Add BrightSurf on Google Email

Study links residual inflammation in psoriasis patients to obesity and fatty liver disease

Researchers found that residual inflammation in psoriasis patients is linked to obesity, metabolic dysfunction, and increased systemic inflammation. This study suggests that despite good skin response to biologics, patients may still exhibit broader health implications, such as cardiovascular disease and fatty liver disease.

SourceElsevier·JournalJournal of Investigative Dermatology·TypeObservational study·DateMay 20, 2025

Researchers discover why donor hearts fail in cold storage — and how to prevent it

A new molecular process discovered by researchers contributes to the failure of donor hearts after transplant, but a therapy using medication for high blood pressure has been found to reduce damage. The treatment significantly improves the function of donor hearts and increases their distance in cold storage.

SourceMichigan Medicine - University of Michigan·JournalNature Cardiovascular Research·TypeExperimental study·DateMay 19, 2025

Semaglutide may provide early protection against heart disease in high-risk patients—even before clinically meaningful weight loss and prior to the full target dose

A new analysis of the SELECT trial shows semaglutide reduces major cardiovascular events by 40% within 3-6 months, even before significant weight loss and full target dose. The study found that semaglutide's effects on reducing inflammation, blood sugar, and blood pressure may contribute to its early clinical benefits.

Biological age predicts cardiovascular disease morbidity and mortality

A multicentre study found that biological ageing, measured by frailty index and telomere length, can predict cardiovascular disease risk more accurately than traditional tools. The study, involving over 14,000 individuals, suggests that incorporating biological age into risk assessments could improve cardiovascular health outcomes.

Family Heart Foundation announces results of real-world study in 273,770 individuals with cardiovascular disease demonstrating that risk of subsequent cardiovascular event increases with rising lipoprotein(a) levels

A study of 273,770 individuals with cardiovascular disease found that increasing lipoprotein(a) levels significantly increases the risk of subsequent cardiovascular events. Treatment with high-impact LDL-C lowering therapies may help reduce this risk.

SourceFamily Heart Foundation·JournalEuropean Heart Journal·TypeData/statistical analysis·DateMay 7, 2025

Long COVID may cause long-term changes in the heart and lungs and may lead to cardiac and pulmonary diseases

Researchers found persistent inflammation in heart and lungs of patients with long COVID, even after standard tests return normal results. This study uses advanced PET/MRI imaging to detect abnormal patterns that could serve as early warning signs of future cardiac and pulmonary conditions.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJournal of Nuclear Medicine·TypeImaging analysis·DateMay 6, 2025

Study links childhood trauma to increased substance use and unexpected effects on heart rate and blood pressure in adolescents

A new study published in the Journal of Child Psychology and Psychiatry reveals that childhood trauma significantly increases the likelihood of engaging in risky behaviors, including harmful alcohol consumption, smoking, and illicit drug use. The research also found an unexpected connection between trauma and cardiovascular health, wit...

SourceUniversity of Bath·JournalJournal of Child Psychology and Psychiatry·DateApr 30, 2025

Heart disease deaths worldwide linked to chemical widely used in plastics

A new analysis of population surveys estimates that exposure to di-2-ethylhexyl phthalate (DEHP) contributed to 356,238 global heart disease deaths in 2018, accounting for 13% of all global mortality. The study also found higher death risks in the Middle East, South Asia, East Asia, and Pacific regions.

SourceNYU Langone Health / NYU Grossman School of Medicine·JournalEBioMedicine·TypeObservational study·DateApr 29, 2025

Simple test could better predict your risk of heart disease

Researchers found that measuring lipoprotein markers in a simple blood test can identify individuals at high risk of cardiovascular disease more effectively. The study analyzed data from over 200,000 people and showed that the total number of 'bad cholesterol' particles is the most important factor to consider when testing for future h...

SourceChalmers University of Technology·JournalEuropean Heart Journal·TypeObservational study·DateApr 28, 2025

New machine algorithm could identify cardiovascular risk at the click of a button

Researchers developed an automated machine learning program to identify potential cardiovascular incidents and fall/fracture risks based on bone density scans. The algorithm shortened screening time and found moderate to high AAC levels in 58% of older individuals, placing them at high risk of heart attack and stroke.

SourceEdith Cowan University·JournalJournal of Bone and Mineral Research·TypeObservational study·DateApr 28, 2025

Drug candidate successfully treats atherosclerosis, fatty liver disease in large mammals

Researchers successfully treated atherosclerosis and fatty liver disease using DT-109 in nonhuman primates, which has potential as a dual therapy for two common conditions. The compound reduced the formation of atherosclerotic plaques and stopped critical processes that lead to vascular calcification.

SourceMichigan Medicine - University of Michigan·JournalSignal Transduction and Targeted Therapy·TypeExperimental study·DateApr 23, 2025

Children face elevated kidney, heart, and gut risks for years after COVID infection

Long COVID can result in significant health risks for young people, including chronic kidney disease, gastrointestinal symptoms, and cardiovascular conditions. Studies found that children with COVID-19 face elevated risks of developing these conditions, even years after the initial infection.

