Articles tagged with Brain Cancer
The Seneca Valley Virus shows promise as a treatment for some metastatic cancers. Cervical cancer survivors are at greater risk of second cancers due to radiation exposure. A novel trial design identifies promising treatments in clinical trials.
UT Southwestern researchers Dr. Luis Parada and Dr. Thomas Südhof have been elected to the Institute of Medicine for their international distinction in developmental biology and neuroscience. They join a prestigious group of medical scientists shaping public health policies and advising federal governments.
A new report found that children with brain tumors have lower grades in each subject, particularly in foreign language, with over 58% of female patients receiving below an eight. Despite this, most survivors completed the ninth grade at the usual age, suggesting a glimmer of hope for these students.
A review of published literature found that delays in childhood cancer diagnosis are short but the impact on prognosis remains unclear. The study suggests that delays can be attributed to gatekeeper-type healthcare systems, clinical presentation, stage of disease, and parent/patient factors.
Researchers at M. D. Anderson Cancer Center have identified a new oncogene, insulin-like growth factor binding protein 2 (IGFBP2), that contributes to the formation of two types of brain malignancies, astrocytoma and oligodendroglioma.
A large study of 28,000 Danish utility workers found no evidence of increased cancer risk from low-frequency electromagnetic fields. However, women exposed to medium frequency fields were more likely to develop brain cancer than those with lower exposure levels.
Boston College biologists identify KetoCal as an effective alternative therapy for malignant brain cancer, slowing tumor growth and enhancing health in mice. The study found that KetoCal decreased tumor growth by 35-65% and improved survival rates compared to standard diets.
Researchers found that dual therapy with Avastin and chemotherapy agent irinotecan halted tumor growth up to twice as long as comparative therapies, offering a significant advance in treatment for aggressive gliomas. The study's findings may lead to new options for patients with the poorest possible prognosis.
A new study found that the loss of PTEN function in glioma cells leads to high levels of B7-H1 expression, making it harder for T-cells to kill cancer cells. This discovery may have implications beyond brain tumors and could affect the effectiveness of emerging therapies.
A large cohort study of over 420,000 cell phone users found no link between long-term or short-term cell phone use and an increased risk of brain tumors, salivary gland tumors, eye tumors, or leukemias. The study suggests that cell phone use is not associated with cancer risk.
Researchers are evaluating the use of Aricept to prevent cognitive decline and memory problems in pediatric brain cancer survivors who have received cranial radiation. The study, which will enroll 35 patients ages 8-17, aims to assess whether the drug can help maintain baseline cognitive abilities and social relationships.
Research from the University of Minnesota found that children who received radiation for cancer are at higher risk for developing secondary brain tumors. Prolonged follow-up is crucial for early detection, and long-term screening recommendations are needed for all childhood cancer survivors.
Researchers have found that a cancer-fighting virus called VSV kills the most malignant form of brain cancer in mice, targeting invasive tumour cells. The study also discovered that delivering VSV intravenously can effectively treat malignant glioma with minimal side effects.
Childhood cancer survivors are at higher risk for developing second cancers, including CNS tumors, which can have devastating consequences. Radiation exposure is associated with a higher risk of malignant brain tumors like glioma and benign tumors like meningiomas, particularly in children under age 5.
A recent study by the University of Rochester Medical Center found that lead exposure is associated with an increased risk of brain cancer in adults. The research, which analyzed data from over 318,000 people, revealed a 50% higher death rate among those exposed to lead compared to unexposed individuals.
A six-month walking exercise program may help alleviate cognitive impairment in cancer survivors. Researchers aim to identify new tactics to improve quality of life for those affected by chemotherapy-induced memory problems.
Researchers found space-time clustering of glioma tumour cases in different geographical locations, consistent with patterns caused by infections. The study suggests a possible link between infection and brain tumours, potentially leading to future preventative measures.
A study analyzing cancer cases in young children over 45 years found space-time clustering of leukaemia and brain tumour cases, suggesting a potential link between infectious viruses and childhood cancer. The research suggests that minor illnesses during early childhood may trigger cancer in genetically susceptible individuals.
Researchers introduce molecularly engineered DNA strands into cell cultures to detect biomarkers in complex samples. The technique could help identify cancers at earlier stages and monitor residual cancer after treatment.
A University of Minnesota study reveals that nearly 20% of childhood cancer survivors experience physical limitations and trouble performing daily activities. Survivors of brain and bone cancers are most affected, with many reporting difficulties attending work or school.
A study of 11,481 childhood cancer survivors found that 20% had physical performance limitations compared to 12% of their siblings. Rehabilitation programs improved survival rates after heart attacks by reducing subsequent heart attacks by 17%.
Researchers developed a new radiation technique that targets cancer while sparing hair follicles, resulting in minimal hair loss. The study used intensity modulated radiation therapy (IMRT) on 10 patients with stage IV brain cancer, showing promising results and improved overall survival rates.
A team of researchers from the University of Illinois at Urbana-Champaign has developed an alternative therapy to surgery for brain cancers. By engineering T-cell receptors with enhanced binding capacity, the approach aims to eradicate tumors with minimal side effects.
