Articles tagged with Alcoholism
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A study from Boston University School of Medicine identifies pituitary adenylate cyclase activating polypeptide (PACAP) as a critical player in heavy alcohol consumption. PACAP's action in the brain's bed nucleus of the stria terminalis (BNST) region is found to be linked to increased stress responses and excessive drinking behavior.
A new study published in Cannabis and Cannabinoids Research found that 12% of people aged 50-80 have consumed a THC-containing substance in the past year. Those who drink alcohol at risky levels have a higher rate of cannabis use, highlighting the need for education and screening for older adults.
A new study identified 60 alcohol-associated circulating metabolites that appear to produce counteractive effects on the risk of heart disease. The findings suggest that moderate alcohol consumption may trigger changes in metabolomic profiles, yielding both beneficial and harmful outcomes.
Recent research from the University of Southern Denmark suggests that even modest reductions in alcohol consumption and participation in treatment can improve quality of life for older adults aged 60 and above with notable alcohol intake. A study utilizing data from the Elderly Study found significant improvements across all domains, i...
Researchers tested EMDR, a therapy proven to treat PTSD and depression, to reduce addiction cravings. The study found Addiction-focused EMDR was as effective as cognitive behavioral therapy for cravings, reducing symptoms by clinically significant amounts.
Researchers found that changes in voice patterns predicted alcohol intoxication with 98% accuracy. The study suggests that smartphones and smart speakers could be used to deliver 'just-in-time interventions' to prevent injuries and deaths from motor vehicle accidents.
The new Canadian guideline aims to reduce harms associated with high-risk drinking and support people's treatment and recovery from AUD. It provides 15 evidence-based recommendations for primary health care providers to implement effective screening and treatment interventions.
A Swedish study finds that fathers' parental leave is associated with a 34% decrease in alcohol-related hospitalizations among fathers, as well as smaller decreases over time. The policy change led to increased fathers' use of parental leave, which may explain the observed health benefits.
A study of 69,000 adults with hepatitis C virus (HCV) infection found no difference in sustained virologic response across alcohol use categories. This suggests that restricting access to direct-acting antiviral therapy based on alcohol use may create unnecessary barriers for patients. The findings challenge HCV elimination goals.
A new NIH grant will investigate the impact of combined alcohol and e-cigarette use on the blood brain barrier, a cell layer regulating substance passage into the central nervous system. The study aims to identify mechanisms behind damage and potential biomarkers for clinical use.
A $3 million grant will support a culturally tailored group-based intervention to prevent alcohol addiction and consequences in Pacific Islander young adults. The study aims to address the extreme risk of alcohol abuse in this population, which has been linked to high rates of alcohol use disorder.
Children born to parents with substance use disorders are at increased risk of intellectual disability, regardless of whether the issue is with mothers or fathers. The study found that both genetic and environmental factors may contribute to this risk.
A neglected brain region has been identified as a key player in addiction recovery. The supplementary motor cortex was found to be hyperexcitable in individuals with cocaine use disorders, even after withdrawal periods of 45 days. This discovery may lead to new treatment approaches using transcranial magnetic stimulation.
Researchers found a significant increase in pediatric trauma admissions during the COVID-19 pandemic, with younger patients and falls from moderate heights being more common. Blood alcohol levels were also higher in patients aged 14-18 years old, suggesting targeted interventions to curb alcohol use may be needed
Researchers have discovered that gene therapy may prevent relapse in patients with serious alcohol addiction by altering dopamine function in the brain's mesolimbic reward pathway. The treatment involves sustained release of glial-derived neurotrophic factor (GDNF) in a specific region of the brain.
Researchers at Oregon Health & Science University have found that implanting a specific molecule in the brain can effectively reduce alcohol use among chronic heavy drinkers. The study showed a 90% reduction in drinking behavior in nonhuman primates, with the implanted virus permanently increasing dopamine levels and reducing cravings.
A study of 15,000 adults found that alcohol consumption and risky drinking behaviors were prevalent among cancer survivors. The findings highlight the need for additional research to address the emerging concern of alcohol consumption in cancer patients.
A recent study found a significantly higher rate of increase in deaths among female individuals due to alcohol-related causes. The findings underscore the importance of investigating specific factors contributing to this trend.
Researchers found that Korean Red Ginseng (KRG) can restore spatial working memory and reduce withdrawal symptoms in mice exposed to alcohol. KRG suppresses the PKA-CREB signaling pathway and inhibits neuroinflammation, suggesting its potential as a novel therapeutic intervention for treating alcohol use disorder.
