafish as a model organism for biomedical research, covering drug efficacy evaluation and disease mechanisms. It offers step-by-step experimental protocols and theoretical grounding for researchers of all levels.
Scientists at Yokohama National University have created a device that uses acoustic levitation and a squeeze film to move objects without friction, enabling fast and precise transport of small parts. The device was tested on an inclined surface and showed successful movement with weights up to 43 grams.
Researchers have developed an AI system that can recognize the early warning stages of laryngeal cancer from voice recordings. By analyzing variations in tone, pitch, and volume, the AI can distinguish between voices with benign vocal fold lesions and those with cancer. The study's findings offer a promising breakthrough for non-invasi...
Researchers have engineered CalBots, magnetic nanobots that can penetrate dentinal tubules and form durable seals, offering lasting relief from sensitivity. The study uses a new class of bioceramic cement to create a regenerative, active nanomaterial with potential implications for future healthcare.
A UCLA team has uncovered new details about the muscle controlling blinking, offering a pathway toward developing blink-assisting prostheses. The orbicularis oculi muscle contracts in complex patterns that vary by action and move the eyelid in more than just a simple up-and-down motion.
Researchers developed an organic molecule that simultaneously emits light suitable for displays and absorbs photons for deep-tissue bioimaging, overcoming a long-standing design challenge. The compound achieved high efficiency in both applications, paving the way for next-generation multifunctional materials.
Physicists from the IFJ PAN in Cracow have successfully produced homogeneous coatings of titanium oxide nanotubes on large metal surfaces, overcoming the obstacle of crystal grain boundaries. The method combines nanoparticle lithography and electrochemical anodization, enabling controlled material properties.
Silvia Blemker, a renowned biomedical engineer, has been elected to lead the American Society of Biomechanics. She aims to bolster industry ties, expand funding for students and early-career researchers, and promote interdisciplinary collaboration.
Researchers found that bystander CAR-negative CD8+ T cells expanded after CAR-T cell therapy and propagated with bispecific antibody treatment, leading to complete tumor remission. This study supports a new therapeutic effect of bystander T cells in combination with CAR-T and BsAb therapies.
Scientists have developed a breakthrough method to grow human kidney organoids from tissue stem cells, mirroring fetal kidney development over months. The organoids can be used for research and testing of new treatments for kidney diseases.
Scientists at UChicago Pritzker Molecular Engineering have developed polymer-based nanoparticles that self-assemble at room temperature in water, enabling stable delivery of proteins and RNA. These versatile particles can be used to carry various biologic drugs, including vaccines, with high efficiency and scalability.
Researchers have discovered a specialized mesenchymal-endothelial crosstalk that supports angiogenesis and osteogenesis, enabling periodontal bone regeneration. This communication network between mesenchymal stem cells and endothelial cells drives tissue repair and regeneration, holding promise for dental therapeutic strategies and bro...
Researchers at Washington University in St. Louis have successfully induced a reversible torpor-like state in mice using focused ultrasound, offering a novel strategy for medical interventions. This technology aims to reduce energy demand and preserve organs for transplantation, promising to transform medicine.
A team of researchers is using NCSA resources to simulate the long-term progression of atrial fibrillation, a type of irregular heartbeat. By modeling the heart's electrical activity, they have uncovered a vicious cycle where adaptations to maintain calcium balance lead to continued arrhythmias and eventually a permanent condition.
Researchers discovered that magnetized surfaces significantly influence amyloid protein assembly, forming more fibrils and longer structures when aligned in one direction. The study suggests a new physical factor, Chiral-Induced Spin Selectivity (CISS), plays a direct role in protein self-assembly.
The journal is seeking high-quality submissions that explore the potential of voice and speech analysis in diverse medical applications. Submissions focus on acoustic and voice analysis techniques, voice or vocal phenotyping, and vocal biomarkers in health and medicine.
A low-cost 'SimpleSilo' device mimics commercial silo bags without high cost, using inexpensive materials and easy-to-source supplies. The device demonstrated comparable performance to commercial silo bags and can be assembled by hospital staff in under an hour.
Researchers from the Institute of Physics of the Czech Academy of Sciences studied the biological effects of permanent magnetic fields and found that their distribution in space plays a critical role in healing. The study's detailed field maps offer practical guidance for optimizing magnet use in medicine and magnetobiology.
