Researchers developed an AI model that can detect coronary microvascular dysfunction using a common electrocardiogram, outperforming previous models in diagnostic tasks. The model can accurately identify a condition often missed in emergency department visits, providing a cost-effective and non-invasive way to diagnose serious heart co...
Researchers have discovered a small RNA molecule that plays a key role in controlling cholesterol production and the development of heart disease. The molecule, tsRNA-Glu-CTC, was found to boost SREBP2 activity, leading to higher cholesterol levels and increased risk of atherosclerosis.
A systematic review of 17 randomized trials found that reducing saturated fat intake lowered all-cause mortality and cardiovascular deaths among high-cardiovascular risk individuals. For people at low to intermediate risk, cutting or replacing saturated fat intake offered little benefit over 5 years. The study suggests that saturated f...
Researchers found that glycation stress, caused by methylglyoxal, promotes aortic stiffening and cellular senescence. Natural compound Gly-Low, containing nicotinamide and alpha-lipoic acid, reversed these effects and reduced stiffness in aging mice.
Research from King's College London reveals that reversing prediabetes through lowering blood sugar levels significantly reduces the risk of heart problems and death. People who achieved remission had a 58% lower risk of cardiovascular death, while those with normalised glucose levels saw a 42% reduction in major adverse events.
A new study found that calcium accumulation in breast arteries and its progression on mammograms can predict future cardiovascular disease. Women with more severe calcification and those whose calcification worsened over time had a higher risk of heart-related events, such as heart attack, stroke, and death.
The Fuster Prevention Forum will teach clinicians effective ways to educate children, parents, and educators in their communities on nutrition, physical activity, and emotional well-being. The program aims to create a culture of prevention and promote sustainable, community-based initiatives.
The American College of Cardiology recommends a standardized front-of-packaging food labeling system to highlight key nutrients, helping consumers make informed dietary choices. The guidance also aims to reduce the risk of cardiovascular disease and promote overall health.
A recent study published in the American Journal of Preventive Cardiology found that only 13% of US adults with cardiovascular disease met optimal LDL-C management, highlighting significant gaps between guideline recommendations and clinical care. The study suggests actionable steps to improve adherence, including increased use of non-...
A large study found that people with type 1 and type 2 diabetes have a higher risk of sudden cardiac death, particularly in younger adults. The research also showed that sudden cardiac death contributes to shorter life expectancy for those with diabetes.
New study finds that even low levels of smoking carry substantial cardiovascular risks, while quitting completely provides the greatest health benefit. The research highlights the complex relationship between smoking history and time since quitting in relation to heart disease and death risk.
A new 10-minute PET-CT scan reveals overactivity in adrenal glands, allowing for precise targeting of treatment. The test has huge potential to completely change the way high blood pressure is diagnosed and treated.
Researchers have identified a distinct type of frailty in younger people driven by cardiovascular and metabolic illnesses, leading to poor outcomes and premature death. The study calls for routine frailty assessments in all heart attack patients, regardless of age.
A Mayo Clinic study found that nearly 90% of people with the inherited condition familial hypercholesterolemia would not have been flagged for standard genetic testing. This condition can cause dangerously high cholesterol and early heart disease, making it highly treatable yet often undiagnosed.
Researchers found that eating a Mediterranean diet with moderate portions of lean beef did not increase blood levels of trimethylamine N-oxide (TMAO), an emerging indicator of cardiovascular disease risk. This suggests that dietary quality is more important than the amount of beef eaten in relation to heart health.
SourcePenn State·JournalJournal of the American Heart Association·TypeRandomized controlled/clinical trial·DateNov 18, 2025
A Cochrane review found that low-dose colchicine reduced heart attacks and strokes in people with a history of heart disease or stroke. The study involved nearly 23,000 participants and showed that taking colchicine could prevent about two of each heart attack and stroke among those with cardiovascular disease.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateNov 12, 2025
A new genetic risk score combines rare and common gene variants with non-coding genome information to predict arrhythmia risk. This comprehensive framework can be applied to other genetically influenced diseases like cancer and Parkinson's Disease.
Sanjay Rajagopalan, a leading expert in cardiovascular medicine, has been recognized for his pioneering work on the impact of environmental risk factors on heart health. His research has informed public health policies worldwide and led to new understanding of how air pollution affects cardiovascular health.
In a clinical trial of 12,257 patients at high risk, investigators found that adding the drug evolocumab to a patient’s treatment reduced the risk of a first heart attack, first stroke, or coronary heart disease death by 25%. The study also showed a 36% reduction in heart attacks and a nominally lower rate of death in the evolocumab arm.
