Articles tagged with Cardiovascular Disease
Scientists at UCSF have shown that gene-edited cellular therapeutics can effectively treat major diseases such as peripheral artery disease, chronic obstructive pulmonary disease, and heart failure. The study used specially engineered induced pluripotent stem cells called HIP cells to evade the immune system.
Regularly consuming a Southern-style diet characterized by added fats, fried foods, eggs, organ meats, processed meats, and sugar-sweetened beverages may increase the risk of sudden cardiac death. In contrast, following a Mediterranean diet high in fruits, vegetables, fish, whole grains, and legumes can decrease this risk.
A recent study published in Chinese Medical Journal found that maintaining normal blood pressure over a long period of time significantly reduces the risk of cardiovascular disease. The study analyzed data from a 26-year follow-up of participants and found that cumulative blood pressure levels were a reliable measure of the risk of CVD.
A Finnish-English study published in the Lancet Digital Health found that accelerating risk factor changes can identify high-risk individuals, who may lose 2 to 6 life-years if preventive measures are delayed. An online tool has been developed to study the impact of risk history on estimated cardiovascular disease risk.
Researchers successfully engineered yeast to produce spermidine, a natural molecule that induces autophagy, in hopes of addressing age-related diseases. The production yield reached 2.3 grams per liter, paving the way for fermentation-based manufacture of polyamines and their analogues.
A recent Finnish study found that higher levels of moderate and vigorous physical activity can reduce arterial stiffening in childhood. The study, which followed 245 children aged 6-8 years over two years, showed a positive association between increased physical activity and more elastic arteries.
A study published in Atherosclerosis has found that the build-up of calcium in major blood vessels is linked to a 39% higher risk of serious falls in older women. The research used bone density scans to identify abdominal aortic calcification, which can be detected early on, and may help health professionals to prevent future falls.
Researchers found that mutations in cardiac myosin-binding protein C (cMyBP-C) cause HCM through unknown mechanisms, altering protein integrity or mechanical properties. This knowledge is crucial for clinical follow-up and treatment of patients and their families.
Researchers have developed a new AI-powered diagnostic tool using electrocardiograms (ECGs) to diagnose coronary artery disease, myocardial infarction, and congestive heart failure. The tool achieved an accuracy of over 98.5% in classifying patients' ECG signals.
A recent study published by the American Society for Nutrition compared the effects of low-fat and plant-centered diets on cardiovascular health. The research found that a plant-centered diet was associated with a lower long-term risk for cardiovascular disease, although both diets were linked with lower LDL levels.
Research led by Dr. Satya P. Kunapuli seeks to understand how platelets become activated to form clots that lead to cardiovascular diseases like stroke and heart attack. The study aims to identify molecular differences in platelet genes and proteins to facilitate the discovery of new signaling pathways relevant to cardiovascular disease.
A new study from the University of South Australia found that regular milk consumption is associated with a lower risk of heart disease. The research, which analyzed genetic biomarkers in over 400,000 people, suggests that milk's calcium content may contribute to improved cholesterol levels and reduced cardiovascular risk.
A nationwide study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a plant-based dinner can significantly reduce the risk of heart disease. The study, which analyzed data from over 27,000 U.S. adults, discovered that individuals who consumed more whole carbohydrates and unsaturated ...
A new study published in the Journal of the American College of Cardiology found that a diet proven to lower elevated blood pressure, known as the DASH diet, reduces inflammation and heart injury. The findings also showed that a low-sodium diet can improve cardiovascular risk factors in a relatively short time period.
A Rensselaer-developed deep learning algorithm can identify patients at risk of cardiovascular disease using low-dose CT scans used for lung cancer screening, potentially expediting diagnoses and accelerating treatments.
Research presents evidence that social isolation and loneliness are associated with a higher risk of cardiovascular disease in post-menopausal women. The study found that measures of social isolation and loneliness should be incorporated into standard care to better understand cardiovascular risk and develop solutions.
The Lancet Commission report outlines 10 recommendations to improve health outcomes for millions of women worldwide and achieve the global targets set. The report aims to reduce the global burden of cardiovascular conditions in women, including heart disease and stroke, which account for 35% of deaths.
A TGen-led study of 70,000 individuals found that both smoking and cardiovascular disease impair verbal learning and memory in adulthood, with sex differences observed. The study suggests that quitting smoking can improve brain function and maintaining cardiovascular health is crucial for preventing cognitive decline.
Smaller, solo practices that made operational changes, such as training medical assistants for accurate blood pressure readings, saw substantial improvements. Practice facilitation was crucial, with larger practices requiring more facilitation to achieve meaningful gains.
