Research on diseases of the heart and blood vessels. Covers microvascular imaging, light exposure, cardiac imaging anxiety, and sex differences in risk.
Researchers at the Salk Institute successfully reversed aging signs in middle-aged and elderly mice using a cellular rejuvenation approach. The treatment, which involves reprogramming cells with four specific molecules, restored youthful epigenetic patterns and improved tissue function without increasing cancer risk.
A clinical decision support system was found to lower cardiovascular risk for patients with severe mental illness by providing individualized informational handouts and treatment recommendations. The study suggests that such systems may result in positive impacts on long-term cardiovascular health.
A recent study published in Applied In Vitro Toxicology found that tobacco-free nicotine pouches exhibit reduced levels of toxicants and biological activity compared to combustible cigarette smoke. The products, manufactured by Imperial Brands, showed substantially reduced genotoxicity and cytotoxicity in three toxicological assays.
Researchers have identified a crucial nuclear transport mechanism essential for organ growth and development, involving the protein YAP. The study shows that YAP interacts with importin-7 to control its nuclear entry, regulating cell and tissue growth, and potentially targeting diseases such as atherosclerosis and cancer.
A new study reveals that simultaneous measurement of dozens of types of fats in the blood can predict the risk of developing type 2 diabetes and cardiovascular disease years in advance. The researchers found that individuals with a certain lipid profile are at increased risk, while those with a different profile have lower risk. This d...
A pooled data analysis found that between 30 and 60 minutes of muscle strengthening activity per week is associated with a 10-17% lower risk of death from any cause. The J-shaped curve showed no conclusive evidence that more than an hour of this activity reduces the risk further.
A new collection of scientific articles reviews the past decade of research on women's cardiovascular health, identifying key differences between men and women. The studies highlight critical gaps in current knowledge and emphasize the need for a more tailored approach to diagnosing and treating heart disease and stroke risk in women.
A large study found a significant link between salt-containing paracetamol and an increased risk of heart attacks, stroke, and death. Patients with high blood pressure who took sodium-containing paracetamol had a higher risk of cardiovascular disease and death compared to those taking non-sodium-containing paracetamol.
Researchers at University of Missouri found a long-term association between adolescent psychological well-being and adult cardiovascular disease risk. People who are more optimistic in their youth can lower their chances for heart disease as adults.
Research found that women who experienced sexual violence were more likely to develop high blood pressure over a seven-year period. Women who experienced both sexual assault and workplace harassment had the highest risk of developing high blood pressure.
Researchers discovered specific ceramides in the blood are associated with unfavorable levels of diabetes-related compounds, linking unhealthy diets to increased risk. Ceramide profiling may enable more precise dietary approaches for preventing cardiometabolic diseases.
A large-scale study of 400,000 adults in the UK Biobank found no evidence that eating vegetables reduces the risk of cardiovascular disease. The researchers controlled for various confounding factors and found that any apparent effect was largely due to residual confounding.
A study reveals that changes in gut microbiota and metabolome are associated with cardiovascular disease development, particularly coronary heart disease. The research found that alterations in the gut microbiome occur long before the onset of heart disease, suggesting a potential role for the microbiome in its early pathogenesis.
A new study from the University of Helsinki found that providing individuals with their personal genetic risk for cardiovascular disease motivates them to take better care of their health. The interactive web-tool KardioKompassi helped participants understand their risk and make lifestyle changes.
A Swedish registry study found no increase in endocarditis cases among high-risk individuals since the removal of prophylactic antibiotics in dentistry. The study monitored over 76,000 high-risk individuals and 396,000 low-risk individuals from 2008 to 2018.
Researchers have made a significant breakthrough in predicting heart attacks and strokes by developing a non-invasive method using super-resolution ultrasound imaging. The technology aims to detect high-risk atherosclerotic plaques that are prone to rupture, allowing doctors to prescribe life-saving interventions.
A new 10-year analysis shows that only half of individuals with high blood pressure, high cholesterol, or obesity receive lifestyle support from their GPs. Lifestyle interventions can significantly reduce the risk of cardiovascular disease.
Only 1.9% of Chinese children and adolescents exhibit ideal cardiovascular health status, with socioeconomic factors impacting behavior. Researchers recommend strategies like household smoking control and physical activity promotion to improve cardiovascular health in young generations.
A new study found that statin intolerance is over-estimated, affecting only 6-10% of patients worldwide. Researchers identified risk factors for statin intolerance, including age, sex, ethnicity, and medical conditions.
A study by Washington State University found that social support can mitigate the risk of heart disease and death in older American Indians. Higher rates of depression symptoms, poor quality of life, and social isolation were linked to increased mortality, but instrumental social support reversed this effect.
