Articles tagged with Biomedical Engineering
Researchers from University of Toronto Engineering demonstrate that bending silicone rubber medical devices can form 'microcracks' perfect for colonizing bacteria. Bacteria prefer to attach in these microscopic cracks, leading to the formation of potentially harmful biofilms.
Researchers at Washington University in St. Louis have found a way to enhance glymphatic transport using focused ultrasound with microbubbles, opening new opportunities for studying brain diseases and function. The non-invasive method shows promise for potentially mitigating neurodegenerative diseases like Alzheimer's and Parkinson's.
Researchers at Nanyang Technological University found that cells near wavy shaped wounds moved in a swirling manner, while those near straight wounds moved in straight lines. This discovery reveals that the swirling motion is crucial for gap-bridging and accelerates wound healing in wavy wounds.
A team led by Professor Timo Betz has developed a 3D cell culture chamber to grow muscle and other tissue using high-resolution microscopy. The new system will enable scientists to mimic the mechanical situations that confront various living tissues in serious conditions, reducing animal testing and costs.
Researchers developed 'smart' coatings that monitor strain on implants to prevent infection and provide early failure warning. The coatings, inspired by dragonfly and cicada wings, integrate flexible sensors with antibacterial surfaces.
The University of Southern California has launched a $1 billion-plus initiative for computing research and education, focusing on AI, machine learning, data science, and emerging technologies. The initiative aims to integrate digital literacy across disciplines and prepare students for a more tech-intensive world.
The Spitrobot simplifies sample preparation for time-resolved crystallography, allowing non-specialist groups to conduct experiments that previously required expert expertise. This technology accelerates research in enzymatic mechanisms and enables broader applications in biotechnology and disease-related problems.
Scientists have successfully regulated the flow of single molecules in a solution by opening and closing a nanovalve, which could revolutionize chemical and biochemical synthesis. This technology has the potential to detect pathogens with high sensitivity and create new materials for various industries.
A team of researchers developed a multi-organ chip on-a-chip that applies 3D cell printing technology to closely replicate the pathological environment of type 2 diabetes. The chip shows a correlation between visceral fat and T2D, as well as impaired retina cell function, indicating potential complications.
The PRISM-LT project aims to create an adaptable platform for 3D bioprinting of living tissue with dynamic functionalities and predictable shapes, using a novel tunable bioink that fosters a symbiotic relationship between stem cells and microorganisms.
Researchers have built a new model to examine Usher Syndrome, a leading cause of combined deafness and blindness. The model replicates the visual problems not addressed by previous models, offering insight into strategies for designing therapeutic interventions.
A team of researchers has developed a method that uses electric stimulation to accelerate wound healing, making it possible for wounds to heal up to three times faster. The technique involves applying an electric field to damaged skin, which helps guide skin cells in the same direction, promoting faster healing.
Researchers at Duke University have successfully improved the resolution of Magnetic Resonance Imaging (MRI), capturing images of a mouse brain with unprecedented sharpness. The breakthrough allows for the visualization of microscopic details within the brain, enabling new insights into neurodegenerative diseases such as Alzheimer's an...
A research group has successfully developed an adsorbent material that can selectively recover rare earth elements from hot spring water, a process expected to contribute to a metal resource-circulating society. The method uses environmentally friendly and inexpensive materials, such as baker's yeast and trimetaphosphate.
Researchers have developed a novel 3D printing strategy that preserves the folding structure and molecular function of various biopolymers, enabling precise control over size and geometry at submicron resolution. The technique allows for the production of 3D biopolymeric architectures with functional integrity and biofunctions.
A multidisciplinary research team has developed a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak. The protein, Griffithsin, disables a wide range of viruses, including COVID-19, and can be manufactured without living cells.
Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...
Scientists have developed a new microfluidic sperm selection device to improve IVF success rates. The device replicates the natural sperm selection process, resulting in an 85% improvement in DNA integrity and a 90% reduction in sperm cell death.
OncoMerge uses genetic data to analyze tumor activity and predict future changes. The software detects abnormal gene fusions and mutations affecting protein expression and gene copy numbers, improving the accuracy of cancer modeling predictions.
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
A recent study by UPF's BCN MedTech defines a computational model that simulates protein interactions to pinpoint osteoarthritis causes in each patient. This model enables personalized and efficient treatments, which are currently challenging due to the disease's multifactorial origin.
A research team from Pohang University of Science & Technology has engineered an artificial kidney to detect adverse drug reactions and provide personalized treatment. The team successfully fabricated a glomerular microvessel-on-a-chip that recapitulates the kidney's filtering function and evaluates its response to various toxins.