A new study published in JAMA Network Open found that patients with heart disease are less likely to receive cholesterol-lowering statin prescriptions later in the day, particularly after 12 pm. The odds of prescription decreased progressively throughout the morning and remained low throughout the afternoon.
A new study found that vegetarians had significantly lower levels of 'bad' cholesterol and higher levels of beneficial biomarkers like HDL cholesterol. However, they also had higher levels of fats and poorer kidney function markers, suggesting a more complex relationship between diet and health.
Researchers created a probe that glows when detecting an enzyme associated with blood clots and strokes. The probe, made up of two components, can host fluorescent molecules and detects an increase in fluorescence intensity when the probe comes into contact with the enzyme.
A study of over 5,000 couples found that individuals with a spouse who has heart disease are more than twice as likely to have heart disease themselves. Lifestyle factors such as physical activity, smoking, and alcohol use, as well as caregiver stress, were also identified as contributing to this increased risk.
A large study of 345,000 people from 48 trials found that blood pressure-lowering medication lowers the risk of cardiovascular events by around 10% regardless of starting blood pressure level. The research calls for global guidelines to be changed so that anyone with increased risk of cardiovascular disease is considered for treatment.
Research shows that physically active individuals who reach 100 PAI points per week have a lower risk of excessive weight gain. The study, which tracked over 85,000 healthy Norwegians for 20 years, found that maintaining at least 100 PAI points per week can help prevent unhealthy weight gain.
A new study found that people living near fracking sites are at a higher risk of heart attacks, with rates increasing by 1.4-2.8% depending on age group and level of activity. The research also highlights the potential negative impact of fracking on cardiovascular health in rural communities.
Researchers found that duloxetine inhibited platelet function and protected against clot formation, potentially benefiting patients with both depression and cardiovascular disease. The study aims to develop new drugs based on the structure of duloxetine to protect from thrombosis.
Researchers identified two dietary patterns associated with an increased risk of cardiovascular disease and death in middle-age. The first pattern includes high intakes of chocolate, confectionary, butter, and white bread, while the second is characterized by high sugar-sweetened beverages, fruit juice, and preserves.
A recent study published in the European Heart Journal has found a clear link between disrupted sleep and an increased risk of dying from diseases of the heart and blood vessels, as well as death from any cause. Women were found to have nearly double the risk of cardiovascular death compared to men.
New research suggests that HDL particles' anti-inflammatory properties may predict future cardiovascular events, improving risk assessment and prediction. The study found that individuals with lower anti-inflammatory activity in their HDL particles were more likely to experience cardiovascular events.
Researchers found that almonds contain approximately 20% unabsorbed calories after digestion, which can result in reduced energy absorption and potential weight loss. This finding could alleviate concerns about nuts contributing to weight gain, allowing for healthier snacking options.
Research supports health benefits of breastfeeding by linking it to lower visceral and pericardial fat volumes. Lactation duration is associated with a 50% lower relative risk of progression to Type 2 diabetes in women, independent of their metabolic profiles and body size before pregnancy.
A University of Gothenburg study found a significant increase in heart failure and stroke cases among men under 40 in Sweden, attributed to rising obesity rates and declining physical fitness. The study monitored over 1.2 million men for 20 years, revealing a sharp decline in heart attacks despite increasing obesity.
A clinical practice review article by Rita Kalyani provides a systematic approach for treating patients with diabetes and cardiovascular disease. The article recommends using GLP-1 receptor agonists and SGLT2 inhibitors, particularly for patients with heart or blood vessel disease, to reduce the risk of major cardiovascular events.
Women with cardiovascular disease require reproductive planning to ensure optimal health and minimize risks during pregnancy. The American College of Cardiology emphasizes the importance of sharing decision-making with healthcare providers to create an action plan for contraception and medical decision-making.
Researchers have developed a way to restore dysfunctional lymphatic networks using hydrogels made from hyaluronic acid. This allows the body to better defend itself against diseases such as cancer, cardiovascular disease, and diabetes. The study's findings have been published in The FASEB Journal.
A global study of 134,297 people from 21 countries found that consuming 150g or more of processed meat per week increased the risk of cardiovascular disease by 46% and mortality by 51%. Moderate consumption of non-processed meats had a neutral effect on health.
A multinational study published in The American Journal of Clinical Nutrition found that consuming moderate amounts of unprocessed meat is okay, but processed meats should be avoided. Higher processed meat intake was associated with higher risks of total mortality and major cardiovascular disease.
Researchers have identified a genetic link to clogged arteries, finding that a specific gene variant increases the risk of coronary artery disease, high blood pressure, and diabetes. The discovery provides new insights into the causes of cardiovascular disease and offers potential therapeutic targets for treatment.