A study published in Alcohol: Clinical and Experimental Research found that a group of genes involved in neuronal plasticity and pain perception are also associated with alcohol use disorder (AUD) risk. These genes work together to influence neural communication, leading to changes in brain function that can contribute to AUDs.
A study by Dr. Mary Beth Miller found that cognitive behavioral therapy (CBT) for insomnia effectively reduced negative outcomes associated with excessive drinking among veterans. CBT improved insomnia symptoms, which in turn decreased cravings and negative behaviors related to alcohol consumption.
Researchers at Texas A&M University found that substance use impairs cognitive flexibility by inhibiting specific neurons. Chronic cocaine or alcohol use alters the local inhibitory brain circuit, leading to decreased cognitive flexibility and increased risk of academic deficits and lower quality of life.
Researchers found that individuals with AUD displayed less impairment on fine motor and cognitive tasks when consuming a standard dose of alcohol, but showed significant impairment at a higher dose. This suggests that the physical effects of alcohol accumulation contribute to impaired performance beyond mere tolerance.
Research at Columbia University Mailman School of Public Health found a rise in binge drinking among people aged 31 and over in US states with recreational cannabis laws. Binge drinking declined among younger age groups, including those aged 12-20 and 21-30.
A study found that harm reduction treatment reduced substance use, including cannabis and polysubstance use, among people experiencing homelessness. Participants in the treatment group used cannabis 41% fewer days than the control group. The approach led to improved quality of life and basic needs, making it a sustainable option.
Young adults with a history of heavy drinking since adolescence exhibit lower cortical gray matter thickness and altered neurotransmission, according to a recent study. Cortical thinning is associated with increased inhibitory neurotransmission, especially in the frontal and parietal lobes.
A study by Scripps Research and University of Bologna found that excessive alcohol consumption accelerates cognitive decline in genetically susceptible mice. Gene expression analysis revealed widespread changes indicative of disease progression, including increased neuronal excitability and neurodegeneration.
A study published in The Lancet Psychiatry found that adolescents with signs of alcohol dependence are more likely to develop depression by their mid-20s. This association remained after adjusting for potential confounding factors, suggesting a causal relationship between alcohol dependence and subsequent depression.
Researchers found that individuals understood genetic risk scores and reported intentions to reduce their drinking if they had high-risk scores. However, the study's authors caution that receiving genetic feedback is just the first step in behavior change, and connecting individuals to resources and support is crucial.
A recent study published in Calcified Tissue International found that heavy drinkers are at risk of muscle loss and frailty. The research, which analyzed data from the UK Biobank, suggests that consuming 10 units or more of alcohol per day can lead to lower muscle mass, even when adjusted for body size and other factors.
A new national study of over 50,000 US adolescents reveals a strong association between vaping nicotine and increased likelihood of high-level cannabis usage and binge drinking. The findings highlight the need for sustained interventions to address co-occurring substance use among young people.
Researchers found people with anxiety and depression disorder experience greater alcohol use disorder symptoms, even at similar levels of drinking. The study analyzed data on 26,000 adults and found that those with internalizing disorders predicted more alcohol-related symptoms.
A study of working men in Japan, Taiwan, and South Korea found that alcohol-tolerant individuals do not earn more than their intolerant colleagues. Despite the cultural pressure to drink, better social drinkers did not experience a wage premium in terms of working hours or earnings.
A Scripps Research team found that both alcohol intake and withdrawal can lead to increased pain sensitivity in adult mice. The study suggests potential new drug targets for treating alcohol-associated chronic pain and hypersensitivity.
A new Northwestern Medicine study found that only 7% of Medicaid enrollees with opioid use disorder (OUD) received residential treatment, highlighting a significant gap in care. Residential treatment centers provide structured support and are considered one of the best treatments for severe substance use.
A randomized trial found tailored education and peer support significantly reduced binge-drinking among Army National Guard members over the course of a year. Participants who received online education sessions and supportive phone calls from veteran peers showed substantial declines in binge-drinking days and scores on risk assessments.
Research finds that endocannabinoids protect against addiction in individuals exposed to childhood maltreatment. The 'resilient' group showed increased function of the endocannabinoid system and different brain activity compared to other groups.
Researchers found that alcohol screening rates significantly declined during the initial COVID-19 surge due to competing pandemic priorities and telemedicine shifts. Screening rates later recovered as in-person care resumed and telemedicine workflows improved.
A Marshall University researcher has received a $388,500 NIH grant to study the effects of binge drinking on brain development and its long-term cognitive consequences. The two-year grant will allow her team to identify mechanisms that drive changes in brain function and explore novel targets for prevention and treatment.