A nationwide study from the Hebrew University of Jerusalem found that adolescents with migraines are three times more likely to have high blood pressure. The research suggests that early blood pressure screening for teens with migraines could help detect cardiovascular risks before they develop into chronic disease.
A large-scale study published in the European Heart Journal found no increased risk of heart attack and stroke among transgender women taking hormone oestradiol. In contrast, transgender men using testosterone have a higher risk due to factors such as high blood pressure and poorer cholesterol levels.
The American Heart Association's inaugural CarePlan Challenge recognizes innovators who create digital solutions that transform preventive care, improve disease management and enhance patient engagement. The selected solutions showcase integration of the Association's science-based CarePlans and other digital tools.
A modeling study suggests that achieving systolic blood pressure equilibrium would significantly decrease the number of cardiovascular disease events and fatalities experienced by non-Hispanic black U.S. adults. Initiatives to maintain normal blood pressure and control hypertension could substantially improve health equity in the U.S.
A recent study from Houston Methodist reveals how Alzheimer's can disrupt the connection between nerves and blood vessels in fat tissue, worsening heart and metabolic conditions. The research highlights a potential link between neurodegeneration and cardiovascular and metabolic disorders.
A new study found that combining GLP-1 receptor agonist medications with healthy lifestyle habits significantly reduces the risk of major adverse cardiovascular events, including heart attacks and strokes. The research suggests that adopting multiple healthy behaviors can lower cardiovascular risk even further.
A study found that following steps to improve cardiovascular health can reduce the risk of mild cognitive impairment and dementia among people with Type 2 diabetes. Maintaining optimal cardiovascular health may protect brain health even for individuals with a high genetic risk for dementia.
Cardiac rehabilitation significantly improves short and long-term recovery for heart surgery patients, but women participate less than men due to barriers such as lower referral rates, clinician bias, and caregiving responsibilities. The American Heart Association scientific statement calls for targeted interventions to improve enrollm...
A cross-sectional study found associations between structural racism and inequities in neighborhood cardiovascular health, highlighting the need for targeted prevention efforts. The study's findings underscore the critical role of addressing systemic inequalities in promoting health equity.
The American Heart Association's Hearts on the Court Collective aims to raise awareness of cardiovascular disease in women through public service announcements and education. Led by LSU women's basketball coach Kim Mulkey, the collective is committed to empowering fans and student athletes to take charge of their cardiovascular health.
A new resource identifies genetic variants associated with elevated 'bad' cholesterol, a major contributor to heart disease. Clinicians can now predict patient risk for heart attacks and strokes, allowing for prevention and early treatment.
The Lehigh University team created a computational model to predict the hemodynamic response of patients with AFib, helping tailor neurostimulation dosages. The model validated against clinical data and predicted accurate effects on blood pressure, heart rate, and stroke volume.
The American Heart Association launches a new certification program to equip healthcare providers with digital tools to manage chronic conditions remotely. The certification aims to standardize training and validate expertise in delivering care in technology-enabled clinical settings, promoting better patient engagement and outcomes.
A large international study found that utilizing sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine DES implantation for treating de novo coronary artery disease. The results showed comparable outcomes, including low rates of cardiac death and target vessel myocardial infarction.
The study found that cutting balloon angioplasty is noninferior to intravascular lithotripsy in treating calcified coronary artery disease. The procedure is also less costly, making it a reasonable strategy for managing significantly calcified lesions.
A prospective cohort study found that individuals who accumulate their daily steps in longer bouts have a lower risk of mortality and cardiovascular disease. In sedentary participants, the association between longer stepping bouts and lower risk was more pronounced.
A novel post-translational modification, lactylation, plays a critical role in the pathogenesis of aortic dissection. Lactylation of mitochondrial adenosine triphosphate synthase subunit alpha impairs ATP production and increases reactive oxygen species generation.
The Cardiovascular Research Foundation (CRF) has announced the 2025 SET-10 Rankings, honoring institutions whose groundbreaking research is shaping the future of cardiovascular care. The rankings recognize academic and medical institutions that are advancing the science and improving patient outcomes.
A cohort study found that night light exposure was a significant risk factor for developing cardiovascular diseases among adults over 40. Avoiding light at night may be a useful strategy for reducing the risks of cardiovascular diseases.
A large-scale cohort study found that stopping drinking even at low levels can lead to clinically meaningful reductions in blood pressure. Researchers analyzed data from over 359,000 adults and discovered that quantity of alcohol intake is the primary driver of blood pressure changes.
A new study published in The Lancet found that semaglutide, a 'weight loss' drug, can help prevent heart attacks and other major cardiac events, regardless of the amount of weight people lose. The study suggests there are multiple ways the drug benefits the heart, beyond its protective effect on cardiovascular health.
