Articles tagged with Biomedical Engineering
Researchers at Duke University developed a holographic system that can image and analyze tens of thousands of cells per minute to spot signs of disease. The technique distinguished between healthy samples and cancerous or pre-cancerous cells with nearly 100% accuracy, using just four basic cellular physical parameters.
Researchers create a wireless ecosystem with implantable devices and IoT infrastructure to control animal brain circuits remotely, speeding up neuroscience studies and uncovering basic brain functions.
Researchers used X-ray technology to study human chromosomes in their native state, discovering a fractal structure and a packing mechanism that condenses DNA into one-millionth its size. The findings could have significant implications for understanding genetics and uncovering the structures of other materials, such as viruses.
UMass Lowell researchers will focus on four projects to better protect employees in various professions, including healthcare workers and teachers. The five-year grant funding supports studies on work-life balance, engagement, burnout, and implementing programs to deal with job stressors.
A team of researchers led by Guy Genin and Stavros Thomopoulos found a previously unknown fibrous architecture in the shoulder joint, revealing new features of the attachment system. The discovery sheds light on how the rotator cuff functions and why repairs fail frequently.
Researchers at Durham University have developed a sugar-containing polymer coating that can repair damaged artificial joint implants by mimicking the way cartilage works to lubricate human joints. The coating uses water to create a slippery surface, protecting the surfaces from wear and tear.
Researchers have developed a prostate cancer organoid that can mimic the patient-specific microenvironment, opening up new avenues for targeted treatments. The study reveals that extracellular matrix regulates EZH2 activity and efficacy of inhibitors, as well as identifies potential new therapeutic targets like DRD2.
Biomedical engineers found that individual neurons fire in seconds-long, coordinated cascades during rest, triggering activity across the brain. This organized pattern of activity may be linked to arousal and memory systems, with implications for understanding cognitive decline and Alzheimer's disease.
The RT-CIRAM system analyzes public-domain data to determine the best times to avoid crowds and minimize COVID-19 infection risk. The mobile phone app provides personalized recommendations based on user input and factors like vaccination rates and cultural norms.
Researchers developed an AI method to correct speed of sound aberrations in photoacoustic images, resulting in improved image quality and resolution. The technique reduced streak artifacts by up to 5% and increased signal-to-noise ratio by about 25 decibels.
A team of researchers from SUTD and A*STAR Bioinformatics Institute developed a combined electric current 2D material sensor to detect breast cancer cells. The ultra-sensitive sensor can identify electrical signals from a record low number of cancer cells, offering new possibilities in the field of biosensing.
Researchers at Harvard's Wyss Institute have developed a microfluidic Organ Chip device that accurately models cystic fibrosis lung airway pathology. The model replicates key pathological hallmarks, including mucus layer changes and inflammatory responses, providing a comprehensive preclinical human model for investigating new therapies.
A new study by USC researchers uses GANs to generate synthetic neurological data that can be fed into machine-learning algorithms to improve BCI usability. This approach improved BCI training speed by up to 20 times and enabled rapid adaptation to new subjects.
A study using anonymized health data found that people with poorly managed long-term glycemic control are nearly 50% more likely to require ICU treatment if they contract COVID-19. Metformin, insulin, and corticosteroids may also reduce the risk of severe COVID-19.
Researchers develop new technique DASP, which uses spherical viscoelastic bio-ink particles to create porous 3D structures. The technology has the potential for human islet transplantation to treat type 1 diabetes.
Researchers at POSTECH demonstrate experimental demonstration of negative refraction at visible frequency for the first time, achieving high-resolution images beyond diffraction limit. The study uses a vertical hyperbolic metamaterial to exhibit negative refraction in entire visible domain, overcoming limitations of conventional materi...
A research team developed a treatment for myocardial infarction using mussel adhesive proteins, promoting cell proliferation and migration in damaged heart tissue. The MAP-based microneedle bandage alleviated fibrosis and restored the damaged myocardial wall.
A new liquid biopsy method developed by researchers at Pohang University of Science & Technology (POSTECH) demonstrates high sensitivity and specificity in detecting tumor DNA in the blood. The technique can detect even one to three specific tumor DNAs, offering a promising approach for early cancer diagnosis.
Researchers have made significant breakthroughs in understanding Parkinson's disease, revealing that affected neurons don't die but lose properties. This knowledge opens the door to new therapeutic treatments targeting the cell body, rather than just axons.
Researchers created novel frog models to replicate polycystic kidney disease, allowing for real-time observation of disease processes. AI analysis enabled rapid assessment of disease in the tiny animals.