Researchers from Osaka Metropolitan University have developed a system that converts waste acetone and low CO2 concentrations into biodegradable plastic using artificial photosynthesis. The study successfully synthesized 3-hydroxybutyrate with over 60% efficiency after 24 hours.
A new method using brain signal processing has been developed to categorize different types of depression. The study achieved a 91% accuracy rate in detecting anxious and non-anxious depression, showing promise for improved diagnosis and treatment.
The new center aims to amplify biomedical research and human health applications, fostering collaboration among innovators. BRIC members will have access to resources and support for applying their nuclear physics expertise in new areas.
A team of researchers from POSTECH and Georgia Tech developed a biohybrid 3D printed heart model with integrated sensors to monitor drug-induced cardiotoxicity. The platform enables real-time, continuous monitoring of heart contractions, facilitating the testing of acute and chronic pharmacological effects.
Researchers developed innovative contrast-enhancing agents to tackle limitations of photoacoustic imaging, including low SNR, image contrast, and targeted delivery. The study suggests promising strategies such as photoswitching agents, near-infrared-II agents, and micromotor agents.
Researchers from Kessler Foundation found that transcutaneous spinal stimulation does not interfere with implanted intrathecal baclofen pump delivery systems. However, communication between the pump and its interrogator may be briefly affected due to electromagnetic interference.
Researchers at Harvard University developed a novel RNA sense-and-respond circuit, DART VADAR, which utilizes an enzyme to detect specific molecular markers of disease and cell types. This enables highly specific treatments for various diseases by triggering the translation of therapeutic genetic payloads.
A team of researchers developed a transfer-tattoo-like cell sheet that can be directly applied to targeted surfaces, facilitating cutaneous wound healing and promoting skin tissue regeneration. The system leverages natural cell migration between surfaces, eliminating the need for external stimuli and detachment processes.
Scientists create modified E. coli bacteria that cannot be infected by viruses while minimizing gene escape into the wild. This breakthrough technology has implications for reducing viral contamination in biotechnology production, such as insulin production and biofuel manufacturing.
Scientists create hybrid composite scaffolds with aligned nanofibrous architectures to improve cell seeding efficiency, proliferation rates, and morphogenesis. The findings have potential applications in tissue repairing and regenerative medicine.
A new coating material developed by Korean researchers facilitates bone regeneration and attracts osteo-progenitor cells, significantly improving the success rate of dental implants. The coating, loaded with BMP-2, prevents non-osteogenic cell invasion and induces high bone differentiation in a short period.
Researchers at University of Technology Sydney have successfully created personalized 'bio-inks' from patients' own stem cells, which are then used to 3D-print cardiac tissues to repair areas of dead tissue. This technology shows promise in treating heart failure and may reduce the need for expensive and traumatic heart transplants.
Scientists at the Institute of Nuclear Physics Polish Academy of Sciences have developed new nanocomposites that spontaneously and continuously kill microorganisms. The composites use silver ions or copper ions to destroy cell membranes and oxidative shock, respectively, providing a durable and safe solution for biocidal materials.
Researchers developed a hydrogel-based sensor to monitor overactive bladder activity in real-time. The sensor measures both mechanical and bioelectrical activities, allowing for simultaneous monitoring and neural stimulation. This breakthrough has the potential to improve treatment outcomes and minimize side effects.
Scientists have developed a new technique using tissue-embedded nanoelectronic devices to study the functional maturation of stem-cell derived heart tissues. The research found that co-culturing stem-cell-derived cardiomyocytes with endothelial cells enables faster and more efficient maturation, with significant implications for engine...
A team of POSTECH researchers has developed a deep learning-based multimodal fusion network for segmentation and classification of breast cancers using B-mode and strain elastography ultrasound images. The method achieved high accuracy in distinguishing benign from malignant lesions, outperforming conventional methods.
Researchers found that no single helmet design consistently reduced concussion incidence, with the back of the helmet showing vulnerabilities. The study suggests combining lab tests with field-based impact tracking could provide better protection for athletes.
A University of Michigan study suggests that exhaled breath contains unique volatile organic compounds (VOCs) that can mark distinction between COVID-19, variants and non-COVID illnesses. The researchers developed a portable gas chromatography device to analyze breath samples with high accuracy.
A novel AI architecture, relational reasoning network, accurately identifies anatomical landmarks in CT scans for orthodontic treatments. The model learns spatial relationships between landmarks without explicit image segmentation, achieving accuracy comparable to conventional methods.
