Researchers found that people with prolonged COVID-19 symptoms experienced reduced performance in mental tasks up to two years post-infection. Those who didn't feel fully recovered after infection showed lower task accuracy scores.
The National Institute of Allergy and Infectious Diseases has awarded five projects to better understand Post-treatment Lyme Disease Syndrome (PTLDS), which affects 10-20% of Lyme disease patients. The research will explore possible causes of persistent symptoms, including a misguided immune response and ongoing infection.
The IU team has made significant contributions to the Human BioMolecular Atlas Program, including the development of Organ Mapping Antibody Panels and the creation of a Human Reference Atlas. The research papers cover various aspects of tissue mapping, organ imaging, and data visualization.
Researchers have created a biomedical compound that can block the interaction of metastasis-inducing protein S100A4 with its target inside the cell. The compound inhibits properties associated with metastasis at very low doses, showing potential therapeutic role in breast cancer treatment.
Dr. Eric Lazartigues has been recognized for his groundbreaking research on salt-sensitive hypertension and the role of the brain renin-angiotensin system in regulating blood pressure. His work has led to a deeper understanding of hypertension's impact on cardiovascular diseases and mortality.
A new $7 million grant will support research into the mechanisms that exacerbate inflammatory disease. The study aims to understand how environmental chemicals affect the gut microbiome, a key factor in chronic diseases like obesity and type 2 diabetes.
The 'warm Arctic–cold Eurasia' pattern influences winter sea-ice anomalies in the Barents–Kara Sea, with a subseasonal transition from negative to positive ice coverage. This phenomenon is linked to atmospheric and oceanic changes driven by global warming.
KERI develops the core source technology to increase motor capacity to IE4 level, reducing energy loss by 20% and cost, securing market competitiveness for domestic SMEs. The 'open platform' enables companies to utilize related technologies and improve efficiency.
A study published in The Lancet Healthy Longevity found that metformin may promote healthy ageing by reducing biomarkers of ageing and increasing telomere length. The research team used genetic analysis to identify variants associated with metformin use, suggesting a potential role for the drug in promoting healthy longevity.
Researchers investigate how water molecules react with or on nanoparticle surfaces in aqueous solutions. They found that acidic conditions cause water molecules to split on hematite nanoparticles, while basic pH is required for anatase nanoparticles.
Researchers at MIT have developed a novel sensor that can detect immune molecule CXCL12, which plays a crucial role in several human diseases including cancer. The device uses receptor proteins found in cell membranes, making it a potential tool for early screening of hard-to-diagnose cancers.
A study found that ancient kurgans in the Eurasian steppes can preserve steppe grasslands and biodiversity due to their cultural significance. The presence of spiritual and cultural values on these sites increases the chance of grassland presence, comparable to protected areas.
Brigham researchers use induced pluripotent stem cells to restore hormone production and fertility in mice with premature ovarian failure. The study shows promise for treating incurable conditions and may lead to new therapies for patients with ovarian failure.
Researchers recruited tourists to collect sediment samples on remote Arctic beaches, finding a higher-than-expected level of microplastic pollution. The study identified two specific sources of plastic pollution: polypropylene fibers from fishing nets and polyester-epoxide particles from ship color coatings.
Using Germanene, researchers have developed two new methods for generating ultrafast mode-locking operations in fiber lasers. These methods utilize the material's fast carrier relaxation time and large nonlinear absorption coefficient to produce femtosecond pulses and higher energy noise-like pulses.
Researchers developed modular optical sensors capable of detecting viruses and bacteria using fluorescent carbon nanotubes with DNA anchors. The sensors showed high reliability and selectivity in detecting SARS-CoV-2 protein, offering advantages for complex environments and future diagnostic applications.
Despite high ratings, child car seat installation errors are common, with most frequent errors found in seat belt installations and top tether usage. Certified technicians can provide guidance on correct installation and usage, ensuring optimal safety for young passengers.
Researchers at Penn State have received a $2 million NIH grant to develop high-throughput spheroid (HTS) bioprinting technology, which can quickly fabricate scalable, native tissues. The technology has the potential to repair bone in sensitive places like the skull and could be used for implantation, research, or disease modeling.
A new study from Northwestern University found that only 13% of US parents and caregivers are aware of the 2017 NIH guidelines recommending early peanut introduction to prevent peanut allergy. Despite this, more work is needed to educate families and clinicians about the guidelines.
The STREAM project developed the StreamEXO exoskeleton, which reduces musculoskeletal system's ergonomic risk of physical overload by 50% and muscle fatigue by 30%. The device generates forces to support workers' backs during heavy manual material handling activities.