Researchers found that combining lavender essential oil with its own hydrosol effectively preserves skin-care emulsions against bacteria and fungi. The simple pairing kept counts below European Pharmacopoeia limits, even at high temperatures.
Researchers at Chiba University have developed novel microfluidic devices that incorporate microcones to detect and characterize circulating tumor cells in blood. The devices demonstrated highly selective capture of human breast and lung cancer cells, with high efficiency even at high flow rates.
A new sleep algorithm developed by KAIST researchers helps users build healthy sleep habits by recommending the best bedtime based on their body's circadian rhythm. The algorithm is available on Samsung Galaxy smartwatches and aims to improve sleep quality and overall well-being.
Engineers at RMIT University have developed a new low-cost approach to creating 3D-printed titanium alloys, which are about a third cheaper than standard alloys. The new alloy has improved strength and performance compared to traditional 3D-printed titanium alloys.
A new silicone patch with star-shaped microneedles, called the ExoPatch, distinguishes melanoma from healthy skin in mice, capturing cancer biomarkers from exosomes. The test shows promise for early detection of the most aggressive form of skin cancer without a biopsy or blood draw.
Researchers have demonstrated a novel vaccine delivery method using dental floss, which stimulates the production of antibodies in mucosal surfaces, such as the lining of the nose and lungs. This technique has shown superior antibody response compared to current oral vaccination methods.
Researchers designed a hydrogel system using milk-derived extracellular vesicles as both bioactive cargo and structural building blocks, enabling tissue engineering and regenerative medicine applications. The yogurt EVs promote healing and tissue regeneration without additional chemical additives.
Researchers developed an AI platform to design proteins that arm immune cells to attack and kill cancer cells. The method reduces the process from years to just 4-6 weeks, offering a new approach to precision cancer treatment.
Bonn researchers reduce cardiac arrhythmia after heart attacks by using gene therapy to overexpress connexin 43 in fibroblasts of cardiac scar tissue, leading to improved electrical connection between cells and reduced arrhythmias.
Researchers adapted optical coherence tomography (OCT) to visualize tiny structures in the human inner ear, correlating fluid levels with a patient's degree of hearing loss. The findings may help clinicians diagnose and treat hearing loss more quickly and effectively.
The article highlights the need for improved sepsis diagnosis, personalized treatment, and innovative trial designs. It advocates for a multifaceted approach integrating timely diagnosis, tailored therapy, and equitable implementation to tackle the global burden of sepsis.
Researchers developed a high-throughput phenotyping pipeline to analyze maize root development across genotypes, revealing extensive variability in root morphology and transcriptional profiles. Transcriptomic analysis identified thousands of differentially expressed genes related to hormone signaling, stress response, and cell wall org...
Researchers have developed a mechanical adhesive device that can attach to soft surfaces underwater, inspired by the hitchhiking sucker fish. The device uses pressure-based suction and has enhanced adhesion capabilities, making it suitable for delivering drugs in the GI tract or monitoring aquatic environments.
A study published in Journal of the Mechanical Behavior of Biomedical Materials found that wrinkled skin is caused by its tendency to buckle under pressure due to age-related changes in its mechanical properties. As people age, their skin becomes more prone to wrinkles as it stretches and contracts in different directions.
Researchers at MURR have optimized Terbium-161 for radiopharmaceutical use, enabling targeted destruction of cancer cells with high-energy electrons. The breakthrough could add extra therapeutic effectiveness to existing treatments without requiring new drug development.
Bioengineers at Harvard John A. Paulson School of Engineering and Applied Sciences have developed a computational model called BrainFlow that simulates cerebrospinal fluid flow in the presence of shunt implants, providing insight into optimal shunt design and placement for hydrocephalus patients.
The study explores the technological evolution of surgical robots and their current clinical applications. Surgical robots have addressed challenges in operating within small anatomical spaces, improving medical efficiency, but also increasing costs and complexity of operations.
A novel 3D culture method enables self-organization of precursor cell types into functional liver organoids capable of producing essential clotting factors. The breakthrough advances organoid-based therapies, drug testing, and disease modeling for liver diseases, including hemophilia A.
