A new special series of articles in the Journal of Studies on Alcohol and Drugs highlights the potential of psychedelic-assisted therapy for treating alcohol dependence, opioid addiction, and other substance use disorders. Promising results suggest that this approach can lead to higher abstinence rates than conventional therapy alone.
SourceJournal of Studies on Alcohol and Drugs·JournalJournal of Studies on Alcohol and Drugs·TypeLiterature review·DateAug 26, 2024
A UK cohort study reveals that even low-risk alcohol consumption is linked to increased mortality among older adults with health-related or socioeconomic risk factors. The findings suggest that healthier lifestyles may play a role in the observed attenuation of mortality for wine drinkers and those who drink only during meals.
SourceJAMA Network·JournalJAMA Network Open·DateAug 12, 2024
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A UTEP study using fruit flies reveals that social settings enhance the stimulant effect of ethanol, linked to increased activity in the D1 dopamine receptor. This finding may lead to a better understanding of Alcohol Use Disorder and its vulnerability to social influences.
SourceUniversity of Texas at El Paso·JournalAddiction Biology·DateAug 6, 2024
A national research study found that a lack of institutional support is the top reason doctors are reluctant to discuss addiction with their patients. The study also highlighted knowledge and skill gaps as significant barriers to delivering evidence-based interventions.
SourceUniversity of Colorado Anschutz Medical Campus·JournalJAMA Network Open·DateJul 30, 2024
Two studies shed light on alcohol consumption and its negative impact on heart function in women taking estrogen replacement therapy. Researchers found that abstinence from alcohol can prevent most alcohol-associated risks of atrial fibrillation, highlighting the potential for new anti-AFib strategies.
A new University of Georgia study reveals that one in five US farmers report binge drinking when they experience high levels of stress. The survey also found that farmers consume alcohol at similar rates as the general public, but those who reported feeling supported by community resources were less likely to drink excessively.
SourceUniversity of Georgia·JournalJournal of Agromedicine·DateJul 16, 2024
Scripps Research scientists have identified the posterior paraventricular nucleus of the thalamus as a key brain region involved in stress-induced oxycodone relapse. Exposure to suvorexant, which blocks orexin signaling, reduced drug-seeking behavior and prevented relapse.
SourceScripps Research Institute·JournalJournal of Psychopharmacology·DateJul 9, 2024
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Rural residents with head and neck cancer experience higher mortality rates due to factors like alcohol use, tobacco consumption, and lower HPV vaccination rates. This disparity widens the rural-urban mortality gap.
SourceJAMA Network·JournalJAMA Otolaryngology–Head & Neck Surgery·DateJun 27, 2024
Researchers discovered that sodium valerate supplementation can dramatically reduce binge drinking behavior and blood ethanol concentration in mice. The study highlights the potential therapeutic role of sodium valerate in reducing excessive alcohol use.
SourceJackson Laboratory·JournalMicrobiome·TypeExperimental study·DateJun 25, 2024
A new study reveals six drinking patterns in Europe, with countries like Estonia and Cyprus showing the highest average alcohol-attributable deaths. The research suggests that changing these patterns requires a cultural shift and may involve implementing effective alcohol policies.
SourceSociety for the Study of Addiction·JournalAddiction·TypeData/statistical analysis·DateJun 24, 2024
A significant number of Australian women (over 300,000) are drinking at very high-risk levels, with a greater proportion of men consuming alcohol at similar rates. Women are more susceptible to health problems from excessive drinking and may be affected by their natural biological rhythms.
SourceFlinders University·JournalDrug and Alcohol Review·TypeSystematic review·DateJun 20, 2024
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A recent study found that the combination of alcohol and cabin pressure during long-haul flights can lower blood oxygen levels and raise heart rates, even in young and healthy individuals. The researchers suggest that restricting access to alcohol on board may be necessary to protect passenger heart health.