SourceUniversity of Pennsylvania School of Medicine·JournalJAMA Network Open·TypeData/statistical analysis·DateApr 22, 2025

New research lays groundwork for early detection of Alzheimer’s disease

A new study from Columbia University Mailman School of Public Health found significant associations between cognition and established risk factors for Alzheimer's disease in individuals aged 24-44. The researchers used biomarkers related to cognitive impairment and cardiovascular health to predict long-term trajectories of cognitive de...

Preventing onset and development of heart failure with preserved ejection fraction

Researchers discovered a natural mechanism that protects the heart from heart failure with preserved ejection fraction (HFpEF), a serious condition in need of effective treatment. Restoring this mechanism prevents progression of HFpEF and alleviates lipid overload in heart cells, providing molecular evidence for a promising therapeutic...

SourceBaylor College of Medicine·JournalCirculation·TypeExperimental study·DateApr 15, 2025

New analysis underscores health risks of e-cigarettes

A recent study of 249,190 individuals found a significant link between exclusive e-cigarette use and chronic obstructive pulmonary disease (COPD) and hypertension in adults aged 30-70. In contrast, traditional combustible cigarette smoking was associated with increased risks for various cardiometabolic diseases.

SourceJohns Hopkins Medicine·JournalNicotine & Tobacco Research·DateApr 15, 2025

Sleep matters: Duration, timing, quality and more may affect cardiovascular disease risk

A new American Heart Association scientific statement emphasizes the importance of multidimensional sleep health in reducing cardiometabolic risks. The statement reviews evidence on the relationship between sleep and various health factors, including body fat, blood sugar, cholesterol, and blood pressure.

SourceAmerican Heart Association·JournalCirculation Cardiovascular Quality and Outcomes·DateApr 14, 2025

Perspectives on obesity management and the use of anti-obesity medicine

A new study found that both employed people with obesity and employer representatives acknowledge the impact of obesity on future health problems and perceive lifestyle change alongside anti-obesity medications as the most effective approach for maintaining weight-loss reduction. Cost of medication coverage remains a significant barrie...

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalPopulation Health Management·TypeSurvey·DateApr 9, 2025

Genetic predisposition to sedentary behavior increases the risk of cardiovascular diseases

A new study found that genetic predisposition to sedentary behavior is associated with a higher risk of developing the most common cardiovascular diseases. Individuals with the highest genetic predisposition accumulated more daily sedentary time and had a 20% higher risk of cardiovascular diseases.

SourceUniversity of Jyväskylä - Jyväskylän yliopisto·JournalBritish Journal of Sports Medicine·DateApr 8, 2025

Breakthrough gene therapy offers hope for rare, deadly heart disease in young men

A team of researchers has developed a gene-therapy strategy to treat arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly hereditary disease. The treatment, using adeno-associated viruses, improved cardiac function and prolonged survival in mice with ARVC5-like disease.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalCirculation Research·TypeExperimental study·DateApr 8, 2025

Discovery of mitochondrial protein by researchers at Lewis Katz School of Medicine at Temple University opens path to therapeutic advances for heart and Alzheimer’s disease

Scientists have discovered a novel regulator of the mitochondrial sodium-calcium exchanger (NCLX), which helps maintain calcium balance in mitochondria. The discovery of TMEM65 could lead to new therapeutic agents to combat calcium overload associated with heart failure and Alzheimer's disease.

SourceTemple University Health System·JournalNature Metabolism·DateApr 8, 2025

Breakthrough research revolutionizing pulmonary hypertension treatment

A recent study published in the International Journal of Cardiology analyzed data from multiple clinical trials to assess the therapeutic impact of pulmonary artery denervation (PADN) on pulmonary hypertension patients. PADN showed significant reductions in mean right atrial pressure, mean pulmonary artery pressure, and pulmonary vascu...

SourceOchsner Health System·JournalInternational Journal of Cardiology·DateApr 8, 2025

Dietary shift after migration increases cardiovascular risk by altering the composition of an individual's gut microbiome

A study found that migrants experience a 'clear change' in their gut microbiome composition after migration, leading to increased rates of cardiovascular disease. The Amsterdam UMC-led research showed that specific groups of microbes disappear or emerge along the migration axis.

SourceAmsterdam University Medical Center·JournalGut Microbes·TypeObservational study·DateApr 7, 2025

The heart remembers: Scientists describe how early-life cardiac injury in parents influences the development and function of the heart in the next generation

Scientists have discovered that early-life cardiac injury in parents can alter heart development and function in offspring, leading to improved cardiac remodeling and increased blood ejection volume. This finding suggests a potential long-term impact on cardiovascular health.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalCirculation·TypeExperimental study·DateApr 2, 2025

Being physically active, even just a couple of days a week, may be key to better health

New research published in the Journal of the American Heart Association suggests that even sporadic physical activity can have lasting health benefits, making it easier for people to prioritize their well-being amid busy schedules. The study found that completing 150 minutes of moderate to vigorous physical activity per week, regardles...

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateApr 2, 2025