Articles tagged with Biomedical Engineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed a new approach to engineer tissue structures across multiple scales, from small cells to large organs. They used gallium as a molding material, allowing them to create complex vascular and interwoven networks that mimic natural biological systems.
Researchers at TUM have grown tumor organoids that reproduce the morphological complexity of pancreatic cancer cells in the laboratory. The team used machine learning to categorize the organoids into different phenotypes based on their appearance and behavior, which react differently to treatments.
Silvia Blemker, a University of Virginia biomedical engineer, has been elected Fellow of the National Academy of Inventors (NAI) for her work on muscle health. Her patented technology, Image-based Identification of Muscle Abnormalities, uses advanced imaging and analytics to provide detailed insights into muscle health.
A team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia by mapping what happens in different brain regions during that moment. The study found that rapid activity in the medial prefrontal cortex, hippocampus, and thalamus triggers loss of consciousness.
The InteReg project aims to create interactive biomaterials that instruct cells to regenerate after brain or spinal cord injuries, potentially treating MS and other neurological disorders. The project, funded by the Carl Zeiss Foundation, brings together experts in biology, chemistry, medicine, and polymer research.
Researchers at Harvard University have developed a tissue-anchoring mechanism for medical devices, inspired by the circular hook-like attachment organ found in intestinal tapeworms. The device can be deployed in under 1 millisecond and anchors into soft tissue with minimal damage.
Researchers develop innovative hybrid control strategy to improve product yields in biosynthetic processes. The new approach combines model-based optimization with in-cell feedback control, outperforming traditional methods and promising reduced costs and environmental impact.
Researchers developed a microfluidic chip that can measure memory B cells' binding affinity to flu virus, helping track immunity. The device, Shear Activated Cell Sorting (SACS), can compare how well cells bind to original and new variants.
Researchers from Universitat Jaume I developed a non-invasive device for female urination in bedridden women, addressing comfort and sealing issues. The ERGOMIC device uses the Coanda effect to efficiently direct urine flow, making it simple, cheap, and reusable.
Researchers develop ultrasound-based method to control cell growth and orientation in cultured muscle cells. The technique uses ultrasonication to promote differentiation of myoblasts into myotubes, offering a promising alternative to current methods.
A team of researchers at Penn State developed a novel bioprinting technique that uses spheroids to create complex tissue, producing tissue 10-times faster and with high cell density. The technique enables the rapid fabrication of functional tissues and organs, opening new opportunities for regenerative medicine.
Researchers assess 20 years of clinical trials for cell therapy's safety and efficacy in treating heart failure, highlighting progress despite challenges. The field continues to evolve through lessons learned from past studies, with ongoing trials taking novel directions.
Dr Bøsch's work explores betalains' potential to impact blood pressure, diabetes, cardiovascular health, and gut microbiota. The award highlights the significance of her research in advancing functional food and feed applications with implications for human and animal health.
Researchers at UVA have developed a new polymer design that decouples stiffness and stretchability, allowing materials to be both strong and flexible. The 'foldable bottlebrush polymer networks' can store extra length within their structure, enabling them to elongate up to 40 times more than standard polymers without weakening.
Researchers at the University of Illinois have created a DNA-made nanorobot called NanoGripper that can pick up COVID-19 viruses for rapid detection and block viral particles from entering cells. The device also has potential applications in cancer treatment and preventive medicine.
The Emory University Hospital team successfully implanted the BrioVAD System, a novel magnetically levitated pump designed for patient ease and long-term health. This marks the first-time use of the device in the US, as part of the INNOVATE clinical trial.
Researchers created an animal model with a targeted mtDNA mutation to advance understanding of mitochondrial genetic disorders. The study found significant changes in brain structure and function, as well as metabolic abnormalities, linking mitochondrial dysfunction to cognitive-metabolic impairments.
Researchers have developed a new method for designing large artificial proteins with high accuracy, utilizing AI-based software Alphafold2. The approach combines accurate structure prediction with optimization techniques, allowing for the creation of proteins with tailored properties, such as precise binding and stability.
A team of researchers at the University of California San Diego has developed a clinically validated, wearable ultrasound patch for continuous and noninvasive blood pressure monitoring. The device offers precise, real-time readings of blood pressure deep within the body, providing detailed trends in blood pressure fluctuations.
GNOMX Corp. has been awarded a contract by the US Department of Health and Human Services to develop an immune dysregulation host-based assay to predict sepsis patient readmission risk. The assay aims to reduce hospital expenses and improve patient outcomes.
