Thomas Jefferson University researchers have created a human immune system mouse model that closely mimics the response to a tick-borne infection in humans. The study found that mice developed B1b-like cells, specialized antibody-producing systems used to fight bacterial pathogens, which helped resolve the infection.
SourceThomas Jefferson University·JournalProceedings of the National Academy of Sciences·DateDec 14, 2011
Scientists have solved the structure of a key region in Ler, a protein linked to E.coli virulence. This breakthrough could lead to alternative treatments and minimize antibiotic resistance.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalPLOS Pathogens·DateDec 9, 2011
Tel Aviv University engineers have developed an efficient liquid solution that can alter the genetic make-up of antibiotic-resistant bacteria, making them sensitive again. The solution is easy to prepare and apply, and non-toxic, with potential to be added to antibacterial cleansers.
SourceAmerican Friends of Tel Aviv University·JournalApplied and Environmental Microbiology·DateDec 9, 2011
Salmonella forms two genetically identical types, each with an advantage in infection and evasion. The bacteria's ability to produce flagellin triggers a self-destructive response in immune cells, but restricting production helps it colonize hosts.
SourceUniversity of Washington·JournalProceedings of the National Academy of Sciences·DateDec 8, 2011
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A comprehensive study of premature infants found that they harbor fewer diverse microbes than full-term infants, with harder-to-treat Candida fungus and harmful bacteria prevalent. The research highlights the importance of balance in the infant's gut microbiome and suggests that probiotic substances may be beneficial.
SourceDuke University Medical Center·JournalPLOS ONE·DateDec 8, 2011
Researchers at the University of Gothenburg have discovered a brand new tick-borne infection, Neoehrlichia mikurensis, which causes Deep Vein Thrombosis (DVT) in people with impaired immune systems. The infection has been reported in eight cases worldwide, three in the Gothenburg area.
SourceUniversity of Gothenburg·JournalJournal of Clinical Microbiology·DateDec 6, 2011
A new study published in the Canadian Medical Association Journal found that hospital-acquired C. difficile infection increases length of stay in hospital by an average of six days.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateDec 5, 2011
Researchers found that bacteria wait until the last minute to synthesize glue for permanent attachment, using flagella and pili to facilitate timely release. This mechanism may help design drugs to prevent infections by targeting adhesin stimulation.
SourceIndiana University·JournalMolecular Microbiology·DateNov 30, 2011
Researchers at Duke University Medical Center found that surgery significantly improves short- and long-term outcomes in patients with heart failure caused by bacterial endocarditis. The study showed patients who underwent surgery had a lower mortality rate compared to those treated with medical therapy alone.
SourceDuke University Medical Center·JournalJAMA·DateNov 22, 2011
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Preemies with AB blood type are nearly three times as likely to die from necrotizing enterocolitis (NEC) as those with other blood types. Changing blood transfusion practices could significantly reduce NEC incidence by providing specific blood types.
SourceLoyola Medicine·JournalJournal of Perinatology·DateNov 21, 2011
A novel antibacterial protein, Avidocin, demonstrates potential for preventing and treating E. coli O157:H7-induced diarrhea and intestinal inflammation in an animal study. The protein also carries fewer bacteria in the feces of infected animals, making it a promising alternative to conventional antibiotics.
SourceKureczka/Martin Associates·JournalAntimicrobial Agents and Chemotherapy·DateNov 21, 2011
Researchers have discovered a defect in the cell-targeting ability of Helicobacter pylori bacteria that leads to reduced inflammation in the stomach. The study found that the bacteria's chemotaxis, or movement towards specific chemicals, plays a crucial role in triggering chronic inflammation.
SourceUniversity of California - Santa Cruz·JournalProceedings of the National Academy of Sciences·DateNov 21, 2011
Bacteria become resistant to antibiotics when starved due to the ability of outer layer cells to sense nutrients, producing a protective mechanism against toxic oxygen radicals. Disrupting this function could improve treatment for infections.
SourceUniversity of Washington·JournalScience·DateNov 17, 2011
Researchers discovered a transporter system in bacteria that protects itself from immune attack by transporting molecules meant to destroy it away from its inner membrane target. This mechanism helps bacteria survive in the host, but also presents an opportunity for developing novel antibiotics.
SourceNationwide Children's Hospital·JournalPLOS Pathogens·DateNov 17, 2011
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Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers identified a process by which Legionella bacteria trick host cells into generating amino acids, necessary for growth and infection. The study's findings could lead to the development of new antibiotics and vaccines.
