Articles tagged with Biomedical Engineering
Researchers have developed a technique to grow stem cells into single sheets, increasing the secretion of signaling proteins that help repair tissue and regulate the immune system. This new approach could improve stem cell-based treatments for conditions such as heart disease, liver damage, and autoimmune illnesses.
Researchers developed an in-silico meta-analysis tool to determine optimal laser irradiation conditions for treating nevus of Ota. The study found that picosecond laser treatment demonstrated higher efficacy and equivalent safety compared to nanosecond laser treatment.
Researchers at the Wyss Institute have identified vorinostat as a promising treatment for Rett Syndrome using an AI-driven drug discovery process and innovative disease modeling. The findings demonstrate disease-modifying abilities across multiple tissues, offering hope for a potentially curative treatment.
Scientists have developed a miniature device that mimics human bone marrow and immune environment, enabling predictive testing of cancer immunotherapy success in patients. The device recreates three regions of bone marrow where leukemia develops and retains the complex immune environment of the tissue.
Researchers have successfully controlled a dexterous robotic hand using noninvasive EEG-based Brain-Computer Interfaces (BCIs) for individual finger movements. The study demonstrates real-time brain decoding and motor imagery control, paving the way for potential applications beyond basic communication to intricate motor control.
Researchers developed patient-specific Cancer Chips to model esophageal tumor microenvironments, enabling accurate prediction of chemotherapy responses. The approach can rapidly stratify patients into responders and non-responders, paving the way for personalized medicine.
Researchers found increased activity in two brain areas when participants reported cognitive fatigue: the right insula and dorsal lateral prefrontal cortex. These areas work together to regulate mental effort, suggesting that external incentives can prompt increased cognitive effort.
UVA Health received two anonymous $25 million estate gifts to support the Paul and Diane Manning Institute of Biotechnology. The institute will develop new treatments for hard-to-treat diseases with a state-of-the-art biomedical research facility expected to drive economic growth in Central Virginia.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
The new centre will investigate neural dynamics, developing novel interventions and devices to improve symptom relief and quality of life for people with brain disorders. It aims to harness neural dynamics for people with conditions like Parkinson’s disease or epilepsy.
Researchers from Binghamton University confirm the long-held 'urban myth' that saltwater dries out skin, increasing tissue stiffness and stress. A simple solution to alleviate tightness is taking a shower after coming out of the ocean.
Researchers at UC Irvine have successfully tested a new replacement heart valve designed for toddlers and young children with congenital cardiac defects. The Iris Valve can be implanted via a minimally invasive catheter, allowing treatment to begin earlier in very young patients.
Scientists from Institute of Science Tokyo create photo-switchable binding of DNA nanostructures that generate two distinct directional motions. The research paves the way for innovative fluid-based diagnostic chips and molecular computers.
Scientists have created a novel method to distinguish between healthy and senescent cells using electric fields, marking a fresh start in ageing research. The frequency-modulated dielectrophoresis (FM-DEP) technique is label-free, rapid, and easy to apply, allowing for the characterization of cell type by measuring the cutoff frequency.
A new national guideline provides unified strategies for managing RSV infections in children under five, emphasizing rapid antigen detection, oxygen therapy, and pharmacological treatments. The guideline also supports the use of monoclonal antibodies and recommends non-pharmaceutical interventions to prevent pediatric RSV infections.
JMIR Publications' portfolio of journals now includes 21 titles with a Journal Impact Factor. Several journals saw significant increases in impact factor, including JMIR Medical Education, which debuted with a score of 12.5, securing the top-ranked journal spot in its category.
Researchers found that intercellular flow plays a major role in tissue response to deformation, affecting organs' adaptability to conditions like aging and cancer. The study's findings could inform the design of artificial tissues and organs.
A Waseda University research team developed a method to measure thermal insulation of bedding systems, considering individual body parts. The study found that relying solely on whole-body insulation is not enough and revealed the importance of optimizing sleep environments for better quality.
Researchers at the University of Malaga have identified factors involved in the propagation of toxic protein aggregates, which accumulate in patients' brains. These brain accumulations are formed as a consequence of abnormal folding of soluble proteins and can lead to the spread of disease to different brain regions.
The Fraunhofer Institute's miniaturized quantum magnetometer provides precise measurements of magnetic fields with minimal interference. This technology enables new possibilities in biochemical measurements, microelectronics, and navigation systems, including GNSS-safe navigation without GPS.
