Articles tagged with Biomedical Engineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
JMIR Publications' portfolio of journals now includes 21 titles with a Journal Impact Factor. Several journals saw significant increases in impact factor, including JMIR Medical Education, which debuted with a score of 12.5, securing the top-ranked journal spot in its category.
Researchers found that intercellular flow plays a major role in tissue response to deformation, affecting organs' adaptability to conditions like aging and cancer. The study's findings could inform the design of artificial tissues and organs.
A Waseda University research team developed a method to measure thermal insulation of bedding systems, considering individual body parts. The study found that relying solely on whole-body insulation is not enough and revealed the importance of optimizing sleep environments for better quality.
A new national guideline provides unified strategies for managing RSV infections in children under five, emphasizing rapid antigen detection, oxygen therapy, and pharmacological treatments. The guideline also supports the use of monoclonal antibodies and recommends non-pharmaceutical interventions to prevent pediatric RSV infections.
Researchers at the University of Malaga have identified factors involved in the propagation of toxic protein aggregates, which accumulate in patients' brains. These brain accumulations are formed as a consequence of abnormal folding of soluble proteins and can lead to the spread of disease to different brain regions.
The Fraunhofer Institute's miniaturized quantum magnetometer provides precise measurements of magnetic fields with minimal interference. This technology enables new possibilities in biochemical measurements, microelectronics, and navigation systems, including GNSS-safe navigation without GPS.
A team of scientists from Colorado State University and the University of São Paulo have developed a seismological solution to improve the resolution of ultrasound images for lung monitoring. This breakthrough could lead to improved critical care for patients, including continuous lung monitoring at the bedside. The technique uses seis...
A proof-of-concept study shows that chimeric antigen receptors (CARs) can distinguish between tau tangles and various forms of toxic amyloid plaques, two key contributors to Alzheimer's disease pathology. The technology has the potential to deliver therapeutic drugs directly to affected areas of the brain with reduced side effects.
Researchers developed an intelligent biosensing platform based on luminescent nanoparticles and a microfluidic biochip with machine vision algorithm analysis for efficient tumor marker detection. The platform offers high sensitivity, noninvasive sampling, and portable design for early cancer screening and monitoring.
Professor Garry Duffy joins RCSI with a unique combination of institutional knowledge and fresh leadership perspective, focusing on integrating excellence in health sciences education with innovative patient-centred research. He aims to build on the university's heritage by enhancing anatomical education and pioneering research in rege...
Researchers at the Henryk Niewodniczanski Institute of Nuclear Physics have developed wound dressings containing the antibacterial drug metronidazole, which can be released in a controlled manner. The mats are made from electrospun polymer fibers and could potentially be used to treat infections.
Scientists replace toxic additives in hydrogels with D-sorbitol, a safe sugar alternative found in chewing gum, to create bioelectronic devices that are soft, safe, and integrated with natural tissue. The new material has increased biocompatibility and improved electronic performance.
Researchers engineered human spleen into bioreactor capable of curing diabetes and growing functional organs. The spleen's unique structure hosts billions of transplanted cells and provides a nutrient-rich environment for cell growth.
Researchers developed a new method to study mechanical proteins, revealing that disrupting protein titin causes muscle disease. The technique allows for targeted analysis of protein mechanics, paving the way for new therapeutic strategies.
The Berggren Center for Quantum Biology and Medicine will merge quantum technology with biology to transform medicine, driving the development of revolutionary quantum tools and cultivating bilingual scholars. Researchers will translate quantum advances into clinical solutions, enabling new diagnostics and therapies.
Researchers developed self-propelled ferroptosis nanoinducers to enhance cancer therapy by inducing programmed cell death. The nanotherapeutics exhibited enhanced diffusion and deep tumor penetration while maintaining biocompatibility.
Researchers at UH found cells can detect weak electric fields due to active matter in the cell membrane. This discovery could lead to breakthroughs in medical devices, biosensors, and disease therapies.
Researchers used breath analysis to monitor general anesthesia in children, achieving results comparable to blood tests. The method also detected oxidative stress and potential complications, enabling early detection and prevention.
Researchers developed stable MXene-coated contact lenses providing enhanced protection against electromagnetic radiation. The lenses exhibited a rapid temperature rise when exposed to microwave heating, indicating strong EMR absorption and dissipation.
