A new deep learning-based model called Highlights on Target Sequences (HoTS) predicts binding between drugs and target molecules, providing interpretable results. The model can predict target proteins' binding regions and interactions with drugs without a 3D complex.
SourceGIST (Gwangju Institute of Science and Technology)·JournalJournal of Cheminformatics·TypeComputational simulation/modeling·DateApr 5, 2022
Studies in mice show that immune cells prevent stem cell repair after volumetric muscle loss, a common type of injury such as gunshot wounds or car accidents. This understanding could lead to new treatment strategies and potentially restore function and prevent limb loss.
SourceUniversity of Michigan·JournalProceedings of the National Academy of Sciences·DateApr 5, 2022
A GE Research-led team has demonstrated the ability to prevent or reverse diabetes in preclinical model systems using ultrasound-based bioelectronic medicine. The team's findings, published in Nature Biomedical Engineering, represent a significant milestone in this field and pave the way for future clinical translation.
SourceGeneral Electric (United States)·JournalNature Biomedical Engineering·TypeRandomized controlled/clinical trial·DateMar 31, 2022
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Rice University engineers have developed a tiny, wireless device that can stimulate nerves and treat neurological diseases. The implant, powered by a magnetic transmitter, uses blood vessels as guides to reach targeted nerves.
SourceRice University·JournalNature Biomedical Engineering·TypeExperimental study·DateMar 31, 2022
A new technology called MediSCAPE has been developed by Columbia Engineers that can capture real-time cellular detail in living tissues. This allows doctors to make informed decisions about tumor removal without needing to remove tissue and wait for pathology results.
SourceColumbia University School of Engineering and Applied Science·JournalNature Biomedical Engineering·DateMar 28, 2022
Researchers will investigate the downstream effects of SARS-COV-2 on aortic valve pathology. The study aims to understand the cause-and-effect relationship between COVID-19 and heart valve damage.
In an animal study, researchers created an implantable biotechnology called MASTER that produces and releases CAR-T cells for attacking cancerous tumors. This technology reduces the manufacturing time from weeks to hours, increasing efficiency and effectiveness.
SourceNorth Carolina State University·JournalNature Biotechnology·TypeExperimental study·DateMar 24, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers at Duke University have developed a device that manipulates particles and cells using complex sound waves, enabling selective pairing of individual cells to measure adhesion forces. This technology could lead to personalized medicine by allowing doctors to determine treatment for individual cancer patients.
SourceDuke University·JournalNature Materials·TypeExperimental study·DateMar 24, 2022
Researchers developed long-lived biological computers using RNA, which can persist inside cells. Unlike DNA-based devices, these RNA circuits are dependable and versatile, enabling continuous production in living cells.
SourceNational Institute of Standards and Technology (NIST)·JournalScience Advances·DateMar 23, 2022
Researchers at the University of Houston have developed a novel technology to monitor membrane protein trafficking in real-time using bioluminescence. This allows for the study of cellular processes and drug development for heart disease, metabolic disorders, cancer, infectious diseases, COVID-19, and others.
SourceUniversity of Houston·JournalCommunications Biology·DateMar 22, 2022
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
The new center aims to develop quantitative imaging markers to reduce subjectivity in medical image diagnosis and improve consistency. Researchers will explore cutting-edge imaging modalities and extract effective image features from existing clinical imaging modalities to aid in cancer detection and treatment.
Researchers have developed a robust and stretchable ECM hydrogel-based membrane with nanofiber scaffolds, mimicking native basement membranes. This membrane enables cyclic stretching motions and maintains stable structure over extended cell culture periods, contributing to fabricating sophisticated artificial organs.
SourcePohang University of Science & Technology (POSTECH)·JournalBiofabrication·DateMar 21, 2022
Research at the University of Michigan has developed a method to quickly recognize wrong twists and chemical structures in packaged drugs using terahertz radiation. This technique could help diagnose harmful accumulations of twisted molecules in the body, including bladder stones and Alzheimer's disease.