A recent review article published in Chinese Medical Journal explores the associations between psoriasis treatments and risks of cardiovascular diseases. The study finds that some treatments, such as TNF-α inhibitors and methotrexate, may reduce long-term cardiovascular risk, while others, like IL-12/23 inhibitors, may increase it.
A nationwide study of nearly 1.5 million people found that increasing physical activity in low-to-moderate air pollution areas reduced cardiovascular disease risk by 27%, while decreasing activity increased the risk. In contrast, high air pollution levels saw an increased risk when physical activity exceeded recommended levels.
Researchers examine the use of left atrial function indexes to evaluate left atrial function in cardiovascular disease. The study highlights their effectiveness in risk stratification and prognosis for conditions like heart failure and coronary heart disease.
Researchers used wearable data to predict functional capacity and frailty in cardiovascular disease patients. The study found that wearable activity data was a reliable indicator of these factors, allowing for earlier intervention and improved patient outcomes.
Women who experience a miscarriage are more likely to die prematurely due to cardiovascular disease. Research found that miscarriages, especially those occurring early in life or recurrently, can signal an increased risk of premature health risks.
A recent Finnish study found that accumulating brisk and vigorous physical activity can curb adiposity-induced low-grade inflammation in children. The study, conducted among researchers from Finland and the UK, also reported no independent association between diet quality and low-grade inflammation.
A study found that higher consumption of ultra-processed foods is associated with an increased risk of cardiovascular disease incidence and mortality. Researchers analyzed data from the Framingham Offspring Study and classified food items into five categories, including ultra-processed foods, which were linked to a 7% increase in hard ...
A study published in The Endocrine Society's annual meeting found that genetic risk factors for PCOS are associated with obesity, diabetes, cardiovascular disease, and male-pattern baldness in men. This suggests that at least some cases of PCOS may be caused by biological mechanisms common to both men and women.
A new study found that cancer survivors have a significantly higher risk of cardiovascular disease in the next decade. Researchers estimate that about 8% of cancer survivors will develop heart disease or stroke over the 10-year period, compared to 5% of those without a cancer history.
A new study published in Nature Medicine has identified key risk factors that increase the likelihood of individuals developing multiple non-communicable diseases. The analysis found that underlying biological links exist in individuals with multimorbidity, which is a growing public health challenge. The researchers also identified pot...
Patients with kidney disease who exercised regularly had lower rates of death, heart problems, and end-stage renal disease. The study found that moderate-intensity exercise (150 minutes/week) provided the most health benefits.
Researchers found a significant association between COVID-19 and hospital admissions for noncommunicable diseases, including abnormal tissue growths, metabolic diseases, cardiovascular diseases, and musculoskeletal diseases, in São Paulo, Brazil.
A study led by McMaster University found that consuming oily fish regularly reduces the risk of cardiovascular events like heart attacks and strokes by about a sixth in high-risk individuals. The critical ingredient is omega-3 fatty acids, which provide significant protection against cardiovascular disease.
A new study from The George Institute for Global Health found that countries are wasting resources by treating only one aspect of cardiovascular disease, rather than looking at the big picture. The researchers discovered a higher risk of CVD in lower educated and non-employed people, as well as an underuse of medicines in those at high...
Measures of kidney function, such as the urinary albumin-to-creatinine ratio and estimated glomerular filtration rate, may improve estimates of future cardiovascular disease risk. The addition of these non-traditional risk factors could refine stratification and predict cardiovascular disease more accurately.
A study found that county-level factors, such as demographics and socioeconomic conditions, significantly impact cardiovascular disease death rates among different racial and ethnic groups. Black adults had the highest average death rate, while socioeconomic concerns explained much of the variation in death rates among this population.
A study published in EClinical Medicine found a correlation between retinal ischemic perivascular lesions and increased risk of cardiovascular disease. Researchers identified this mark in patients who underwent optical coherence tomography scans, suggesting it could serve as a biomarker for heart disease.
Researchers at Massachusetts General Hospital found that atherosclerosis can accelerate the development of clonal hematopoiesis. Clonal hematopoiesis is an age-related condition where descendants of one hematopoietic stem cell dominate blood cells.
Hypertrophic cardiomyopathy (HCM) is a complex disease characterized by thickening of the left ventricle. Researchers have identified patient-specific protein networks using RNA-seq and tissue samples from HCM patients. This study offers a path toward individualized medicine for treating HCM.
Researchers at the University of Alberta identified a new mechanism responsible for plaque buildup on artery walls, which can restrict blood flow and lead to cardiovascular disease. They found that inhibiting this process with specific drugs could be a new strategy for treating cardiovascular disease.
Postmenopausal women who consumed high levels of plant protein had a 9% lower risk of all-cause death and a 21% lower risk of dementia-related death compared to those with the lowest intake. Higher consumption of processed red meat was associated with a higher risk of dementia.