Researchers use MRI and NASA-inspired negative-pressure pants to improve stress tests, revealing hidden heart issues. The technology transforms heart imaging, making it possible to detect real differences in heart performance.
A Virginia Tech professor has received a proof-of-concept grant to further develop a chemical compound that could help promote weight loss by increasing mitochondrial activity. The compound, named BAM15, shows promise in preclinical studies without affecting food intake or muscle mass.
Researchers developed LUCAS, a rapid and portable diagnostic tool that creates stronger and longer-lasting bioluminescence signals, enabling accurate detection of SARS-CoV-2, HIV, HBV, and HCV in patient samples. The tool achieved an average accuracy of over 94% in detecting viruses within 23 minutes.
Dr. Natalie Artzi joins the Wyss Institute as Associate Institute Director, working closely with Don Ingber to shape strategic direction and advance research and translation efforts. She leads a world-class research program focused on developing tissue- and cell-responsive nanostructures for disease tracking and treatment.
Researchers at Virginia Tech's Fralin Biomedical Research Institute developed a peptide therapy called JM2 that targets cancer cells' ability to renew and regrow. The treatment significantly slows tumor growth in animal models and disrupts the maintenance of treatment-resistant cancer cells.
The article discusses recent advancements in pipeline safety technologies, including defect detection, environmental risks monitoring, and structural integrity assessment. The integration of high-grade steel, large-diameter pipelines, and unconventional energy sources has introduced new complexities to pipeline safety.
Researchers developed a metalens-based microscope that achieves both wide field of view and high-resolution imaging in a compact design. The system uses a doublet configuration and annular illumination to overcome traditional metalens limitations, enabling practical applications in biomedical imaging.
Texas A&M University researchers have developed a customizable vessel-chip method that can mimic various blood vessel structures, enabling more accurate models of vascular disease. The chip technology enables patient-specific research and pharmaceutical testing, with the potential to cure vascular diseases.
Researchers at TU Wien have developed a method to create artificial blood vessels using ultrashort laser pulses, enabling the creation of mini organ models with precise control and reproducibility. The technology has been successfully applied to liver tissue models, resulting in improved metabolic activity and adequate nutrient supply.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
The COLD-TUG test measures the time required for prosthetic donning and mobility in lower-limb amputation patients. Researchers found that patients with bone-anchored prostheses can don their prosthesis significantly faster, saving up to 61 seconds per session.
Researchers discovered a DNA switch in TB bacteria that regulates growth and gene expression. By targeting this process, new antibiotics could be developed to make the bacteria easier to eliminate.
Seven Clusters of Excellence at LMU Munich have been approved for funding, covering a broad range of fields from systems neurology to quantum science. The successful clusters reflect the university's exceptional commitment and cooperation with partners.
A Johns Hopkins Medicine study finds that SARS-CoV-2 corrupts white blood cells, specifically neutrophils, to impair the production of immune cells critical for fighting COVID-19. This reprogramming may lead to severe COVID cases by weakening the immune response against the virus.
The new 3D-printed device, STOMP, enhances tissue-engineering methods by allowing for precise control over cell types and spatial arrangement. This enables scientists to model complex diseases and recreate natural habitats of cells, paving the way for advancements in biomedical research.
A joint research team from POSTECH and Hanyang University developed a personalized stimulation control mechanism using evoked compound action potential feedback mechanisms to treat urinary disorders. This technology enables precise adjustment of tibial nerve stimulation in real-time, based on individual nerve responses, improving patie...
Triboelectric and piezoelectric nanogenerators convert mechanical energy into electrical energy, enhancing robotic autonomy and efficiency. The technology has the potential to reshape future robotic capabilities, particularly in industrial automation, healthcare, and smart home applications.
Researchers at Rice University have developed a novel personalized medicine approach for addressing movement impairments. The Neuromusculoskeletal Modeling (NMSM) Pipeline software allows clinicians to work in collaboration to construct personalized computer models of individual patients, leading to more effective orthopedic surgery, p...
A new AI system, MedGaze, is designed to emulate how radiologists visually interpret chest X-rays. By replicating expert attention, it helps train future specialists and improve the efficiency of hospitals through better workflow management.
A study led by Johns Hopkins Medicine found a genetic mutation, F722fs, in the MMS22L gene that is associated with a higher risk of prostate cancer. The researchers identified this mutation in Ashkenazi Jewish men and found it was linked to increased sensitivity to a specific anticancer therapy.