SourceUniversity of Louisville·JournalScience·DateNov 17, 2011
The world is facing a dire shortage of new antibiotics, with increasing resistance making treatment increasingly difficult. Professor Laura Piddock calls for urgent action to turn this around, citing the need for increased public awareness and government support.
SourceThe Lancet_DELETED·JournalThe Lancet Infectious Diseases·DateNov 17, 2011
Researchers developed a novel compound that blocks bacterial adhesion to bladder walls, alleviating weeks-long infections in mice. The treatment has the potential to treat antibiotic-resistant UTIs and may be effective against other types of infections.
SourceWashU Medicine·JournalScience Translational Medicine·DateNov 16, 2011
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Paul Kubes, a University of Calgary researcher, has won the 2011 Canada's Health Researcher of the Year award for his groundbreaking work on visualizing the mammalian immune system. His research focuses on understanding sepsis and its relationship to other diseases such as stroke, cancer, and diabetes.
Researchers at Wayne State University will study a novel antibiotic, daptomycin, to treat vancomycin-resistant Enterococcus (VRE) infections and decrease mortality. The goal is to determine the optimal doses of daptomycin to achieve greater bactericidal activity and prevent resistance.
SourceWayne State University - Office of the Vice President for Research·DateNov 16, 2011
The study found that pneumonia is the most common serious infection after heart surgery, occurring in 2.4 percent of patients, followed by C. difficile colitis and bloodstream infections. Risk factors for infection include congestive heart failure, hypertension, and length of stay.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers discovered Mycobacterium tuberculosis produces a protein that disables the immune response, allowing the bacteria to live comfortably in human cells. This breakthrough provides new targets for developing better treatments against this devastating disease.
SourceUniversity of British Columbia·JournalProceedings of the National Academy of Sciences·DateNov 14, 2011
Researchers sequenced bacterial genomes to understand how a pathogen evolves in response to human defenses and medical treatment. The study found widespread purifying selection, but also identified specific genes that showed strong evidence of positive selection.
SourceHarvard Medical School·JournalNature Genetics·DateNov 13, 2011
The study reveals that while the Hib vaccine has reduced Hib disease in young children, other strains of the bacteria continue to cause substantial disease in older adults and infants. The burden of disease is highest among the elderly and youngest age groups, with nearly a quarter of cases being fatal.
SourceInfectious Diseases Society of America·JournalClinical Infectious Diseases·DateNov 11, 2011
An international team of scientists discovered how a bacterial pathogen kills cells by preventing protein synthesis, paving the way for novel therapies to combat melioidosis. The study, led by the University of Sheffield, used intense X-rays to solve the structure of a protein from Burkholderia pseudomallei.
SourceUniversity of Sheffield·JournalScience·DateNov 10, 2011
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
The university will conduct research on deciphering and controlling the signaling processes in bacterial multicellular systems and bacteria-host interactions. This study aims to understand persister formation in biofilm development and manipulate the multicellular and inter-kingdom signaling processes.
A study found that environmental growth of Acinetobacter baumannii was detected in 48% of patient rooms, with surfaces like supply cart handles and floors being most commonly contaminated. Patients with recent or remote MDR-AB colonization or infection showed similar levels of environmental contamination.
SourceElsevier Health Sciences·JournalAmerican Journal of Infection Control·DateNov 1, 2011
Four Michigan State University researchers are working on new projects to combat cystic fibrosis, using funds from the $110,000 grant from Hunt for a Cure. The studies aim to develop new treatments and prevent bacterial infections, with a focus on understanding the role of molecules, genes, and biofilms in the disease.
A study published in Proceedings of the National Academy of Sciences reveals how Helicobacter pylori bacteria disrupts mitochondrial function to induce cell death. The researchers found that the bacterial toxin VacA recruits a host protein to activate apoptosis, a process linked to cancer development.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·DateNov 1, 2011
Fecal microbiota transplants have shown high efficacy in treating recurrent C. difficile infections, with a success rate of 91% in one study. The procedure has also been effective in treating Inflammatory Bowel Disease, particularly when done recurrently. Researchers found that fecal transplant is a safe and effective treatment option ...
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers found that antibiotics are not the sole risk factor for community-acquired Clostridium difficile infection and that nursing home residence is a strong predictor of disease severity. The study identified increasing age, higher Charlson Comorbidity index, and lack of antibiotic exposure as predictors of hospitalization.
