Articles tagged with Alcoholism
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A study found that prenatal alcohol exposure changed aspects of the dopamine system in rhesus monkeys, influencing how quickly they drank alcohol in adulthood. The researchers also discovered individualized neuroadaptive responses to drinking, which may promote the transition to alcohol use disorder.
A cohort study of 47,000 adults found that males had a 63% greater risk of all-cause mortality compared to females after adjusting for demographic and behavioral factors. The study suggests intrinsic biological factors, such as sex hormones or immune response, may contribute to these sex differences in mortality.
A UH psychologist's study finds that anxiety sensitivity and pain-related anxiety are linked to mental health problems and clinically significant alcohol use among survivors of traumatic sexual assault. The investigation highlights the importance of addressing both types of anxiety in reducing the risk of lifelong challenges.
Research reveals that higher lifetime alcohol consumption is associated with a higher risk of colorectal cancer, especially for rectal cancer. Quitting drinking can lower a person’s risk, according to the findings published in CANCER, a peer-reviewed journal.
A new study in NC found that many residential substance-use service providers require patients to engage in unpaid labor, restricting access to evidence-based treatment. Providers with labor requirements are less likely to offer recommended treatment and more likely to operate without a state license.
A preclinical study shows that cannabidiol restores emotional behavior, reduces alcohol-related vulnerability, and reverses gut microbiota alterations caused by prenatal alcohol exposure. Female mice particularly benefited from CBD treatment, which normalized their emotional alterations and eliminated vulnerability to alcohol addiction.
Research found that prolonged heavy drinking induces neuroinflammation, promoting negative emotional states lasting for weeks into abstinence. Inhibiting proinflammatory microglia activation during alcohol exposure blocks the development of anxiety and fear memory.
A study published in Drug and Alcohol Review journal reveals that workplace factors like long hours, work-related stress, and shift work do not solely drive high-risk drinking. Personal and social factors have an even greater impact on alcohol consumption among workers. The research analyzed over two decades of data from the Household ...
New research suggests that mobile health interventions tailored to individual needs can reduce harms associated with heavy drinking and cannabis use. Studies demonstrate the effectiveness of personalized feedback and protective behavioral strategies in reducing substance use risks, paving the way for innovative digital interventions.
A new protocol models alcoholism in mice and shows that stimulating the FGF21-oxytocin-dopamine system with rare sugars can reduce alcohol consumption. The researchers believe that this system may play a role in regulating subconscious information processing, leading to effective dietary therapy for reducing over-drinking.
The study found a significant increase in alcohol-related hospitalizations between 2016 and 2022, with rising mortality rates and extended lengths of stay. Preventive efforts are needed to reduce population-level alcohol consumption and improve treatment outcomes for individuals with alcohol use disorder.
Researchers found altered gene expression in the brain's stress-processing hub, and inhibiting signaling pathways reduced relapse-like behavior. However, blocking both signals simultaneously cancelled this effect, highlighting potential risks of combining treatments.
A new study finds that raising the minimum legal drinking age from 16 to 18 years significantly improves academic performance and mental health among European teenagers. The research, conducted by Carmen Villa, shows a decrease in binge drinking and intoxication, leading to better PISA exam scores and reduced anxiety medication use.
A study published by Michigan Medicine suggests that AI can help increase the chance of people with risky drinking patterns or signs of alcohol use disorder getting outreach and help. The NLP tool analyzed full text of health records and identified over 47,500 patients with some sign of risky drinking.
A new review of 'Dry January' found that even a short break from alcohol can lead to meaningful physical and psychological improvements. Participants reported improved sleep, better mood, weight loss, and healthier liver function.
A new study found that nearly half of patients discharged with take-home methadone successfully connected to treatment within 72 hours. The likelihood of successful follow-up increased if patients were already enrolled in an OTP or received higher methadone doses.
A new study from Weill Cornell Medicine reveals distinct patterns of brain activity between boys and girls with a family history of substance use disorder, suggesting separate predispositions for addiction. Girls with a family history displayed higher transition energy in the default-mode network, indicating greater difficulty disengag...
A new study found that smoking marijuana can temporarily cut down how much people drink, with participants reducing their alcohol intake by 19-27% when using cannabis. However, the researchers caution that more study is needed to determine long-term effects and potential risks of cannabis use.
A new compound MCH11, a monoacylglycerol lipase inhibitor, shows promising effects in reducing alcohol consumption and motivation to drink in mice. The molecule exhibits anxiolytic and antidepressant properties with sex-dependent efficacy, correcting genetic alterations associated with alcohol use disorder.
