Researchers at the University of Virginia Health System have made important discoveries on the crucial role of malnutrition in global tuberculosis, highlighting how gut infections impair treatment outcomes. A new funding partnership will train Tanzanian postdoctoral researchers to work specifically on this intersection.
A family-based randomized controlled trial by University of Southern Denmark researchers found that reducing recreational screen media use increases daily physical activity in children. Children in the intervention group showed an average of 45 minutes more physical activity per day compared to those in the control group.
Scientists have found that bacterial DNA is present in the venom of snakes and spiders, which could lead to infection in victims. The study also shows that these bacteria have mutated to resist the venom, highlighting the need for clinicians to consider treating snakebite victims for infection too.
Researchers found that noisy jackdaws use a 'democratic' decision-making process to coordinate their daily takeoffs, relying on the intensity of calls to achieve consensus. The findings suggest that changes in calling intensity serve as a reliable source of information for synchronization.
A new computer-aided diagnostic tool, Deep-Lung Parenchyma-Enhancing (DLPE), uses artificial intelligence to reveal signs of pulmonary fibrosis in COVID long-haulers, helping to explain respiratory symptoms and improve disease management.
Researchers discovered that wandering salamanders, living in redwoods, have developed aerial behaviors to avoid predators, including parachuting and gliding. They are able to maintain control and make horizontal maneuvers, defying expectations of their sluggish nature.
The number of unemployed people with disabilities remained relatively steady at 590,000, while labor force participation rate showed minimal movement. Unemployment for people without disabilities has shown a slow but steady decline over the past two years.
A study by Osaka Metropolitan University researchers found ketamine boosts IGF-1, a brain molecule linked to depression. The independent pathways of IGF-1 and BDNF suggest a novel target for developing rapid-acting antidepressants.
Researchers at Princeton University developed a new pixel-by-pixel printing method that creates composite shapes, colors, and mechanical abilities using curable elastic polymers. The technique, inspired by inkjet printers, uses age-old fluid dynamics to fabricate precise and robust structures without complicated machinery.
Researchers developed photocontrolable drugs that can increase and decrease heart rate by using light of different colors, similar to approved beta-blockers. This study demonstrates the potential of photopharmacology in future therapies with reduced side effects.
A team of researchers found that jackdaws use a form of 'consensus decision-making' to decide when to leave their roosts en masse. By combining recorded calls with tests in which pre-recorded calls were played, the team discovered that birds effectively 'cast a vote' through calling out to reach a consensus.
Researchers at Boston University School of Medicine have developed a novel AI algorithm, Graph Transformer (GTP), to classify lung cancer subtypes based on whole slide images. The framework outperforms current state-of-the-art methods and has implications beyond digital pathology for computer vision applications.
Researchers at UC Riverside have found that common microbial communities can degrade a stubborn class of PFAS called fluorinated carboxylic acids (FCAs) by breaking the carbon-fluorine bond under anaerobic conditions. This breakthrough could lead to new methods for environmental remediation and reduce the harm caused by PFAS.
Researchers at Yale University have discovered a new mechanism by which some NSAIDs reduce inflammation, explaining why similar drugs produce different clinical outcomes. This discovery may inform how NSAIDs are used in the future and could lead to new applications for these painkillers.
Researchers developed a genetic test that diagnoses primary immunodeficiency disorders (PID), revealing inherited genetic defects in nearly half of patients. The test uses next-generation sequencing technology to identify specific gene variants associated with PID, enabling targeted treatment and earlier intervention for family members.
Scientists at the University of Texas at Austin have developed a low-cost gel film that can pull water from the air in dry climates, producing up to 6 liters of water per day. The film uses renewable cellulose and konjac gum, making it an affordable solution for communities struggling with water shortages.
KAUST researchers have developed a method to manufacture high-performance flexible heaters using graphene domains in nanoscale-thick graphite films. The heaters can reach temperatures of several hundred degrees within seconds when applying a small voltage, and they exhibit excellent stability and cooling rates.
Researchers at UC Davis plan to screen hundreds of compounds to discover nonhallucinogenic treatments for substance use disorders. The study aims to understand the basic mechanisms by which these compounds impact addiction and develop more effective treatments.
A large-scale study has found that men with prostate cancer have a 50% higher risk of developing serious and potentially fatal blood clots during the five years after their diagnosis. This increased risk is significant because venous thromboembolism (VTE) is a leading cause of death among people with cancer.
New research develops a low-index BaF2 thin film-based microspectrometer technology for LWIR spectral sensing. The study demonstrates the use of flat and stress-free free-standing distributed Bragg reflectors (DBRs) for high-performance wavelength discrimination in the long-wave infrared region.
