Research on the tests that detect and monitor disease. Covers blood tests, cancer monitoring, emergency diagnostics, and new patent-pending assays.
A Stanford University School of Medicine study found that napping improved mood, alertness and performance in doctors and nurses who worked night shifts. The study's results showed that a short nap break reduced fatigue, sleepiness and performance lapses.
Researchers developed a simple, noninvasive test to measure right ventricular function and predict survival of adults with pulmonary hypertension. The test, TAPSE, assesses echocardiographic abnormalities in the tricuspid valve and showed that patients with advanced right ventricular dysfunction had dramatically reduced survival rates.
A study analyzing hair samples from over 8,000 individuals found that babies can be exposed to crystal meth in the womb, with wide-ranging levels detected in both mothers' and newborns' hair. The findings suggest restricted fetal growth and developmental problems, highlighting the need for increased awareness and safety measures.
A team of researchers has developed a model that tests Pe-ter Richardson's long-held hypothesis about the formation of blood clots. The model, which uses high-speed computing, reproduces several odd features of thrombus growth observed in laboratory experiments and tissue pathologies.
The study found that virtual colonoscopy can detect polyps and cancers, but also reveals findings outside the colon that require additional testing, adding significant costs
Analyzing carbon and nitrogen in hair strands can determine whether a person has an eating disorder, providing an objective measure for diagnosis. The test required only five strands of hair to predict with 80% accuracy whether a person had anorexia or bulimia.
A study by human factors/ergonomics researchers found that virtual reality-based simulators can effectively train military medical personnel in high-stress conditions. The simulation tested the efficiency and quality of emergency chest tube thoracostomy procedures, revealing a correlation between faster completion times and poorer work...
Researchers at Cedars-Sinai Medical Center found that a nonabsorbable antibiotic can effectively treat irritable bowel syndrome (IBS) even after treatment ends. The study showed sustained benefits for participants who received rifaximin, providing new hope for those suffering from IBS.
Menzies School of Health Research has received $4.6 million in funding from the National Health and Medical Research Council to boost its research capability in Indigenous, remote, and tropical health. The funding will support six projects, including the Aboriginal Birth Cohort Study and scabies diagnosis development.
A pioneering study has found that people with lower or declining cognitive ability are at greater risk of falling. The research, which followed over 500 participants aged 70 over eight years, identified women and multiple fallers as being more likely to experience falls.
Researchers at The University of Manchester are developing new techniques using cultured human cells to identify carcinogens and reduce the need for animal testing. The project aims to increase confidence in pre-animal tests and minimize false positives.
Researchers have developed a new, simple, and rapid tuberculosis (TB) test called microscopic-observation drug-susceptibility (MODS). The test takes an average of seven days to complete and is more sensitive, faster, and cheaper than current culture-based tests.
Researchers at the University of Virginia are developing an office-based cancer screening test using biomarkers in urine to detect early signs of cancer. The goal is to improve detection and treatment outcomes, as current tests often rely on invasive procedures or delayed diagnoses.
A study of 2,223 healthy men and women found that those with high body mass index (BMI) scores performed worse on cognitive tests than those with low BMI scores. The study suggests a possible link between obesity and cognitive decline in middle-aged adults.
Researchers have made significant advances in optics tests for early Alzheimer's detection, which may enable universal screening technologies. The tests can identify small molecular signs of the disease in the eye before brain pathology is present, raising hopes for early diagnosis and slowing disease progression.
Government laboratories can quickly analyze radioactive samples but with variable accuracy and quality control procedures. The NIST tests found that measurement capability is generally accurate within 30% of the expected value.
A University of Alberta study found that walking alone is unlikely to produce marked health benefits compared to more intense exercise programs. Regular moderate activity and occasional vigorous periods are crucial for optimal health outcomes.
Physiologic Communications is developing an implantable biosensor that can detect physiologic and chemical changes with faster accuracy than current methods. This 'living chip' has the potential to revolutionize disease monitoring by providing real-time data to physicians and enabling timely interventions.
A new study found that IPF patients who can cover less than 680 feet during the six-minute walk test are four times more likely to die. The test's accuracy was found to be superior to other measures, such as forced vital capacity percent (FVC%).
Researchers have developed two new technologies to measure cell growth in the laboratory, one for monitoring drug effects on cancer cells and another for testing multiple cell types or dosages simultaneously. This breakthrough could lead to more accurate assessments of cancer treatments and improved drug development.