SourceUniversity of Michigan·JournalNature Photonics·DateMar 21, 2022
A POSTECH research team has developed a technology to select genes from animal models that accurately mimic human diseases. This allows for the prediction of success or failure of animal disease models before making them, leading to more effective new drugs.
SourcePohang University of Science & Technology (POSTECH)·JournalNucleic Acids Research·DateMar 16, 2022
Researchers at Karolinska Institutet have found a way to stabilize the cancer-suppressing protein p53 by adding a spider silk protein, creating a more potent variant. This discovery has potential as an approach for cancer therapy.
SourceKarolinska Institutet·JournalStructure·TypeExperimental study·DateMar 14, 2022
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
New research from University of Utah biomedical engineer Jessica Kramer reveals that human mucus and saliva may prevent the spread of coronaviruses when dry on a surface. Mucins in mucus form a barrier around live virus, preventing infection by binding to sugars on viruses instead of cells.
SourceUniversity of Utah·JournalACS Central Science·TypeExperimental study·DateMar 9, 2022
Researchers created a new device called the lymphangion-chip, which models a section of a lymph vessel and can recreate conditions such as lymphedema. This innovation could lead to better understanding of mechanical forces regulating lymphatic physiology and pathophysiology.
SourceTexas A&M University·JournalLab on a Chip·DateMar 9, 2022
Researchers at the University of Virginia Health System have identified a potential way to treat obesity and type 2 diabetes in women by targeting a specific gene called KLF14. Increasing KLF14 abundance in fat cells may help alleviate metabolic abnormalities, including slower metabolic rates and less efficient triglyceride management.
SourceUniversity of Virginia Health System·JournalDiabetes·DateMar 9, 2022
Researchers have identified a protein in tick saliva that can relieve chronic pain and itching, offering a potential alternative to traditional painkillers. The findings could lead to a new medication that is more effective and safer than current options.
SourceDurham University·JournalFrontiers in Pharmacology·TypeExperimental study·DateMar 8, 2022
Researchers at Rutgers University have successfully stabilized an enzyme that degrades scar tissue resulting from spinal cord injuries, promoting tissue regeneration. The study used AI-driven liquid handling robotics to synthesize and test copolymers that stabilize the enzyme, offering new hope for patients with spinal cord injuries.
SourceRutgers University·JournalAdvanced Healthcare Materials·TypeExperimental study·DateMar 7, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers will study temporomandibular joint function and disorders, aiming to understand the stresses on the joint before degeneration and develop new treatments. The project is a collaboration between Clemson University, Medical University of South Carolina, and National Institute of Dental and Craniofacial Research.
Researchers developed smart contact lenses that emit far-red light to treat diabetic retinopathy. The study showed the lenses prevented retinopathy in diabetic animal models, demonstrating their safety and effectiveness.
SourcePohang University of Science & Technology (POSTECH)·JournalAdvanced Science·DateMar 7, 2022
Researchers developed a hair-thin patch that can measure pulse wave signals with high accuracy, creating a 2D pressure map on the wrist. This technology enables at-home diagnosis of cardiovascular diseases and pre-diagnosis of related conditions.
SourcePohang University of Science & Technology (POSTECH)·JournalACS Nano·DateMar 3, 2022
Researchers have discovered a genetic difference in the meniscus that makes about 50% of females more prone to developing knee osteoarthritis than males or other females. The study suggests potential for a blood test to identify high-risk individuals, allowing for early interventions and prevention strategies.
SourceUniversity of Alberta·JournalFrontiers in Bioengineering and Biotechnology·DateMar 2, 2022
A team of researchers has made a breakthrough in understanding how the brain processes visual information by studying populations of neurons across multiple brain areas. The study reveals that feedforward and feedback signaling involve different neural activity patterns, shedding new light on how the brain communicates with itself.
