Articles tagged with Translational Research
Mount Sinai joins a nationwide network of medical centers specializing in rare disorders to foster knowledge-sharing, connect patients with specialists, and improve treatment and research. The designation aims to establish a standard of care for rare diseases.
A group of researchers led by Indiana University School of Medicine's Benjamin Gaston will receive a research program project grant to fund the development of personalized therapeutic approaches for severe asthma. The grant will support three key projects focused on S-nitrosylation signaling, airway pH regulation, and androgen signaling.
The American Geriatrics Society will create a national self-directed learning curriculum to support researchers studying multiple chronic conditions, with a focus on resilience. The organization will also host a series of prestigious scientific conferences exploring emerging issues in aging research.
The university will support research on normal and abnormal brain development, including rare diseases that cause intellectual disabilities. Researchers aim to improve care and treatment for children with IDDs.
Lehigh University will lead a five-year, $25 million research collaboration to develop new semiconductor materials and scalable manufacturing processes for advanced optoelectronic devices. The initiative aims to transform fields like information technology with quantum technologies.
The University of Kentucky Center for Clinical and Translational Science has received a $23.5 million award to support groundbreaking health care innovations in Kentucky. The center has successfully catalyzed clinical and translational discoveries, including COVID-19 vaccine trials, with continuous funding since 2011.
Researchers at MUSC identify a type of fat called sphingolipid that could predict the severity of heart disease in African American patients with lupus. Higher levels of Lac-Cer are associated with increased disease activity and may have predictive value for patient progression.
Researchers predict two nicotine biomarkers, NMR and TNE, in smokers of multiple ethnicities using machine learning approaches. These models can estimate nicotine biomarker levels from DNA data or existing genomic information.
A digital oral health approach aims to improve healthy behavior, lower risk factors, and reduce oral health inequalities. The use of digital tools has demonstrated potential in expanding oral healthcare access worldwide.
The UC Davis Clinical Translational Science Center has been awarded a $33 million grant renewal from the National Institutes of Health (NIH) for a five-year period. The center will continue to provide critical funding and essential services to advance outstanding research in human health, with a focus on reducing health disparities.
The TL1 program requires students to shadow physicians treating patients with diseases at the center of their research, bridging basic science and clinical cultures. This rotation provides a two-way street of education, where students learn about patient problems and bring basic science questions to address them.
The Altman Clinical and Translational Research Institute at UC San Diego has received a five-year, $54.7 million Clinical and Translational Science Award from the National Institutes of Health. This grant will refine fundamental work and provide new resources to launch a wave of discovery and transformation.
The COVID-19 pandemic highlights the need for better dental care and oral health strategies. Research suggests that SARS-CoV-2 is primarily transmitted through direct contact and respiratory droplets, with oral mucosa being an initial site of entry.
The SCTR Institute, a Clinical and Translational Award (CTSA) hub, has been awarded $24 million to advance translational research in South Carolina. The institute will partner with various institutions to develop bioinformatics tools, enhance clinical trial recruitment, and improve health outcomes.
Most clinical trial participants are not informed about the results of studies they participated in, despite wanting this information. Researchers want to share findings but lack effective communication skills to reach lay public. The study highlights the need for better training on communicating research results to study participants.
A prototype of a cloud-based informatics and resource-discovery tool will be built to help CTSA hubs measure their impact and compare efforts. The e-SPARC tool aims to provide a one-stop shop for investigators planning trials, while also supporting NCATS monitoring and improvements.
The European Society for Medical Oncology (ESMO) has announced the winners of its annual awards, recognizing Prof. Eric Van Cutsem's pioneering work in gastrointestinal oncology and Dr. Angelo Di Leo's lifetime achievements in cancer research and education. The ESMO Women for Oncology Award was also presented to Prof. Cristiana Sessa, ...
The University of Texas System, along with Rice University, is partnering to expand clinical and translational research in Texas, producing better health outcomes for those in Texas and across the nation. The expansion will focus on clinical studies designed to improve medical outcomes for underrepresented populations.
Researchers at MUSC discovered that silencing the gene Ccdc117 impedes rapid growth of precursor cells, leading to abnormal heart development. Exercise and improved nutrition may lessen the likelihood of heart malformations in fetuses.
The integrated Translational Health Research Institute of Virginia has been awarded a five-year grant to advance innovative ideas from discovery to implementation. The institute brings together partners with established strengths in biomedical research, data science, and clinical trials to transform translational research.