A muscle-building supplement called beta-hydroxy beta-methylbutyrate (HMB) has been shown to reduce plaques and increase factors for neuronal growth in mice with Alzheimer's-like pathology. The study found that HMB stimulates a nuclear hormone receptor to improve memory and learning in mice with Alzheimer's disease.
Extracellular vesicles from fibrotic lungs can activate dormant fibroblasts in healthy lungs, initiating fibrosis development and spreading. The study's findings support the potential use of EVs as a targeted drug therapy platform to slow fibrosis progression and improve patient outcomes.
Telehealth use in Michigan has increased significantly, especially for mental health needs and rural residents. The study found that 11-17% of appointments take place virtually, up from less than 1% before the pandemic.
A new position paper reviews TBS for fracture risk prediction, treatment initiation and monitoring in osteoporosis. The evidence-based guide provides practical guidance for clinicians to integrate TBS into clinical practice.
A study published in Neuron reveals that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neurone Disease, a condition that causes paralysis. The researchers found that mislocalisation affects many more proteins than first thought, especially those involved in RNA binding.
A new 'fly-to-bedside' resource has been developed to sort through the complexities of SARS-CoV-2 virus-host interactions. Researchers found that nine out of 10 non-structural proteins resulted in wing defects, providing a basis for understanding how viral proteins affect host proteins.
Researchers developed a tailored approach to weight loss and cardiometabolic risk factors, showing significant improvement in targeted areas like abnormal fullness and emotional eating. The study suggests the need for an actionable, phenotype-based classification of patients in obesity treatment, moving beyond reliance on scales or bod...
Researchers at Salk Institute discovered molecular mechanisms of HIV drug-resistance to Dolutegravir, a breakthrough that could lead to the development of new HIV therapeutics. The study revealed how changes in integrase protein structure can lead to resistance and how another compound, 4d, may overcome this resistance.
Researchers discovered that long non-coding RNAs are essential for the survival of the parasitic worm causing schistosomiasis. Silencing these RNAs prevents reproduction and egg release, leading to parasite death. This finding offers a promising new approach to treating this neglected disease.
Researchers at the University of Copenhagen have discovered a way to replace diseased and aged brain cells with new ones, which could lead to treatments for neurodegenerative diseases like Huntington's disease and multiple sclerosis. The study used humanized mice models to test the effectiveness of glial cell transplantation.
Researchers found that organic matter can regulate groundwater arsenic mobilization and release, highlighting the need for comprehensive strategies to mitigate environmental risks. The study's findings have important implications for managing and mitigating groundwater pollution caused by the infiltration of organic matter.
This study shows that shared medical appointments significantly improved patient satisfaction, learning, and medication compliance for patients with primary glaucoma. The research demonstrated no compromise in follow-up rates or measured clinical outcomes.
A better way to wirelessly charge over long distances has been developed, utilizing the phenomenon of radiation suppression. The research shows high transfer efficiency, over 80 percent, can be achieved at distances approximately five times the size of the antenna.
The study found two distinct groups: low maternal sleep (5-6 hours/night) and average maternal sleep (7-8 hours/night). Children in the low maternal sleep group slept less. Establishing early bedtime routines and consistent sleep patterns improved sleep duration and reduced sleep problems.
A study from Konstanz and Baltimore reveals that around 4.2 million animals have been used for hazard assessment under REACH, with many more expected due to a 2022 revision. Animal-free alternative methods are advocated by researchers, who argue that they provide more meaningful results than animal testing.
Researchers identified structural chokepoints in US agri-food supply chains to enhance resilience and security, critical for global food systems. The study's findings may inform policies aimed at bolstering the nation's ability to respond to threats.
A recent study has found that babies born to fathers with psychiatric diagnoses are more likely to be born prematurely. The study analyzed data from over 1.5 million births in Sweden and found a significant increase in preterm births among infants whose father had a psychiatric diagnosis.
A team of researchers at the University of Notre Dame analyzed nearly 600 colonial notes to understand Franklin's innovative techniques for making paper money. They found distinctive security features, including pigments and materials like muscovite that made his bills harder to counterfeit.
Researchers have found a key role for NFIC in acinar cell maturation and limiting tumour formation in the pancreas. The molecule helps acinar cells work properly, reducing the risk of pancreatic cancer.
Researchers used fiber optic distributed acoustic sensing to track induced seismicity from a CO2 injection in Victoria, Australia. The study found that tiny earthquakes accompanied the saturation front of the CO2 plume, rather than the pressure front.