SourceCollege of Engineering, Carnegie Mellon University·JournalNature Communications·DateMar 1, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A new form of drug delivery microparticle mimics the properties of a red blood cell, enabling controlled release of drugs and targeting specific destinations. The goal is to bypass the body's filtration systems, allowing for improved efficacy and reduced negative side effects.
SourceUniversity of Arizona College of Engineering·DateMar 1, 2022
Remote monitoring of patients with continuous pulse oximetry and heart rate devices was associated with reduced death rates. This technology advance improved patient safety, lowered mortality, and increased accuracy in care.
SourceUniversity Hospitals Cleveland Medical Center·JournalJAMA·TypeLiterature review·DateFeb 25, 2022
A new study by University of Michigan researchers found that genetics play a crucial role in how our bodies respond to vaccines and booster shots. The team identified a specific form of an antibody-related gene that predicts whether boosting will be effective for increasing innate immune responses.
SourceUniversity of Michigan·JournalFrontiers in Immunology·DateFeb 23, 2022
Researchers at RMIT University used high-frequency sound waves to turn stem cells into bone cells, overcoming challenges in mass production and pain associated with extraction. The innovative treatment is faster, simpler, and more efficient than existing methods.
SourceRMIT University·JournalSmall·TypeExperimental study·DateFeb 22, 2022
Researchers have developed a low-cost, easy-to-use focused ultrasound device that can precisely target the mouse brain. The $80 device, created using a 3D printer, has been shown to achieve sub-millimeter targeting accuracy and improve drug delivery outcome.
SourceWashington University in St. Louis·JournalIEEE Transactions on Biomedical Engineering·TypeExperimental study·DateFeb 22, 2022
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Dr. Jansen will test hypotheses on intracellular domain of pLGIC proteins, aiming to gain insights into assembly, chaperone-modulation and functional conformational transitions in various diseases. Her research focuses on neurotransmitter-gated ion channels and their interactions with RIC-3-like chaperone proteins.
SourceTexas Tech University Health Sciences Center·DateFeb 21, 2022
A recent review highlights the effects of different intestinal bacteria on colorectal cancer, exploring new therapies for disease prevention and treatment. Beneficial probiotics, such as Akkermansia muciniphila and Lactobacillus rhamnosus GG, exhibit anticancer properties and reduce CRC cell proliferation.
SourceCactus Communications·JournalChinese Medical Journal·TypeLiterature review·DateFeb 21, 2022
A new HMI system, Robotic VR, allows users to teleoperate robots with precision and feel, enabling complicated tasks such as Covid-19 swab tests and patient care. The system provides immersive feedback via Bluetooth, Wi-Fi, and the internet.
SourceCity University of Hong Kong·JournalScience Advances·TypeExperimental study·DateFeb 21, 2022
Developed by University of Seville researchers, the new methodology has a sensitivity of 100% and specificity of 87.5%. It can detect SARS-CoV-2 in saliva and synthetic viruses with minimal equipment and training.
SourceUniversity of Seville·JournalScientific Reports·DateFeb 18, 2022
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers found that kitchen sponges provide an optimal environment for microbial diversity by mimicking the separation and communal spaces found in healthy soil. This complex structure supports both solitary and diverse bacterial communities, leading to higher biodiversity levels.
SourceDuke University·JournalNature Chemical Biology·TypeExperimental study·DateFeb 17, 2022
A new machine learning process has been developed to identify and classify hip fractures from X-rays, achieving 92% accuracy and confidence. This approach aims to improve patient outcomes, reduce care costs, and alleviate the bottleneck of unreported radiographs in the UK.
SourceUniversity of Bath·JournalScientific Reports·TypeComputational simulation/modeling·DateFeb 11, 2022
Researchers at City University of Hong Kong have developed a novel droplet manipulation method called WRAP, which can transport micro-sized droplets using electromagnets or programmable electromagnetic fields. The method overcomes challenges in traditional magnetic actuation, such as contamination from added magnetic particles.