A recent study published in Frontiers in Microbiology reveals the correlation between sugar identity and flexibility in SARS-CoV-2 spike glycoprotein. The researchers used high-resolution cryo-electron microscopy and computer simulation to understand the impact of glycans on antibody recognition and protein shielding.
A recent study published in JAMA Pediatrics examines the association between patient race, ethnicity, and socioeconomic disadvantage with missed telemedicine visits for pediatric patients during COVID-19. The findings suggest that these factors disproportionately contribute to higher no-show rates among disadvantaged populations.
A new study has found that a one-off treatment with senolytics can prevent premature ageing and frailty caused by cancer radiotherapies. The treatment was tested in mice and showed improved health conditions, providing new hope for cancer survivors.
Researchers at North Carolina State University have developed a new technique for extracting hydrogen gas from liquid carriers, making it faster, less expensive and more energy efficient. The new method uses sunlight and a reusable photocatalyst to release hydrogen molecules, reducing the need for rhodium and lowering production costs.
A population-scale study found COVID-19 vaccination is effective in most cancer patients but offers lower protection and wanes quickly. Vaccine effectiveness was lower (65.5%) in cancer patients compared to the general population (69.8%), with higher hospitalization and death risks despite vaccination.
The June special issue highlights the impact of structural racism on mental health and proposes community-wide interventions to address disparities. Research prioritization is also discussed to advance mental health inequity research.
Veterinarians at UC Davis have developed an AI model that can predict Leptospirosis in dogs with high accuracy, outperforming traditional testing methods. The model uses machine-learning algorithms to analyze historical data and provide timely predictions, which can be an online resource for veterinarians.
A recent study published in Nature Communications has significantly extended the understanding of one type of protein degrader technology, expanding on current validation strategies. This breakthrough could boost the number of drugs successfully entering human trials, particularly for hard-to-treat cancers.
Researchers mapped out the natural history of drywood termites, revealing oceanic voyages that accelerated their evolution and confirmed recent dispersals via humans. The study also challenged the common assumption of primitive lifestyles, highlighting the diversity and complexity of termite social behavior.
A new method called sensPIV has been developed to measure both flow and oxygen concentrations simultaneously at the smallest scales. This breakthrough allows researchers to study how corals generate flows, increasing oxygen transport, and has potential applications in life sciences, microfluidics, and medicine.
A study published in BMC Medicine found that watching less than an hour of TV per day can lower the risk of coronary heart disease by up to 16%. The research suggests that limiting TV viewing could be a useful lifestyle change for individuals with a high genetic predisposition to the condition.
Researchers found that planetary systems around binary stars form differently than those around single stars, potentially creating new targets for extraterrestrial life. The study also suggests that comets could play a key role in delivering organic molecules necessary for life.
A new statistical method for brain mapping is proposed to improve accuracy by removing redundant associations. The study uses simulations to test the method's performance on fake diseases and scores, revealing its superiority over existing approaches. The next step is to apply this refined analysis to study Alzheimer's disease.
Researchers assessed COVID-19 prevention measures in NYC public schools against the Delta variant, finding secondary attack rates and transmission patterns among students, teachers, and staff. Vaccination status played a significant role in preventing delta variant transmission.
Rice University bioengineers are developing optogenetic tools to study B. subtilis' stress response, combining experimental results with theoretical findings to understand genetic design principles. This research aims to reveal clues about bacterial survival and potentially lead to new antimicrobial drugs.
A study by researchers at UCSF found that e-cigarette use costs the US $15 billion annually in healthcare expenditures, with each user paying around $2,000 extra per year compared to non-users. The study, published in Tobacco Control, highlights the growing concern over health care costs associated with e-cigarette use.
The National Health and Aging Trends Study (NHATS) has provided insights into the trajectory of late-life functioning, accommodation needs, and consequences of disability for individuals, families, and society. The study's findings have implications for reducing disability and enhancing quality of life for older Americans.
Research published by the American Psychological Association finds that denial of structural racism is associated with anti-Black prejudice and less racial empathy. People who deny structural racism are more likely to endorse beliefs that societal inequality is acceptable and report fewer intentions to engage in social justice behaviors.
A new tool called DeepSqueak uses deep learning to identify marine mammal calls with high accuracy, even in noisy environments. The tool was originally developed for rodent ultrasound signals but has been adapted to detect sounds at other frequencies, including humpback whales and delphinids.
Researchers analyzed nearly 3.5 million patients and found no disparity in elective surgery case volume reductions among racial groups, with Black, Asian, and other non-white individuals showing similar decreases as white counterparts. The study challenges existing assumptions about the impact of COVID-19 on healthcare disparities.
