Articles tagged with Covid 19 Vaccines
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A recent study in JAMA Network Open explores COVID-19 vaccine refusal and willingness, highlighting trust in health authorities as a crucial factor. The research suggests that building trust in healthcare professionals, experts, and public health agencies is essential for overcoming pandemic-related vaccine hesitancy.
A study by UC Riverside researchers found that communities of color in Inland Southern California experienced fear and mistrust of institutions due to historical, cultural, and social traumas. The study highlights the need for culturally sensitive health interventions to address these traumas and promote community-based approaches for ...
Researchers at Duke University Medical Center have developed a single nanoparticle vaccine that protects against SARS-CoV-1 and MERS coronaviruses in addition to SARS-CoV-2.
A primary mRNA vaccine series offers significant protection against SARS-CoV-2 infection in Singaporean children aged 1-4. The study found a low incidence of hospitalization and severe illness, but highlights the potential benefits of vaccination in preventing infection and sequelae.
Research found that young children's immune systems produce protective antibodies at high levels for up to 300 days after infection. Unlike adults, children have high levels of inflammatory cytokines in their noses but not in their blood, potentially explaining the mildness of COVID-19 in this age group.
A new AI tool named EVEscape can predict future viral variants of concern, potentially helping scientists develop more effective vaccines and therapies. The tool uses evolutionary and biological information to forecast which mutations will occur in viruses like SARS-CoV-2.
A recent study published in the Journal of Clinical Investigation found that coronavirus vaccines build immune memory in various organs, including the liver, kidneys, and lungs. This local immune response is more effective than circulating antibodies in protecting against infection.
Researchers found a quantitative difference in B cell response following vaccination between young and older adults, with younger adults mounting a stronger clonal response and older adults having more activated B cells. This study provides insights into the age-related differences in B cell vaccine response and may lead to the develop...
A study by National Jewish Health found that nearly half of patients with underlying lung conditions have lower vaccine-specific antibody, B cell, and T cell responses compared to healthy individuals. This decreased immunity suggests patients with lung conditions may be less protected against COVID-19.
A Singaporean study found that unvaccinated COVID-19 survivors are at a heightened risk of heart complications almost a year after recovery. The study revealed a 56% higher risk of developing new heart complications among unvaccinated survivors compared to uninfected individuals.
A new study reveals that immunity to SARS-CoV-2 variants depends on previous exposure and vaccination history. The research found significant differences in immune responses to various variants, highlighting the need for personalized vaccine approaches.
Research published in European Journal of Neurology indicates that COVID-19 and COVID-19 vaccination have negligible effects on migraine severity. Among participants who reported worsening migraines, those infected were 2.5-times more likely to be concerned about migraine worsening than those vaccinated.
Researchers found that antigen testing significantly reduces the probability of cluster occurrence by identifying and isolating infected persons. However, it may not be effective against highly infectious mutant strains like Omicron, highlighting the need for booster vaccination campaigns and other infection control measures.
Researchers developed a new base modification, Z-mRNA, that demonstrates low immunogenicity and reduced cytotoxicity compared to unmodified mRNAs. The modified mRNA can induce a substantial immune response and has potential therapeutic applications beyond COVID-19 vaccines.
Researchers found that using electronic prompts during appointment scheduling for seasonal flu and COVID-19 vaccines can identify willing participants for HPV and shingles vaccines. Only 30% of those booking for these vaccines were already vaccinated against HPV, presenting a significant opportunity for targeted campaigns.
A new study found that nearly 40% of eligible adults did not receive a COVID-19 booster due to prior infection with SARS-CoV-2 or concerns about vaccine side effects. The researchers hope the findings can inform design of interventions to improve vaccination rates.
Scientists have developed a trivalent vaccine candidate that provides broad and long-lasting protection against COVID-19 infection by delivering the vaccine via the nose. The vaccine triggers a strong neutralizing antibody response and protects mucosal areas, preventing disease symptoms.
The article discusses the need to reassess COVID-19 precautions in 2023, particularly for patients with hematologic malignancies. The researchers highlight the increased risk of poor response to vaccination and worse outcomes from COVID-19 infection among these patients.
Researchers identified two SARS-CoV-2 protein mutations linked to severe COVID-19 symptoms and increased inflammation. The mutations, known as KR, were found in patients with higher viral loads and more severe symptoms.
A new vaccine candidate has shown protection against a range of coronaviruses, including current and future variants, by targeting the critical regions of the virus that it needs to complete its life cycle. The vaccine technology, developed at the University of Cambridge, aims to provide broad-based protection against emerging viruses.