A team of scientists from Colorado State University and the University of São Paulo have developed a seismological solution to improve the resolution of ultrasound images for lung monitoring. This breakthrough could lead to improved critical care for patients, including continuous lung monitoring at the bedside. The technique uses seis...
A proof-of-concept study shows that chimeric antigen receptors (CARs) can distinguish between tau tangles and various forms of toxic amyloid plaques, two key contributors to Alzheimer's disease pathology. The technology has the potential to deliver therapeutic drugs directly to affected areas of the brain with reduced side effects.
Researchers developed an intelligent biosensing platform based on luminescent nanoparticles and a microfluidic biochip with machine vision algorithm analysis for efficient tumor marker detection. The platform offers high sensitivity, noninvasive sampling, and portable design for early cancer screening and monitoring.
Professor Garry Duffy joins RCSI with a unique combination of institutional knowledge and fresh leadership perspective, focusing on integrating excellence in health sciences education with innovative patient-centred research. He aims to build on the university's heritage by enhancing anatomical education and pioneering research in rege...
Researchers at the Henryk Niewodniczanski Institute of Nuclear Physics have developed wound dressings containing the antibacterial drug metronidazole, which can be released in a controlled manner. The mats are made from electrospun polymer fibers and could potentially be used to treat infections.
Scientists replace toxic additives in hydrogels with D-sorbitol, a safe sugar alternative found in chewing gum, to create bioelectronic devices that are soft, safe, and integrated with natural tissue. The new material has increased biocompatibility and improved electronic performance.
Researchers engineered human spleen into bioreactor capable of curing diabetes and growing functional organs. The spleen's unique structure hosts billions of transplanted cells and provides a nutrient-rich environment for cell growth.
Researchers developed a new method to study mechanical proteins, revealing that disrupting protein titin causes muscle disease. The technique allows for targeted analysis of protein mechanics, paving the way for new therapeutic strategies.
The Berggren Center for Quantum Biology and Medicine will merge quantum technology with biology to transform medicine, driving the development of revolutionary quantum tools and cultivating bilingual scholars. Researchers will translate quantum advances into clinical solutions, enabling new diagnostics and therapies.
Researchers developed self-propelled ferroptosis nanoinducers to enhance cancer therapy by inducing programmed cell death. The nanotherapeutics exhibited enhanced diffusion and deep tumor penetration while maintaining biocompatibility.
Researchers at UH found cells can detect weak electric fields due to active matter in the cell membrane. This discovery could lead to breakthroughs in medical devices, biosensors, and disease therapies.
Researchers developed stable MXene-coated contact lenses providing enhanced protection against electromagnetic radiation. The lenses exhibited a rapid temperature rise when exposed to microwave heating, indicating strong EMR absorption and dissipation.
Researchers used breath analysis to monitor general anesthesia in children, achieving results comparable to blood tests. The method also detected oxidative stress and potential complications, enabling early detection and prevention.
Researchers use MRI and NASA-inspired negative-pressure pants to improve stress tests, revealing hidden heart issues. The technology transforms heart imaging, making it possible to detect real differences in heart performance.
Researchers developed LUCAS, a rapid and portable diagnostic tool that creates stronger and longer-lasting bioluminescence signals, enabling accurate detection of SARS-CoV-2, HIV, HBV, and HCV in patient samples. The tool achieved an average accuracy of over 94% in detecting viruses within 23 minutes.
A Virginia Tech professor has received a proof-of-concept grant to further develop a chemical compound that could help promote weight loss by increasing mitochondrial activity. The compound, named BAM15, shows promise in preclinical studies without affecting food intake or muscle mass.
The article discusses recent advancements in pipeline safety technologies, including defect detection, environmental risks monitoring, and structural integrity assessment. The integration of high-grade steel, large-diameter pipelines, and unconventional energy sources has introduced new complexities to pipeline safety.
Dr. Natalie Artzi joins the Wyss Institute as Associate Institute Director, working closely with Don Ingber to shape strategic direction and advance research and translation efforts. She leads a world-class research program focused on developing tissue- and cell-responsive nanostructures for disease tracking and treatment.
Researchers at Virginia Tech's Fralin Biomedical Research Institute developed a peptide therapy called JM2 that targets cancer cells' ability to renew and regrow. The treatment significantly slows tumor growth in animal models and disrupts the maintenance of treatment-resistant cancer cells.
