Articles tagged with Cardiovascular Disease
A new study by the Keck School of Medicine of USC finds that Medicaid expansion is associated with a significant reduction in mortality rates. The study, which tracked data from 2014-2018, found that expanding Medicaid coverage resulted in an estimated 3.8% decrease in adult deaths per year.
Researchers found that increased physical activity reduced mortality risk in all groups, but health benefits plateaued in healthy individuals and those with cardiovascular risk factors. In contrast, cardiovascular disease patients showed no further benefit beyond a certain volume of physical activity.
A UC Riverside-led study found that dicyclohexyl phthalate, a common plasticizer, increases plasma cholesterol levels by binding to the pregnane X receptor, or PXR. The study suggests that PXR activation contributes to the harmful effects of plastic-associated chemicals on cardiovascular health.
A new American Heart Association scientific statement highlights how major life events, such as starting school or entering retirement, can negatively impact physical activity levels and heart health. The statement emphasizes the need for proactive measures to address this issue and provides guidance for healthcare professionals to pro...
Researchers at Karolinska Institutet found a strong link between the apoB/apoA-1 ratio and cardiovascular disease. Individuals with higher ratios had a greater risk of severe cardiovascular disease, including myocardial infarction and stroke.
A novel detection system has been developed to detect skin cholesterol, providing a non-invasive method for long-term lipid management of cardiovascular diseases. The system uses fluorescent reagent to bind to skin cholesterol, allowing for accurate measurement of cholesterol content.
A study by the Istituto Neurologico Mediterraneo Neuromed I.R.C.C.S. found that consuming ultra-processed foods significantly increases the risk of a second heart attack or fatal stroke in people with cardiovascular diseases, even if they follow the Mediterranean diet.
A study conducted at the University of Jyväskylä found that physically active lifestyle mitigates unfavourable changes in metabolic health during menopause. Menopausal transition is associated with increased abdominal fat mass, blood pressure, and blood glucose levels.
A new study from the University of Eastern Finland found that patients with type 2 diabetes often do not receive adequate cholesterol-lowering treatment, despite guidelines recommending statin prescriptions for elevated LDL-C levels. Women tend to have higher average LDL-C levels and receive less statin treatment than men.
Research from Harvard University reveals that physical activity later in life shifts energy towards mechanisms that extend health, reducing chronic illnesses. The study highlights the importance of staying physically active as we age to allocate energy to physiological processes that slow down deterioration.
A nationwide observational study published in Circulation found that lower levels of income and education are associated with reduced chances of survival after out-of-hospital cardiac arrest. The study analyzed data from 31,373 cases of OHCA between 2010 and 2017, showing a correlation that was observed in both men and women.
A novel detection system developed by Chinese researchers can non-invasively detect skin cholesterol levels, a close proxy for LDL-C and apoB serum measurements. This innovation may help long-term lipid management of CVDs, providing an alternative to invasive blood lipid detection methods.
Extreme heat events are associated with a greater risk of death from ischemic heart disease, stroke, and heart failure. Preventive strategies aim to reduce hyperthermia and dehydration to minimize cardiovascular risk during extreme heat events.
Researchers found that cerebral palsy patients with low muscle mass often have inaccurately calculated kidney function, leading to missed diagnoses of advanced kidney disease. This association increases the risk of cardiovascular disease and mortality in this population.
A recent study published in Hypertension suggests that adolescent arterial stiffness may increase the risk of systolic and diastolic hypertension by 20% and 2-fold, respectively, seven years later. Higher arterial stiffness levels were also associated with an increased risk of abdominal and whole-body obesity.
A recent study published in Circulation found that patients receiving a combination of antiplatelet drugs for many months (up to 2.5 years) after stent procedures may not receive the full benefit of treatment. The researchers compared characteristics of 8,864 patients from an older trial to 568,540 contemporary patients and determined ...
The European Society of Cardiology has published guidance for diagnosing and managing cardiovascular disease in patients with COVID-19. The two-part document provides practical information and advice to help clinicians care for patients affected by the pandemic.
Recent clinical and experimental data suggest that vascular calcification and bone loss share common pathophysiological mechanisms. The International Osteoporosis Foundation's new review elucidates the key associations between the two disorders.
A new UCL-led study found that people who survived childhood cancer have a higher risk of cardiovascular disease, infections, and disorders of the immune system by age 45. The study also suggests that cancer survivors treated with chemotherapy and radiotherapy face greater long-term health effects.
