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Science News for July 24, 2007


Enzyme discovery sheds light on vitamin D

Researchers at Queen's University have made a groundbreaking discovery about the breakdown of vitamin D, revealing that changing a single amino acid in the hydroxylase enzyme can alter its pathway. This finding has significant implications for the treatment of cancer and other diseases associated with vitamin D deficiency.

SourceQueen's University·JournalProceedings of the National Academy of Sciences·DateJul 24, 2007

Switchable adhesive

Scientists create a surface pair that sticks together in response to an environmental stimulus, allowing for reversible detachment. This discovery could lead to innovative applications in microfluidic systems, actuators, and pharmacological agents.

SourceWiley·DateJul 24, 2007

New model for autism suggests women carry the disorder and explains age as a risk factor

Researchers at Cold Spring Harbor Laboratory propose a new model for understanding how autism is acquired, suggesting that spontaneous germ-line mutation is a significant cause. This mutation can be carried by women without severe symptoms and passed on to their children, increasing the risk of sons developing autism.

SourceCold Spring Harbor Laboratory·JournalProceedings of the National Academy of Sciences·DateJul 24, 2007

Older is better -- Top-10 comparison of diabetes drugs give metformin top grade

A study by Johns Hopkins Medicine found that metformin, a widely used diabetes medication, offers distinct advantages over nine other medications in controlling blood sugar levels, weight gain, and bad cholesterol levels. The medication was also found to be less expensive than newer options, with annual treatment costs averaging $100.

SourceJohns Hopkins Medicine·JournalAnnals of Internal Medicine·DateJul 24, 2007

Success rates for prostate cancer depend on experience of surgeon

A study published in the Journal of the National Cancer Institute found that experienced surgeons perform more successful prostate cancer surgeries, with a steeper learning curve. As surgeons gain experience, patient outcomes improve, but beyond 250 operations, additional experience has little influence on cancer recurrence rates.

SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJul 24, 2007

How to structure a complex body plan

Researchers found that plastic morphometric characters are associated with branch level and fixed traits with colony level in Stylophora pistillata corals. This adaptive plasticity allows the formation of species-specific architecture through variable developmental routes.

SourcePLOS·JournalPLOS ONE·DateJul 24, 2007

Chandra catches 'piranha' black holes

A new study using Chandra finds that younger, more distant galaxy clusters contain far more actively growing supermassive black holes than older, nearby ones. This rapid growth allows these black holes to thrive and influence their host galaxies.

SourceChandra X-ray Center·JournalThe Astrophysical Journal Letters·DateJul 24, 2007

Outcome of prostate cancer surgery depends on the experience of the surgeon

A new study published in the Journal of the National Cancer Institute found that prostate cancer patients treated by experienced surgeons have a lower risk of recurrence five years after surgery. The study analyzed data from over 7,700 patients and found that surgeons with more experience had better outcomes, with nearly 70% fewer recu...

SourceMemorial Sloan Kettering Cancer Center·JournalJNCI Journal of the National Cancer Institute·DateJul 24, 2007

Breast cancer and hormone therapy -- A looking-glass mirror?

A new Kaiser Permanente study suggests a possible link between breast cancer incidence and postmenopausal hormone therapy (HT) use, but concludes that the association is complex and influenced by various factors, including mammography screening rates. Long-term HT may slightly increase breast cancer risk, particularly in younger women.

SourceInternational Menopause Society·JournalJNCI Journal of the National Cancer Institute·DateJul 24, 2007