SourceCity University of Hong Kong·JournalNature Communications·TypeExperimental study·DateFeb 11, 2022
Researchers developed a fully autonomous biohybrid fish from human stem-cell derived cardiac muscle cells that recreates the muscle contractions of a pumping heart. The device has two layers of muscle cells that work together to propel the fish for over 100 days.
SourceHarvard John A. Paulson School of Engineering and Applied Sciences·JournalScience·DateFeb 10, 2022
Researchers at UC Davis Health have developed an engineered antibody, FuG1, that can interfere with the cell-to-cell transmission ability of SARS-CoV-2. The approach targets the furin enzyme, which is critical for viral transmissibility, and could be added to existing SARS-CoV-2 antibody cocktails.
SourceUniversity of California - Davis Health·JournalMicrobiology Spectrum·TypeExperimental study·DateFeb 9, 2022
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers developed an optogenetic approach to control parathyroid hormone secretion and prevent secondary hyperparathyroidism-associated bone loss. The method partially attenuated SHPT-associated bone loss in animal models, suggesting its potential as a treatment for hyperparathyroidism-induced bone disease.
SourceChinese Academy of Sciences Headquarters·JournalNature Communications·DateFeb 9, 2022
Markita del Carpio Landry, a young immigrant scientist, receives the Vilcek Prize for Creative Promise for her groundbreaking research on neurochemical communication and gene-editing technologies. Her work aims to address medicine's most compelling problems, including aberrations in neurotransmitter signaling.
The IEEE forum identified four major challenges to address during the pandemic: healthcare, screening, tracing, and treatment. The panel highlighted socioeconomic and education status as critical factors impacting mortality rates and hospital admission lengths.
SourceUniversity of Houston·JournalIEEE Journal of Biomedical and Health Informatics·DateFeb 7, 2022
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
Biomedical engineers at Duke University have developed a gene therapy that helps heart muscle cells electrically activate in live mice. The approach features engineered bacterial genes that code for sodium ion channels, which could lead to therapies to treat electrical heart diseases and disorders.
SourceDuke University·JournalNature Communications·TypeExperimental study·DateFeb 4, 2022
Researchers at Rosalind Franklin University have identified a new therapeutic approach for treating cystic fibrosis. The treatment uses antisense oligonucleotides to restore CFTR function by removing stop mutations. This strategy has shown promise in treating CF patients with class I mutations and similar types of mutations.
SourceRosalind Franklin University of Medicine and Science·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 3, 2022
Researchers have developed a prototype insulin-loaded patch that comfortably sticks to the inside of a person's cheek, offering a less invasive way to manage blood sugar levels. The patch, activated by heat, releases insulin into the bloodstream several times faster than through skin, showing promise for diabetes treatment.
SourceAmerican Chemical Society·JournalACS Applied Bio Materials·DateFeb 2, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A multidisciplinary research team from the University of Pittsburgh seeks to improve vascular graft integration by developing fully biodegradable tissue-engineered vascular grafts. The goal is to keep compliance-matched as it degrades and remodels, reducing long-term graft failure rates.
UCSF cancer biologist Hani Goodarzi is recognized for his groundbreaking research on cancer metastasis and novel molecular players. His work has led to the discovery of a protein driving breast cancer metastasis and orphan noncoding RNAs in cancerous cells.
Researchers at Brown University have developed a new laboratory test model to investigate fibrosis treatments without the use of animals. The model uses human cells and replicates not only the structure of human tissue but also its mechanics, enabling scientists to study the underlying mechanisms of fibrosis and test potential treatments.
SourceBrown University·JournalAdvanced Science·TypeComputational simulation/modeling·DateFeb 1, 2022
Researchers at MIT have developed a pill that can deliver RNA to the stomach, potentially making vaccines easier to tolerate and treat gastrointestinal diseases. The capsule is designed to release RNA in the stomach, where it can stimulate an immune response without being degraded by digestive enzymes.
