Articles tagged with Alcoholism
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Researchers found that brain connectivity related to cognitive control predicted substance use initiation, while cognitive control behavior did not. Stronger connectivity between the dorsal anterior cingulate cortex and dorsolateral prefrontal cortex was associated with delayed substance use onset.
A history of social isolation and alcohol use may influence how males and females respond to ketamine treatment. Female rats took ketamine more than males, while prior alcohol use increased female rat ketamine intake and changed synapse structure.
A clinical trial found that semaglutide significantly reduced weekly alcohol craving, drinking quantity, and the frequency of heavy drinking days in adults with symptoms of alcohol use disorder. Participants who received semaglutide also consumed lower amounts of alcohol during laboratory tests.
A randomized, placebo-controlled trial confirms that Ozempic reduces alcohol craving, drinking quantity and the frequency of heavy drinking days. The study found that nearly 40% of people treated with semaglutide reported no heavy drinking days in the last month of treatment.
The latest issues of APA journals bring together research on addictions, including substances and behaviors. The February issue of the American Journal of Psychiatry highlights research on addictions, while Psychiatric Services features articles on various mental health topics.
A new study from the University of Chicago Medicine challenges conventional notions about alcohol's effects in depressed people who drink excessively. Participants with AUD and depression reported feeling acute, sustained positive and rewarding alcohol effects similar to non-depressed counterparts.
A Texas A&M University researcher found that reducing alcohol consumption aligns with a harm reduction approach, which may be a more feasible approach for high-risk college drinkers. The study surveyed 822 high-risk college students and analyzed their intention to reduce drinking using the Theory of Planned Behavior.
A recent study found that people trying to quit opioids and pain medication experience more relapses compared to others. The research highlights the need for tailored treatment approaches, as some substances require more quit attempts than others.
A cluster randomized trial involving 31 Canadian high schools and 3,800 students found that delivering personality-targeted brief cognitive behavioral interventions to students in the 7th grade reduced risk for substance use disorders by the end of high school. The intervention was associated with a 23%-80% reduced odds of SUD compared...
Experts argue that the UK needs an overarching national strategy to tackle the harms caused by alcohol, with record numbers of deaths in England prompting calls for increased and sustained health funding. Sustained funding is needed for screening and care, as well as industry contribution.
A new study analyzing US data from over 27,500 participants reveals that retirees show more signs of depression than working individuals, with binge drinking exacerbating the issue. Moderate drinking appears to have fewer depressive symptoms compared to abstaining completely.
A new study reveals that more than half of US college students experience alcohol-related harms caused by others. The findings show that students who identified as White, cisfemale, or transgender, and those living with roommates, were at greater risk. Commonly reported harms included social harm, sleep disruptions, and emotional hurt.
Two studies suggest that psilocybin-assisted psychotherapy can improve mental health outcomes for patients with cancer and alcohol use disorder, reducing symptoms of anxiety, depression, and obsessive thoughts, while also promoting lasting personality changes.
A preclinical study led by Weill Cornell Medicine scientists found that estrogen surges promote binge drinking in females, causing them to 'pregame' and consume large quantities of alcohol. The study identifies a neural circuit in the brain where estrogen increases activity, leading to enhanced binge drinking behavior.
A cohort study found that nearly half of participants who consumed alcohol at baseline decreased their alcohol use after initiating anti-obesity medication treatment. The medications, such as naltrexone and glucagon-like peptide-1 receptor agonists (GLP-1 RAs), may have properties that lead to reduced cravings for alcohol.
A new study found that nearly 160 million Americans have been harmed by someone else's substance use, with 113 million experiencing harm from alcohol use and 46 million from other drugs. The survey also revealed significant overlap between the two groups, highlighting a major public health issue.
Hospitalization rates for alcohol-induced liver disease rose significantly between 2005 and 2021, with greater absolute increases among older males than younger females. The study highlights the growing burden of this condition and underscores the importance of addressing alcohol-related liver disease.
Researchers found semaglutide and liraglutide substantially decrease AUD hospitalization risk compared to approved medications. Clinical trials are needed to confirm these findings and explore their efficacy in treating AUD.
A population-based study found that alcohol use increased during the COVID-19 pandemic and was sustained post-pandemic. Stress from the pandemic and disrupted access to medical services were identified as potential causes.
A new two-year grant will support research on the intersection of alcohol use and intimate partner violence among bisexual+ young adults. The study aims to identify factors contributing to alcohol-related partner violence and inform interventions tailored to this vulnerable population.