SourceBMJ Group·JournalThorax·TypeRandomized controlled/clinical trial·DateJun 3, 2024
A new study by Carnegie Mellon University found that young adults who were heavy drinkers before the pandemic reduced their alcohol consumption significantly during and after the pandemic. The study also showed a decrease in negative emotions and no change in using alcohol as a coping mechanism.
SourceCarnegie Mellon University·JournalNature Mental Health·TypeObservational study·DateMay 2, 2024
Research using 2011-2021 data found limited associations between recreational cannabis legalization and adolescent substance use. Recreational cannabis retail sales were linked to lower e-cigarette use and an increased frequency of cannabis use among users, leading to no overall change in cannabis use.
Midlife mortality rates for deaths of despair, including suicide, overdose, and liver disease, vary by race and ethnicity, with higher rates among Black and American Indian/Alaska Native populations. Early mortality from drug- and alcohol-related causes contributes to these disparities.
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Research analyzed genetic data from 3 million individuals and found connections between gene variants influencing alcohol use and many non-alcohol-related conditions. Individuals with protective alleles had better health but also worse outcomes in certain areas, such as tobacco use and skin cancer.
SourceUniversity of California - San Diego·JournalEBioMedicine·DateApr 5, 2024
A new study found that shortening overnight operations at bars and taverns reduced homicides by 51% within the first month and by 40% annually. Reducing late-night alcohol sales also decreased all violent crimes by 23% annually in a Baltimore neighborhood.
SourceBoston University School of Public Health·JournalJAMA Internal Medicine·TypeObservational study·DateApr 1, 2024
A recent survey study reveals binge drinking is more prevalent among sports wagering individuals compared to nongamblers and non–sports gamblers. This finding highlights the need for targeted interventions to address excessive alcohol consumption in this demographic.
SourceJAMA Network·JournalJAMA Network Open·DateApr 1, 2024
Researchers have found that LY2444296, a compound blocking the kappa opioid receptor, significantly reduced withdrawal symptoms and alcohol consumption in rats with alcohol dependence. The study suggests that blocking this receptor could lead to new treatment options for people experiencing alcohol use disorder.
SourceScripps Research Institute·JournalScientific Reports·DateMar 29, 2024
A large study found that drinking more than one drink per day can increase the risk of coronary heart disease, especially among young to middle-aged women. The risk was highest among those who engaged in binge drinking, with women facing a 68% higher risk compared to moderate drinkers.
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A systematic review and meta-analysis found a strong association between alcohol use disorder and suicide mortality across genders. The study highlights the importance of addressing alcohol use disorder as part of comprehensive suicide prevention strategies.
SourceJAMA Network·JournalJAMA Network Open·DateMar 12, 2024
A recent study by Flinders University found that parents are conflicted and concerned about zero-alcohol drinks due to their similarity in taste and appearance. The research suggests that providing these drinks to adolescents may normalize alcohol consumption, leading to increased risks of harm.
SourceFlinders University·JournalAustralian and New Zealand Journal of Public Health·TypeSurvey·DateMar 4, 2024
A survey study reveals primary care pediatricians lack preparedness in managing adolescent OUD, with a notable gap compared to other substance use disorders. The results underscore the importance of workforce training programs to address this critical healthcare issue.
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A new study has found that heavy alcohol use and illicit opioid use are linked to a higher risk of falls and fractures among people living with HIV. The study suggests the need for targeted clinical screening and interventions to prevent falls and related injuries, particularly among populations already at risk.
SourceBoston University School of Public Health·JournalJAIDS Journal of Acquired Immune Deficiency Syndromes·TypeObservational study·DateFeb 21, 2024
The University of Pittsburgh School of Pharmacy's PERU has received a $7.8 million grant to develop and implement measurement-based care into community opioid treatment programs across Pennsylvania. This project aims to improve treatment access, promote recovery, and reduce fatal overdoses by addressing patient needs through personaliz...
A study by University of Georgia researchers found female farmers report higher levels of stress and are more likely to binge drink when they do consume alcohol. The pattern holds true for those who own or manage farms, where women face unique challenges in male-dominated industries.