A novel deep brain simulation approach has been developed to treat intractable epilepsy, with the potential to be a safer and more effective treatment than conventional methods. The sequential narrow-field stimulation method accurately detects seizure onset and alleviates symptoms while minimizing side effects.
A new rehabilitation strategy for brain injuries is being developed by OU researcher Yuan Yang, who will use multi-modal MRI scans and electrical neural activity scans to assess changes in motor control. The goal is to reduce recovery time and healthcare costs for stroke survivors.
A POSTECH research team developed a machine learning model that accurately predicts cancer type-specific driver mutations, shedding light on distinct pathological mechanisms across various tumors. The model's performance outperformed current leading methods of detection, with better accuracy and sensitivity.
Scientists at Aarhus University and Berkeley Laboratory developed a method called RNA origami to design artificial RNA nanostructures. The technique allowed for the discovery of rules and mechanisms for RNA folding that will make it possible to build more ideal RNA particles for use in RNA-based medicine.
Researchers developed a microfluidic model of vascular malformation caused by PIK3CA mutation, allowing them to study disease mechanisms and test treatment efficacy. The model successfully replicated the disease's manifestations and responded to alpelisib, a newly approved PIK3CA inhibitor.
Researchers at City University of Hong Kong developed a wireless, soft e-skin for interactive touch communication in the virtual world. The e-skin can detect and deliver the sense of touch, enabling one-to-multiuser interaction and overcoming the limitations of space and distance.
A POSTECH research team has developed a deep-learning approach to enhance resolution and speed in photoacoustic computed tomography (PACT) imaging. The technique enables high-resolution, real-time whole-body imaging of animals and monitors tissue movement in the heart, kidney, and brain.
Scientists from SUTD design a novel thermal-based therapy nano-system that destroys over 20% of pancreatic cancer cells using microsecond electrical pulses, improving cancer cell targeting accuracy and bio-compatibility. The introduction of the M13 virus enhances electro-thermal therapy performance by assembling more on cancer cells.
Researchers developed an antibiotic that cured mice infected with nearly untreatable bacteria, with virtually undetectable resistance to the drug. The unique mechanism of action targets multiple bacterial functions, disrupting the bacterial membrane and leading to broad-spectrum antibacterial activity.
Researchers at City University of Hong Kong develop a self-charging electrostatic face mask that can continuously replenish its electrostatic charge through the user's breathing. The mask provides high-efficiency airborne particle removal with 95.8% effectiveness after 60 hours of testing.
A team of Brown researchers has developed a new, highly accurate method for detecting antidepressants in patients using liquid chromatography tandem mass spectrometry. The technique requires minimal biological samples and can be fully automated using liquid-handling robots.
A team of researchers from UNC and CDC developed an injectable implant that can release HIV PrEP medications for up to six months, providing full protection. The technology has shown promise in non-human primates and could potentially be adapted for human use.
Assistant Professor Tracy Hookway at Binghamton University has received a five-year, $500,000 National Science Foundation CAREER Award to study the interplay between sympathetic and parasympathetic neurons on heart cells. Her research could lead to better understanding of cardiac health, including heart transplants, neurodegenerative d...
Researchers at the University of Missouri have designed a soft and breathable material that can be worn on the skin without causing discomfort. The material, made from liquid-metal elastomer composite, has integrated antibacterial and antiviral properties to prevent the formation of harmful pathogens.
Researchers at Rice University have developed a self-assembling peptide ink that enables the 3D printing of complex structures with cells, which can then be used to grow mature tissue in a petri dish. The ink allows for control over cell behavior using structural and chemical complexity.
Researchers at Duke University have created a new approach to controlling cellular biochemical processes by building synthetic compartments that isolate biomolecules. This technique has the potential to be used to understand and fight disease, including the spread of antibiotic-resistant pathogens.
Scientists have identified genes that play key roles in the development of coronary artery disease (CAD), a leading cause of death worldwide. The study found notable differences in gene activity between males and females, as well as between cells that were multiplying and those that were not.
A University of Houston research team has developed a new method for early diagnosis and monitoring of lupus nephritis using a smartphone-based test. The test assesses the levels of ALCAM protein in urine, showing high diagnostic accuracy for renal pathology activity in active lupus nephritis.
A new smart contact lens has been developed to diagnose and treat glaucoma by monitoring intraocular pressure in real-time and releasing the appropriate amount of medication. The lens, created by a POSTECH research team, uses a flexible drug delivery system and wireless power and communication system.