Researchers at the University of Missouri School of Medicine have discovered a potential cure for Type 1 diabetes by combining adult stem cells with a new drug. The discovery reveals that blood vessels are essential for insulin production and repairing them can help restore insulin-making cells.
Researchers redefined a key regulatory process in the defective protein responsible for cystic fibrosis, providing a theory on how Vx-770 works. The study identified a novel strategy to complement and enhance the performance of existing drugs, opening up therapeutic possibilities for other diseases.
Researchers identified significant sections of the dystrophin gene that could provide hope to young patients and families with Duchenne muscular dystrophy. The discovery found a 'claw' in the gene that brings nNOS to the muscle cell membrane, preventing damage and potentially leading to treatments.
Scientists at the University of Missouri are working on a $3.4 million NIH project to create next-generation antiviral therapies by targeting the elusive HIV enzyme RNase H. The goal is to be ready for evolving resistant strains before they emerge, offering new treatment options.
Elizabeth Garrett, MD, receives American Academy of Family Physicians' highest honor in education for her career contributions to family medicine education. She has improved training in family medicine across the country for nearly three decades through curriculum development and teacher development programs.
Dr. James Sowers, a renowned endocrinologist, has received the American Heart Association's Lifetime Achievement Award for his pioneering work on the deadly link between cardiovascular disease and diabetes. His research has significantly advanced our understanding of insulin action, vascular biology, and metabolic disorders.
The University of Missouri's Coulter Translational Partnership Program has awarded funding to five teams of physicians and engineers to improve healthcare. The program aims to turn laboratory discoveries into new products and services for patients, leveraging MU's substantial resources for biomedical innovation.
The University of Missouri will use the grant to create a program called LIGHT2, which combines advanced technology with education for patients and providers. The high-tech component leverages MU's partnership with Cerner Corporation to improve health outcomes and reduce costs.
Researchers have developed a new therapy that targets a specific enzyme to stop the spread of brain bleeds and protect brain cells from further damage after a stroke. The compound has potential for use in both ischemic and hemorrhagic strokes, offering a longer window of treatment for patients.
A new NIH grant will help Missouri University School of Medicine students learn how to address public health issues, become lifelong learners, and deliver effective patient-centered care. The program will also enhance training in behavioral and social sciences with a focus on cultural competency and narrative-based learning.
Researchers discovered a promising alternative to common antibiotics for treating group A Streptococcus (GAS) bacteria infections. The new compounds significantly reduce the severity of GAS infections in mice, offering a potential therapeutic solution with reduced risk of antibiotic resistance.
Researchers are studying two enzymes to combat the flu virus, which causes 36,000 US deaths and 200,000 hospitalizations annually. The goal is to identify targets for drug therapies that can block the spread of the influenza virus.
Researchers found that partying, drinking, and work trigger smoking recall among college students, who tend to start smoking at the beginning of the semester and on weekends. The study suggests targeting interventions during these periods for maximum impact.
Michael LeFevre, a renowned family medicine leader, has been elected to the Institute of Medicine. As a distinguished expert in prevention, detection, and treatment of high blood pressure, he will contribute to evidence-based medicine and improve health care outcomes.
The University of Missouri's Rural Track Pipeline Program has produced nearly 65% of its graduates staying in Missouri, with over 57% practicing in rural areas. The program offers multiple opportunities for medical students to train and live in rural communities, addressing the national physician shortage in rural areas.
Researchers at the University of Missouri have developed a nanotechnology sensor that can detect lung cancer in blood plasma with high sensitivity and selectivity. This technology could provide an earlier warning signal, potentially saving lives. The sensor detects changes in a specific microRNA molecule associated with lung cancer.
Researchers discovered a molecular link between pesticides and Parkinson's disease, shedding light on the oxidative stress that contributes to the neurodegenerative disorder. The study provides evidence that exposure to environmental toxins may be a primary cause of Parkinson's, with potential implications for prevention and treatment.
A $3.25 million federal grant will enhance services for over 1,200 children and families in Missouri, focusing on physical, emotional, social, cognitive, and behavioral development. The LAUNCH project aims to create a coordinated support system to help children thrive in safe environments.
Researchers have made significant breakthroughs in understanding how HIV mutates and evades treatment, providing new insights into developing better tests and treatments for patients. The study found that a specific mutation allows the virus to resist two main families of drugs, highlighting the need for tailored therapies.
A new $2.1 million NIH grant will help MU scientist Dongsheng Duan develop a treatment that prevents heart muscles from weakening due to Duchenne muscular dystrophy. Tests have shown that treating skeletal muscle alone can lead to complications, highlighting the need for comprehensive treatment targeting both skeletal and cardiac muscle.