A study of 3099 older Italians found that increasing physical activity levels between 65-75 years old can lower cardiovascular disease risks in late old age. Maintaining an active lifestyle over time was associated with a 52% lower risk of cardiovascular disease among men.
Researchers at Universidad Carlos III de Madrid developed a computer vision system to analyze cells in microscopy videos, allowing for automatic characterization of cell behavior. The system enables faster analysis of thousands of cells compared to traditional methods, which typically involve manual segmentation and tracking.
The American Roentgen Ray Society has awarded two 2022 ARRS Scholarships to Sean Woolen and Bradley Allen, providing a total of $180,000 in funding for their radiological research projects. The scholarships aim to advance emerging scholars and prepare them for leadership positions.
A new study finds that women with a history of gestational diabetes are at greater risk for a range of cardiovascular conditions, including coronary artery disease and heart failure. The research, which analyzed data from 219,330 women, suggests that preventative measures during pregnancy may help prevent cardiovascular disease later i...
The University of South Florida has received a five-year, $1.35 million NIH institutional grant to train scientists in vascular inflammation and injury research. The grant will support the comprehensive training of pre- and postdoctoral scientists focused on this emerging area of research.
Researchers found that young adults with cannabis use disorder are more likely to experience recurrent strokes compared to those without the condition. The study suggests that chronic marijuana use may impair blood vessel function and increase the risk of future strokes.
A study examining national data of adults aged 60 and older found that smoking is strongly linked to poor brain health, independent of other medical conditions. Smoking was associated with lower cognitive test scores in this population.
New research reveals that one in three US stroke survivors experience food insecurity, which can exacerbate cardiovascular disease and stroke risk. Healthcare professionals can play a crucial role in addressing food insecurity by engaging with patients and providing support or resources.
A new scoring system using data from the American Heart Association's COVID-19 Registry predicted the risk of stroke among adults hospitalized with COVID-19. The study found that six clinical factors, including age, medical conditions, and vital signs, helped identify patients at increased risk of stroke.
A study of over 64,700 Black adults found that those born in the US had a higher rate of death from cardiovascular diseases and all causes compared to those born in other countries. The researchers suggest that early migration may have a 'carryover' effect on mortality rates.
A study examining the health records of 37,379 Medicare beneficiaries found that older adults are at the highest risk of stroke within the first three days after COVID-19 diagnosis. Vaccination and other preventive measures can help reduce this risk.
The ACC cardiooncology course is designed to educate clinicians on improving awareness, identification, monitoring, and management of cardiovascular diseases in cancer patients. The course aims to help clinicians minimize cardiotoxicity from cancer therapies, leading to improved overall survival and quality of life for oncology patients.
A study of 57,000 older US women found that social isolation and loneliness are associated with an increased risk of cardiovascular disease. The researchers also discovered that this risk is highest for women who experience persistent loneliness over time.
A UMass Amherst study found associations between oral contraceptive use and certain tubal ligation methods with lower levels of antimüllerian hormone (AMH), a biomarker for ovarian aging. This may suggest an increased risk for early menopause in women who have used oral contraceptives or undergone specific types of tubal ligation.
A new study reveals that social isolation and loneliness can increase cardiovascular disease risk by 8% and 5% respectively. Women who experience high levels of both social isolation and loneliness have a 13-27% increased risk of heart disease, compared to those with low levels.
A study led by Ohio State University Wexner Medical Center finds that Black patients with dilated cardiomyopathy have a higher risk of family members being affected. The research analyzed data from 1,220 patients and their relatives, revealing that 39% of Black patients had at least one first-degree family member with the condition.
Researchers have discovered a new method to predict heart attacks by analyzing the gene expression of foamy macrophages, revealing a person's cardiovascular health. The study found that foamy cells can be both beneficial and detrimental depending on their behavior in individuals with certain conditions.
A new study published in Clinical Nutrition found that drinking less than the UK's recommended 14 units of alcohol per week increases the risk of cardiovascular events. Moderate alcohol consumption is associated with a 23% increased risk of suffering a cardiovascular event for every additional 1.5 pints of beer consumed.
A recent review highlights the potential of structural proteomics in understanding pathological processes and predicting drug candidates for neurodegenerative diseases. The field combines protein chemistry and mass spectrometry to determine protein structure and interactions, which can lead to breakthroughs in treating serious health c...
A new study found that patients with chronic non-communicable diseases are more than twice as likely to die from any cause if they also have a psychiatric comorbidity. Comorbid psychiatric disorders were associated with higher all-cause mortality rates, ranging from 5.5-21.1%.