SourceMassachusetts Institute of Technology·JournalMatter·DateJan 31, 2022
A new diagnostic tool combines grayscale B-mode and strain elastography ultrasound imaging to detect breast cancer with high accuracy. The model achieved a detection rate of 90% in the study, surpassing individual models trained on either B-mode or SE imaging alone.
SourcePohang University of Science & Technology (POSTECH)·JournalIEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control·DateJan 27, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers at Northwestern University have developed a novel microfluidic device that can efficiently harvest and sort tumor-eating immune cells from tumors. This technology has shown dramatic results in shrinking tumors in mice compared to traditional methods.
SourceNorthwestern University·JournalNature Biomedical Engineering·DateJan 27, 2022
Case Western Reserve University researchers create nanoparticles that generate a protein mesh to stabilize blood clots and reduce blood loss. The technology could help save lives by rapidly stabilizing clots to reduce blood loss from traumatic injuries.
SourceCase Western Reserve University·JournalScience Translational Medicine·DateJan 26, 2022
Researchers at OHSU are developing a new approach to scientific imaging to study the dynamic organization of cells by examining how tiny molecules make cells work. The W. M. Keck Foundation has awarded $1 million to develop a one-of-a-kind imaging and computational system.
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A research team has developed a new cancer treatment that targets lymph nodes using a prodrug that selectively reacts with glutathione to release nitric oxide. In a metastasis mouse model, the mice treated with the drug showed significantly reduced weight of metastatic cancer cells and improved survival rates.
SourcePohang University of Science & Technology (POSTECH)·JournalAdvanced Science·DateJan 26, 2022
Researchers at Kumamoto University developed a novel 'supermolecular' material that binds to protein drugs, prolongs their effect without impairing activity, and improves overall drug performance. The material, called PEG-PRX, adds polyethylene glycol chains to proteins without compromising biological action.
SourceKumamoto University·JournalMaterials Today Bio·TypeExperimental study·DateJan 25, 2022
Researchers at the University of Oklahoma have developed a molecular framework that solves the challenge of predicting peptide structures. The framework bridges experimental and computer sciences, enabling the use of machine learning and artificial intelligence to model peptide structures for materials engineering.
SourceUniversity of Oklahoma·JournalScience Advances·DateJan 25, 2022
Researchers at University of Washington developed a fast, cheap test for COVID-19 that combines speed of antigen tests with accuracy of PCR tests. The Harmony COVID-19 test detects genetic material from SARS-CoV-2 virus with 97% accuracy and provides results in under 20 minutes.
SourceUniversity of Washington·JournalScience Advances·TypeExperimental study·DateJan 24, 2022
A team of researchers at Harvard's Wyss Institute and ETH Zurich have developed a computational approach to identify genomic safe harbors (GSHs) with high potential for safe insertion of therapeutic genes. The study validated two GSH sites in adoptive T cell therapies and in vivo gene therapies for skin diseases.
SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalCell Reports Methods·TypeExperimental study·DateJan 24, 2022
Aranet4 Home CO2 Monitor
Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers from Osaka University created patient-derived heart cells that exhibit reduced contractility and impaired desmosome assembly when carrying a mutation associated with arrhythmogenic cardiomyopathy. Replacing the mutated gene restored normal function, suggesting a potential treatment approach for this disease.
SourceOsaka University·JournalStem Cell Reports·TypeExperimental study·DateJan 24, 2022
Researchers at MIT have developed an all-in-one approach to diabetes treatment, streamlining the process of blood glucose measurement and insulin injection. The new device can automate procedures such as pricking skin, collecting blood, calculating glucose levels, and dispensing insulin, reducing the need for multiple devices and makin...
SourceMassachusetts Institute of Technology·JournalJournal of Controlled Release·DateJan 20, 2022