About The Study: In this cohort and nested case-control study among CARDIA (Coronary Artery Risk Development in Young Adults; a prospective study) participants, moderate to vigorous–intensity physical activity (MVPA) declined from early adulthood to midlife then plateaued, with notable demographic differences; cases experienced steep declines before cardiovascular disease (CVD), and gaps compared to controls persisted afterward. Black women had the lowest MVPA across adulthood and the highest risk of low MVPA post-CVD, underscoring the need to support lifelong physical activity and address group differences.
Corresponding Author: To contact the corresponding author, Yariv Gerber, PhD, email yarivg@tauex.tau.ac.il .
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(doi:10.1001/jamacardio.2025.2282)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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JAMA Cardiology