Researchers have found that Alzheimer's disease and alcohol use disorder are associated with similar gene expression changes in the brain, including inflammation and disrupted cell signaling. This study may inform future targeted treatments for Alzheimer's and highlight the importance of considering alcohol use as a risk factor.
A new study reveals that Oriental hornets are the only animals capable of consuming high concentrations of alcohol chronically without ill effects. The research found that the hornets metabolize alcohol rapidly and show no signs of intoxication or illness, even after consuming high amounts.
A new study found that people with opioid or alcohol use disorder who take Ozempic or similar medications have a lower rate of opioid overdose and alcohol intoxication. The medication, which treats diabetes and weight-related conditions, may also alter the brain's reward-response pathways associated with substance use.
Research suggests that heavy drinkers may experience long-lasting sensitivity to mechanical stimuli, leading to permanent allodynia. The study identified a potential drug target, endocannabinoid 2-AG metabolism, for treating neuropathic pain associated with chronic and excessive alcohol consumption.
A new study by Penn State researchers found that students who feel a sense of belonging at their university are more likely to binge drink than those who do not. The study, which analyzed data from over 4,000 university students, suggests that feeling connected to the university is associated with higher rates of substance use.
Hospitalizations involving alcohol withdrawal syndrome (AWS) are a significant concern, especially in high-risk individuals. The study found that AWS burden is comparable to complications of other chronic diseases.
A new study confirms that hormonal and biochemical factors affect alcohol dependence in men and women differently, implying the need for sex-specific treatments. Researchers found associations between hormone levels and treatment outcomes, highlighting the importance of considering gender differences in treating alcoholism.
The UCR medical school is developing a new curriculum to address the substance use crisis in California, which has resulted in over 6,000 opioid-related overdose deaths. The curriculum aims to promote access to treatment and health equity for substance use care, addressing biases and social determinants of health.
A new study finds that four unhealthy behaviors, including smoking and physical inactivity, contribute significantly to socioeconomic disparities in coronary artery disease mortality. The researchers conclude that targeted public health policies can help reduce these disparities and improve heart health for low-income individuals.
A study from University of Gothenburg links work-related pain to mental illness among construction workers. Managers' empathetic or neglectful attitudes are highlighted as key factors in mental health.
A new special series of articles in the Journal of Studies on Alcohol and Drugs highlights the potential of psychedelic-assisted therapy for treating alcohol dependence, opioid addiction, and other substance use disorders. Promising results suggest that this approach can lead to higher abstinence rates than conventional therapy alone.
A UK cohort study reveals that even low-risk alcohol consumption is linked to increased mortality among older adults with health-related or socioeconomic risk factors. The findings suggest that healthier lifestyles may play a role in the observed attenuation of mortality for wine drinkers and those who drink only during meals.
A UTEP study using fruit flies reveals that social settings enhance the stimulant effect of ethanol, linked to increased activity in the D1 dopamine receptor. This finding may lead to a better understanding of Alcohol Use Disorder and its vulnerability to social influences.
A national research study found that a lack of institutional support is the top reason doctors are reluctant to discuss addiction with their patients. The study also highlighted knowledge and skill gaps as significant barriers to delivering evidence-based interventions.
Two studies shed light on alcohol consumption and its negative impact on heart function in women taking estrogen replacement therapy. Researchers found that abstinence from alcohol can prevent most alcohol-associated risks of atrial fibrillation, highlighting the potential for new anti-AFib strategies.
A new University of Georgia study reveals that one in five US farmers report binge drinking when they experience high levels of stress. The survey also found that farmers consume alcohol at similar rates as the general public, but those who reported feeling supported by community resources were less likely to drink excessively.
Scripps Research scientists have identified the posterior paraventricular nucleus of the thalamus as a key brain region involved in stress-induced oxycodone relapse. Exposure to suvorexant, which blocks orexin signaling, reduced drug-seeking behavior and prevented relapse.
Rural residents with head and neck cancer experience higher mortality rates due to factors like alcohol use, tobacco consumption, and lower HPV vaccination rates. This disparity widens the rural-urban mortality gap.
Researchers discovered that sodium valerate supplementation can dramatically reduce binge drinking behavior and blood ethanol concentration in mice. The study highlights the potential therapeutic role of sodium valerate in reducing excessive alcohol use.
A new study reveals six drinking patterns in Europe, with countries like Estonia and Cyprus showing the highest average alcohol-attributable deaths. The research suggests that changing these patterns requires a cultural shift and may involve implementing effective alcohol policies.