Pregnant women are urged to get vaccinated against COVID-19 to protect themselves and their babies. A new study suggests that COVID-19 vaccines and boosters can significantly improve maternal-fetal outcomes.
A study of 68,000 patients with COVID-19 found that using Paxlovid or Lagevrio significantly reduced mortality and hospitalization rates in those at high risk of progressing to severe COVID-19, regardless of age, race, or virus strain. These medications can be used to treat non-hospitalized patients at high risk of severe disease.
Researchers at Cleveland Clinic have developed a potential vaccine candidate against Dabie Bandavirus using nanoparticles, which can deliver antigens at a lower dose with fewer side effects. The vaccine has shown promise in pre-clinical studies and could provide protection to adults over 50, who are most vulnerable to the virus.
A study has identified key T cell subsets that track closely with successful vaccination and are responsible for early protection against SARS-CoV-2. The research found distinct CD8+ T cells that proliferate and attack key proteins of the pandemic virus, particularly those lacking surface protein KLRG1.
The American Thoracic Society has partnered with five new health systems to identify barriers to vaccination and find ways to improve immunization rates. The initiative aims to increase COVID-19, flu, and pneumonia vaccine uptake among high-risk adults with respiratory diseases.
The American College of Physicians has issued updated rapid, living practice points on treating COVID-19 patients in outpatient settings. The new guidance supports the use of molnupiravir or nirmatrelvir-ritonavir for symptomatic patients with confirmed mild to moderate COVID-19.
A large-scale study analyzing data from 197 million people has generated background incidence rates on conditions such as myocarditis, pulmonary embolism, and Guillain-Barré syndrome for COVID-19 vaccine safety monitoring. The findings provide important data for investigating reports of medical events following vaccination.
Researchers at George Washington University found that Facebook's core design features undermine its policies aimed at removing Covid-19 vaccine misinformation. The platform's architecture, designed to build communities around shared interests, can inadvertently facilitate the spread of misinformation.
A study by researchers at the University of Illinois Urbana-Champaign found that YouTube's recommendation system did not promote anti-vaccine content during the COVID-19 pandemic. The study analyzed over 27,000 video recommendations and found that users were directed to longer, more popular health-related content.
Receiving two doses of BNT162b2 vaccine was associated with lower risk of COVID-19 emergency department and outpatient visits. The risk appeared lower for those with two versus three doses, despite Omicron sublineages becoming dominant.
A recent study published in the International Journal of Infectious Diseases found that individuals infected with the Omicron variant have a significantly lower risk of developing long COVID compared to those infected with earlier variants. The study analyzed data from over 11,000 people and found that around half of all wild-type infe...
The Mount Sinai Hospital received a $13 million NIH grant to create vaccines that can protect against various types of coronaviruses. The project aims to develop variant-proof, universal vaccines that offer broad protection against existing and future SARS-CoV-2 variants, pandemic, zoonotic, and seasonal coronaviruses.
A multi-state study confirmed that COVID-19 mRNA vaccination protects babies and young children against COVID-19-associated emergency department/urgent care visits. The study found that even one dose of the two-dose vaccine series provided some protection for this age group.
A study of 50,000 COVID-19 cases found that immunity following infection provides better protection against transmission than vaccination, but only for a short period. Vaccination reduces contagiousness over a longer time, making it essential to consider simple public health measures like air filtration and mask-wearing.
A study of health care workers found that co-administering COVID-19 and influenza vaccines was not associated with reduced immune response or increased adverse events. The results support the co-administration of these vaccines, suggesting a safer and more efficient vaccination strategy.
A new editorial paper explores the effectiveness of the third dose booster vaccine against SARS-CoV-2 in immunocompromised individuals. Researchers found that while the vaccine improves vaccine effectiveness across various measures, its benefits are not as significant for patients with cancer.
The new approach boosts immunity by engineering nanoparticles and antigens to stimulate a stronger immune response. The vaccine induces a strong immune response when delivered intranasally, potentially leading to longer-lasting immunity and reduced costs.
In a cohort study of 2,055 patients with glomerular diseases, COVID-19 vaccination did not worsen kidney damage or affect proteinuria. The data support vaccination for COVID-19 in patients with glomerular disease.
A recent study found that ChatGPT scored 9/10 in accuracy for debunking Covid-19 vaccine myths, making it a reliable source of non-technical information. The AI tool's responses were accurate in addressing both true and false contraindications, but highlighted potential concerns over changes in answers over time.
A new study found that nearly half of dog owners in the US hold negative views about vaccinating their pets, citing safety and efficacy concerns. This hesitancy is linked to public mistrust in human vaccines during the pandemic, posing serious public health implications for both animals and humans.