Childhood cancer survivors are more likely to experience academic problems, social isolation, and difficulties with friendships. Researchers found that these issues affect up to 46% of survivors, particularly those with brain cancers, leukemia, or neuroblastoma.
Neural stem cells in the subventricular zone of the forebrain give rise to malignant astrocytoma in genetically engineered mice. The study challenges current dogma that tumors arise from glial cells throughout the brain.
A recent study suggests that Gulf War veterans may be at a greater risk of developing brain cancer, potentially linked to exposure to nerve agents during the conflict. The National Academies of Sciences, Engineering, and Medicine report highlights the need for further research into this potential health consequence.
Tom Curran, a prominent cancer researcher, has been elected Fellow of the Royal Society. His work on molecular oncology and neurobiology has made significant impacts on our understanding of brain cancers and gene regulation.
Scientists at Johns Hopkins Medicine have identified Notch2 as a key gene target in childhood brain tumors, medulloblastoma. High levels of the Notch2 gene are associated with poorer outcomes and cancer cell growth promotion.
A new RNAi delivery system has been developed to target brain cancer cells, using antibodies to cross the blood-brain barrier. The treatment has shown promising results in mice with brain tumors, increasing survival time by almost twice as much as a control group.
A recent study by the American Academy of Neurology found that people with low incomes are at a higher risk of developing brain tumors. The study analyzed data from Michigan and found a significant difference in brain cancer rates between those with low incomes and those without, particularly among younger adults.
A study of 32 patients with suspected paraneoplastic neurological disorders found that PET imaging successfully identified relevant lesions undetectable by alternative methods. The results suggest that PET is an appropriate and promising tool for patients with undiagnosed paraneoplastic neurological disorders.
Researchers used microarray technology to compare gene expression in healthy flies and those with brain cancer, finding significant changes in 321 genes involved in metabolism, cell proliferation, and more. The study identified a key tumor-suppressor gene mutation that causes cancerous tissue growth and metastasis in flies.
Researchers at Cedars-Sinai Medical Center are studying the link between brain cancer and air pollution, led by Dr. Keith Black. The study aims to determine whether exposure to toxic air pollutants can cause changes in brain tissue associated with brain cancer formation.
A new combination cancer-killing drug regimen has shown promising results in extending patient survival, with 16% tumor shrinkage and 35% stable disease progression after six months. The orally administered treatment has been well-tolerated and offers a more convenient option for patients compared to traditional IV chemotherapy.
St. Jude researchers successfully cloned embryos from mouse medulloblastoma cells using a reprogrammed nucleus model, demonstrating the potential for epigenetic factors to cause tumors. The study provides valuable insights into the molecular basis of cancer and may lead to new therapies.
Scientists have discovered a new hedgehog blocker that stops medulloblastoma tumor growth and kills cancer cells in mice and human patients. The study provides hope for the development of new treatments for this deadly childhood brain cancer.
Researchers used gene modification to deliver Interleukin 12 directly into glioma, a deadly type of brain cancer resistant to treatment. The study showed significant prolonged survival in mice and improved immune system's ability to infiltrate and kill tumor cells.
Researchers found that death rates from brain cancer were close to expected levels for the general population, with no increased risk of lifetime or recent exposure. Socioeconomic factors played a role in increasing premature death risk, but not brain cancer risk.
A large case-control study found no association between cell phone usage and the development of primary brain cancer in a cohort of 891 participants. The study, published in JAMA, analyzed data from patients with primary brain cancer and controls without cancer, finding no correlation between cell phone use and brain cancer risk.
A recent study published in The Journal of the American Medical Association has found that handheld cellular telephone use is not associated with an increased risk of brain cancer. Researchers conducted a case-control study from 1994 to 1998 and analyzed data on 469 participants with primary brain cancer and 422 matched controls.
A study of childhood brain tumors found that children born in late summer or fall were more likely to develop medulloblastoma than the general population. Researchers also discovered a link between longer symptom duration for boys and lower stage of disease at diagnosis, potentially affecting diagnoses and treatment.
Researchers at Harvard Medical School have made a breakthrough in treating multi-site brain cancers by combining tumor-attacking viruses with an approved chemotherapeutic drug. The treatment works by suppressing the immune system's antiviral response, allowing the virus to selectively kill malignant cells.
Wake Forest University Baptist Medical Center has become the first medical center to use the GliaSite Radiation Therapy System, a device that delivers high doses of radiation directly into tumor tissue. This innovation aims to improve treatment outcomes for patients with malignant brain tumors.
The Pediatric Brain Tumor Consortium, sponsored by the National Cancer Institute, aims to speed the development of innovative treatments for children with brain tumors. The consortium brings together experts from eight institutions to conceive, develop and carry out pilot studies and early trials of promising new therapies.
Researchers have developed a new protein, IL13-PE38QQR, that penetrates brain cancer cells and kills them without harming healthy cells. The protein is a combination of interleukin 13 and Pseudomonas exotoxin, which can be delivered through the skull via a needle, potentially allowing patients to remain awake during treatment.
The study identifies mutations of P-TEN in advanced brain, breast, and prostate cancers, suggesting a new potential target for cancer treatment. The discovery represents one of the first genes implicated in aggressive brain tumors.