The Mayo Clinic has discovered an asthma diagnostic test that can accurately predict a patient's response to inhaled corticosteroids for chronic cough. The exhaled nitric oxide test measures inflammation in the lungs' bronchial tubes, showing promise as a more accurate and efficient alternative to methacholine challenge testing.
A study of 124 women found that hormone-replacement therapy with progestin resulted in a 10-30% increase in hearing loss compared to estrogen-only or non-HRT groups. Women on progestin showed signs of damage in both the inner ear and brain used for hearing.
Researchers developed a new, simple, and accurate dipstick test to identify the cause of bacterial meningitis outbreaks in Africa. The test uses patient spinal fluid and can determine the presence of four common meningococcus groups, paving the way for targeted treatment decisions.
Researchers found that nicotine withdrawal symptoms begin as early as 30 minutes after quitting, impacting smokers' cravings, mood, and behavior. This discovery challenges the common assumption that withdrawal symptoms occur later in the process.
Blood alcohol levels above legal limits increased significantly among emergency care patients, with a 113% rise in lab tests from 1999 to 2004. The number of intoxicated women doubled, while men consistently outnumbered women across all age groups.
A new kidney test, cystatin C, has been found to accurately predict higher risk of chronic kidney disease, cardiovascular disease, and death among elderly people. The study, published in Annals of Internal Medicine, suggests that a normal creatinine level should not reassure patients of normal kidney function.
A new study published in Vaccine found that a recombinant Protective Antigen (PA) protein vaccine produced the desired immune response in healthy adults, justifying further testing. The investigational vaccine demonstrated a clear relationship between the amount of vaccine administered and the subsequent immune response.
Researchers at Indiana University are working on a project to craft messages that encourage women to be tested for HIV and enroll in research clinical studies. The study aims to identify barriers to testing and develop persuasive messages to overcome them.
A four-year study found chronically high blood sugar associated with increased risk of mild cognitive impairment (MCI) or dementia. Women with elevated glycosylated hemoglobin were four times more likely to develop MCI or dementia than those with lower levels.
Researchers found great apes outperforming monkeys and lemurs in problem-solving tests across multiple paradigms. This suggests a broad, domain-general type of intelligence that allows them to succeed in various situations, contradicting the theory of specialized skills.
Researchers have adapted a psychiatric test for monitoring mental abnormalities in mice, revealing a key skill impaired in humans with autism and similar illnesses. The study found that mice can learn to switch attention between tasks, shedding light on the cognitive deficits underlying human mental dysfunction.
A new laboratory test can help determine whether patients with a history of venous blood clot are at low risk of developing another blood clot. Patients with low thrombin generation levels, measured by the commercially available test, have a low risk of recurrence, with an estimated 7% likelihood after 4 years.
Hopkins researchers have created a biosensor that allows them to see multiple, real-time chemical reactions in living cells. The sensor can locate where an enzyme is being turned on or off within the cell, providing valuable insights into how chemicals interact with enzymes.
The new non-invasive test allows for fetal sex determination at 5-7 weeks of gestation, sparking debates about the technology's implications. Experts warn that rapid policymaking is needed to address ethical concerns surrounding its use, particularly in cases where abortion is considered.
Researchers have developed a digital magnetofluidics method that enables precise analysis of biological fluids using nanoscale surface patterns. This technology holds promise for improving medical diagnoses, environmental safety, and public security by reducing testing time and costs.
A cross-sectional study of 1,268 adults in Botswana found that routine HIV testing is widely accepted and may reduce barriers to testing. The authors emphasize the importance of informed consent and human rights safeguards to protect individuals from discrimination and violence related to testing.
Quitting smoking significantly improves lung function test scores in asthmatics, even after just one week of no cigarettes. The study found a notable increase in lung function improvements compared to high-dose anti-inflammatory treatment.
Researchers developed a non-invasive Doppler ultrasonography method to detect fetal anemia in high-risk pregnancies. The study found that this new procedure is safer than traditional testing methods, which can be traumatic for the mother and carry a risk of miscarriage.
A study led by Associate Professor Barbara Fazekas de St. Groth found that healthy individuals have up to twice the number of disease-fighting regulatory T cells compared to IBD patients. This discovery has significant implications for diagnosing and preventing autoimmune diseases.
Researchers at the University of Texas Medical Branch have developed a potential test to estimate how many people are infected with variant Creutzfeldt-Jakob disease (vCJD), which can take up to 40 years to manifest. The test could also help prevent transmission through blood transfusions and organ transplants by detecting prions in th...
