A study published in The Journal of Neuroscience found that chronic back pain is associated with a significant decrease in gray matter volume in the brain, particularly in regions involved in processing information and memory. This suggests that proper treatment may reverse some of the brain changes caused by chronic pain.
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A new neurostimulation system uses continuous electric field adjustments to provide real-time, dynamic paresthesia steering for improved pain relief. This innovative technology enables up to 71 combinations of stimulation settings, leading to enhanced therapeutic possibilities.
The KRONUS-MSP trial found that switching to sustained-release opioid Kadian improves pain relief and quality of life, while reducing the need for medication. Patients who previously exceeded recommended doses of OxyContin or MS Contin found relief with Kadian.
Researchers developed a new technique to selectively delete C-fiber neurons, which transmit chronic pain signals, using the drug resiniferatoxin. In animal studies, this approach reduced pain and improved behavior without side effects.
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Researchers found that 3% of women report chronic pain and 1.7% currently have pain, affecting millions across the US. The study also revealed that African-American women are as likely to experience vulvodynia as Caucasian women.
Researchers found naked mole-rats naturally lack Substance P, a neurotransmitter that sends pain signals to the central nervous system. Introducing Substance P restored pain signaling in these animals, sparking hope for new therapies to treat fibromyalgia.
A study found that patients with unexplained chronic fatigue had nine times more prevalent sinus symptoms than the control group, and six times more common in those with unexplained chronic pain. Sinusitis may be a contributing factor to chronic fatigue syndrome in some cases.
African Americans with chronic pain experience significantly more symptoms than whites when seeking treatment, including greater levels of pain, depression, and impairment. Economic factors also play a significant role in producing these disparities.
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A Stanford study found a significant link between depression and chronic pain, suggesting that pain may guide doctors to effective treatments for depressed patients. The research also indicates that continuous pain increases the likelihood of major depressive disorder diagnosis.
Researchers at the University of Melbourne have developed a new compound, ACV1, derived from cone shell venom that is more powerful and longer-lasting than morphine. The compound has shown promising results in laboratory studies, treating pain by blocking transmission along peripheral nervous systems without addictive side effects.
A new study reveals that rats with chronic pain from inflammation were more tolerant of painful heat stimuli and had less swelling when fed a diet based on soy protein. The findings suggest that a soy diet may reduce the need for opioid medications, which are often associated with severe side effects.
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A study of 4,832 medical residents found that one-tenth feel unprepared to handle tasks like HIV/AIDS treatment, substance abuse, and chronic pain management. Residents reported a positive view of their training for common clinical problems but expressed concern about inadequate preparation for non-traditional patient populations.
A systematic review of literature found an association between positive expectations and improved outcomes in myocardial infarction, cardiac surgery, chronic pain, and psychiatric conditions. The mechanisms behind this association are still uncertain, with questions surrounding causality versus prediction.
A recent survey in the Netherlands reveals that chronic pain affects approximately 18% of the population, with frequent problems including lower back pain and abdominal pain. The study highlights the need for more research into the effects of treatment methods, as current evidence is often inadequate or contradictory.
Scientists have relieved pain in rats by dispatching molecular 'smart bombs' to selectively destroy certain nerve cells in the spinal cord, targeting faulty signaling by a small group of neurons. This approach targets just those nerve cells that send pain messages to the brain without causing side effects like morphine or surgery.
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Researchers at the University of Florida found that women with chronic pain report slightly higher levels of pain than men. This difference may be attributed to how society teaches men to handle discomfort, rather than biology alone. The study's findings have long-term implications for treating male and female patients differently.
University of Florida researchers report that psychological effects of chronic pain are more disruptive to daily life than the pain itself. The study found that nearly 200 patients with TMD experienced depression, anger, and anxiety due to their condition.