A new computational method, ChIP Enrichment Analysis (ChEA), helps streamline gene expression experiment analysis and identifies potential drug targets. The database integrates results from ChIP-seq and ChIP-chip experiments, providing a better understanding of transcription factor regulation and disease development.
A recent study found that nearly half of surgeons who made over $1 million from orthopedic device companies did not have their relationship disclosed in their scientific articles. The study highlights the need for full disclosure in medical journal articles to avoid biased scientific conclusions.
Spanish researchers found that reducing emergency response time from 25 to 15 minutes can cut the risk of death by one-third. The study, based on data from the Directorate General for Traffic, suggests that faster medical responses can save lives, especially on conventional roads where deaths increase with waiting time.
A global community of environmental researchers has united to monitor and analyze Earth's carbon exchange through over 500 micrometeorological towers. The newly launched platform, Fluxdata.org, allows researchers to access and harmonize data from hundreds of sites worldwide.
The prevalence of hearing loss among US adolescents increased significantly, with 1 in 5 adolescents affected in 2005-2006. The majority of hearing loss was slight, and females were less likely to demonstrate any hearing loss.
Researchers are working to improve automatic speech recognition technology, aiming for a word-error rate of no more than 10 percent. A new multi-language audio database will be developed using publicly available sources like YouTube, featuring hundreds of speakers in English, Spanish, and Mandarin Chinese.
A study published in the FASEB Journal finds that only a few highly cited scientists hold top leadership positions at research universities. The authors suggest that a glass ceiling may exist, limiting opportunities for highly cited researchers to pursue executive management roles.
A customized medical-image database is being developed with input from dermatologists and incorporating novel eye-tracking techniques to identify critical regions in images. The project aims to bridge the semantic gap in content-based image retrieval by leveraging end-user knowledge and expertise.
A study published in Forensic Science International reveals that a person's dental patterns can be used as proof of their identity with the same degree of reliability as DNA testing. The researchers analyzed over 3,000 people and found variability values comparable to mitochondrial DNA.
Researchers at the University of Granada have created a new system for early diagnosis of Alzheimer's disease using processed images. The system achieved an impressive 90% success rate in identifying patients with Alzheimer's disease.
A global research team gathered over 600 supercentenarians, nearly 20 of whom lived beyond 115, and created the International Database on Longevity. The study reveals that many of these individuals avoided dementia until shortly before death, sparking interest in understanding the secrets behind their longevity.
A new database will gather information on technologies to assess and repair the condition of buried pipes, helping utility managers make informed decisions. The database aims to provide a single point of information for utilities to select effective and cost-effective rehabilitation technologies.
A new encryption scheme developed by Professor Nigel Smart allows for computations to be performed on encrypted data, enabling secure storage and access of sensitive information. This technology has the potential to revolutionize fields such as medical care research and electronic voting, while maintaining patient privacy.
NASA's Distress Alerting Satellite System (DASS) uses mid-Earth orbit GPS to rapidly detect and locate distress signals, greatly enhancing international rescue efforts. The system overcomes current limitations by providing continuous visibility and precision location capabilities.
A collaborative effort has resulted in a comprehensive Primate Life History Database containing life history data from long-term field studies of seven species of lemurs, monkeys, and apes. The database facilitates comparative analyses of primate evolution and ecology.
Weizmann scientists trained an electronic system to predict the pleasantness of novel odors, similar to human perception. The eNose achieved high accuracy rates, regardless of cultural background, suggesting a fundamental biological property in odorant pleasantness.
A study found that patients with sickle cell disease experience a high rate of acute care utilization, with 18- to 30-year-olds at the highest risk for rehospitalization. The analysis included data from eight states and revealed significant disparities in healthcare usage among different age groups.
The National Evolutionary Synthesis Center has released a new version of TreeBASE, a database that stores and shares phylogenetic information. The upgraded database allows for richer data storage, improved search techniques, and enhanced visualization tools.
A new database reveals that precipitation in Spain has declined in quantity in March and June, but increased in October. The study analyzed monthly precipitation series over the Iberian Peninsula between 1945 and 2005, providing a detailed image of precipitation behavior.
The study compared two chemical name dictionaries and found that automatic curation with Chemlist outperformed manual curation with ChemSpider. The Chemlist dictionary achieved a higher recall and better F-score, while ChemSpider's precision was higher after filtering and disambiguation.