Recent advances in biofabrication and biomedical electronics have led to the development of biohybrid-engineered tissue (BHET) platforms, turning passive constructs into intelligent systems. These platforms show promise in diverse applications, including brain organoids and cardiac tissues, blurring the line between biology and machine.
A KAIST research team has identified a new molecular mechanism in which alcohol-damaged liver cells increase reactive oxygen species, leading to cell death and inflammatory responses. They discovered that Kupffer cells act as a 'dual-function regulator' that can either promote or suppress inflammation through interactions with liver ce...
Researchers aim to understand the role of blood vessels in traumatic brain injuries and their link to age-related cognitive impairment. They plan to use mice with a mutation in the UCH protein to explore how blocking this protein affects brain sugar processing and neurovascular function.
Researchers at Kyoto University have created a microphysiological system capable of simulating different regions of human lungs, including the airway and alveoli. This breakthrough enables accurate modeling of viral pathologies and holds promise for personalized treatment of respiratory diseases such as COVID-19.
Scientists have discovered that microglia play a crucial role in regulating blood flow to the brain, and targeting them may improve blood flow deficits. The study suggests that restoring microglia function could prevent or reverse memory-stealing diseases caused by lack of adequate blood flow.
A new deep learning model enhances handheld 3D medical imaging by automatically tracking transducer motion without external sensors. The model produces more realistic 3D US images and can reconstruct blood vessel structures using ultrasound and photoacoustic data.
Researchers at RCSI University of Medicine and Health Sciences have developed a 3-D printed implant that delivers electrical stimulation to injured areas of the spinal cord, enhancing nerve cell growth. The study has shown promising results in lab experiments and may enable new medical devices for traumatic spinal cord injuries.
Researchers at Texas A&M University have developed a new type of adhesive that could improve the comfort and safety of wearable medical devices. The adhesive, made from polyelectrolyte-complex coatings, is water-based and has been shown to match the strength of commercial-grade adhesives while reducing skin irritation.
Researchers have developed a 3D bio-printed model of lung tissue that closely mimics natural complexity, enabling better testing of respiratory diseases and drug development. The model can be adapted to include additional cell types or patient-derived cells, making it a powerful tool for personalized medicine and disease modeling.
Scientists at the Stowers Institute for Medical Research identified two distinct genes that regulate regeneration of sensory cells in zebrafish. The discovery may guide future studies on hearing loss and regenerative medicine in mammals, including humans.
Researchers developed a new imaging approach combining two-photon microscopy and advanced algorithms to improve resolution and reduce noise. This allowed them to clearly see details smaller than 250 nanometers, enabling real-time observations of mitochondrial behavior in live animals.
Researchers have engineered a monoclonal antibody that blocks allergic reactions against common pollen when applied inside the nose of mice, providing new hope for hay fever sufferers. The treatment, known as a 'molecular shield,' acts immediately and locally at the lining of the nose to prevent IgE antibodies from being activated.
The new agreement provides unlimited opportunities for open access publishing in JMIR's journals, eliminating article processing charges and streamlining the publication process. This partnership underscores TU/e's commitment to advancing open science and increasing research impact.
Researchers at MIT developed an implantable device that can store glucagon to counteract hypoglycemia, a life-threatening condition for people with Type 1 diabetes. The device, about the size of a quarter, contains a small reservoir made of 3D-printed polymer and can be triggered remotely or automatically by a sensor.
Researchers found that human stem cells can differentiate into bone cells simply by being squeezed through narrow spaces. This discovery could lead to the development of simpler and safer regenerative therapies by using physical signals instead of chemical cues. The study's findings have broader implications, including potential applic...
A new technology combines the coffee-ring effect with plasmonics and AI for rapid diagnostics, offering highly accurate results in under 12 minutes. The test can spot diseases like COVID-19, prostate cancer, and sepsis, making it a game-changer for point-of-care diagnostics.
GeniPhys has received FDA clearance for its self-assembling collagen scaffold, Collymer Self-Assembling Scaffold (SAS), which supports cellular infiltration and vascularization. The technology is indicated for various wound types and anchors a growing intellectual property portfolio with nearly 20 issued or pending patents.