SourceUniversity of Georgia·JournalJournal of Occupational and Environmental Medicine·DateJan 24, 2024
A new study found that African Americans, Hispanics/Latinx, and young adults are less likely to attend Alcoholics Anonymous meetings compared to White counterparts. The study also found that these disparities have persisted despite the evolution of AA and the availability of alternative mutual-help groups.
SourceJournal of Studies on Alcohol and Drugs·JournalJournal of Studies on Alcohol and Drugs·TypeSurvey·DateJan 24, 2024
A new study by Staffordshire University has found that stigma in drug and alcohol treatment services can lead to emotional harm for women. The research reveals that women are often stigmatised and shamed when seeking support from professionals.
SourceStaffordshire University·JournalInternational Journal of Environmental Research and Public Health·TypeSurvey·DateJan 19, 2024
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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A new study suggests that using artificial intelligence to scan surgery patients' medical records can identify those with risky drinking habits who may benefit from education or treatment. The AI system analyzed over 53,000 patient records and found three times more patients with high-risk alcohol use than diagnosis codes alone.
SourceMichigan Medicine - University of Michigan·JournalAlcohol Clinical and Experimental Research·TypeData/statistical analysis·DateJan 12, 2024
Researchers found that reducing stimulant use was associated with significant improvement in measures of health and recovery among people with stimulant use disorder. This suggests that a more nuanced perspective on measuring treatment success may be beneficial.
SourceNIH/National Institute on Drug Abuse·JournalAddiction·DateJan 10, 2024
A study from Boston University School of Medicine identifies pituitary adenylate cyclase activating polypeptide (PACAP) as a critical player in heavy alcohol consumption. PACAP's action in the brain's bed nucleus of the stria terminalis (BNST) region is found to be linked to increased stress responses and excessive drinking behavior.
SourceBoston University School of Medicine·JournaleNeuro·TypeExperimental study·DateDec 1, 2023
A new study published in Cannabis and Cannabinoids Research found that 12% of people aged 50-80 have consumed a THC-containing substance in the past year. Those who drink alcohol at risky levels have a higher rate of cannabis use, highlighting the need for education and screening for older adults.
SourceMichigan Medicine - University of Michigan·JournalCannabis and Cannabinoid Research·TypeSurvey·DateDec 1, 2023
A new study identified 60 alcohol-associated circulating metabolites that appear to produce counteractive effects on the risk of heart disease. The findings suggest that moderate alcohol consumption may trigger changes in metabolomic profiles, yielding both beneficial and harmful outcomes.
SourceBoston University School of Public Health·JournalBMC Medicine·TypeData/statistical analysis·DateNov 28, 2023
Aranet4 Home CO2 Monitor
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Recent research from the University of Southern Denmark suggests that even modest reductions in alcohol consumption and participation in treatment can improve quality of life for older adults aged 60 and above with notable alcohol intake. A study utilizing data from the Elderly Study found significant improvements across all domains, i...
SourceUniversity of Southern Denmark Faculty of Health Sciences·JournalAlcohol Clinical and Experimental Research·TypeRandomized controlled/clinical trial·DateNov 17, 2023
Researchers tested EMDR, a therapy proven to treat PTSD and depression, to reduce addiction cravings. The study found Addiction-focused EMDR was as effective as cognitive behavioral therapy for cravings, reducing symptoms by clinically significant amounts.
SourceFlorida Atlantic University·JournalJournal of Evidence-Based Social Work·TypeExperimental study·DateNov 14, 2023
Researchers found that changes in voice patterns predicted alcohol intoxication with 98% accuracy. The study suggests that smartphones and smart speakers could be used to deliver 'just-in-time interventions' to prevent injuries and deaths from motor vehicle accidents.