Researchers discovered psilocin's mechanism to reduce alcohol use in female mice by dampening activity of neurons in the central amygdala, leading to decreased drinking. This finding provides mechanistic insight into psychedelic treatment for psychiatric disorders like depression and anxiety.
Researchers found that heavy drinkers experienced strokes a decade earlier and with greater severity than non-heavy drinkers. Heavy drinking was also linked to signs of cerebral small vessel disease, which causes long-term brain damage.
A study published in the Journal of Neuroscience found that mutations in the CHRNA3 gene are associated with lowered sensitivity to alcohol and delayed avoidance behavior. This suggests that normal function of the chrna3 gene helps control alcohol exposure, leading to individual differences in alcohol sensitivity.
A culturally adapted behavioral intervention delivered in Spanish by community health workers significantly reduced unhealthy alcohol use among Latinx adults. Participants showed nearly twice the reduction in heavy drinking days compared to those who received an educational booklet.
A new study by Flinders University found that abstention from alcohol is on the rise, particularly among younger cohorts, with Generation Z nearly 20 times more likely to choose not to drink compared to Baby Boomers. The study suggests a clear generational shift, with declining weekly alcohol consumption and changing social norms drivi...
Researchers at Washington State University have discovered that altering brain function in the cerebellum region can ease physical and emotional symptoms of alcohol withdrawal. The study used genetic tools and a synthetic compound to achieve this, offering a promising new approach to treating alcohol use disorder.
The SHC-SHG program leads to a 16% reduction in LRDs among self-employed individuals, while unemployed individuals show significant behavioral changes but not health improvements. The increase in municipal funds is found to be cost-effective, with overall medical expenses reduced by nine times the increase.
A systematic review and meta-analysis found a strong association between alcohol consumption per capita and an increase in suicide mortality rates. The study suggests that targeting alcohol consumption may be a useful strategy for comprehensive national suicide prevention efforts.
Researchers at UC Berkeley find that chimpanzees consume about 14 grams of pure ethanol per day, equivalent to one standard American drink. This chronic exposure suggests a dietary heritage of alcohol from our common ancestor with chimpanzees.
A new study by Scripps Research scientists reveals that a small midline brain region plays a key role in how animals learn to continue drinking to avoid withdrawal symptoms. This brain pathway is responsible for driving strong relapse behavior, making it a crucial target for developing new treatments for substance use disorders.
A UIC researcher team led by Dr. Subhash C. Pandey will investigate how long-term alcohol use affects the structure and function of brain cells, aiming to improve targeted treatments for alcohol use disorder. The grant renewal aims to fuel cutting-edge research into cellular interaction in areas key to alcohol addiction.
A new study finds that college students who are exposed to a drinker's poor behavior experience lower grades, mental distress, and suicidal thoughts. The researchers surveyed 1,822 students and found that being harassed or physically harmed was associated with poor academic performance and worse mental health.
A comprehensive study published in the Journal of Hepatology shows that healthy eating and increased physical activity significantly lower the risk of liver-related death, even among heavy and binge drinkers. The research analyzed data from over 60,000 US adults and found that adherence to high levels of physical activity and/or diet q...
Researchers at University of California San Diego School of Medicine found that chronic alcohol use impairs gut bacterial regulation. This allows bacteria to migrate to the liver, worsening ALD. Targeting this mechanism with existing drugs may provide a new approach to minimizing liver damage from alcohol use.
A study investigated approach/avoidance tendencies in male AUD patients through a gait initiation task, using posturography. The findings suggest that analyzing micromovements and reaction times may help predict if individuals will relapse following treatment.
Researchers at Emory University developed two affordable programs to prevent youth substance misuse: Connect Kits for Family Action and Connect Brief Intervention. A randomized trial found that these programs reduced alcohol and other substance use among high school students in rural Oklahoma.
A study from University of Louisville researchers found that perfluorooctane sulfonate (PFOS) can worsen liver damage when combined with alcohol consumption. The study showed that PFOS exposure can increase fat accumulation and markers of liver damage, disrupt the liver's ability to manage fats, and activate pathways that promote liver...
A nationwide study found that alcohol withdrawal syndrome significantly increases risks of complications and longer hospital stays after major surgery. Proactive screening and multidisciplinary care can help prevent such complications.
Researchers used machine learning to predict patient outcomes in hospitalized cirrhosis patients, outperforming traditional methods. The study found that AI can help hospital teams triage and prioritize patients more effectively.
The Be Well Texas initiative, led by the University of Texas Health Science Center at San Antonio, will expand access to opioid use disorder treatment services and recovery support across rural and urban communities. This major statewide expansion aims to reduce overdose deaths and build a lasting recovery infrastructure.