A significant number of Australian women (over 300,000) are drinking at very high-risk levels, with a greater proportion of men consuming alcohol at similar rates. Women are more susceptible to health problems from excessive drinking and may be affected by their natural biological rhythms.
A recent study found that the combination of alcohol and cabin pressure during long-haul flights can lower blood oxygen levels and raise heart rates, even in young and healthy individuals. The researchers suggest that restricting access to alcohol on board may be necessary to protect passenger heart health.
A new study by Carnegie Mellon University found that young adults who were heavy drinkers before the pandemic reduced their alcohol consumption significantly during and after the pandemic. The study also showed a decrease in negative emotions and no change in using alcohol as a coping mechanism.
Research using 2011-2021 data found limited associations between recreational cannabis legalization and adolescent substance use. Recreational cannabis retail sales were linked to lower e-cigarette use and an increased frequency of cannabis use among users, leading to no overall change in cannabis use.
Midlife mortality rates for deaths of despair, including suicide, overdose, and liver disease, vary by race and ethnicity, with higher rates among Black and American Indian/Alaska Native populations. Early mortality from drug- and alcohol-related causes contributes to these disparities.
Research analyzed genetic data from 3 million individuals and found connections between gene variants influencing alcohol use and many non-alcohol-related conditions. Individuals with protective alleles had better health but also worse outcomes in certain areas, such as tobacco use and skin cancer.
A recent survey study reveals binge drinking is more prevalent among sports wagering individuals compared to nongamblers and non–sports gamblers. This finding highlights the need for targeted interventions to address excessive alcohol consumption in this demographic.
A new study found that shortening overnight operations at bars and taverns reduced homicides by 51% within the first month and by 40% annually. Reducing late-night alcohol sales also decreased all violent crimes by 23% annually in a Baltimore neighborhood.
Researchers have found that LY2444296, a compound blocking the kappa opioid receptor, significantly reduced withdrawal symptoms and alcohol consumption in rats with alcohol dependence. The study suggests that blocking this receptor could lead to new treatment options for people experiencing alcohol use disorder.
A large study found that drinking more than one drink per day can increase the risk of coronary heart disease, especially among young to middle-aged women. The risk was highest among those who engaged in binge drinking, with women facing a 68% higher risk compared to moderate drinkers.
A systematic review and meta-analysis found a strong association between alcohol use disorder and suicide mortality across genders. The study highlights the importance of addressing alcohol use disorder as part of comprehensive suicide prevention strategies.
A recent study by Flinders University found that parents are conflicted and concerned about zero-alcohol drinks due to their similarity in taste and appearance. The research suggests that providing these drinks to adolescents may normalize alcohol consumption, leading to increased risks of harm.
A survey study reveals primary care pediatricians lack preparedness in managing adolescent OUD, with a notable gap compared to other substance use disorders. The results underscore the importance of workforce training programs to address this critical healthcare issue.
A new study has found that heavy alcohol use and illicit opioid use are linked to a higher risk of falls and fractures among people living with HIV. The study suggests the need for targeted clinical screening and interventions to prevent falls and related injuries, particularly among populations already at risk.
The University of Pittsburgh School of Pharmacy's PERU has received a $7.8 million grant to develop and implement measurement-based care into community opioid treatment programs across Pennsylvania. This project aims to improve treatment access, promote recovery, and reduce fatal overdoses by addressing patient needs through personaliz...
A new study found that African Americans, Hispanics/Latinx, and young adults are less likely to attend Alcoholics Anonymous meetings compared to White counterparts. The study also found that these disparities have persisted despite the evolution of AA and the availability of alternative mutual-help groups.
A study by University of Georgia researchers found female farmers report higher levels of stress and are more likely to binge drink when they do consume alcohol. The pattern holds true for those who own or manage farms, where women face unique challenges in male-dominated industries.
A new study by Staffordshire University has found that stigma in drug and alcohol treatment services can lead to emotional harm for women. The research reveals that women are often stigmatised and shamed when seeking support from professionals.
A new study suggests that using artificial intelligence to scan surgery patients' medical records can identify those with risky drinking habits who may benefit from education or treatment. The AI system analyzed over 53,000 patient records and found three times more patients with high-risk alcohol use than diagnosis codes alone.
Researchers found that reducing stimulant use was associated with significant improvement in measures of health and recovery among people with stimulant use disorder. This suggests that a more nuanced perspective on measuring treatment success may be beneficial.