A NIH-funded study found that patients with a two-step surgical approach for 'leaky heart valves' had better short-term outcomes, but were more likely to need a pacemaker. The procedure involved repairing the tricuspid valve at the time of mitral valve surgery, and results showed reduced risk of death, reoperation, or severe regurgitat...
A new study by Intermountain Healthcare finds that nearly 40% of patients reported new or continuing symptoms of depression during the pandemic. This increase in depression was associated with higher emergency department visits for anxiety and chest pain, highlighting the negative impact of the pandemic on physical and mental well-being.
A Cleveland Clinic study shows that bariatric surgery significantly lowers the risk of progression to cirrhosis, liver cancer, or liver-related death. Bariatric surgery also reduces the risk of developing serious cardiovascular diseases such as heart attack and stroke.
A study of 35 low- and middle-income countries found that less than one-third of individuals with high cholesterol received treatment. This highlights the inadequate care for hypercholesterolemia in these regions, a major risk factor for cardiovascular disease.
Two leading US physicians urge doctors to screen patients for exposure to indoor and outdoor air pollution, recommending interventions to limit exposure and improve cardiovascular health. Governments also have a primary responsibility to adopt technologies and regulations that reduce air pollution.
Pollution has been linked to nine million deaths worldwide in 2019, with five million due to cardiovascular disease. The researchers emphasize the need for individual physicians to consider pollution as a risk factor when treating patients, and advocate for government-supported interventions to reduce exposure.
Primary care practices showed significant improvements in cardiovascular quality measures after receiving QI training. The study suggests that light facilitation can support important changes in small practices, leading to better patient outcomes.
A study by Karolinska Institutet found that low levels of microRNA-210 in red blood cells cause vascular damage in type 2 diabetes. The reduction in microRNA-210 levels impaired blood vessel endothelial cell function and led to increased risk of cardiovascular disease.
A new study tracked the spread of a genetic mutation that causes young-onset heart arrhythmia across continents over centuries. The research found that the mutation was passed down from Northern Europe to other parts of the world through migration, and identified a specific gene, KCNQ1, as the cause of the disease.
A study published in The Lancet found that using physiologic measurement quantitative flow ratio (QFR) for lesion selection during percutaneous coronary intervention (PCI) leads to better clinical outcomes compared to standard angiography-guided strategies. This is due to fewer procedural complications and superior long-term results.
A study found that consuming high amounts of herbs and spices daily can lead to significant reductions in systolic and diastolic blood pressure. The researchers discovered that adding just 1.3 teaspoons of herbs and spices a day to an average American diet resulted in lower blood pressure after four weeks.
A study found that Hispanic adults with peripheral artery disease are 80% more likely to access inpatient care through the emergency room, leading to longer and more costly hospitalizations. This disparity highlights the need for improved outpatient care and education among this population to manage PAD effectively.
Research supports strong relationship between ceramides and diseases in animals and humans. Ceramides are standalone biomarkers of cardiovascular disease, independent of cholesterol.
A study found that cardiopulmonary exercise testing is highly applicable for early detection of respiratory disorders in obese individuals. The test assesses physiological responses to exercise and identifies potential issues before symptoms appear.
Researchers at Penn Medicine have made a major advance in understanding dilated cardiomyopathy (DCM), a common and fatal heart disorder. The largest single cause of DCM involves the mutation of the gene that encodes titin, leading to abnormalities in heart muscle cells.
A recent study published by The Menopause Society suggests that eating alone may contribute to an increased risk of heart disease in older women. Older women who eat alone have poorer nutritional knowledge and intake, as well as a higher prevalence of angina, a type of chest pain caused by reduced blood flow to the heart.
Women face unique socioeconomic barriers that set back their cardiovascular health early in life, increasing risk of heart attack and stroke. These disparities can be mitigated through policy changes, community support, and diversification within the cardiology workforce.
The COVID-19 pandemic has sharply curtailed scientific research globally, with nearly all labs closing in 2020 and many clinical trials halted. The American Heart Association calls for increased federal funding to rebuild the research enterprise, targeting early career investigators, women, and underrepresented groups.
A new canine mutant model mimics human cerebrovascular disease by exhibiting severe arteriosclerosis, thrombosis, and stroke. The ApoE knockout dogs show extensive and severe arteriosclerosis plaques and arterial stenosis, consistent with human cerebral arteries and coronary arteries.
The MIPACT study analyzed data from thousands of participants, revealing differences in heart rate, blood pressure, and activity levels by age, race, ethnicity, and clinical conditions. The study's findings have significant implications for clinicians, providing a more complete picture of daily life and resulting health.