Researchers developed a metalens-based microscope that achieves both wide field of view and high-resolution imaging in a compact design. The system uses a doublet configuration and annular illumination to overcome traditional metalens limitations, enabling practical applications in biomedical imaging.
Texas A&M University researchers have developed a customizable vessel-chip method that can mimic various blood vessel structures, enabling more accurate models of vascular disease. The chip technology enables patient-specific research and pharmaceutical testing, with the potential to cure vascular diseases.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
Researchers at TU Wien have developed a method to create artificial blood vessels using ultrashort laser pulses, enabling the creation of mini organ models with precise control and reproducibility. The technology has been successfully applied to liver tissue models, resulting in improved metabolic activity and adequate nutrient supply.
The COLD-TUG test measures the time required for prosthetic donning and mobility in lower-limb amputation patients. Researchers found that patients with bone-anchored prostheses can don their prosthesis significantly faster, saving up to 61 seconds per session.
The new 3D-printed device, STOMP, enhances tissue-engineering methods by allowing for precise control over cell types and spatial arrangement. This enables scientists to model complex diseases and recreate natural habitats of cells, paving the way for advancements in biomedical research.
A joint research team from POSTECH and Hanyang University developed a personalized stimulation control mechanism using evoked compound action potential feedback mechanisms to treat urinary disorders. This technology enables precise adjustment of tibial nerve stimulation in real-time, based on individual nerve responses, improving patie...
Researchers discovered a DNA switch in TB bacteria that regulates growth and gene expression. By targeting this process, new antibiotics could be developed to make the bacteria easier to eliminate.
Seven Clusters of Excellence at LMU Munich have been approved for funding, covering a broad range of fields from systems neurology to quantum science. The successful clusters reflect the university's exceptional commitment and cooperation with partners.
A Johns Hopkins Medicine study finds that SARS-CoV-2 corrupts white blood cells, specifically neutrophils, to impair the production of immune cells critical for fighting COVID-19. This reprogramming may lead to severe COVID cases by weakening the immune response against the virus.
Triboelectric and piezoelectric nanogenerators convert mechanical energy into electrical energy, enhancing robotic autonomy and efficiency. The technology has the potential to reshape future robotic capabilities, particularly in industrial automation, healthcare, and smart home applications.
Researchers at Rice University have developed a novel personalized medicine approach for addressing movement impairments. The Neuromusculoskeletal Modeling (NMSM) Pipeline software allows clinicians to work in collaboration to construct personalized computer models of individual patients, leading to more effective orthopedic surgery, p...
A new AI system, MedGaze, is designed to emulate how radiologists visually interpret chest X-rays. By replicating expert attention, it helps train future specialists and improve the efficiency of hospitals through better workflow management.
A study led by Johns Hopkins Medicine found a genetic mutation, F722fs, in the MMS22L gene that is associated with a higher risk of prostate cancer. The researchers identified this mutation in Ashkenazi Jewish men and found it was linked to increased sensitivity to a specific anticancer therapy.
UT Dallas bioengineers have created an enhanced light-activated immunotherapy approach to target advanced stomach cancer. Lab-designed molecules are primed with far-red or near-infrared light to activate the immune system against stubborn cancer cells, reducing side effects.
Researchers at Boston University School of Medicine discovered that PAX3 mainly uses its paired domain to bind to DNA and turn on genes promoting cell growth and survival. The study suggests that targeting the paired domain of PAX3 could be an effective way to treat melanoma.
A new study describes a promising new type of auditory brainstem implant that could benefit people who are deaf due to NF2 and other severe inner ear abnormalities. The soft, flexible implant bypasses damaged auditory structures and directly stimulates the brainstem's sound-processing region.
A new technique using focused sound waves and microbubbles has shown great promise in treating debilitating brain lesions called cerebral cavernous malformations. The approach has halted the growth of lesions almost entirely, offering a potential paradigm shift in treatment.
Researchers analyzed data from a wearable device to find that women's physical activity levels are less variable and more predictable than men's. The study also found no significant difference in physical activity levels between individuals with and without menstrual cycles.
The University of Utah is partnering with XPRIZE to improve healthy aging through a 7-year, $101 million global competition. The partnership aims to validate the science of competing teams working towards extending health spans for aging populations.
New research from Binghamton University reveals that the topography patterns of wrinkled fingers remain constant after multiple immersions. The study found that blood vessels beneath the skin contract and move in relation to other vessels, resulting in consistent wrinkles.