A Northwestern University study found that Chicago parents have low intake of omega-3 fatty acids, specifically EPA and DHA, with women consuming even lower amounts. This deficiency may have direct negative effects on children's health, including preterm birth risk.
The American Heart Association found that nearly 9 in 10 US adults haven't heard of CKM syndrome, a condition affecting heart disease, kidney disease, diabetes, and obesity. The association is providing resources to help people understand the connection between heart, kidney, and metabolic health.
A recent study found that fish oil supplements can lower cardiovascular disease risk even in healthy individuals, with effects varying greatly between people. The study showed that EPA supplementation improved blood lipid profiles and reduced lipoprotein attachment to arterial walls.
Mike Leach, the mastermind of the air raid offense, will be recognized posthumously for his exceptional contributions to college football. The American Heart Association's Paul “Bear” Bryant Heart of a Champion Award honors Leach's larger-than-life impact on the game and communities he touched.
The American Heart Association has released its 2025 Coach of the Year Award watch list, featuring 28 college football coaches. The award, presented annually, recognizes coaching excellence that promotes grit, integrity, and a winning approach to both on-field performance and off-field life.
This study found that GLP-1RAs and SGLT2is offer the greatest cardiovascular benefits for adults with type 2 diabetes. The magnitude of benefit depends on baseline age, atherosclerotic cardiovascular disease, heart failure, and kidney impairment.
Researchers found that diets rich in plant-based products of higher nutritional quality, with little or no industrial processing, were associated with a 40% lower risk of cardiovascular disease. In contrast, ultra-processed plant-based foods showed no protective effect.
The 2025 Cardiovascular Provider Compensation and Production Survey found a 21% increase in cardiovascular providers represented, with data from 232 programs submitted. The report highlights adaptations in care delivery, including a drop in physician FTEs per 1,000 active patients as apps assume more responsibility.
The analysis of 2024 English voting patterns suggests that poorer health is associated with higher proportions of votes for Reform UK. This finding highlights the need for policymakers to address health inequalities and improve public health.
Phillip Fulmer, legendary University of Tennessee football coach, is the recipient of the American Heart Association’s 2026 Paul “Bear” Bryant Lifetime Achievement Award. The honor recognizes his outstanding career achievements and contributions to the sport.
Researchers developed a new model to predict risk of subsequent cardiovascular events in patients with ASCVD, outperforming current guidelines. The novel scoring tools use readily available clinical factors and blood assays, enabling easier, faster clinical translation.
Researchers use AI, omics, and systems biology to design targeted drugs for cardiovascular disease pathways. The tools could transform heart drug development and save lives, but global health policy leadership is urgently needed.
The American College of Cardiology has launched a new education program to educate clinicians on the latest advances in heart failure management and treatment. The program aims to improve outcomes among patients with heart failure by providing education on tailored treatments for different subtypes of HF.
A prospective cohort study found that young adults experiencing unfavorable patterns of cardiovascular health are at a marked increased risk for incident cardiovascular disease. Achieving and maintaining high cardiovascular health throughout young adulthood is crucial for preventing later-life cardiovascular disease.
The review highlights the critical roles of phospholipids in regulating immune cell migration, differentiation, and survival, as well as their regulatory effects on inflammation. Dysregulated phospholipid metabolism is linked to various diseases, including autoimmune disorders, cardiovascular disease, and cancer.
Dr. Judith Hochman will receive the 2025 Research Achievement Award for her significant research on revascularization and women's cardiovascular health. Her work has directly impacted clinical practice guidelines, particularly in ischemic heart disease.
The American Heart Association has acquired the Cardiometabolic Center Alliance program, strengthening efforts to provide holistic management of cardiovascular, kidney, and metabolic health. This partnership aims to expand patient-centered care and improve outcomes for patients with cardiometabolic disease.
Dr. Nicole Bhave has been named the ACC Annual Scientific Session vice chair and will lead the development of the educational program at ACC.27 and ACC.28. She also serves as a two-year meeting chair from ACC.29 to ACC.30.
A phase 3 clinical trial found that sotatercept significantly reduces the likelihood of worsening disease in patients with severe pulmonary hypertension when added to standard treatment within the first year after diagnosis. The medication reduced the risk of deterioration by 76% and hospitalizations by nearly half.
The SHC-SHG program leads to a 16% reduction in LRDs among self-employed individuals, while unemployed individuals show significant behavioral changes but not health improvements. The increase in municipal funds is found to be cost-effective, with overall medical expenses reduced by nine times the increase.