Acute stroke care has improved significantly at hospitals participating in the Get With The Guidelines–Stroke program, with overall composite care improving from 72% to 93%. Hospital participation made a big impact on stroke death rates, reducing the risk-adjusted odds of in-hospital mortality by 10%.
The study examines the effects of geopolitical change on scientific production over the last 30 years. Asia's share of world scientific output grew by 155% and China has shown spectacular progress, catching up with the US in natural sciences and engineering by 2015.
Researchers found that La Vanguardia newspaper devoted more headlines to forest fires and droughts than floods, despite floods being more frequent and damaging. The study created a database of natural hazards allowing users to search for meteorological phenomena.
The MOLTO project aims to create a reliable multilingual translation tool using type theory, enabling easy extension and use by non-experts. The system will cover most EU languages, facilitating access to knowledge for all citizens.
Researchers analyzed mammal diversity data from 30 million years ago and 500 years ago, finding a significant loss of species following human arrival in North America. The study suggests humans are causing another mass extinction event, with potential conservation efforts able to stem the tide.
The Eukaryotic Pathogen Genome Database Resource has been expanded with a new contract to support worldwide research into human pathogens. The database provides tools for identifying vaccine antigens and drug targets, facilitating the search for effective diagnostics.
A new study found that opioid-related deaths in Ontario, Canada have doubled since 1991, with a significant increase in oxycodone-related deaths. Most of these additional deaths were accidental, and the study suggests that increased rates of opioid prescriptions are a major factor in these deaths.
Researchers Arnie Miller and Michael Foote analyzed fossil data from epicontinental seas and open-ocean-facing coastlines during three 'Big Five' mass extinction events. They found higher extinction rates in open-ocean settings, indicating these environments were more susceptible to mass-extinction-causing agents.
Researchers found that key employee migration reduces an organization's competitive advantage, even in superior organizations with established routines. The loss of strategic knowledge through employee migration allows rival firms to develop competitive responses.
Researchers at the University of Pittsburgh are leading a $9 million, five-year initiative to study the cause of facial birth defects. They will create an encyclopedic database of how faces develop and what goes wrong to cause malformations.
Scientists have assembled the largest-ever collection of liver proteins, which could become a roadmap for finding new biomarkers and treatments for liver disease, including hepatitis. The database includes 6,788 non-redundant proteins, many of which are related to diseases in the nervous system.
Experts from 11 countries agree on a joint DNA-based database to combat child trafficking, with the goal of eradicating the crime. The DNA-Prokids Programme aims to reunite victims with their families and prevent further exploitation.
The world's top experts in endangered languages are converging at the University of Utah to create a comprehensive online database. The gathering aims to preserve 7,000 languages that are at risk of extinction, with nearly 90% predicted to disappear in the next 100 years.
According to the World Database of Happiness, Spain holds the 16th position in terms of happy years of life, with a score of 58.8 years. This ranking is based on an indicator developed by the Erasmus University of Rotterdam, which combines life expectancy and happiness averages.
The National Institute of Allergy and Infectious Diseases has awarded a $15.7 million contract to develop an open-access national online database and analysis resource center for viral pathogens. The database will contain information on viruses such as herpes, hepatitis C, and smallpox, as well as newly emerging pathogenic viruses.
Researchers have developed a reliable way for doctors to filter MEDLINE for relevant kidney patient information, improving treatment and outcomes. The new tool has high performance, exceeding 97% sensitivity and specificity, making it available for all healthcare professionals.
Researchers propose six categories to describe genome sequence quality, from 'Standard draft' to 'Finished', addressing concerns over data integrity and reliability. The new standards aim to standardize sequencing technologies and help researchers know the quality of publicly available genomes.
The NIDCR launched the FaceBase Consortium to systematically compile biological instructions for constructing the middle region of the human face and define genetics underlying developmental disorders. A comprehensive database will be created to enable scientists to mine information and accelerate research.
The new NIST database on gas hydrates provides a comprehensive collection of data on the properties of these naturally occurring crystalline materials, which are a potential energy resource and may affect the Earth's climate. The database contains over 12,000 individual data points for 150 compounds and 400 different chemical systems.
The GRACE registry study analyzed 43,018 ACS patients to determine the optimal revascularisation strategy for unprotected left main coronary disease. PCI is now the most common revascularisation strategy, preferred in higher-risk patients, while CABG is often delayed and associated with the best 6-month survival.
