Articles tagged with Translational Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The European Society for Medical Oncology (ESMO) has announced the winners of its annual awards, recognizing Prof. Eric Van Cutsem's pioneering work in gastrointestinal oncology and Dr. Angelo Di Leo's lifetime achievements in cancer research and education. The ESMO Women for Oncology Award was also presented to Prof. Cristiana Sessa, ...
The University of Texas System, along with Rice University, is partnering to expand clinical and translational research in Texas, producing better health outcomes for those in Texas and across the nation. The expansion will focus on clinical studies designed to improve medical outcomes for underrepresented populations.
Researchers at MUSC discovered that silencing the gene Ccdc117 impedes rapid growth of precursor cells, leading to abnormal heart development. Exercise and improved nutrition may lessen the likelihood of heart malformations in fetuses.
The integrated Translational Health Research Institute of Virginia has been awarded a five-year grant to advance innovative ideas from discovery to implementation. The institute brings together partners with established strengths in biomedical research, data science, and clinical trials to transform translational research.
The National Foundation for Cancer Research (NFCR) has launched the Salisbury Award, a new program aimed at supporting translational cancer research. The award will provide funding and resources to researchers with early-stage projects deemed to have the best combination of novel and impactful technology.
A smaller portion of fish and chips has been developed by Newcastle University researchers, with the introduction of the Lite-BITE box. This smaller meal option, weighing around 600 calories, has been well-received by both customers and takeaway owners in the North of England and Scotland.
Researchers at Medical University of South Carolina identify insulin-like growth factor-binding protein 5 (IGFBP-5) as a potential therapeutic target for lung fibrosis. The protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors.
The University of Rochester has received a $8.39 million grant from the NIH to create a national center for child maltreatment studies. The TRANSFORM Center will focus on preventing child maltreatment and addressing its consequences through research, policy, and training initiatives.
The ESMO Award 2018 is bestowed on Jean-Charles Soria, a pioneer in developing anti-cancer drugs, while Tony Mok receives the ESMO Lifetime Achievement Award for his practice-changing contribution to lung cancer. Pasi Jänne and Margaret Foti also receive awards for their translational research and mentorship efforts, respectively.
The University of Oklahoma Health Sciences Center has renewed a $20 million federal grant to further research and patient care in Oklahoma. The program, Oklahoma Shared Clinical and Translational Resources, aims to improve health outcomes by conducting clinical and translational research with patients, particularly in rural areas.
Two MCG students, Saadia Hasan and Deeti Pithadia, have been selected to participate in the National Institutes of Health's Medical Research Scholars Program. The program allows them to conduct basic, clinical or translational research while pursuing their medical degrees.
A recent NIH-funded study found that applied science research produced a higher volume of translational research publications than basic science. The researchers analyzed 6,387 awards and determined that 7.4% of applied research publications were translational.
The National Institutes of Health has awarded Tufts Clinical and Translational Science Institute (CTSI) $56 million to support its local, regional, and national research initiatives. The funding will accelerate the translation of research into clinical use, medical practice, and impact on health.
The University of Minnesota's Clinical and Translational Science Institute has received $42.6 million in renewed NIH funding to accelerate discoveries that lead to treatments and cures for Minnesotans. The five-year award enables clinical and translational researchers across the UMN System and state to make important health discoveries.
Joseph Kaserman, MD, receives $225,000 award to study risk of liver disease in Alpha-1 carriers using induced pluripotent stem cells and CRISPR technology. The research aims to find new treatments for Alpha-1 related liver disease and address concerns of carrier individuals.
The Learning Health System Network (LHSNet) has outlined its approach to improving patient-centered clinical care through translational research. The network, involving nine health organizations and nearly 10 million patients, focuses on integrating stakeholders to inform research that aligns with patients' priorities.
The journal Drug Delivery and Translational Research published a special issue on ocular drug delivery, highlighting the need for sustainable release of therapeutics to target tissues in the posterior segment. The market opportunity is significant, with the global pharmaceutical market projected to grow to $23 billion by 2018.
A new cognitive behavioral therapy (CBT) resource has been developed to manage children's dental anxiety. The study found a significant reduction in dental anxiety and an increase in health-related quality of life among children who used the guided self-help CBT resource.
The NIH award will support initiatives such as engaging underrepresented persons in clinical trials and developing robust electronic platforms for data warehousing. This will enable the SC CTSI to advance cutting-edge research and scientific breakthroughs in patient and community health.
The IADR/AADR have released the first issue of JDR Clinical & Translational Research, a journal focusing on the translation of research into clinical practice. The inaugural issue covers various topics in applied oral health research, with an emphasis on rapid dissemination and application.