Researchers discovered a previously unknown mutation in a child with epilepsy that affects the functioning of ion channels, which are crucial for brain function. The mutation has been found to decrease the function of normal proteins as well, highlighting the importance of studying genetic mutations.
A review of 38 randomized controlled trials found that counseling patients about contraceptive use and providing contraceptives increases use without increasing STI risk or reducing condom use. The interventions also decrease unintended pregnancy in trials designed to evaluate this outcome.
A global shortage of health workers poses a significant threat to effective health coverage worldwide. The study estimates that over 43 million more health workers are needed to meet targets for universal health coverage.
Researchers at Harvard John A. Paulson School of Engineering and Applied Sciences have developed a single-material diamond mirror that withstood a 10-kilowatt Navy laser without damage. The mirror's unique nanostructure design makes it 98.9% reflective, potentially enabling more robust high-power lasers for various applications.
Researchers at Aalto University have discovered a dedicated neural pathway in the retina that can detect even the dimmest shadows possible. This breakthrough could lead to unprecedented resolution in probing visual diseases.
A new study reveals that foreign fishing fleets and international seafood trade are taking fish nutrients away from malnourished populations, exacerbating nutrition insecurity. The research found that over 60% of countries receive net gains in fish-derived nutrients through international trade, while a third have net losses.
Researchers have developed gene-edited tomatoes that can produce vitamin D3 through exposure to UVB light. The tomato leaves naturally contain provitamin D3, which accumulates in the fruit after editing. This breakthrough could help millions of people with vitamin D insufficiency and provide a plant-based source of vitamin D3.
A new energy-efficient way to produce hydrogen gas from ethanol and water has been developed, enabling on-site production at fueling stations. This innovation could make clean hydrogen fuel a more viable alternative for gasoline-powered cars, reducing the need for hazardous high-pressure hydrogen gas transportation.
A UAB research team successfully monitored microplastic behavior in Drosophila larvae, revealing interactions with microbiota and intestinal barrier. The study confirms the fly's relevance as a model for studying nanoplastic effects on human health.
A new paper outlines a universal protocol for secure cryptocurrency exchanges, addressing issues of honesty, privacy, and third-party reliance. The protocol ensures honest swaps across all current and future cryptocurrencies, with no need for specialized features or high computing power.
A recent study found that nearly one-quarter of young sarcoma patients continue to use opioids after treatment is completed. The researchers highlight the need for monitoring and age-appropriate strategies to manage pain while minimizing opioid exposure.
The BiCIKL Project has successfully integrated FAIR data on biodiversity for a year, focusing on creating a more transparent and efficient research ecosystem. The project aims to link different sources of biodiversity data across various infrastructures and open data platforms.
A research team led by Professor Youdong Mao has developed a new method using time-resolved cryo-electron microscopy and machine learning-based 4D reconstruction to visualize the USP14-proteasome system in atomic detail. This reveals a 'multiverse' of parallel reality pathways, allowing for targeted inhibition of cancer cells.
A study by Thorsten Lehnert reveals that price noise from trading activities of mutual funds explains the success of 'bets against beta' strategies. These strategies, which involve taking short positions in assets with higher betas and long positions in those with lower betas, result in significant positive returns.
A recent study led by Nagoya University found that human-made iron in the Southern Ocean may be up to ten times higher than previously thought, with a 60% contribution from fossil fuel combustion. This could lead to decreased photosynthesis and increased CO2 levels, exacerbating global warming.
Researchers propose an ecological model to understand how individual responses to dietary fiber vary across gut microbiomes. The study found that specific bacteria grow in response to inulin and drive changes in gut health.
A new study reveals that ingestible sensor-enabled Truvada can identify patterns of medication taking behavior that may put individuals at risk of prophylactic failure. The system captures individual adherence patterns in real-time, allowing for tailored guidance and support.
The study investigates the nonequilibrium relaxations of hot electrons and coherent acoustic phonons in Sb2Te3 under hydrostatic pressure up to 30 GPa. It reveals a hot phonon bottleneck effect that is effectively suppressed along with the onset of electronic topological transitions.
Researchers designed two conceptual models of intelligent DNA robots that can swarm into leakless nonlinear amplification. The robots use multifunctional manipulators, trigger validators, and automatic assembly motors to amplify signals and facilitate targeted drug delivery.
Researchers found that rifampicin improved cognitive function and memory in mice with C9orf72-linked dementia. The antibiotic also reduced formation of protein aggregates, neuronal loss, and microglial activation in brain tissue. This study suggests rifampicin may be a widely effective drug for preventing neurodegenerative diseases.