Articles tagged with Chronic Pain
Researchers used a new imaging technique to study brain activity in patients with chronic low back pain, finding increased activity in specific brain regions during worsening pain episodes. The study provides insights into the basic physiology of pain processing and may lead to tailored therapies.
A study by St. Michael's Hospital found that nearly half of homeless people with chronic pain use street drugs to treat their condition, highlighting the need for improved approaches to managing chronic pain in this population. The study also highlights the importance of community outreach programs and education for healthcare provider...
The study highlights large gaps in the evidence base for treating chronic non-cancer pain, emphasizing the need for a multi-faceted approach that considers physical and emotional functioning. Researchers urge further investigation into combination treatments to identify effective therapies for specific patient characteristics.
Despite new guidelines and educational efforts, up to 75% of surgical patients in the USA still fail to receive adequate post-op pain relief. New pain medications and techniques under development could help improve symptom relief for patients.
A molecular imaging procedure using PET/CT and F18 NaF radiotracer accurately diagnoses and manages chronic back pain by pinpointing the source of abnormal bone reaction. In a study, this method was found to be highly effective in more than 85% of cases, providing relief for patients with hardware implants or bone grafts.
Improved pain management can significantly reduce disability in older adults, associated with increased sleep difficulty and numerous problems. Strategies include physical activity, pain protocol interventions, and medication use to optimize patient well-being.
Researchers at UC Davis have discovered a link between two major biological pathways involved in pain, which may pave the way for new treatments. The study found that inhibitors of the enzyme sEH can alleviate debilitating pain by targeting the messenger cAMP.
Primary care providers experience stress and guilt when managing chronic pain, often feeling ineffective and frustrated. Strategies to ease these frustrations are crucial for improving pain management from both patient and provider perspectives.
Chronic pain affects up to 30% of adults in Europe, impacting everyday lives and workability. Patients find managing pain requires adapting lifestyle, discovering new ways to express themselves, and engaging in activities that bring joy and social interaction.
The new guidelines, published in CMAJ, focus on identifying and managing fractures and assessing risk. Current data indicate that many fracture patients are not appropriately assessed or treated, highlighting the need for improved management of osteoporosis and fragility fractures.
Research by Elizabeth Sweeney examines how biomedical tests diagnose and define pain, leading to emotional suffering for patients with unexplained conditions. The study analyzes over 20 articles from the journal Pain®, highlighting challenges in diagnosing chronic pain.
Research suggests that women experience chronic pain longer, more intensely, and more often than men due to hormonal and social factors. Treating both physical and mental symptoms is crucial for effective management of chronic pain in women.
Researchers at the Hebrew University of Jerusalem have identified a gene associated with chronic pain susceptibility in humans. They found that genetic variants of Cacng2 were significantly associated with chronic pain in breast cancer patients after breast removal surgery, suggesting a potential link between genetics and pain perception.
Researchers have identified a gene, CACGN2, associated with chronic pain susceptibility in humans. The study suggests that genetic variants in this gene may contribute to individual differences in chronic pain experience.
A new study found that meditation lessens the perception of pain in individuals with a higher level of meditation experience. This method may have potential as an additional therapy option for treating chronic pain.
Researchers found over 2,000 genes reprogrammed in peripheral nervous system of rodent models, leading to potential 'transcription therapy' for chronic pain. The study's high-throughput sequencing revealed novel exons and gene candidates, offering a new approach for neuroscientific research.
A U-M study reveals that socio-economic factors, particularly race and age, significantly influence the use of alternative therapies like acupuncture and biofeedback in chronic pain patients. As people age, they are more likely to seek alternative therapies to manage chronic pain.
A University of Michigan Health System study found black men with chronic pain experience more severe symptoms, leading to increased disability and depression. The study highlights the need for a culturally appropriate approach to caring for black men with chronic pain.
Research reveals chronic pain changes brain activity in response to acute pain, predicting worsening of ongoing back pain. The nucleus accumbens plays a key role in this process, with altered activity patterns in patients compared to healthy controls.
Researchers at MDC developed a system to investigate ion channel function in mammals and block them with neurotoxins. They used genetic engineering to deliver toxin genes into neurons, enabling long-lasting investigation of ion channels and blockade of chronic pain.