SAGE's new publication, JDR Clinical & Translational Research, expands on the success of Journal of Dental Research supplements. The journal accepts various study designs and methodologies, aiming to translate research findings into practical applications for oral health.
Rettsyndrome.org announces new Translational Research Awards to tackle nonsense mutations in MECP2 gene, aiming to develop treatments for Rett syndrome. The awards include the Read-Through Program and Neuro-Habilitation grants, furthering research towards new pharmacologic treatments and improved clinical practices.
A special issue of Biopreservation and Biobanking Journal explores China's biobanking strategy, highlighting its role in accelerating translational research. The articles discuss the country's biosample collection, analysis capabilities, and ethical management guidelines.
Vanderbilt University researchers found that chlorhexidine cloths did not reduce health care-associated infections in critically ill patients compared to non-antimicrobial cloths. The study analyzed data from over 9,300 ICU patients and showed no significant difference in infection rates between the two groups.
Columbia University has been awarded a $31 million NIH grant to create the Center for Excellence for Translational Research at Columbia's CII. The center will bring together researchers from diverse fields to develop insights into disease mechanisms and methods for detecting infectious agents.
The Block ICTR provides a comprehensive framework for translating biomedical discoveries into new treatments, with resources for community engagement, biostatistics, and clinical trials. Einstein and Montefiore will leverage their unique strengths to support innovative research programs across multiple disease areas.
The University of Utah Center for Clinical and Translational Science has received a $20.4 million grant from the NIH to advance translational research in medicine, particularly in rare conditions such as spinal muscular atrophy. The center will utilize this funding to support all aspects of translational research over the next five years.
The estate of Charles Meixner has donated $3 million to Autism Speaks, supporting translational postdoctoral fellowships and research into autism spectrum disorder. The gift will contribute to the development of new treatments and improve the lives of individuals and families affected by ASD.
A special issue of Translational Research highlights the progress and challenges of gene therapy research, focusing on clinically meaningful studies that combine patient observations with smart experiments. The approach of gene therapy may be applicable to all genetic disorders, offering a promising path for treatment and cure.
The ICTS will focus on translating genetic and genomic research into patient care, developing new therapeutics, and disseminating research findings. The grant supports Washington University's strengths in genetic and genomic research and its efforts to advance clinical and translational research.
The University of Missouri's Coulter Translational Partnership Program has awarded funding to five teams of physicians and engineers to improve healthcare. The program aims to turn laboratory discoveries into new products and services for patients, leveraging MU's substantial resources for biomedical innovation.
Researchers at the University of Utah will investigate the molecular causes of blood clots, which threaten millions of people worldwide. The center aims to apply basic science to find new diagnostic and therapeutic measures for thrombosis, making them available to patients rapidly.
The University of Michigan will use the funding to train researchers, provide tools and services, and involve more volunteers in their work. Over 11,000 people have already signed up for the registry.
Researchers found that small arteries showed signs of artery damage and reduced compliance after just six weeks on a high-fat diet, while large arteries remained unaffected. This early stage of damage may be the first step in developing high blood pressure.
The UNC Center for Diabetes Translation Research to Reduce Health Disparities aims to reduce diabetes-related disparities among poor and underserved populations. The center will leverage existing resources at NC TraCS Institute and partner with several universities and health departments to foster translational research.
The National Institutes of Health has awarded $200 million over five years to five health research centers to speed scientific discoveries into treatments for patients. The grants support the innovation and partnerships necessary to bridge basic research and medical practice.
The UK's NIHR Biomedical Research Centres have established a cutting-edge translational research infrastructure, driving progress in disease research and treatment. With strong focus on interdisciplinary working, public engagement, and industry partnerships, the centres aim to deliver rapid benefits for patients.
Dr. Thomas J. Walsh, Director of the Transplantation-Oncology Infectious Diseases Program at Weill Cornell Medical College, has been selected as the 2010 laureate of the sanofi-aventis ICAAC Award for his groundbreaking work on antifungal pharmacology and therapeutics.
The Prostate Cancer Translational Research in Europe meeting showcased ongoing research efforts to identify biomarkers, genetic variants and new therapeutic options. Researchers discussed the importance of collaboration between clinicians and scientists to streamline current efforts and avoid duplication.
The University of Cincinnati has been awarded nearly $23 million by the National Institutes of Health to support clinical and translational science research. The funding will be used to enhance research capabilities, increase community engagement, and facilitate interdisciplinary collaboration.