SourceJournal of Studies on Alcohol and Drugs·JournalJournal of Studies on Alcohol and Drugs·TypeExperimental study·DateNov 9, 2023
The new Canadian guideline aims to reduce harms associated with high-risk drinking and support people's treatment and recovery from AUD. It provides 15 evidence-based recommendations for primary health care providers to implement effective screening and treatment interventions.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·TypeLiterature review·DateOct 16, 2023
A Swedish study finds that fathers' parental leave is associated with a 34% decrease in alcohol-related hospitalizations among fathers, as well as smaller decreases over time. The policy change led to increased fathers' use of parental leave, which may explain the observed health benefits.
SourceStockholm University·JournalAddiction·TypeObservational study·DateOct 6, 2023
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A study of 69,000 adults with hepatitis C virus (HCV) infection found no difference in sustained virologic response across alcohol use categories. This suggests that restricting access to direct-acting antiviral therapy based on alcohol use may create unnecessary barriers for patients. The findings challenge HCV elimination goals.
SourceJAMA Network·JournalJAMA Network Open·DateSep 26, 2023
A new NIH grant will investigate the impact of combined alcohol and e-cigarette use on the blood brain barrier, a cell layer regulating substance passage into the central nervous system. The study aims to identify mechanisms behind damage and potential biomarkers for clinical use.
A $3 million grant will support a culturally tailored group-based intervention to prevent alcohol addiction and consequences in Pacific Islander young adults. The study aims to address the extreme risk of alcohol abuse in this population, which has been linked to high rates of alcohol use disorder.
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Children born to parents with substance use disorders are at increased risk of intellectual disability, regardless of whether the issue is with mothers or fathers. The study found that both genetic and environmental factors may contribute to this risk.
SourceKarolinska Institutet·JournalEClinicalMedicine·TypeObservational study·DateSep 7, 2023
A neglected brain region has been identified as a key player in addiction recovery. The supplementary motor cortex was found to be hyperexcitable in individuals with cocaine use disorders, even after withdrawal periods of 45 days. This discovery may lead to new treatment approaches using transcranial magnetic stimulation.
SourceIndiana University School of Medicine·JournalBiological Psychiatry·DateAug 24, 2023
Researchers found a significant increase in pediatric trauma admissions during the COVID-19 pandemic, with younger patients and falls from moderate heights being more common. Blood alcohol levels were also higher in patients aged 14-18 years old, suggesting targeted interventions to curb alcohol use may be needed
SourceCactus Communications·JournalPediatric Investigation·TypeData/statistical analysis·DateAug 23, 2023
Researchers have discovered that gene therapy may prevent relapse in patients with serious alcohol addiction by altering dopamine function in the brain's mesolimbic reward pathway. The treatment involves sustained release of glial-derived neurotrophic factor (GDNF) in a specific region of the brain.
SourceOhio State University Wexner Medical Center·JournalNature Medicine·TypeRandomized controlled/clinical trial·DateAug 14, 2023
Researchers at Oregon Health & Science University have found that implanting a specific molecule in the brain can effectively reduce alcohol use among chronic heavy drinkers. The study showed a 90% reduction in drinking behavior in nonhuman primates, with the implanted virus permanently increasing dopamine levels and reducing cravings.
SourceOregon Health & Science University·JournalNature Medicine·TypeExperimental study·DateAug 14, 2023
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A study of 15,000 adults found that alcohol consumption and risky drinking behaviors were prevalent among cancer survivors. The findings highlight the need for additional research to address the emerging concern of alcohol consumption in cancer patients.
SourceJAMA Network·JournalJAMA Network Open·DateAug 10, 2023
A recent study found a significantly higher rate of increase in deaths among female individuals due to alcohol-related causes. The findings underscore the importance of investigating specific factors contributing to this trend.
SourceJAMA Network·JournalJAMA Network Open·DateJul 28, 2023
Researchers found that Korean Red Ginseng (KRG) can restore spatial working memory and reduce withdrawal symptoms in mice exposed to alcohol. KRG suppresses the PKA-CREB signaling pathway and inhibits neuroinflammation, suggesting its potential as a novel therapeutic intervention for treating alcohol use disorder.