UT Dallas bioengineers have created an enhanced light-activated immunotherapy approach to target advanced stomach cancer. Lab-designed molecules are primed with far-red or near-infrared light to activate the immune system against stubborn cancer cells, reducing side effects.
Researchers at Boston University School of Medicine discovered that PAX3 mainly uses its paired domain to bind to DNA and turn on genes promoting cell growth and survival. The study suggests that targeting the paired domain of PAX3 could be an effective way to treat melanoma.
A new study describes a promising new type of auditory brainstem implant that could benefit people who are deaf due to NF2 and other severe inner ear abnormalities. The soft, flexible implant bypasses damaged auditory structures and directly stimulates the brainstem's sound-processing region.
A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.
Researchers analyzed data from a wearable device to find that women's physical activity levels are less variable and more predictable than men's. The study also found no significant difference in physical activity levels between individuals with and without menstrual cycles.
The University of Utah is partnering with XPRIZE to improve healthy aging through a 7-year, $101 million global competition. The partnership aims to validate the science of competing teams working towards extending health spans for aging populations.
New research from Binghamton University reveals that the topography patterns of wrinkled fingers remain constant after multiple immersions. The study found that blood vessels beneath the skin contract and move in relation to other vessels, resulting in consistent wrinkles.
Researchers from The University of Osaka developed a new technique using mass photometry to detect and quantify components of rAAV particles. This method can distinguish between full and empty particles, streamlining gene therapy manufacturing and improving clinical effectiveness.
Researchers at Brown University developed targeted liposomes that dramatically increased drug effectiveness against fungal infections, even those caused by tough-to-treat biofilms. The approach also appears to be generally safe, showing no toxicity to human cells commonly affected during infection.
A Phase II trial demonstrates the safety and clinical benefit of PRL3-zumab, a novel humanised antibody therapy targeting PRL3 in advanced solid cancers. The treatment has shown promising results, slowing disease progression in patients with no response to existing treatments.
A study found that microRNA-27a promotes dental tissue regeneration by suppressing inflammation and activating Wnt/BMP signaling pathways. The researchers used human dental pulp stem cells to overexpress miRNA-27a, which led to the formation of new bone-like tissue in mice.
Researchers explored combining checkpoint blockade therapy with in situ vaccination to improve anti-tumor immunity in colorectal cancer. This innovative approach aims to mitigate adverse effects and enhance treatment effectiveness by targeting immune checkpoints and promoting tumor-specific T cell responses.
Researchers have discovered terahertz light waves can reduce hyperactivity in brain regions associated with depression, leading to rapid improvements in mood and thinking ability. The treatment works without introducing foreign substances into the brain and is safe for use at therapeutic intensities.
The journal is inviting submissions on AI applications in biomedical engineering, focusing on medical device development, personalized diagnostics, and patient outcome prediction. Accepted articles will be published as part of a themed section showcasing current research on AI applications in biomedical engineering.
Scientists develop brain-computer interface that allows users to design distinct tactile experiences for different objects, enabling them to guess the object by sensation alone. The study represents an important step towards creating a neuroprosthetic that feels pleasant and intuitive to use.
A recent study found that fine-tuned GPT-4 chatbot can provide trustworthy information to pregnant women with opioid use disorder. The chatbot uses motivational interviewing and evidence-based guidelines to help individuals overcome resistance to change and access local treatment centers.
Researchers have identified Clusterin as a novel marker capable of functionally categorizing aged HSCs. Clu-positive HSCs showed an increased propensity towards differentiating into platelets or myeloid cells, while Clu-negative HSCs maintained a balanced cell production approach typical of younger stages.
The Virginia Tech Helmet Lab has released an updated set of equestrian ratings that considers impact scenarios with horizontal velocity, typically occurring in racing and cross-country events. The new ratings aim to inform consumer decisions about helmet purchasing by reflecting concussion risk associated with each model.
A new brain-inspired algorithm developed at BU can help hearing aids tune out interference and isolate single talkers in a crowd of voices. In testing, researchers found it could improve word recognition accuracy by 40 percentage points relative to current hearing aid algorithms.
Researchers developed a brain decoder to restore communication between the brain and spinal cord, allowing for rehabilitation and potentially restoring movement. The decoder used electroencephalography to predict movement intention, outperforming previous methods.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.