A team of experts from Tel Aviv University has identified 5 coronavirus proteins responsible for damaging blood vessels. The researchers hope that the identification will lead to the development of targeted drugs that reduce vascular damage in COVID-19 patients.
Researchers are developing a transformative technology called Multiscale Intelligent Convergence (MusIC) to map the complexity of T cells and identify attributes essential for patient benefit. The goal is to create more reliable biomanufacturing of T cell infusion products and engineering potent immune cells.
A team of researchers developed an innovative culture system that enables intestinal epithelial cells to form a three-dimensional villi microstructure. The BASIN system reproduces the structure and function of human intestinal epithelial cells simultaneously in multiple cell culture inserts.
Researchers from Osaka City University found that non-thermal atmospheric pressure plasma (NTAPP) accelerates cell growth and promotes bone regeneration in animal models with critical bone defects. Micro-CT images showed a 1.51 times larger bone volume after 10-minute treatment, while histological analysis confirmed new bone formation ...
Researchers have demonstrated a new technique for cross-sectional medical images without the need for tomography, enabling faster and more accurate imaging. The breakthrough is made possible by ultrafast photon detectors that can precisely determine the arrival times of photons, allowing for reconstruction-free positron emission imaging.
Researchers from FAU investigated G protein-coupled receptors, finding that tailor-made substances can affect receptor dimer formation and behavior. The study revealed the dopamine D3 receptor migrates into the cell interior when bound to a bivalent ligand, altering signal transmission.
Scientists at Harvard's Wyss Institute create eToeholds to target specific diseases, enabling more precise RNA therapy and diagnostic approaches. The technology, developed by James Collins and his team, uses internal ribosome entry sites to produce proteins only when a cell-specific or viral RNA is present.
Researchers at the University of Texas at Arlington have developed a non-invasive wearable device that can accurately measure hemoglobin levels, reducing racial disparities in blood tests. The device uses spectroscopic properties to estimate hemoglobin, showing better accuracy and consistency than current methods.
A new study reveals that certain strains of Cutibacterium acnes (C. acnes) found on healthy skin can prolong the lifespan of Caenorhabditis elegans and help its innate immune system fight against Staphylococcus aureus. RNA sequencing analysis also shows these beneficial strains activate genes related to innate immunity.
A team of scientists successfully created a form of artificial vision for a blind woman using a prosthesis hardwired into her brain. The Moran|Cortivis Prosthesis enabled Gómez to identify lines, shapes, and simple letters evoked by different patterns of stimulation.
Researchers at Technical University of Munich have developed a new X-ray method for respiratory diagnostics using dark-field chest imaging, allowing for early detection and treatment follow-up of respiratory ailments. The technology reduces radiation dose by a factor of fifty compared to traditional computed tomography.
Scientists from the University of Johannesburg found that shining two lasers on adult stem cells accelerates their transformation into different types of cells. The consecutive irradiation increases proliferation and differentiation under laboratory conditions, paving the way for potential therapies to repair damaged tissues.
Researchers developed a graphene-based electrode, the sutrode, to modulate spleen function and immune response in diseases like rheumatoid arthritis and sepsis. The device can control different terminal nerves, increasing precision in organ function regulation.
A computer model developed by the University of Surrey researchers supports Bernard Williams' 40-year-old hypothesis that pressure changes cause fluid in the cavity to 'slosh', generating stress in the spinal cord tissue. The study shows that this process can lead to small cavities gradually expanding down the spinal cord.
Researchers at UVA Health System found that fluoxetine, an antidepressant commonly known as Prozac, shows promise against age-related macular degeneration. Patients taking fluoxetine were less likely to develop dry AMD, a condition affecting nearly 200 million people worldwide.
Scientists develop injectable hydrogels to effectively prevent post-surgical adhesions, reducing complications and hospital costs. The hydrogel barriers demonstrate superior mechanical properties and effective prevention of cell adherence.
Scientists at Osaka University developed a novel system for targeted cancer radiation therapy using gold nanoparticles labeled with astatine-211. The nanoparticles are highly toxic to cancer cells while remaining localized, minimizing damage to healthy tissues.
The University of Missouri is developing an online certificate program for clinical engineers through a $2.6 million grant from the Missouri Department of Higher Education and Workforce Development. The program aims to increase the number of trained and qualified clinical engineers in the workforce, particularly in rural communities.
Researchers developed a quick test to identify beneficial bacteria species known to benefit coral, allowing for non-invasive assessment of coral health. The method enables rapid detection of specific bacterial species in seawater and coral samples, suggesting that the bacteria may be concentrated in coral.