Researchers at the University of Liverpool have discovered a single low dose infusion of intravenous immunoglobulin (IVIG) significantly reduces pain in patients with Complex Regional Pain Syndrome (CRPS), improving quality of life. The treatment has few adverse effects and can be repeated every four weeks.
Health consumers must become informed advocates for comprehensive pain treatment as physicians struggle with inadequate training and fear of prescription drug abuse. Long-term solutions require education, responsibility, and collaboration among all parties involved.
A new study reveals that chronic musculoskeletal pain in older adults significantly increases their risk of falls. The research found that participants with chronic pain in two or more joints had a 50% greater risk of falling compared to those with no pain.
Chronic musculoskeletal pain in two or more locations and high levels of severe pain are linked to a higher risk of falls in older adults. The study found that participants who reported chronic pain had an increased rate of falls, with those reporting the highest levels of pain severity also at elevated risk.
A study of 3,754 women found that nearly 50% experience pain symptoms 2-3 years after breast cancer treatment, with young age and supplemental radiation therapy increasing the risk. The most common areas affected by pain are the axilla, arm, breast area, and side of the body.
Researchers at Boston University School of Medicine developed an integrated treatment program combining cognitive processing therapy for PTSD and cognitive-behavioral therapy for chronic pain management. The pilot study found significant benefits in reducing symptoms of PTSD and chronic pain among veterans.
Chronic pain affects 80% of those living with it, and up to 10% gain access to effective treatments; a national strategy is long overdue to address the issue's significant economic and personal burden.
A recent study found that healthcare staff and relatives struggle to accurately diagnose pain levels in nursing home residents, particularly those with cognitive impairments. The researchers recommend increasing education on non-drug pain management strategies, such as massage, mobility, and music therapy, to improve care.
Researchers at the University of Michigan used brain imaging to study the effects of acupuncture on chronic pain. They found that traditional Chinese acupuncture increases binding availability of mu-opoid receptors in regions processing and dampening pain signals, leading to reduced pain levels.
Researchers at Boston Children's Hospital have created a slow-release anesthetic drug-delivery system, showing promise for prolonged pain relief without toxicity in rats. The formulation, using liposomes to package saxitoxin, produced nerve blocks lasting two days or seven days when combined with dexamethasone.
A new standardized tool for assessing chronic pain has been developed and validated to differentiate between peripheral neuropathic pain and non-neuropathic low back pain. The tool, called STEP, takes just 10-15 minutes to administer and has been shown to have high diagnostic accuracy.
A collaborative care intervention improved pain-related disability and intensity in patients with chronic noncancer pain compared to usual care. The program, which included patient and clinician education and symptom monitoring, showed significant improvements in depression and functional status.
A Mayo Clinic study found a correlation between inadequate vitamin D levels and the amount of narcotic medication taken by patients with chronic pain. Patients with low vitamin D levels were taking nearly twice as much pain medication, experiencing worse physical functioning and overall health perception.
A recent study in mice found that high levels of EAAT2 protein decreased abdominal pain by 50-70%. The protein acts on glutamate, preventing it from interacting with receptors that send pain signals. Researchers hope EAAT2 may treat visceral pain associated with gastrointestinal disorders like IBS.
Researchers at Northwestern University's Feinberg School of Medicine discovered a link between chronic pain and brain rewiring in complex region pain syndrome (CRPS). The study found changes in the brain's white matter, which dispatch messages between neurons, contributing to the condition.
The study found that individuals with depression exhibit increased activation in the right amygdala during painful stimulation, while displaying decreased activation in areas responsible for pain modulation. This suggests a relationship between depression and pain perception, with potential implications for treatment outcomes.
Researchers found black patients with chronic pain were less likely to have their weight or BMI recorded, despite being at higher risk for obesity. Obesity contributes to greater disability and poorer functioning over and above the impact of pain level.
A new two-week self-management programme significantly reduces healthcare visits, pain scores, and health distress in arthritis patients with chronic pain. The programme's benefits were sustained for six months with continued improvements up to a year later.
Recent studies on pain medicine highlight the need for personalized treatment approaches. Researchers found that opioid therapy often lacks sufficient trial duration to determine its effectiveness for chronic pain sufferers.
A University of Iowa study reveals a biological link between pain and fatigue, with a protein called ASIC3 playing a crucial role in protecting against muscle fatigue in women. Women are more likely to be diagnosed with chronic pain conditions like fibromyalgia and chronic fatigue syndrome due to hormonal differences.