The National Foundation for Cancer Research (NFCR) has launched the Salisbury Award, a new program aimed at supporting translational cancer research. The award will provide funding and resources to researchers with early-stage projects deemed to have the best combination of novel and impactful technology.
A smaller portion of fish and chips has been developed by Newcastle University researchers, with the introduction of the Lite-BITE box. This smaller meal option, weighing around 600 calories, has been well-received by both customers and takeaway owners in the North of England and Scotland.
Researchers at Medical University of South Carolina identify insulin-like growth factor-binding protein 5 (IGFBP-5) as a potential therapeutic target for lung fibrosis. The protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors.
The University of Rochester has received a $8.39 million grant from the NIH to create a national center for child maltreatment studies. The TRANSFORM Center will focus on preventing child maltreatment and addressing its consequences through research, policy, and training initiatives.
The ESMO Award 2018 is bestowed on Jean-Charles Soria, a pioneer in developing anti-cancer drugs, while Tony Mok receives the ESMO Lifetime Achievement Award for his practice-changing contribution to lung cancer. Pasi Jänne and Margaret Foti also receive awards for their translational research and mentorship efforts, respectively.
The University of Oklahoma Health Sciences Center has renewed a $20 million federal grant to further research and patient care in Oklahoma. The program, Oklahoma Shared Clinical and Translational Resources, aims to improve health outcomes by conducting clinical and translational research with patients, particularly in rural areas.
Two MCG students, Saadia Hasan and Deeti Pithadia, have been selected to participate in the National Institutes of Health's Medical Research Scholars Program. The program allows them to conduct basic, clinical or translational research while pursuing their medical degrees.
A recent NIH-funded study found that applied science research produced a higher volume of translational research publications than basic science. The researchers analyzed 6,387 awards and determined that 7.4% of applied research publications were translational.
The National Institutes of Health has awarded Tufts Clinical and Translational Science Institute (CTSI) $56 million to support its local, regional, and national research initiatives. The funding will accelerate the translation of research into clinical use, medical practice, and impact on health.
The University of Minnesota's Clinical and Translational Science Institute has received $42.6 million in renewed NIH funding to accelerate discoveries that lead to treatments and cures for Minnesotans. The five-year award enables clinical and translational researchers across the UMN System and state to make important health discoveries.
Joseph Kaserman, MD, receives $225,000 award to study risk of liver disease in Alpha-1 carriers using induced pluripotent stem cells and CRISPR technology. The research aims to find new treatments for Alpha-1 related liver disease and address concerns of carrier individuals.
The Learning Health System Network (LHSNet) has outlined its approach to improving patient-centered clinical care through translational research. The network, involving nine health organizations and nearly 10 million patients, focuses on integrating stakeholders to inform research that aligns with patients' priorities.
The journal Drug Delivery and Translational Research published a special issue on ocular drug delivery, highlighting the need for sustainable release of therapeutics to target tissues in the posterior segment. The market opportunity is significant, with the global pharmaceutical market projected to grow to $23 billion by 2018.
A new cognitive behavioral therapy (CBT) resource has been developed to manage children's dental anxiety. The study found a significant reduction in dental anxiety and an increase in health-related quality of life among children who used the guided self-help CBT resource.
The NIH award will support initiatives such as engaging underrepresented persons in clinical trials and developing robust electronic platforms for data warehousing. This will enable the SC CTSI to advance cutting-edge research and scientific breakthroughs in patient and community health.
The IADR/AADR have released the first issue of JDR Clinical & Translational Research, a journal focusing on the translation of research into clinical practice. The inaugural issue covers various topics in applied oral health research, with an emphasis on rapid dissemination and application.
SAGE's new publication, JDR Clinical & Translational Research, expands on the success of Journal of Dental Research supplements. The journal accepts various study designs and methodologies, aiming to translate research findings into practical applications for oral health.
Rettsyndrome.org announces new Translational Research Awards to tackle nonsense mutations in MECP2 gene, aiming to develop treatments for Rett syndrome. The awards include the Read-Through Program and Neuro-Habilitation grants, furthering research towards new pharmacologic treatments and improved clinical practices.
A special issue of Biopreservation and Biobanking Journal explores China's biobanking strategy, highlighting its role in accelerating translational research. The articles discuss the country's biosample collection, analysis capabilities, and ethical management guidelines.