A comprehensive study found that individuals who maintained their drinking habits during the pandemic had lower prevalence of mental health issues compared to those who abstained or experienced changes. The research also identified groups with stronger associations between alcohol consumption and mental health outcomes.
A systematic review and meta-analysis of 4.8 million participants found no significant association between daily low or moderate alcohol intake and all-cause mortality risk. However, increased risk was evident at higher consumption levels, starting at lower levels for women than men.
A recent study found that heavy alcohol use changes signaling pathways in the brain, affecting cognitive functions like decision-making and impulse control. The mechanism involves the brain's immune system and the molecule interleukin 1β, which regulates inflammation and neurotransmitter release.
A CAMH-led study found that the probability of using a gun as a means of suicide among Americans increases with alcohol consumption. The study suggests that responsible gun ownership and awareness of alcohol's increased risk are crucial in preventing gun-involved suicides.
A study found that as alcohol consumption increased, the probability of a firearm-involved suicide also rose until a certain blood alcohol concentration was reached. Interventions focusing on heavy alcohol use may help reduce suicide mortality rates, particularly those involving firearms.
A new LSU Health New Orleans study suggests that single, focused Interprofessional Education-based exercises can significantly decrease stigma associated with alcohol use and improve knowledge and confidence in screening for Alcohol Use Disorder (AUD). The exercise led to substantial improvements in student understanding of AUD risks, ...
Researchers found that peer support specialists with a shared life experience were most valued for providing emotional and housing/employment support, helping inmates recover from opioid use disorder. Participants appreciated the empathetic and trustworthy relationships established with their peer navigators.
A new study published in BMC Public Health suggests that problematic social media use in preteens is linked to both positive and negative alcohol beliefs. Researchers found that 97% of social media posts display alcohol in a positive context, contributing to positive perceptions among adolescents.
A Scripps Research team has found that heavy alcohol consumption increases brain inflammation, leading to changes in signaling pathways and behavior. The study suggests a potential new drug target for treating alcohol use disorder by targeting the interleukin-1β pathway.
A CAMH-led study examines national suicide rates in 33 countries over 20 years, identifying eight population-level factors associated with suicide rates. The study highlights the importance of considering gender differences when developing suicide risk reduction initiatives.
Researchers identified apremilast as an incredibly promising treatment for alcohol use disorder, reducing consumption by more than half in a clinical trial. The medication, approved for psoriasis and psoriatic arthritis, triggers increased activity in the brain's nucleus accumbens to control alcohol intake.
Researchers at Kyoto University found distinct patterns of gazing and brain activity in patients with kleptomania when shown relevant environmental cues. These results suggest a similar mechanism to drug addiction, potentially leading to the development of therapeutic treatments.
Researchers have identified a blood protein snapshot that documents changes in patients with severe liver disease caused by heavy drinking, potentially leading to a simple blood test for diagnosis and treatment monitoring.
A large study of 2.8 million patients found no direct link between SARS-CoV-2 infection and new-onset alcohol use disorder, suggesting other factors at play during the pandemic
A new study found that individuals with a strong sense of purpose in life are less likely to drink heavily when craving alcohol. This discovery opens the door for new strategies to discourage binge drinking in college students by focusing on their mission, values, and goals.
Researchers found that MAP4343 reversed excessive alcohol intake in mice modeling alcoholism and normalized blood levels of stress hormone corticosterone. The compound promotes assembly of tubulin proteins into microtubules, suggesting a possible effective treatment strategy for alcohol use disorder.
A study of 4,000 twins found no link between cannabis legalization and increases in cognitive, psychological, social, relationship or financial problems. Twins in states where cannabis is legal showed fewer symptoms of alcohol use disorder.
A new study explores the relationship between fatty acid amide hydrolase (FAAH) levels and heavy drinking patterns in young adults. Lower FAAH activity was associated with more severe drinking, increased cravings, and reduced sensitivity to alcohol's negative effects.
Researchers have discovered the positive impact of icaros on men's recovery from drug and alcohol addictions during ayahuasca healing ceremonies. The study, led by UC Riverside doctoral student Owain J. Graham, found that 86% of patients showed statistically significant improvements on the Addictions Severity Index.
A new paper in Nature Reviews Disease Primers provides a global overview of hazardous drinking and alcohol use disorders, highlighting current approaches to diagnosis, screening, prevention, management, and treatment. The study emphasizes the need for further research, particularly on adolescents and effective behavioral interventions.
A new NIH-funded study found a significant treatment gap for individuals with both hepatitis C and alcohol use disorder, highlighting the need for better care coordination. Researchers analyzed data from over 133,000 veterans and found that those with AUD were less likely to receive direct-acting antiviral treatment for HCV.