Scientists trapped ordinary photons in superconducting radio frequency cavities to search for dark photon transitions, demonstrating unprecedented sensitivity and the world's best constraint on dark photon existence. The experiment used SRF cavities with high efficiency and covered new parameter regions for dark photon mass.
Research suggests that larger cosmic dust aggregates are less likely to stick together after collisions. This limits the growth of planetary building blocks, complicating the process of planet formation. Simulations reveal that size is a critical factor in determining sticking probability, with larger aggregates more prone to bouncing.
A combination of Lactobacillus acidophilus and Lacticaseibacillus rhamnosus strains successfully inhibited the production of superantigens causing toxic shock syndrome. Probiotics may also prevent growth of Staphylococcus aureus, a virulent strain that produces proteins triggering the disease.
Researchers have demonstrated a method to power water remediation using renewable energy sources, including solar power. Through electrochemical separation and redox reactions, they successfully removed arsenate from wastewater.
In a study published in Animal Behaviour, researchers found that male field crickets adjust their song patterns based on the proximity of rivals. When another cricket is within one meter, males are less likely to sing, suggesting they prioritize territorial defense over courtship displays.
Researchers developed a strategy to predict chemotherapy response in triple negative breast cancer (TNBC) using the Kinase Inhibitor Pulldown Assay (KIPA). The study identified a seven-purine-binding protein signature that predicted chemotherapy sensitivity and favorable clinical outcomes.
A research team from Hokkaido University has found an exceptionally preserved fossil forest of Wataria parvipora, which was predominantly accompanied by Byttneriophyllum leaves. The discovery helps reconstruct a whole Eurasian plant from the late Miocene epoch and sheds light on the taxonomic identity of plants.
A recent study reveals a massive section of the Andes experiencing significant greening, defying climate zone expectations. The researchers found that this area, stretching from northern Peru to northern Chile, has seen its vegetation growing significantly over the past 20 years.
Dr. Beau Webber received a two-year Translation to CURE award to study genetically engineered gamma delta T cells for treating metastatic osteosarcoma. This innovative approach aims to address the limitations of current immune-cell based therapies and offers new hope for childhood cancer treatment.
A new study found that gastric bypass surgery is associated with a higher incidence of non-alcohol substance use disorder, particularly other psychoactive substance-related disorders. The study suggests healthcare professionals should consider this risk when caring for patients treated with gastric bypass surgery.
A study finds that additional recommended cervical cancer screenings before birth are associated with an increased risk of preterm delivery. The findings suggest that cervical cancer screening guidelines should consider the downstream implications for preterm delivery risk when weighing population-level costs against benefits.
Researchers at Rice University have discovered a metal oxide that can enable terahertz technology for quantum sensing. The material, strontium titanate, exhibits unique properties that allow it to interact strongly with terahertz light, forming new particles called phonon-polaritons.
Research finds that skin keratinocytes regulate temperature sensation by controlling the amount of TRPV3 proteins, reducing their activity when bound to TMEM79. This discovery resolves controversy over skin keratinocytes' involvement in temperature detection.
Researchers from Korea University Medicine have discovered a potential therapeutic target for overcoming cisplatin resistance and neuropathic pain in cervical cancer. By inhibiting TRPV1, they found that resistant tumors became vulnerable to cisplatin, improving the outlook for patients.
The latest issue of SLAS Discovery features novel technologies and approaches to develop and characterize chemical and biological tools for human disease treatment. The journal reports on high-throughput screening-related research, including fluorescence polarization assay use and glycomimetics.
A study at University of Tsukuba found that pharmacists with higher assertiveness scores are more likely to initiate communication that leads to physicians altering prescriptions. This suggests that effective communication skills can improve the safety of drug therapy.
Researchers found evidence of a precursory phase of fault slip occurring two hours before large earthquakes, using global GPS time-series data from nearly 100 major quakes worldwide. The study suggests that many large earthquakes start with a precursory phase of slip or represent the tail end of a longer process.
A Swiss patient has achieved 20 months of HIV remission after a bone marrow transplant performed as part of cancer treatment. The patient's cells remained HIV-permissive despite the absence of a protective mutation, yet the virus was still undetectable after antiretroviral therapy was discontinued.
A new study from UC Davis Health found that volunteering in late life is associated with better executive function and episodic memory. Those who volunteered several times per week had the highest levels of executive function, potentially serving as a simple intervention against Alzheimer's disease and associated dementias.
A new study finds that only a small number of US policies consider ultra-processed foods, which have been linked to weight gain, diabetes, and certain cancers. The US lacks national dietary guidelines for these foods, despite international countries like Belgium, Brazil, and Israel having incorporated them.