Articles tagged with Biomedical Engineering
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A team of researchers has created artificial small-diameter vessels (SDVs) featuring pores that enable the formation of an endothelium without additional processing steps. The 3D-printed vessels were successfully infused with human cells, demonstrating spontaneous cellular assembly and paving the way for potential transplantation and f...
Scientists have developed a new biocompatible material that can conduct electricity efficiently in wet environments and interact with biological media. The modified PEDOT:PSS enables the creation of organic electrochemical transistors (OECTs) with high performance and excellent characteristics.
Researchers at The University of Tokyo developed a bio-tagging method using dissolvable microneedle arrays for permanent animal identification. The approach, called 'MAPs,' uses customizable molds to tattoo unique identifiers into the skin, offering a safer and more humane alternative to traditional ear tags or RFID chips.
Researchers at UMass Amherst have received an NIH grant to create predictive models for Alzheimer's disease using brain MRIs and clinical data. The goal is to enable earlier detection of the condition, ideally two years before onset of symptoms.
Researchers develop injectable hydrogel electrodes for treating ventricular arrhythmia, providing a potential solution to painful defibrillation and improving quality of life. The novel pacing modality addresses the pathophysiology of re-entrant arrhythmia and offers a promising alternative to existing therapies.
The University of Rochester is establishing a new NIH-funded center focused on developing FDA-qualified drug development tools related to barrier functions in disease. Researchers will create microphysiological systems with ultrathin membranes of human cells, aiming to reduce animal trials and improve drug efficacy.
Researchers found that specific microbes in the gut reduce graft versus host disease after stem cell transplantation. Patients with low microbial metabolite risk index had better survival rates, fewer graft vs. host reactions, and reduced relapses.
Researchers developed a novel test that detects single ⍺-synuclein fibrils in patient samples to identify patients with Parkinson's disease earlier. This breakthrough has the potential to create early applicable molecular diagnostics, improve clinical trials, and facilitate drug screening for neurodegenerative diseases.
Researchers developed mathematical models based on real events data from the Swedish Trauma Registry, showing that AI models outperformed clinical outcomes. The study highlights the potential of AI-powered decision support to improve ambulance staff's ability to assess injury severity and potentially save more lives.
A Texas A&M University-led collaboration has developed new polymers capable of killing bacteria without inducing antibiotic resistance by disrupting their membrane. The researchers tested their polymers against two main types of antibiotic-resistant bacteria, including E. coli and Staphylococcus aureus (MRSA), with promising results.
A research group reconstituted autophagosome formation in vitro, showing that Atg8 protein and enzymes play a central role in shaping the membrane structure. High-speed atomic force microscopy and nuclear magnetic resonance analysis revealed flexible complexes on membranes, which work together to form autophagosomes.
Researchers at KIT have developed a method that uses radiation more efficiently to produce images of micrometer resolution, allowing for longer observation times of small living organisms. The method combines X-ray phase contrast with a Bragg magnifier and photon-counting detector.
Researchers have developed a spinal cord stimulation technology that restores sensation, improves function, and reduces phantom limb pain after trans-tibial amputation. The study showed significant improvements in balance control and gait stability, with an average 70% reduction in phantom limb pain.
Researchers developed a non-invasive MRI technology to measure interstitial fluid flow, crucial for tumour treatment. The new method combines phase-contrast MRI with an improved stimulation echo sequence, reducing signal loss and improving detection accuracy.
Researchers from SFU and UBC introduce MCS-DETECT, an AI-driven algorithm that detects membrane contact sites in large microscopy volumes without segmentation. This innovation enhances super-resolution microscopy capabilities, contributing to a better understanding of cellular interactions and complex diseases.
The new robotic replica, called RRV, can mimic healthy and diseased states, allowing scientists to test cardiac devices and therapies. The model can also be used to study the effects of mechanical ventilation on the right ventricle and develop strategies to prevent right heart failure.
A new study on wearable health monitors reveals that a failure to understand race leads to flawed technology, exacerbating existing racial health inequities. The researchers found significant challenges with 'race correction' in health technologies, which assumes biology over system racism.
A team of engineers has developed a novel printing method called deep-penetrating acoustic volumetric printing (DVAP) that uses soundwaves to solidify biologically compatible structures in deep tissues. The technique involves a specialized ink that reacts to ultrasound waves, enabling the creation of intricate structures for biomedical...
Researchers at the University of Arizona developed a low-power wide area network (LPWAN) system that enables wearables to transmit health data long distances without cell coverage. The system, called biosymbiotic, has the potential to improve remote monitoring in underserved communities and make digital medicine more accessible
Scientists at University of Toronto and Sinai Health created transplants with genetic modification, persisting long-term in mice without immune suppression. This breakthrough may transform cell therapies for incurable diseases, making transplantation safer and more widely available.