A recent study has discovered genetic markers associated with high levels of lipopolysaccharide (LPS) in the blood, a toxin linked to sepsis and cardiovascular diseases. The research also found a connection between LPS levels and blood coagulation disorders, such as thromboembolism and stroke.
Researchers create maps of senescence in heart and lung cells, comparing different types of senescent cells across the lifespan. The goal is to understand how senescent cells contribute to age-related diseases and develop therapies called senolytics.
Research links Social Vulnerability Index scores with higher rates of cardiovascular disease death in young and middle-aged adults. The study highlights the urgent need for tailored interventions to address social risks in socially vulnerable communities.
A recent review published in the Journal of the American Heart Association found that flu vaccination can significantly reduce the risk of heart attack and stroke in individuals with heart disease. Despite higher mortality rates from influenza, many Americans under 65 with heart disease have low vaccination rates.
Researchers have discovered three new genetic variants linked to fibromuscular dysplasia, which affects women in their prime and is often associated with high blood pressure and cardiovascular complications. The study provides new insights into the disease's genetic basis and potential therapeutic targets.
Researchers found that regular cycles of a fasting-mimicking diet in mice helped counteract the negative effects of a high-fat, high-calorie diet. The study suggests that this diet may have potential as 'medicine' to prevent obesity and heart disease.
The study provides a unique genomic blueprint for understanding the complex mechanisms linking obesity with comorbidities like type 2 diabetes and cardiovascular diseases. The Ossabaw pig's genome is highly relevant to humans, making it an ideal model for studying human obesity.
A large population study found that statin treatment was associated with a slightly lower risk of dying from COVID-19. The results suggest a moderate prophylactic effect on mortality, supporting the continued use of statins for conditions like cardiovascular disease and high blood lipids.
A study published in the European Heart Journal found that increasing steps per day, moderate-to-vigorous physical activity, or reducing sedentary time can improve cardiorespiratory fitness. Individuals with higher-than-average activity levels had better fitness regardless of sedentary time spent.
A new study found that women whose menstrual cycle length increased two years before menopause had better vascular health than those with stable cycles. Changes in cycle length may predict cardiovascular disease risk, allowing clinicians to recommend preventive strategies.
A high intake of alpha linolenic acid (ALA), found in nuts, seeds, and plant oils, is associated with a lower risk of death from all causes and diseases of the heart and blood vessels. However, further studies are needed to confirm the association with cancer mortality.
A recent study published in the American Journal of Clinical Nutrition found that consuming whole fat milk has no negative impact on children's health. The research, which involved 49 healthy children aged four to six, showed that both groups consumed similar amounts of calories and fat.
A study published by the American College of Cardiology found a significant inverse relationship between oral health and COVID-19 severity, as well as delayed recovery and increased inflammation in patients with cardiovascular diseases. Researchers recommend maintaining good oral hygiene to prevent or decrease COVID-19 disease severity.
Researchers found a chemical inhibitor of PDE9 stimulates cells to burn more fat in mice, reducing obesity and fatty liver. The study's findings suggest the experimental drug may be effective in treating severe obesity and improving heart function.
Researchers at the University of Surrey discovered that red blood cells generate an electric field voltage outside and not just within biological cells. This has significant potential implications for future medical treatments, particularly in cardiovascular disease, cancer, and fertility treatment.
A new study published in the Journal of the American Heart Association found that long-term exposure to air pollution and road traffic noise may be associated with an increased risk of developing heart failure. The correlation appears to be greater in people who are former smokers or have high blood pressure.
The Rutgers-NYU Center for Asian Health Promotion and Equity aims to address significant disparities in the Asian community's relationship with heart health and mental health. The center will focus on cardiometabolic disease and mental health research to inform practice and policy at local, regional, and national levels.
Scientists at Karolinska Institutet have discovered a carbohydrate called mannose as a biomarker for severe COVID-19 disease severity. The study found that glycolysis and glutaminolysis play a crucial role in SARS-CoV-2's spread and growth, providing potential new therapeutic strategies.
The ACC Middle East 2021 conference will showcase the latest evidence-based strategies for improving heart health in the Middle East. The event features presentations from renowned experts on the most impactful clinical trials and contemporary best practices in treating cardiovascular disease.
Researchers have found a specific protein, circulating fatty acid synthase (cFAS), in the blood that can accurately detect severe peripheral artery disease and narrow the arteries in the legs. The study suggests that cFAS may contribute to plaque formation characteristic of cardiovascular disease.
A Canadian study found a significant decrease in cardiac procedures during the pandemic, resulting in higher wait list mortality rates. Despite no increase in wait times, patients with heart disease were at higher risk of dying while waiting for their procedure.