Vanderbilt University researchers found that chlorhexidine cloths did not reduce health care-associated infections in critically ill patients compared to non-antimicrobial cloths. The study analyzed data from over 9,300 ICU patients and showed no significant difference in infection rates between the two groups.
Columbia University has been awarded a $31 million NIH grant to create the Center for Excellence for Translational Research at Columbia's CII. The center will bring together researchers from diverse fields to develop insights into disease mechanisms and methods for detecting infectious agents.
The Block ICTR provides a comprehensive framework for translating biomedical discoveries into new treatments, with resources for community engagement, biostatistics, and clinical trials. Einstein and Montefiore will leverage their unique strengths to support innovative research programs across multiple disease areas.
The University of Utah Center for Clinical and Translational Science has received a $20.4 million grant from the NIH to advance translational research in medicine, particularly in rare conditions such as spinal muscular atrophy. The center will utilize this funding to support all aspects of translational research over the next five years.
The estate of Charles Meixner has donated $3 million to Autism Speaks, supporting translational postdoctoral fellowships and research into autism spectrum disorder. The gift will contribute to the development of new treatments and improve the lives of individuals and families affected by ASD.
A special issue of Translational Research highlights the progress and challenges of gene therapy research, focusing on clinically meaningful studies that combine patient observations with smart experiments. The approach of gene therapy may be applicable to all genetic disorders, offering a promising path for treatment and cure.
The ICTS will focus on translating genetic and genomic research into patient care, developing new therapeutics, and disseminating research findings. The grant supports Washington University's strengths in genetic and genomic research and its efforts to advance clinical and translational research.
The University of Missouri's Coulter Translational Partnership Program has awarded funding to five teams of physicians and engineers to improve healthcare. The program aims to turn laboratory discoveries into new products and services for patients, leveraging MU's substantial resources for biomedical innovation.
Researchers at the University of Utah will investigate the molecular causes of blood clots, which threaten millions of people worldwide. The center aims to apply basic science to find new diagnostic and therapeutic measures for thrombosis, making them available to patients rapidly.
The University of Michigan will use the funding to train researchers, provide tools and services, and involve more volunteers in their work. Over 11,000 people have already signed up for the registry.
Researchers found that small arteries showed signs of artery damage and reduced compliance after just six weeks on a high-fat diet, while large arteries remained unaffected. This early stage of damage may be the first step in developing high blood pressure.
The UNC Center for Diabetes Translation Research to Reduce Health Disparities aims to reduce diabetes-related disparities among poor and underserved populations. The center will leverage existing resources at NC TraCS Institute and partner with several universities and health departments to foster translational research.
The National Institutes of Health has awarded $200 million over five years to five health research centers to speed scientific discoveries into treatments for patients. The grants support the innovation and partnerships necessary to bridge basic research and medical practice.
The UK's NIHR Biomedical Research Centres have established a cutting-edge translational research infrastructure, driving progress in disease research and treatment. With strong focus on interdisciplinary working, public engagement, and industry partnerships, the centres aim to deliver rapid benefits for patients.
Dr. Thomas J. Walsh, Director of the Transplantation-Oncology Infectious Diseases Program at Weill Cornell Medical College, has been selected as the 2010 laureate of the sanofi-aventis ICAAC Award for his groundbreaking work on antifungal pharmacology and therapeutics.
The Prostate Cancer Translational Research in Europe meeting showcased ongoing research efforts to identify biomarkers, genetic variants and new therapeutic options. Researchers discussed the importance of collaboration between clinicians and scientists to streamline current efforts and avoid duplication.
The University of Cincinnati has been awarded nearly $23 million by the National Institutes of Health to support clinical and translational science research. The funding will be used to enhance research capabilities, increase community engagement, and facilitate interdisciplinary collaboration.
A new set of tools, 'Pathways to Clinical Goals,' aims to improve the translational research process, accelerating cancer therapy approval. The six pathways address various categories, including anti-cancer agents and lifestyle alterations, to clarify and streamline the research process.
The National Institutes of Health has awarded a $25 million Clinical and Translational Science Award to Indiana University School of Medicine. The grant will fund translational research activities at IU and Purdue universities, combining strengths in medicine, business, and government.
The International Diabetes Federation has supported a diabetes awareness and prevention project in Jordan, aiming to reverse the growing epidemic. The project aims to provide health education opportunities and practical experience through workshops and social support groups.
The Boston University Clinical and Translational Science Institute will integrate research across departments and schools, facilitating interactions and incorporating community-based needs. The award aims to improve treatment efficiency and access to patient care.