Researchers developed a lightweight wearable balance exercise device to improve reactive postural control in older adults, reducing the risk of falls. The device uses pneumatic artificial muscles to generate unexpected perturbations, resulting in improved peak displacement and velocity.
A new study by the University of Plymouth reveals that chlorine disinfectants used in hospitals are no more effective at killing off hospital superbugs than water. The research highlights the need for alternative strategies to tackle Clostridioides difficile, which causes diarrhoea, colitis and other bowel complications globally.
Researchers have developed additively manufactured Ti-Ta-Cu alloys that exhibit improved biocompatibility and bacterial resistance, making them a promising alternative to traditional Ti6Al4V implants. The alloys were found to display remarkable synergistic effects in improving both in vivo biocompatibility and microbial resistance.
Researchers developed a new bispecific antibody therapy to target myeloma cells with drug resistance. The therapy, called B-BiTE, successfully activated human T cells and NK cells against various myeloma cells.
A new technology enables the printing of complex robots with soft, elastic, and rigid materials in one go. This allows for the creation of delicate structures and parts with cavities as desired.
The POLINA project will develop new materials and technologies for medical applications, aiming to revolutionize bioprinting for safer, smarter and affordable medical devices. The project will create micropatterned cell surface models to help study lung diseases and design new tracheal implants.
A novel robotic system developed by USC researchers can help clinicians accurately assess a patient's rehabilitation progress. The method generates an 'arm nonuse' metric using machine learning and a socially assistive robot to track how much a patient is using their weaker arm spontaneously.
Researchers developed a handheld, wireless biosensor to detect Alzheimer's and Parkinson's biomarkers from saliva and urine samples. The device has shown high accuracy comparable to existing state-of-the-art methods.
A team led by WPI researcher Ulkuhan Guler has received NIH funding to develop a wearable sensor for premature infants that can mitigate skin-color bias in oxygen level measurements. The four-year project aims to create a convenient and affordable sensor that will enable infants at risk of lung disease to leave hospitals sooner.
A study tracked skin temperature in 600 participants for six months, finding that individual differences were more significant than sex-based variations. The team used wearable devices to monitor skin temperature and found patterns consistent with menstrual cycles in women.
A new URI lab is developing an adaptive robotic platform to help post-stroke patients regain motor skills and perform daily tasks. The device incorporates user feedback and monitoring of muscle and brain activity to tailor its approach.
A team of researchers developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in vertebrate embryonic development. The study uses zebrafish to investigate how Vg1 is formed and found that it must undergo additional processing before it can be activated.
The Southwest-Midwest Pediatric Device Innovation Consortium has supported over 200 pediatric device innovators and companies, developing several devices in the past five years. The consortium's portfolio includes real-world evidence research projects using digital tools for collecting and analyzing patient data.
Researchers from Incheon National University create gelatin patches that generate molecular oxygen to accelerate wound healing. The new hydrogels demonstrate improved coagulation, blood closure, and neovascularization in both in vitro and in vivo experiments.
A recent study analyzing global and national trends of atherosclerosis found an increasing trend in incidence from 1990 to 2019, driven by adults aged 20–54. The burden of the disease is particularly concerning in low- and middle-income countries, where it is rising significantly due to lifestyle factors and aging populations.
Researchers at Osaka Metropolitan University have developed a new simulation method using AI to predict powder mixing with high accuracy and low computational costs. This breakthrough enables large-scale and long-duration powder mixing processes, set to enhance product quality and streamline production.
Scientists from Central South University develop a novel approach to address bacterial infection in bone transplantation by enriching H2O2 and amplifying the Fenton reaction. The technique enhances biocompatibility and safety, promising reduced transplant failures and post-operative complications.
The Center for Advancing Point of Care Technologies (CAPCaT) has received a five-year, $8.9 million award from the NIH to develop innovative point-of-care health technologies. The program aims to address heart, lung, blood and sleep disorders in underserved populations.
Researchers used dynamic total-body PET scans to visualize immune T cell distribution in recovering patients. The study found increased concentrations of CD8+ T cells in the bone marrow of recovering COVID patients compared to healthy controls.
Jinglei Ping, a UMass Amherst engineering professor, has received a $1.9 million grant to investigate a new method of regulating exosome traffic using electronic signals. This approach aims to control cell communication in cancer and heart disease research.