According to a study of 3,047 trauma patients, most experience moderately severe pain one year after injury. Pain severity is highest in joints and extremities, and varies by age and sex, with younger adults more likely to experience pain than older adults.
The American Academy of Pain Medicine acknowledges chronic pain as a major disease entity, requiring targeted therapies. Studies estimate over 76 million Americans experience chronic pain, resulting in $1.85 billion annual cost.
Researchers present studies on the relationship between smoking and neuropathic pain, the benefits of physical conditioning in chronic pain patients, and the effectiveness of pain rehabilitation programs in reducing medication costs. These findings highlight the importance of addressing underlying causes of chronic pain and exploring n...
A study by Northwestern University's Feinberg School of Medicine found that chronic pain disrupts the equilibrium of the brain's regions, leading to permanent damage. This constant firing of neurons can alter connections and even cause death.
Researchers at Mount Sinai School of Medicine have discovered a novel targeted gene therapy that simulates the pain-killing effect of opiate drugs, providing relief for more than three months after a single injection. The technique targets selectively the pain gate, avoiding unwanted side effects associated with opioid painkillers.
Researchers found peroxynitrite plays a crucial role in opiate-induced antinociceptive tolerance in mice. Accumulation of tyrosine-nitrated proteins and oxidative DNA damage were associated with this process.
The International Association for the Study of Pain (IASP) has declared 2008 as the Global Year Against Pain in Women, highlighting the suffering caused by disparities in pain recognition and treatment. The campaign aims to increase awareness, empower women to seek proper treatment, and improve access to healthcare services.
A study at McGill University Health Centre shows that combining methadone with innovative case management can provide relief for patients with chronic pain. The program, which includes regular phone calls and a pain diary, resulted in 57% of patients being satisfied or very satisfied after nine months.
A recent study found that chronic pain patients taking opioid therapy are at a higher risk of developing sleep apnea. The research, published in Pain Medicine, suggests a direct dose-response relationship between central sleep apnea and methadone and benzodiazepines.
Researchers at the University of Manchester have uncovered the structure of a key pain molecule, P2X receptors, using microscopic slime moulds. This breakthrough could lead to the development of new painkillers for chronic conditions like migraine and backache.
A Northwestern University researcher has found that old memory traces in the prefrontal cortex may trigger chronic pain. The discovery led to a new drug, D-Cycloserine, which controls persistent nerve pain by targeting the emotional suffering of pain.
Scientists have identified the TRPM8 receptor as responsible for sensing cold, which also mediates pain perception. The study provides a target for treating acute and chronic pain.
This article discusses various aspects of pain management, including the impact of depression and posttraumatic stress disorder (PTSD) on patient satisfaction. The study found that patients with both conditions were more likely to have a chronic medical condition and greater physical and psychosocial stressors.
Researchers at the University of Alberta have confirmed that chronic pain affects attention and memory in 67% of participants. Chronic pain can disrupt the maintenance of the memory trace required to hold information for processing.
A new study published in the journal Sleep found that sleep disturbance increases spontaneous pain in women. The study, conducted by Michael T. Smith and colleagues, used polysomnography to assess 32 healthy females and found that fragmented sleep profiles led to impaired natural pain control mechanisms.
Chronic pain has increased by 26% among US workers over the past decade, with most employees experiencing moderate to severe pain while still attending work. Employers are encouraged to invest in workplace wellness programs addressing chronic pain, as only 22% currently include such components.
A new review of studies found that psychological interventions are effective in reducing pain intensity and improving health-related quality of life. These approaches also yield improvements in depression, work-related disability, and daily living.
A study at UNC Chapel Hill found that specific genetic variants of the COMT gene can affect pain processing by altering messenger RNA secondary structure. The discovery may lead to more effective treatments for TMJD and other chronic pain conditions.
A randomized controlled trial found that osteoarthritis patients who received acupuncture treatment in addition to routine care showed significant improvements in symptoms and quality of life. The study's results suggest that acupuncture can be an effective treatment option for OA patients, with benefits lasting beyond the therapy period.
A specific gene variant, GCH1, affects both acute and chronic pain sensitivity in humans. The protective version of the gene reduces the risk of developing chronic post-surgical pain.