A Rutgers University—Camden biochemist is creating a database for quick background checks on all known enzyme functions, including energy-creators like ATP and ADP. The goal is to create a standard vocabulary to describe how enzymes function for the biomedical community.
Researchers developed a neural network system to classify music genres, such as cha-cha-cha, jive, and tango, with varying degrees of success. The approach combines the strengths of two existing methods and uses a neural network to analyze beat and tempo, outperforming other classification techniques.
Engineering programs retain students equally to other majors, and women are just as likely to stick around as their male counterparts. However, a narrow path exists for students to migrate into engineering from other majors, highlighting the need for institutions to adopt universal prerequisites.
A new comprehensive health care database, DARTNet, aims to advance medical research and improve patient care by facilitating secure data sharing among clinicians and organizations. The database, part of a national health data network, has the potential to transform the quality of healthcare by enabling high-quality observational studies.
A study published in the Journal of the National Cancer Institute found women with hormone receptor-negative first tumors have twice the risk of developing a second breast cancer compared to those with HR-positive tumors. The research also identified a five-fold increase in risk of a second hormone-receptor negative breast cancer.
Researchers found that patients with elevated serum creatinine, on life support, and children under 18 whose liver failure was caused by antiepileptics had poorer outcomes. A prognostic model developed by the study showed strong predictive ability for survival after transplantation.
The Gene Expression Atlas collates data from over 1000 studies, providing insights into gene function and development of new drugs. The resource allows users to query gene expression under various conditions, enabling researchers to identify key genes in specific diseases.
The Immune Epitope Database and Analysis Resource (IEDB) is the world's largest collection of scientific data on how the immune system responds to infectious diseases. With its 2.0 launch, researchers worldwide can now easily access and analyze over 95% of published information on immune epitope responses.
A new study published in The Journal of Bone and Joint Surgery found a strong link between genetic predisposition and rotator cuff tears. Family members of patients with rotator cuff tears are at increased risk of similar tendon tears, suggesting that heredity plays a role in the development of the disease.
Scientists use DNA barcoding to identify mosquito species spreading lymphatic filariasis, a disease causing permanent disability worldwide. The technique reveals menace species habitats and range, aiding understanding of environmental factors influencing their breeding.
The Protected Areas Database – United States (PAD-US) is a national inventory of protected lands in the US. The database contains information on over 22,000 highly protected areas, covering 15% of the country's land area.
The DECIPHER database has revealed its developing role in revolutionizing both clinical practice and genetic research, providing a key to unlock the causes of illnesses. The data from around 100 centres has been shared openly worldwide, benefiting researchers, clinicians, and patients.
The Journal of Correctional Health Care has been accepted into the premier bibliographic database MEDLINE, making its research and case studies more accessible to a vast audience. The journal, published by SAGE on behalf of NCCHC, addresses correctional health care topics through original research, best practices, and literature reviews.
The Deep Sky project develops a user-friendly database system and interface to serve high-resolution cosmic reference images to astronomers worldwide. This enables instant access to processed observations for analysis, facilitating research in various scientific disciplines.
The University of Oregon's GEMs database has doubled in size, now featuring over 100 items on green chemistry strategies across various disciplines. The database allows educators to search by concept and contribute to threaded discussions, capturing the iterative process of greening laboratory activities.
A new decade-long database of aerosol measurements over land has been compiled, revealing a global decline in clear sky visibility from 1973 to 2007. This trend is indicative of increases in airborne pollution and its impact on climate change research.
The Comprehensive Dialysis Study (CDS) includes data on more than 1,600 patients, providing a valuable new resource for improving dialysis outcomes. Researchers can examine the interrelated factors affecting the health of new dialysis patients and identify predictive significance of early physical and nutritional status.
A study found that about 64% of US hospitals did not give tissue plasminogen activator (tPA) to Medicare patients between 2005 and 2007. The researchers also discovered that 40% of the US population resides in a county without a hospital that provides tPA treatment.
A database detailing life history traits of over 4,000 animal species has been developed for studying ageing, evolution, and conservation. The AnAge resource provides insights into the mechanisms of ageing and how environmental adaptations influence lifespan, with potential applications in conservation efforts.
Researchers used electronic medical records to evaluate drug therapies, finding results comparable to randomized clinical trials in nine out of 17 outcomes. The study suggests enormous amounts of information within EMR databases can expand healthcare knowledge.