Researchers developed robotic prosthetic ankles controlled by nerve impulses, allowing amputees to move more naturally and improving stability. The study found that users were significantly more stable when using the robotic prototype, changing their postural control strategy and mimicking the body's behavior.
Researchers developed a human in vitro model of radiation-induced lung injury, closely mimicking the complexities of the disease. The Human Lung Alveolus Chip recapitulates hallmarks of RILI, including DNA damage, inflammation, and injury to lung cells and blood vessels.
Researchers have discovered new insights into microglia-astrocyte communication and its impact on intracerebral hemorrhage, as well as the testicular toxicity of triptolide. Additionally, a study on epicardial cells has identified key gene markers associated with cardiac regenerative therapy strategies.
A new simulation paradigm for cortical prosthetic vision has been developed, enabling more realistic brain surface mapping and improving 'bionic eye' outcomes. Researchers used MRI-derived phosphene maps and clustering algorithms to determine optimal electrode implantation sites.
The STARTUP Central project empowers public university researchers to commercialize their biomedical innovations. A smart online educational curriculum, InspireU2 iTi, will train academics on product development, business structuring, and more. The program aims to bridge the gap between groundbreaking discoveries and real-world solutions.
A new method was developed to predict organ motion in cancer patients undergoing radiation therapy, utilizing cross-sectional images from three orientations. The results showed improved accuracy when analyzing all three directions, with errors reduced to as low as 2.13mm.
Researchers at Wake Forest Institute for Regenerative Medicine successfully created full thickness human bioprinted skin, promoting quicker healing and more naturally appearing outcomes. The bioprinted skin facilitated human-like skin architecture in vivo, with improved wound closure, reduced scarring, and enhanced tissue formation.
Researchers at the University of Massachusetts Amherst have developed a new method for DNA detection that is 100 times more sensitive than traditional methods. This breakthrough enables fast and accurate disease diagnosis, reducing wait times for lab processing from days to minutes.
Researchers at Northwestern University developed Lattice, a device that simulates human disease in multiple organs to analyze interactions and test new drugs. The technology can replicate complex disease processes, allowing scientists to study the effects of obesity on endometrial cancer, for example.
Researchers created a tiny 3D cell culture model that mimics the function of lymphatic vessels to explore how inflammatory substances affect the lymphatic system. They found that certain cytokines cause cells to tighten their junctions, leading to reduced fluid drainage and swelling. Inhibiting a protein called ROCK2 reversed lymphedem...
Researchers have developed DeepMB, a neural network that reconstructs high-quality optoacoustic images about 1,000 times faster than state-of-the-art algorithms. This enables clinicians to access optimal MSOT image quality in real-time, positively impacting clinical studies and patient care.
Researchers at UVA Health System have developed a powerful new tool to understand how medications affect men and women differently. The model has provided unprecedented insights into biological processes in the liver, helping ensure that new medications will not cause harmful side effects.
Researchers have found that neural activity in the brain changes between sensing a stimulus and taking action, regardless of the context. This discovery has implications for understanding executive functions and potentially aiding in the development of autonomous vehicle systems.
A novel adhesive, engineered from protein coacervates, exhibits robust adhesion and real-time skin healing properties. The adhesive surpasses existing adhesives in sheared adhesion strength and promotes cell proliferation and migration, enabling in situ skin regeneration.
Researchers at the University of California - San Diego developed screen-printed, flexible sensors that can record brain activity and lactate levels in earbuds. The sensors allow for long-term health monitoring and detection of neuro-degenerative conditions.
Five lung stem cell variants dominate CF lungs, causing inflammation, fibrosis, and mucin secretion. CFTR modulators fail to suppress these inflammatory variants, suggesting they as key targets for new drugs.
A new biomimetic chip has been developed to simulate the human gastric mucosa, combining organoid and organ-on-a-chip technologies. The biochip replicates mechanical stimulation and cell-to-cell interactions, mimicking key features of the human stomach's defense mechanisms.
A Rice University-led team of researchers has been awarded $45 million to develop a new sense-and-respond implant technology that could improve immunotherapy outcomes for patients with difficult-to-treat cancers. The technology, called THOR, aims to provide real-time data from the tumor environment to guide more effective therapies.
A recent study published in Journal of Advertising sheds light on the effects of in-stream video advertising on ad information encoding. The research found that mid-roll ads elicit negative emotions but do not affect viewers' purchase intention. In contrast, pre- and post-roll ads have a significant impact on memory formation, highligh...
Researchers develop novel measurement technique to analyze desorption of molecules from microbubbles under ultrasound irradiation. The study reveals that significant amounts of adsorbed molecules are released into surrounding media, and the process depends on bubble size.