Particles of toxic lead solder used in plumbing can evade detection in some water quality tests, according to researchers funded by the National Science Foundation. Larger particles can get trapped in faucet aerator screens, while smaller particles stick to sampling containers, resulting in inaccurate readings.
A simple and inexpensive test identifies tumours with protein IMP3, predicting cancer spread, allowing for targeted treatment. Patients with these tumours are six times more likely to develop metastasis and four times more likely to die after surgery.
Researchers developed a safe way to monitor amyloid beta peptide production and clearance rates in the human central nervous system. This test could improve diagnosis and treatment of Alzheimer's disease, as well as help scientists better understand its causes.
Researchers found that people tend to consume a single unit of food when served in a small portion, despite the actual quantity being larger. This 'unit bias' helps explain how environmental factors influence eating habits and may contribute to obesity.
A survey of UK laboratories showed a 83% increase in lab test requests from primary care between 2000 and 2004. Two strategies developed by Dr. Bernie Croal reduced unnecessary test requests by 10-22% in Scottish primary care practices. These interventions are feasible within most laboratory settings.
William H. Herman suggests that glycosylated hemoglobin test may not be suitable for making diabetes diagnosis, and instead recommends blood glucose tests after a special sugary drink for accurate diagnosis. Population-level studies show how screening can optimize detection of impaired glucose tolerance and prevent diabetes complications.
A study of nearly 600 female heart failure patients revealed that women had better outcomes with lower VO2 levels and less need for a heart transplant. The results challenge the current 'gold standard' for assessing treatment options, highlighting the importance of considering gender differences in heart failure management.
Research suggests that moderate alcohol consumption is associated with better mental performance and reduced risk of dementia in older women. Women who reported drinking up to two or three drinks per day performed better on measures of global cognitive function, particularly in verbal skills.
Studies conducted by Harvard researchers reveal that prosopagnosia, or 'face-blindness,' may be more common than previously thought, affecting up to 2% of the general public. The condition can lead to social isolation and difficulty recognizing familiar faces, prompting individuals to rely on non-facial traits for recognition.
A UCLA/VA study found that many eligible VA patients with abnormal FOBT results did not receive follow-up diagnostic tests such as colonoscopies or barium enemas. The study identified factors contributing to lack of follow-up, including lack of primary care visits and delayed referrals.
A recent study found that patients with genital HSV-2 infection who knew they had the virus and informed their partners were about half as likely to transmit the virus. The study suggests testing and disclosure as effective tools to prevent HSV-2 transmission, along with suppressive antiviral therapy and condom use.
A European-funded project aims to create a predictive diagnostic test for early detection of kidney loss and target effective therapies. Researchers will utilize nanobead technology and multiplexing platform to identify biomarkers in diabetic urine, enabling early identification of patients at risk.
Pre-diabetes and undiagnosed type 2 diabetes affect millions, increasing heart disease risk. Research shows nearly 22% of people aged 65+ have diabetes, with significant disparities among ethnic groups.
A University of California, Berkeley study found that certain household products emit toxic compounds when used indoors, exceeding regulatory guidelines. The research measured pollutants from cleaning agents and air fresheners under typical indoor use conditions, highlighting the need to address chronic exposure to these substances.
A neurocognitive study found that mixed amphetamine salts extended release improved divided attention, visuospatial working memory, visual scanning, and mental flexibility in adults with ADHD. Participants who received the medication showed significant improvements in response speed and maintained accuracy when switched to placebo.
A long-term study of over 44,000 women found that Chlamydia testing increased the risk of severe reproductive complications, but at lower rates than previously thought. The study suggests that current screening programs may not be as effective as assumed, raising questions about their cost-effectiveness.
A new study found that Enablex, a prescription medication for overactive bladder (OAB), did not cause significant memory impairment in healthy adults aged 60 and older. In contrast, the alternative treatment Ditropan XL caused noticeable memory deterioration, despite the patients being unaware of this change.
Research links lower physical performance scores to higher risk of dementia, including Alzheimer's disease, in older adults. Those with better physical function tend to have slower cognitive decline and lower risk of developing dementia.
A novel stool testing technique has been developed, showing high sensitivity (88%) in detecting colon cancer. The new test is more sensitive than previous versions, making it easier to perform and potentially leading to better patient outcomes.
Researchers developed a simple clinical rule to predict patients at high risk for subarachnoid hemorrhage (SAH), reducing investigation rate to 66%. The rule uses 4 simple observations, including vomiting, diastolic blood pressure, and age, to identify patients who require further investigation via CT and/or LP.