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'Gene Therapy for Human Disease: Clinical Advances and Challenges'

A special issue of Translational Research highlights the progress and challenges of gene therapy research, focusing on clinically meaningful studies that combine patient observations with smart experiments. The approach of gene therapy may be applicable to all genetic disorders, offering a promising path for treatment and cure.

SourceElsevier·JournalTranslational Research·DateMar 21, 2013

$50 million to speed discoveries for patients

The ICTS will focus on translating genetic and genomic research into patient care, developing new therapeutics, and disseminating research findings. The grant supports Washington University's strengths in genetic and genomic research and its efforts to advance clinical and translational research.

Arteries under pressure early on

Researchers found that small arteries showed signs of artery damage and reduced compliance after just six weeks on a high-fat diet, while large arteries remained unaffected. This early stage of damage may be the first step in developing high blood pressure.

SourceSpringer·JournalJournal of Cardiovascular Translational Research·DateApr 3, 2012

Strategies for translational research in the UK

The UK's NIHR Biomedical Research Centres have established a cutting-edge translational research infrastructure, driving progress in disease research and treatment. With strong focus on interdisciplinary working, public engagement, and industry partnerships, the centres aim to deliver rapid benefits for patients.

SourceKing's College London·JournalScience Translational Medicine·DateOct 21, 2010

How can advances in biology be translated into better health?

Advances in biology are hindered by obstacles such as dwindling National Institutes of Health budgets and overly burdensome regulatory requirements. The Association of American Medical Colleges has outlined key recommendations to promote translational research, including increased investment in medical schools and teaching hospitals.

SourcePLOS·JournalPLOS Medicine·DateSep 4, 2006

NIH launches major program to transform clinical and translational science

The NIH Clinical and Translational Science Awards (CTSAs) program aims to energize clinical and translational science at academic health centers nationwide. The program will foster collaborative approaches, encourage creative research methods, and lead to better patient outcomes through new prevention strategies and treatments.

SourceNIH/National Center for Advancing Translational Sciences (NCATS)·JournalNew England Journal of Medicine·DateOct 12, 2005