The joint Ph.D. program will combine engineering immersion, commercialization training, and clinical shadowing to produce medical innovators capable of addressing unmet clinical needs. Students will be trained in translational thinking, engineering design principles, and entrepreneurship to develop technologies for precision diagnostic...
Christian Wolfrum will serve as NTU's chief academic officer, overseeing educational and research excellence, while strengthening talent development. He brings experience in translating research into real-world applications, having co-founded biotechnology firm Glycemicon AG.
Researchers at UVA discovered the heart reacts to viral infections in one of three ways, with specific gene patterns indicating healing or damage. This finding may lead to better treatments for people at risk of heart failure and other chronic conditions linked to viral infections.
A new CNIC study identifies a surprising mechanism through which tissue viscoelasticity counteracts the sensing of rigidity. Cells respond to ECM viscoelasticity regulating response times and outweighing high-rigidity sensing.
Researchers developed a new AI-powered diagnostic system, FastGlioma, which reveals invisible cancerous tissue in brain tumor surgery. The technique may delay or prevent recurrence of high-grade tumors and improve patient survival.
Team Bath Heart, a team of students from the University of Bath, has won the second world Heart Hackathon title with their innovative artificial heart device. The team's prototype, which uses wireless charging and 3D printing, was praised for its novelty, progress, and presentation.
The study reveals that the hadal snailfish has unique metabolic adjustments to store energy, optimize energy utilization, and maintain membrane fluidity. The fish increases lipid reserves, elevates CoQ and ATPase levels, and adjusts fatty acid ratios to withstand food scarcity and high pressure.
Researchers have developed a new CRISPR-Cas method to decipher the function of genetic variants that contribute to cancer. The approach creates tens of thousands of cells with different gene variants, allowing scientists to identify which variants make cancer cells resistant to standard drugs.
Researchers at the University of British Columbia have developed a groundbreaking coating that mimics natural blood vessels to reduce clotting and bleeding risks. The coating's unique properties prevent clot formation without disrupting normal blood functions, offering a promising alternative to high-risk blood thinners.
Adipo Therapeutics' lead product ADPO-002NP shows promising results in increasing energy expenditure and improving insulin resistance by browning white adipose tissue. The company is now raising $8 million to move the treatment to first-in-human Phase I clinical trials.
Researchers led by Judith Su will develop a portable FLOWER sensing device for detecting zeptomolar concentrations of chemical warfare agents. The device has shown record-breaking sensitivity and could preserve the lives of active-duty service members.
A team of researchers, including Binghamton University's Ahyeon Koh, is working on an innovative project to treat inflammatory bowel diseases like Crohn's and ulcerative colitis. The goal is to create a 'cell factory' in the body that can produce pharmaceuticals to alleviate symptoms.
Researchers developed a new AI model, BiomedGPT, to support various biomedical tasks. The model achieved 16 state-of-the-art results in 9 biomedical tasks and demonstrated robust predictive abilities.
Researchers developed a wearable ultrasound device that tracks muscle function without invasive procedures, offering high-resolution imaging and wireless monitoring capabilities. The technology has potential applications in respiratory health and human-machine interfaces.
Researchers have developed a new batteryless and wireless sensor that can detect impending biliary stent obstructions without waiting for clinical symptoms, blood tests or imaging tests. The sensor is 8 millimeters long and has a signal-to-noise ratio of a million to one during testing.
The US Department of Defense has awarded $514,000 to study the efficacy of gene editors in treating Duchenne Muscular Dystrophy. Researchers will explore non-viral options for delivering gene therapy through 'self-delivering' gene editors, aiming to improve safety and efficacy.
Researchers at the University of Rochester developed a new liquid biopsy method called CAD-LB, which uses ultrathin membranes to easily identify EVs for rapid diagnosis. The method holds promise for diagnosing cancer quickly and affordably, as well as assessing therapy progress.
Researchers have made breakthrough in developing artificial kidney tissue from scratch, which could reduce the need for dialysis and transplantation. The study discovered a potential governor of kidney growth, tiny mechanical stress waves, to understand how nature builds the organ.
Researchers at Osaka Metropolitan University have found that plasma irradiation can enhance tendon-to-bone junction repair, leading to faster healing rates and stronger repairs. The study used rabbit models to test the effects of plasma on rotator cuff injuries, showing promising results.
Researchers at the University of Oxford have developed a miniature, soft lithium-ion battery with features like high capacity, biocompatibility, and biodegradability. The battery was used to power small devices in animal models and demonstrated promising results for wireless and biodegradable devices in clinical medicine.