SourceAmerican College of Gastroenterology·JournalThe American Journal of Gastroenterology·DateOct 31, 2011
Researchers discovered a key enzyme, IreK, involved in resistance to cephalosporins, while another enzyme, IreP, regulates its activity. This understanding could lead to new strategies for controlling enterococcal infections and developing new treatments.
SourceAmerican Society for Microbiology·JournalmBio·DateOct 31, 2011
A new study by researchers at Worcester Polytechnic Institute shows that cranberry juice is more effective than proanthocyanidin extracts in preventing biofilm formation, a precursor to urinary tract infections. The study found that cranberry juice completely prevented biofilm formation, while extracts showed limited ability to reduce it.
SourceWorcester Polytechnic Institute·JournalFood Science and Biotechnology·DateOct 28, 2011
A new study by Duke neuroscientists identifies the source of learning difficulties as an overactive immune response, triggered by early-life infections. The researchers found that specialized immune system cells in the brain called microglia release a signaling molecule called Interleukin-1, which can impair learning and memory.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers found that certain strains of Staphylococcus aureus bacteria have genetic variants that enable them to form biofilms on cardiac devices. This discovery offers clues for preventing infections in patients with implanted devices, which currently cost thousands of dollars and millions of dollars in healthcare costs each year.
SourceU.S. National Science Foundation·JournalProceedings of the National Academy of Sciences·DateOct 25, 2011
Scientists have identified a specific genetic variation in Staph bacteria that increases its ability to form bonds with fibronectin, leading to infections in implanted cardiac devices. This discovery has implications for preventing biofilm-related infections and could lead to new protocols for assessing risk.
SourceDuke University Medical Center·JournalProceedings of the National Academy of Sciences·DateOct 24, 2011
Researchers found that specific genetic variants in Staph surface proteins create stronger bonds with human blood proteins, leading to infection. The study aims to develop techniques to prevent these infections by understanding the initial step of biofilm formation.
SourceOhio State University·JournalProceedings of the National Academy of Sciences·DateOct 24, 2011
A recent study has demonstrated the effectiveness of antimicrobial copper surfaces in reducing hospital-acquired infections. By replacing traditional objects with antimicrobial copper versions, the study found a significant decrease in bacterial growth and infection rates.
Researchers at UT Southwestern Medical Center have made significant breakthroughs in understanding the dynamic intestinal ecosystem, suggesting new approaches to prevent inflammatory bowel disease (IBD) and viral infections. They found that certain bacteria can increase polio virus infectivity by activating it.
SourceUT Southwestern Medical Center·JournalScience·DateOct 19, 2011
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
The Trudeau Institute has made a breakthrough in treating Listeria infections by identifying a key role for blood-clotting proteins in immune defense. The study suggests that FXI-targeted therapeutics may be useful for treating severe infections caused by Listeria and other sepsis-causing bacteria.
SourceTrudeau Institute·JournalInfection and Immunity·DateOct 17, 2011
The Peggy Lillis Memorial Foundation honors Dr. Sherwood Gorbach for his pioneering research and efforts to combat Clostridium difficile infection, a bacterial infection causing severe diarrhea and inflammation of the colon. The award recognizes his contributions to increasing prevention and minimizing death and disability from C. diff.
A global team of scientists has identified a natural mutation in Clostridium difficile that causes the bacterium to produce hypervirulent strains resistant to antibiotics, leading to severe bowel infections.
Researchers have identified a toxin called SElX released by MRSA that triggers an extreme immune response. By targeting this toxin, it may be possible to prevent severe infections and high fever associated with MRSA.
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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Scientists analyzed polymorphisms in the MIF gene to identify its role against bacterial infections. The study found specific variants that protect against meningitis and increase mortality.
SourceFederation of American Societies for Experimental Biology·JournalThe FASEB Journal·DateOct 12, 2011
Researchers discovered that vitamin D is essential for triggering an effective immune response against tuberculosis, a potentially fatal lung disease. They found that T-cells release a protein called interferon-γ that requires sufficient levels of vitamin D to activate immune cells and kill the bacteria.
SourceUniversity of California - Los Angeles Health Sciences·JournalScience Translational Medicine·DateOct 12, 2011
Researchers identified a novel mechanism where Chlamydia trachomatis tricks host cells into taking up the bacteria by coating itself with a growth factor made by the cells. This disguise creates a positive feedback loop, enabling bacterial infection and spread.