A new set of tools, 'Pathways to Clinical Goals,' aims to improve the translational research process, accelerating cancer therapy approval. The six pathways address various categories, including anti-cancer agents and lifestyle alterations, to clarify and streamline the research process.
The International Diabetes Federation has supported a diabetes awareness and prevention project in Jordan, aiming to reverse the growing epidemic. The project aims to provide health education opportunities and practical experience through workshops and social support groups.
The Boston University Clinical and Translational Science Institute will integrate research across departments and schools, facilitating interactions and incorporating community-based needs. The award aims to improve treatment efficiency and access to patient care.
The National Institutes of Health has awarded a $25 million Clinical and Translational Science Award to Indiana University School of Medicine. The grant will fund translational research activities at IU and Purdue universities, combining strengths in medicine, business, and government.
The IDF BRIDGES translational research grant program will fund a pilot study in the Philippines that aims to improve diabetes care in rural communities using local health workers. The program, called Diabetes Self-Management Program (DSME), will provide culturally-appropriate education and self-care practices for Filipinos with diabetes.
Jeffrey A. Toretsky, a pediatric oncology physician and researcher at Georgetown University's Lombardi Comprehensive Cancer Center, has received a prestigious Clinical Scientist Award in Translational Research from the Burroughs Wellcome Fund. The award will support his research to identify molecular mechanisms of EWS-FLI1 and develop ...
The Burroughs Wellcome Fund has awarded $9.75 million to 13 translational researchers through its Clinical Scientist Awards in Translational Research. These awards support established physician-scientists exploring scientific questions, applying knowledge at the bedside, and bringing insights back to the laboratory.
The Johns Hopkins Institute for Clinical and Translational Research (ICTR) aims to speed up the translation of promising research from labs to clinics and eventually to communities. The ICTR will support over 100 faculty members across various schools, enabling them to form relationships with outside organizations and partner with heal...
The University of Wisconsin-Madison's Institute for Clinical and Translational Research (ICTR) has received a $41 million NIH grant to build a network of partners across campus and around the state. This initiative aims to accelerate biomedical discoveries into practical healthcare applications, with a focus on community-based research...
The National Institutes of Health has awarded the University of Chicago Medical Center nearly $23 million to conduct translational research. This project aims to develop personalized therapies and improve access to medical care for the diverse population of the South Side of Chicago, where health disparities are prevalent.
The NCRR has launched a Translational Research Network to facilitate multi-site clinical and translational research among minority institutions. The network will enable researchers to pool resources and expertise, increasing the productivity and impact of individual centers.
The Burroughs Wellcome Fund has awarded a total of $8.25 million to support established physician-scientists conducting translational research. This funding will enable these researchers to explore scientific questions, apply their knowledge at the bedside, and bring insights back to the laboratory.
A new NIH-funded program co-directed by the Mailman School faculty will expedite clinical research, transforming how medical discovery is made. The center will centralize core resources for clinical researchers and enhance collaboration among scientific communities.
The NIH will provide $54 million over five years to Columbia University Medical Center to establish an Irving Institute for Clinical and Translational Research. This investment will enable the expansion of core resources available to clinical researchers, including biomedical informatics support and biostatistical analysis.
Rockefeller University has been awarded a Clinical and Translational Science Award (CTSA) of over $45 million to enhance its infrastructure for translating scientific discoveries into improved health. The award will support translational researchers and train physician-scientists in clinical research.
The University of Pittsburgh is awarded a $83.5 million NIH grant to establish the Clinical and Translational Science Institute (CTSI), aiming to transform clinical research and improve patient care. The CTSI will foster clinical and translational research, promote access to clinical trials, and develop novel methodologies.
The UCSF Institute will support innovative approaches in translational and clinical science across four schools, with a focus on accelerating the pace of scientific discovery into patient care. The institute's goal is to find more efficient ways to move basic research findings into the clinic.
Dr. Kodadek's research aims to develop substances that can diagnose and block specific immune responses without suppressing the entire immune system, potentially treating autoimmune diseases and cancer. He will receive $500,000 per year for five years to pursue this innovative approach.
Advances in biology are hindered by obstacles such as dwindling National Institutes of Health budgets and overly burdensome regulatory requirements. The Association of American Medical Colleges has outlined key recommendations to promote translational research, including increased investment in medical schools and teaching hospitals.
Two Yale Biomedical Engineers, Erin Lavik and Tarek Fahmy, have received Early Career Translational Research Awards for their innovative projects on glaucoma treatment and autoimmune disease diagnosis. The awards support their research collaborations with clinical investigators and provide two years of funding.