A clinical trial found that women experience stronger subjective effects of acute alcohol intake, such as drunkenness and sedation, compared to men. The study adjusted doses to achieve identical blood alcohol concentrations for both sexes, revealing that women's effects were more intense.
This cross-sectional study reveals a substantial rise in alcohol-associated liver disease mortality, particularly among women and younger adults. The findings highlight the importance of targeted public health initiatives to address this growing health concern.
Researchers have identified a specific group of neurons in the brain responsible for suppressing binge drinking behavior. The discovery may lead to new therapeutic targets for treating alcohol dependency and related health challenges.
A study by Scripps Research found that female rats are more sensitive to alcohol's effects on brain chemistry, even before dependence sets in. The research suggests that certain medications targeting specific receptors could help reduce alcohol consumption in females.
Researchers found that ibudilast works better for women who have lower levels of depression and inflammation. The study, which recruited 102 adults with moderate or severe alcohol use disorder, showed that ibudilast did not reduce drinking in most participants, but had a positive effect on female participants.
A WVU microbiology student has discovered a new species of fungus, Periglandula clandestina, that produces effects similar to the semisynthetic drug LSD. The fungus is highly efficient at making ergot alkaloids, which can be used therapeutically to treat conditions like depression and addiction.
A study found that fewer than half of U.S. adults are aware of the link between alcohol and cancer, highlighting a need for increased awareness and action. The findings emphasize the importance of reducing the alcohol-related cancer burden in the US.
A new study found that collegiate recovery programs with multiple funding sources served twice as many students, providing dedicated space and relapse management support. These programs offer inclusive All Recovery meetings, which provide a welcoming space for students on different recovery journeys to connect and heal.
A new study published in the Journal of Child Psychology and Psychiatry reveals that childhood trauma significantly increases the likelihood of engaging in risky behaviors, including harmful alcohol consumption, smoking, and illicit drug use. The research also found an unexpected connection between trauma and cardiovascular health, wit...
Apremilast reduces both drinking and pain sensitivity in preclinical models of alcohol use disorder, with significant effects observed across biological sexes and strains. The study suggests apremilast could be repurposed as a dual-acting therapy for AUD, particularly in individuals with pain during and after alcohol use.
A study found that hazardous drinking and daily alcohol consumption were associated with increased odds of abusive and neglectful behaviors among family caregivers of patients with dementia. The findings suggest the importance of addressing caregiving complexities and alcohol use patterns through personalized interventions.
A new study found that both oral and injectable forms of naltrexone are effective in reducing heavy drinking among hospitalized patients. The medication was administered before discharge, resulting in a significant decrease in heavy drinking within the last 30 days of the three-month follow-up period.
Recent study analysis found that young adult females in the US experience higher rates of past-month binge drinking compared to males. In contrast, older male groups continue to exhibit higher binge drinking rates.
A new study found that death rates from alcohol in England increased by a fifth in 2020, rising further between 2020 and 2022. The largest increases were among men, people from deprived areas, and those aged 50-69, mainly due to liver damage caused by alcohol.
Researchers from Yale University found that participation in faith-based or community-based extracurricular activities can increase U.S. adolescents' awareness of the dangers of binge drinking. The study suggests that these types of activities could play a crucial role in preventing excessive alcohol consumption among young people.
Rats exposed to high amounts of alcohol demonstrated poor decision-making during a complex task even after a monthslong withdrawal period. The team linked the behavioral difficulties to dramatic functional transformations in the dorsomedial striatum, a part of the brain critical for decision-making.
Researchers found females with a history of binge eating start drinking alcohol quicker than males. Increased levels of phosphodiesterase 4B (PDE4B) prevent cooccurrence of binging in both sexes of mice.
Brandi Fink's Personal Alcohol Management System (PALMS) uses iPad-based assessments to identify patients with an alcohol use disorder and provide personalized feedback. The system has shown promise in improving patient-provider discussions and reducing drinking levels, with plans for integration into electronic health records.
Researchers are testing a brain pacemaker to treat severe alcohol and opioid addiction, aiming to develop effective treatments and understand the brain mechanisms driving addiction disorders. The trial, known as Brain-PACER, uses deep brain stimulation to modulate brain activity and cravings.
A new study found that sports gambling frequency is associated with the trajectory of alcohol-related problems over time. Screening and treatment interventions are recommended for this high-risk group to prevent further problems.
Researchers found that brain connectivity related to cognitive control predicted substance use initiation, while cognitive control behavior did not. Stronger connectivity between the dorsal anterior cingulate cortex and dorsolateral prefrontal cortex was associated with delayed substance use onset.