New research from an international team of scientists found that poor timing of influenza vaccination campaigns in Brazil led to increased premature births, lower birth-weight babies, and the need for more cesarean sections. The study suggests that earlier flu vaccination campaigns could better protect pregnant women and their babies.
Researchers have proposed a wearable, flexible scanner to enable patients to move naturally during brain scans. The technology uses photoacoustic imaging to visualize the cerebral cortex without the need for sedation or confined spaces.
Researchers at the University of Arizona have created custom-fitted wearable devices that can monitor physiological parameters without needing recharging. The biosymbiotic devices use wireless power transfer and compact energy storage to enable continuous operation, providing accurate data on body temperature, strain, and muscle deform...
Purdue University researchers are exploring how cells defend themselves from chemical or mechanical attack and repair their damage with the help of biochemical and mechanical inputs and reactions. The goal is to develop new ways to address human health and longevity by using AI in biology.
The University of Houston is part of a $50 million NIH-funded consortium to increase AI diversity and address health inequities. The AIM-AHEAD program will bring together experts in AI, data science, and health equity research to develop more inclusive AI tools.
A novel hybrid acoustophoresis and dielectrophoresis technology has been developed for precise sorting of submicron bioparticles, including extracellular vesicles. The technology uses simultaneous acoustic and electric force fields to separate EVs with high purity and efficiency.
Researchers create a novel magnetoelastic generator that can convert human body motions into electricity, outperforming existing technology. The device is flexible, waterproof, and generates significant electrical currents, opening up new avenues for wearable and implantable diagnostic sensors.
Researchers at Texas Biomedical Research Institute developed 'reporter viruses' that allow for real-time tracking of SARS-CoV-2 spread in cells and animal models. This enables faster screening of potential anti-viral drugs, vaccines, and neutralizing antibodies.
A research team led by NJIT's Tara Alvarez is enrolling 100 participants with persistent symptoms of convergence insufficiency (CI) post-concussion for clinical trials. The study aims to establish guidelines for diagnosing and treating CI, a disabling eye disorder causing blurred vision, headaches, and cognitive difficulties.
Researchers developed a soft robotic steerable micro-catheter for precise brain surgery, enabling targeted treatment of cerebral disorders. The innovative catheter uses biomimicry to navigate and maneuver within the brain's complex anatomy.
A new machine vision system detects and quantifies radiation-induced defects in real-time, accelerating the development of nuclear components. The system uses a convolutional neural network to analyze electron microscope video frames, providing instant results on structural integrity.
A new DNA sensor can detect both the presence and infectivity of viruses in minutes, providing a significant improvement over current methods that only detect genetic material. This breakthrough could aid in tracking and containing viral outbreaks, as well as understanding mechanisms of infection.
A team of engineers and biotechnologists has developed a biosensor that measures antibiotic levels in breath, mirroring blood concentrations. This breakthrough enables on-site, personalized dosing to minimize resistant bacteria strains.
Caltech researchers have developed a technique to build embryo-like structures from human stem cells, opening up new possibilities for studying early human development. The technology can generate large quantities of these structures without the need for donated embryos.
A multidisciplinary team of Lehigh University researchers will conduct experiments on thermophoresis in complex fluids for bioseparations at the International Space Station. The team hopes to understand how temperature gradients affect particles and improve virus separation techniques with potential societal impact.
Researchers at Duke University developed an antibiotic coating that can be applied to orthopedic implants before surgery, eliminating the risk of infection. The coating, made from two polymers and an antibiotic, prevents bacterial colonization and can be personalized for individual patients.
Scientists from Hungary, Russia, and Finland created SpheroidPicker, an AI device that selects cancer cells of specific shape and size. The system enables a more standardized approach to working with tumour samples, producing a more realistic response to treatments.
Researchers from Pusan National University have compiled a comprehensive review of ginsenosides, the main component of ginseng, which can prevent inflammation, diabetes, and cancer. The study provides insights into how to improve ginsenoside production through chemical and enzymatic treatments, as well as microbial action.
A new intranasal subunit vaccine has been developed to provide durable local immunity against inhaled pathogens, addressing a significant limitation of existing vaccines. The vaccine elicits comprehensive immunity against SARS-CoV-2 within seven days and is stable for over 11 months, making it suitable for global distribution.
Researchers developed a handheld photoacoustic finder to detect cancer metastasis without radiation exposure. The device uses a solid-state dye laser and transparent ultrasound transducer to locate sentinel lymph nodes or melanoma.
Researchers developed a nanofluidic device called an 'exosome nanoporator' to load exogenous cargo into exosomes. The device efficiently loads clinically approved antitumor drugs into exosomes without damaging them, enabling the delivery of these drugs to cancer cells.