A new hydrogel semiconductor has been developed by the UChicago Pritzker School of Molecular Engineering, enabling better brain-machine interfaces, biosensors, and pacemakers. The material's soft mechanical properties and high charge-carrier mobility make it ideal for tissue-level interfaces.
Researchers at the University of Chicago and UC San Diego have developed a cutting-edge bioelectronic device that harnesses the natural electrical activity of certain bacteria to manage infections. The device achieves remarkable results by delivering gentle electrical signals, reducing bacterial colonization nearly tenfold.
A new study in mice shows a unique mRNA delivery method can successfully edit faulty genes in fetal brain cells. The technology has the potential to stop progression of genetic-based neurodevelopmental conditions like Angelman syndrome and Rett syndrome before birth.
GeniPhys secures $500k NSF grant to support regulatory and commercial readiness of Collymer SAS for soft tissue restoration in advanced wound care. The technology promotes regenerative remodeling without inflammatory response, facilitating faster healing and tissue repair.
The ASHG 2024 Annual Meeting will showcase the latest research in human genetics and genomics. The event will feature a Presidential Symposium on Mendelian traits and a Distinguished Speakers Symposium on the promise of human genetics and genomics, among other sessions.
Researchers aim to improve gene therapy design for life-long correction of genetic diseases, but face unknowns including immune response and genomic changes. A five-year NIH award will fund an analysis of genetic and cellular determinants of gene therapy longevity.
Researchers are creating microphysiological systems to simulate infection and treatment in vitro, linking human lung and brain tissue models. This project aims to explore the relationship between respiratory diseases and neurological symptoms, potentially leading to new treatments.
A groundbreaking study has demonstrated the clinical success of a new nanoparticle-based, laser-guided therapy for prostate cancer treatment. The therapy successfully eliminated cancerous cells in 73% of patients after 12 months while preserving key functions and side effects.
The National Institutes of Health has announced the winners of the RADx Tech for Maternal Health Challenge, an $8 million prize competition to develop innovative diagnostics for postpartum maternal health. Six finalists won grand prizes of $525,000 each, and two runner-up teams won prizes of $300,000 each.
A UMass Amherst-led team has developed a sensor to detect sodium ions in breastmilk, a biomarker of elevated mammary permeability and potential milk supply issues. The device provides highly sensitive readings inexpensively and quickly, with results delivered in three minutes and costs just $1 per test.
Biomedical engineer Jeff Saucerman has received a $3.1 million NIH grant to study low-density lipoprotein receptor 1 and its impact on heart failure and treatment outcomes after a heart attack.
Researchers have developed a cell culture platform to form two distinct, interconnected vascular networks, replicating human physiology and reducing animal testing costs. This breakthrough enables the study of cellular interactions in vascularized tissues.
Scientists create synthetic biology approach to mechanistically study tissue patterning and engineer organoid structures by combining morphogens with cell adhesion control. The model system reveals a key feature of E-cadherin for forming sharp boundaries in synthetic tissue domains.
Researchers developed a microchip that captures exosomes from blood plasma to identify signs of lung cancer, achieving 10x faster detection and 14x greater sensitivity. The chip uses twisted gold nanoparticles to distinguish between healthy patients and those with lung cancer.
A Carnegie Mellon-led team has secured a $42 million grant to develop implantable, cell-based bioelectronic devices for real-time therapy and disease monitoring in patients with thyroid disorders. The devices will offer adjustable, low-cost treatment and continuous biomarker measurement.
A Carnegie Mellon University-led team is developing a bioelectronic implant called ROGUE that can produce a year's supply of treatment for chronic diseases like Type 2 diabetes and obesity. The device will offer continuous, adjustable therapy deployment via a minimally invasive procedure.
A team of engineers and scientists from Caltech has developed a headset-based device that can noninvasively assess a patient's stroke risk by monitoring changes in blood flow and volume. The device uses speckle contrast optical spectroscopy to differentiate between individuals at low and high risk of stroke.
A new hand-held scanner can generate highly detailed 3D images in seconds, paving the way for earlier disease diagnosis. The technology uses laser-generated ultrasound waves to visualize subtle changes in blood vessels, helping inform patient care and diagnose conditions like cancer and cardiovascular disease.
Recent engineering efforts develop various sensors and devices for addressing challenges in personalized pain treatment. These intelligent sensors and devices offer real-time, accurate pain assessment and responsive treatment options.
A team from the University of Michigan School of Dentistry has patented a new regenerative bone graft material that can regenerate about eight times more bone than existing scaffolds. The breakthrough could transform bone grafts for millions of people who require them, reducing costs and complications associated with traditional methods.