SourceSahmyook University·JournalJournal of Ginseng Research·TypeExperimental study·DateJul 26, 2023
A study published in Alcohol: Clinical and Experimental Research found that a group of genes involved in neuronal plasticity and pain perception are also associated with alcohol use disorder (AUD) risk. These genes work together to influence neural communication, leading to changes in brain function that can contribute to AUDs.
SourceIndiana University School of Medicine·JournalAlcoholism Clinical and Experimental Research·DateJul 17, 2023
A study by Dr. Mary Beth Miller found that cognitive behavioral therapy (CBT) for insomnia effectively reduced negative outcomes associated with excessive drinking among veterans. CBT improved insomnia symptoms, which in turn decreased cravings and negative behaviors related to alcohol consumption.
SourceUniversity of Missouri-Columbia·JournalJAMA Psychiatry·TypeRandomized controlled/clinical trial·DateJul 12, 2023
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Researchers at Texas A&M University found that substance use impairs cognitive flexibility by inhibiting specific neurons. Chronic cocaine or alcohol use alters the local inhibitory brain circuit, leading to decreased cognitive flexibility and increased risk of academic deficits and lower quality of life.
SourceTexas A&M University·JournalNature Communications·DateJul 11, 2023
Researchers found that individuals with AUD displayed less impairment on fine motor and cognitive tasks when consuming a standard dose of alcohol, but showed significant impairment at a higher dose. This suggests that the physical effects of alcohol accumulation contribute to impaired performance beyond mere tolerance.
SourceUniversity of Chicago·JournalAlcoholism Clinical and Experimental Research·TypeRandomized controlled/clinical trial·DateJun 18, 2023
Research at Columbia University Mailman School of Public Health found a rise in binge drinking among people aged 31 and over in US states with recreational cannabis laws. Binge drinking declined among younger age groups, including those aged 12-20 and 21-30.
SourceColumbia University's Mailman School of Public Health·JournalInternational Journal of Drug Policy·DateJun 15, 2023
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A study found that harm reduction treatment reduced substance use, including cannabis and polysubstance use, among people experiencing homelessness. Participants in the treatment group used cannabis 41% fewer days than the control group. The approach led to improved quality of life and basic needs, making it a sustainable option.
SourceWashington State University·JournalJournal of Addiction Medicine·DateJun 14, 2023
A study by Scripps Research and University of Bologna found that excessive alcohol consumption accelerates cognitive decline in genetically susceptible mice. Gene expression analysis revealed widespread changes indicative of disease progression, including increased neuronal excitability and neurodegeneration.
SourceScripps Research Institute·JournaleNeuro·DateJun 12, 2023
Young adults with a history of heavy drinking since adolescence exhibit lower cortical gray matter thickness and altered neurotransmission, according to a recent study. Cortical thinning is associated with increased inhibitory neurotransmission, especially in the frontal and parietal lobes.
SourceUniversity of Eastern Finland·JournalAlcoholism Clinical and Experimental Research·DateJun 12, 2023
A study published in The Lancet Psychiatry found that adolescents with signs of alcohol dependence are more likely to develop depression by their mid-20s. This association remained after adjusting for potential confounding factors, suggesting a causal relationship between alcohol dependence and subsequent depression.
SourceUniversity College London·JournalThe Lancet Psychiatry·TypeObservational study·DateJun 1, 2023
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Researchers found that individuals understood genetic risk scores and reported intentions to reduce their drinking if they had high-risk scores. However, the study's authors caution that receiving genetic feedback is just the first step in behavior change, and connecting individuals to resources and support is crucial.
SourceRutgers University·JournalAmerican Journal of Medical Genetics·TypeExperimental study·DateMay 30, 2023
A recent study published in Calcified Tissue International found that heavy drinkers are at risk of muscle loss and frailty. The research, which analyzed data from the UK Biobank, suggests that consuming 10 units or more of alcohol per day can lead to lower muscle mass, even when adjusted for body size and other factors.
SourceUniversity of East Anglia·JournalCalcified Tissue International·TypeObservational study·DateMay 24, 2023