The TB bacterium has a unique molecule on its outer surface that blocks the production of tumor necrosis factor (TNF), a key protein in the body's immune response. This allows the bacterium to remain infectious and evade the host's defense.
SourceOhio State University·JournalProceedings of the National Academy of Sciences·DateOct 3, 2011
A study found that residential washing machines often can't kill dangerous hospital-acquired bacteria at lower water temperatures. Washing with hot water and ironing afterwards can eliminate MRSA and Acinetobacter from uniforms.
SourceSociety for Healthcare Epidemiology of America·JournalInfection Control and Hospital Epidemiology·DateOct 3, 2011
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers identified a novel mechanism by which Burkholderia pseudomallei develops resistance to ceftazidime, making it difficult to detect. The study found that genetic mutations lead to the production of a protein important for bacterial cell division, rendering the drug ineffective.
SourceWellcome Trust·JournalProceedings of the National Academy of Sciences·DateOct 3, 2011
Paul Kenis and James Slauch have been recognized as University Scholars for their exceptional contributions to the field of chemical engineering and microbiology. Their research focuses on developing novel microfluidic tools and studying Salmonella bacteria to understand its virulence and develop new treatments.
SourceCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign·DateSep 20, 2011
Researchers at Arizona State University are developing strategies to diagnose and prevent two of the most pervasive food-borne microbes, focusing on extraintestinal pathogenic E. coli (ExPEC) and noroviruses. The new initiatives aim to improve food safety and reduce human illnesses, particularly among vulnerable populations.
Jennifer Juarez, a UTHealth doctoral student, has been awarded two research fellowships to study the spread of E. coli, a hard-to-treat bacterium that can lead to food poisoning and fatal disease. Her research focuses on understanding how bacterial cells divide and proliferate, paving the way for novel antibacterial treatments.
SourceUniversity of Texas Health Science Center at Houston·DateSep 20, 2011
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A study published in mBio reveals that the 2009 H1N1 pandemic flu virus causes more extensive damage to lung tissues than seasonal flu, making it more susceptible to bacterial infections like pneumonia. This damage compromises the protective epithelial cells, allowing bacteria to thrive and increase mortality.
SourceAmerican Society for Microbiology·JournalmBio·DateSep 19, 2011
A new compound has been developed to treat C diff infections, showing promise in killing and preventing the bacterium. The compound, MGB BP-3, is more effective than vancomycin in treating C diff and offers a potential solution for life-threatening infections.
Researchers at the University of Sheffield have created a new technology that detects bacterial infections in wounds using ultra-violet light. The polymers, attached to antibiotics, bind to bacteria and fluoresce, alerting clinicians to the severity of infection and guiding antibiotic treatment.
SourceUniversity of Sheffield·JournalBiomacromolecules·DateSep 15, 2011
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers are working with major UK retailers to reduce bacterial infections in chickens and lower food poisoning cases. The study focuses on improving chicken welfare to combat Campylobacter infection, a leading cause of food poisoning.
Jörn Coers is honored by the American Society for Microbiology for his work on immune responses against intracellular pathogens. His research focuses on host-pathogen interactions and has revealed key insights into diseases caused by Chlamydia.
Benjamin P. Howden, a leading expert in S. aureus and E. faecium research, receives the award for his groundbreaking work on antimicrobial resistance mechanisms and virulence. His research has led to new insights into vancomycin-intermediate S. aureus and reduced linezolid susceptibility.
A team of researchers from University of Houston and St. Luke's Episcopal Hospital are working to develop improved screening methods for detecting drug-resistant superbugs, specifically carbapenem-resistant Klebsiella pneumoniae (CRKP). The bacteria can cause deadly infections in people with weakened immune systems.
SourceUniversity of Houston·JournalDiagnostic Microbiology and Infectious Disease·DateSep 8, 2011
Researchers analyzed the genome of a superbug called vancomycin-resistant enterococci (VRE) to understand its resistance to antibiotics. They identified changes in genes that led to daptomycin resistance, offering insights into developing new drugs to combat this growing health threat.
SourceUniversity of Texas Health Science Center at Houston·JournalNew England Journal of Medicine·DateSep 8, 2011
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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers found that children with malaria are more susceptible to bacteraemia due to the infection itself, not a natural protection from the sickle cell gene. Malaria prevention strategies may also reduce invasive bacterial infections, with an estimated 50% of cases in endemic areas attributed to Plasmodium falciparum.