A new study found a strong association between social determinants of health and obesity rates, with higher SDOH burden leading to increased obesity prevalence. The study analyzed data from nearly 165,000 adults in the US and found that middle-aged and non-Hispanic Black adults were more likely to be overweight or obese.
Common chronic conditions like high cholesterol, pulmonary diseases, and anxiety disorders saw significant declines in new diagnoses during the COVID-19 pandemic. A substantial increase in primary care physicians, face-to-face visits, and proactive care is needed to address this decline and prevent poor health outcomes.
Researchers developed an AI system that can analyze retinal scans to identify patients at high risk of a heart attack over the next year. The system uses deep learning techniques and achieves an accuracy of 70-80%, revolutionizing the way patients are screened for signs of heart disease.
Researchers found minority groups were less likely to start newer diabetes medications, despite needing them most. The study used data from nearly 5,000 patients with type 2 diabetes and showed Black patients were 20% less likely and American Indian or Alaskan Native patients were 50% less likely to initiate treatment.
Scientists identified 46 metabolites linked to coronary heart disease among Black Americans, which were also found in a multi-ethnic population. These biomarkers may serve as better markers of disease for the general population than traditional risk factors.
Researchers found that Rivaroxaban reduces atherosclerosis progression by inhibiting factor Xa-PAR2 mediated macrophage autophagy and inflammasome activity. The study suggests RIV as a potential anti-atherosclerotic drug, offering hope for treating this fatal disease.
A recent study published in Science Translational Medicine identified a novel causative gene, BAG5, for dilated cardiomyopathy, a leading cause of heart failure. The researchers found that mutations in this gene can lead to cardiomyopathy and found a potential treatment alternative using adeno-associated viruses (AAV) gene therapy.
Researchers found rural patients with acute cardiovascular conditions are less likely to receive important procedures and treatments, resulting in higher mortality rates. The study highlights the need for public health and policy efforts to improve rural healthcare outcomes.
A University of South Australia study suggests that nature-based citizen science projects can alleviate stress and isolation, while improving mental, emotional, and physical health benefits. By engaging with natural environments, individuals can experience lower stress levels, improve their wellbeing, and feel connected to a community.
Researchers at La Jolla Institute for Immunology found that macrophages in artery walls can sense octanal, leading to inflammation and atherosclerosis. By blocking this detection, they reversed disease progression. Further research is needed to explore the role of olfactory receptors in cardiovascular diseases.
Researchers found that women who experienced childhood sexual abuse developed blunted cortisol profiles, associated with health problems like depression and anxiety. Epigenetic age acceleration also contributed to these effects. The study aims to understand resilience to trauma and develop interventions for those affected.
A study suggests that nearly 60 percent of the risk associated with coronary artery disease may be explained by changes in hundreds of genes working together in networks across several organs. Fat processing hormones may play a central role in coordinating this activity.
A meta-analysis found that breastfeeding significantly lowers a mother's risk of developing cardiovascular disease, including heart attacks and strokes. The review analyzed health data from nearly 1.2 million women across eight studies conducted in different countries.
A study reveals a powerful subset of vascular macrophages expressing CLEC4A2 fosters 'good' macrophage behavior, limiting plaque build-up. This discovery challenges the widely held belief that macrophages only play a harmful role in cardiovascular disease.
A bioengineer at Northern Arizona University received a $507,642 NSF CAREER grant to improve cardiovascular flow computer models using machine learning. The project aims to develop software that synergistically integrates deep learning and traditional physics-based modeling to address fundamental issues in high-fidelity blood flow and ...
The International Cardiac Rehabilitation Registry (ICRR) is designed to assess the quality of cardiac rehab programs worldwide, improving patient outcomes. The registry enables programs in low- and middle-income countries to benchmark their services against international standards.
A study identified factors at midlife associated with a decline in women's physical health 10 years later. Higher body mass index, smoking, osteoarthritis, and depressive symptoms were found to be significantly linked to clinically important declines in physical health.
A study found that consuming more than 7 grams of olive oil per day is associated with lower risk of cardiovascular disease, cancer, neurodegenerative, and respiratory disease mortality. Replacing margarine, butter, mayonnaise, and dairy fat with olive oil was also linked to improved health outcomes.
A new UCLA-led study suggests that switching from cigarettes to smokeless tobacco can lower levels of inflammation and oxidative stress biomarkers, which predict cardiovascular disease risk. This finding implies that exclusive smokeless tobacco users have similar biomarker levels to 'never' smokers.
Researchers at Boston Medical Center created a new resource to manage long-term heart disease risk after specific pregnancy complications. The review synthesizes recommendations for primary care clinicians to assess and manage risk, focusing on preeclampsia, gestational diabetes, and preterm delivery.