A DNA-based vaccine has shown promise in a preclinical study by Scancell Ltd and Texas Biomedical Research Institute. The vaccine prompted a robust immune response, including T cell activation and antibody production.
Two studies published by Aarhus University found that common side effects like malaise, fever, and fatigue occur frequently after COVID-19 vaccination. Menstruating women reported a 30% increase in menstrual cycle changes, with stress, age, and smoking contributing to the correlation.
The CDI published a study tracking nasal swabs of thousands of patients in New Jersey, providing new insights into the pandemic's peak. The results highlight the importance of vaccination, reinforcing the positive impact of COVID-19 vaccination and public health benefits of genotypic surveillance.
Researchers have identified a key protein in SARS-CoV-2 that, when targeted, elicits a robust immune response. A live-attenuated vaccine based on this protein shows promise in preventing disease and offering long-lasting immunity. The approach could target areas of the genome less likely to change with variants.
Researchers are developing a community-based digital health intervention to increase vaccination uptake among children in rural and underserved areas. The project aims to empower community health workers to deliver education on vaccinations, overcoming the digital divide and addressing challenges faced by limited health workforce.
A new essay highlights how news stories about healthcare workers during COVID-19 often left out crucial socioeconomic and environmental contexts, which can impact consumer thoughts and responses. By introducing a public health framework, experts aim to broaden storytelling and reframed scientific information dissemination.
Mayo Clinic researchers found that vaccinated patients with long-haul COVID were less likely to experience symptoms such as abdominal pain, chest pain, and shortness of breath. The study involved 477 patients who sought treatment for long-haul COVID at Mayo Clinic between May 27, 2021 and July 26, 2022.
Research identifies immunosuppressed individuals with lower antibody prevalence after three or more COVID-19 vaccine doses, highlighting increased vulnerability to severe infection. The MELODY study found that around one in five people with compromised immune systems had no COVID-19 antibodies.
Researchers tracked infections among Connecticut correctional facility residents to find that high exposure to the virus reduces vaccination and prior infection effectiveness. Hybrid immunity provides higher protection in such settings.
A Murdoch Children's Research Institute-led review found COVID-19 vaccines are effective against severe cases of the disease in children and adolescents. However, with most children now having caught the SARS-CoV-2 virus and building up a natural immunity, the additional benefit of vaccination in healthy children is minimal. The review...
A long-term study of nearly 2,400 solid organ transplant recipients found that COVID-19 vaccination significantly reduced hospitalization rates, with a 75% decrease in later omicron waves. Despite this, post-vaccination SARS-CoV-2 viral infections remain common, highlighting the importance of vaccination in high-risk populations.
Researchers developed a new method to assess immune responses to specific antigens after mRNA SARS-CoV-2 vaccine administration, using B cell receptor repertoire analysis. This approach enables evaluation of post-vaccination responses in immunocompromised patients with high antibody titers.
A new study found that around one in five people with compromised immune systems have no COVID-19 antibodies after three or more vaccinations. The MELODY study identified specific groups at higher risk of not producing antibodies, highlighting the need for targeted interventions and booster vaccines.
Scientists have discovered that SARS-CoV-2 can infect cells using multiple entry points beyond ACE2, explaining its ability to jump between species. This finding highlights the need for continued monitoring of coronaviruses and their potential to cause future pandemics.
Researchers found that sequential vaccinations given in the same arm generated a stronger immune response than those administered in different arms. This is particularly true for cytotoxic CD8+ T cells and antibodies targeting the SARS-CoV-2 virus.
Researchers found that COVID-19 vaccination generates antibodies in pregnant people that cross the placenta and protect their newborns against severe COVID-19 disease. Booster doses also increase maternal and newborn immune defenses against COVID-19, supporting the use of vaccination during pregnancy.
Recent studies have found no link between COVID-19 vaccination and sudden cardiac arrest in athletes. However, a small decrease in VO2 Max has been observed after vaccination, which may be temporary and have minimal clinical relevance.
A third COVID-19 vaccination dose significantly improved antibody responses in transplant recipients, offering better protection against variants. However, cross-protection was only partial, highlighting the need for multiple vaccine doses to maintain immunity in this vulnerable population.
Pregnant individuals who received a full course of COVID-19 vaccination and a booster have the strongest immune protection from the disease. Boosting after previous infection increases antibody levels in both mothers and newborns, providing maximum possible protection to infants as SARS-CoV-2 evolves.
A new Northwestern Medicine study measures resilience in biomedical scientists during COVID-19, revealing that resiliency did not guarantee career advancement. The study found that women scientists faced greater household responsibilities and social pressure to advance their careers, leading to significant career setbacks.